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DISPLAYING 5151 - 5200 OF 15805 RESULTS

Analysing data from patient-reported outcome and quality of life endpoints for cancer clinical trials: a start in setting international standards
The Lancet Oncology, ISSN: 14745488 14702045
Andrew Bottomley; Madeline Pe; Jeff A. Sloan; Ethan Basch; Franck Bonnetain; Melanie Calvert; Alicyn Campbell; Charles S. Cleeland; Kim Cocks; Laurence Collette; Amylou Dueck; Nancy Devlin; Hans-Henning Flechtner; Carolyn C. Gotay; Eva Greimel; Ingolf Griebsch; Mogens Groenvold; Jean-Francois Hamel; Madeleine King; Paul G Kluetz; Michael Koller; Daniel C Malone; Francesca Martinelli; Sandra A Mitchell; Carol M Moinpour; Jammbe Musoro; Daniel O'Connor; Kathy Oliver; Elisabeth Piault-Louis; Martine Piccart; Francisco L Pimentel; Chantal Quinten; Jaap C Reijneveld; Christoph Schürmann; Ashley Wilder Smith; Katherine M Soltys; Martin J. B. Taphoorn; Galina Velikova; Corneel Coens
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An alternative approach to ChIP-Seq normalization enables detection of genome-wide changes in histone H3 lysine 27 trimethylation upon EZH2 inhibition
PLoS ONE, ISSN: 19326203
Brian Egan; Chih-Chi Yuan; Madeleine Lisa Craske; Paul Labhart; Gulfem D. Guler; David Arnott; Tobias Maile; Jennifer Busby; Chisato Henry; Theresa K. Kelly; Charles Tindell; Suchit Jhunjhunwala; Feng Zhao; Charlie Hatton; Barbara M. Bryant; Marie Classon; Patrick Trojer
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Functional Reading Independence (Fri) index: A new patient-reported outcome measure for patients with geographic atrophy
Investigative Ophthalmology and Visual Science, ISSN: 15525783 01460404
Miriam Kimel; Nancy Kline Leidy; Elizabeth Tschosik; Chantal M. Dolan; Eric H. Souied; Rohit Varma; Neil M. Bressler
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Development and application of a microfluidics-based panel in the basal/luminal transcriptional characterization of archival bladder cancers
PLoS ONE, ISSN: 19326203
Doris Kim; Younjeong Choi; James S. Ireland; Oded Foreman; Rachel Tam; Rajesh Patel; Erica Schleifman; Maipelo Motlhabi; French; Cheryl Wong; Peters; Luciana L. Molinero; Rajiv Raja; Lukas Amler; Garret M. Hampton; Lackner; Omar Kabbarah
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Chromosomal instability estimation based on next generation sequencing and single cell genome wide copy number variation analysis
PLoS ONE, ISSN: 19326203
Stephanie B. Greene; Angel E. Dago; Laura J. Leitz; Yipeng Wang; Jerry Lee; Shannon L. Werner; Steven Gendreau; Premal Patel; Shidong Jia; Liangxuan Zhang; Eric K Tucker; Michael Malchiodi; Ryon P. Graf; Ryan Dittamore; Dena Marrinucci; Mark Landers
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Corticosteroid-related toxicity in patients with chronic idiopathic urticaria-chronic spontaneous urticaria
Allergy and Asthma Proceedings, ISSN: 15396304 10885412
Dennis Ledford; Michael S. Broder; Evgeniya Antonova; Theodore A. Omachi; Eunice Chang; Allan T. Luskin
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Measuring experimental cyclohexane-water distribution coefficients for the SAMPL5 challenge
Journal of Computer-Aided Molecular Design, ISSN: 15734951 0920654X
Ariën S. Rustenburg; Justin Dancer; Baiwei Lin; Jianwen A. Feng; Daniel F. Ortwine; David L. Mobley; John D. Chodera
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Common variants at PVT1, ATG13-AMBRA1, AHI1 and CLEC16A are associated with selective IgA deficiency
Nature Genetics, ISSN: 15461718 10614036
Paola G. Bronson; Diana Chang; Tushar Bhangale; Michael F. Seldin; Ward Ortmann; Ricardo C. Ferreira; Elena Urcelay; Luis Fernández Pereira; Javier Martin; Alessandro Plebani; Vassilios Lougaris; Vanda Friman; Tomáš Freiberger; Jiri Litzman; Vojtech Thon; Qiang Pan-Hammarström; Lennart Hammarström; Robert R. Graham; Timothy W. Behrens
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Transporter expression in liver tissue from subjects with alcoholic or hepatitis C cirrhosis quantified by targeted quantitative proteomics
Drug Metabolism and Disposition, ISSN: 1521009X 00909556
Li Wang; Carol Collins; Edward J. Kelly; Xiaoyan Chu; Adrian S. Ray; Laurent Salphati; Guangqing Xiao; Caroline A. Lee; Yurong Lai; Mingxiang Liao; Anita Mathias; Raymond Evers; W. Griffith Humphreys; Cornelis E. Hop; Sean C. Kumer; Jashvant D. Unadkat
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Rifampin-mediated induction of tamoxifen metabolism in a humanized PXR-CAR-CYP3A4/3A7-CYP2D6 mouse model
Drug Metabolism and Disposition, ISSN: 1521009X 00909556
Jae H. Chang; John Chen; Liling Liu; Kirsten Messick; Justin Ly
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Commercial biomarker assays: Friend and foe
Bioanalysis, ISSN: 17576199 17576180
Saloumeh Kadkhodayan Fischer; Montserrat Carrasco-Triguero; Kyu Hong; Jeremy Good; Teresa Davancaze; Trung Nguy; Jessica Li; Darbonne; Alyssa M. Morimoto; Yuda Zhu
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Characterization of IL-17AA and IL-17FF in rheumatoid arthritis and multiple sclerosis
Bioanalysis, ISSN: 17576199 17576180
Cheryl A. Schofield; Saloumeh Kadkhodayan Fischer; Michael J. Townsend; Mosesova; Kun Peng; A F. Setiadi; An Song; Amos Baruch
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Issues facing the bioanalytical community: Summary of round table discussions
Bioanalysis, ISSN: 17576199 17576180
Neil Spooner; Stephanie Cape; Roger Hayes; Surinder Kaur; John Kolman; Steve Lowes; Scott Summerfield; Amanda Wilson; Eric Woolf
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Fit-for-purpose biomarker immunoassay qualification and validation: Three case studies
Bioanalysis, ISSN: 17576199 17576180
Kyra J. Cowan; Xiaoying Gao; Vaishali Parab; Trung Nguy; Lawren C. Wu; Joseph R. Arron; Michael J. Townsend; Jeffery J. Wallin; Melissa Cheu; Alyssa M. Morimoto; Eric Wakshull
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Precision of pharmaceutical powder flow measurement using ring shear tester: High variability is inherent to powders with low cohesion
Powder Technology, ISSN: 1873328X 00325910
Lap Yin Leung; Chen Mao; Li Ping Chen; Yi Yang
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A practical guide to assess the Nancy histological index for UC
Gut, ISSN: 14683288 00175749
Aude Marchal-Bressenot; Alexis Scherl; Julia Salleron; Peyrin-Biroulet
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Strategies to Determine Assay Format for the Assessment of Neutralizing Antibody Responses to Biotherapeutics
AAPS Journal, ISSN: 15507416
Bonnie Wu; Shan Chung; Xu-Rong Jiang; Jim McNally; Joao Pedras-Vasconcelos; Renuka Pillutla; Joleen T. White; Yuanxin Xu; Shalini Gupta
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Adverse event-related costs for systemic metastatic breast cancer treatment among female Medicaid beneficiaries
Journal of Medical Economics, ISSN: 1941837X 13696998
Debra E. Irwin; Anthony Masaquel; Stephen S. Johnston; Brian Barnett
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The economic burden of end-of-life care in metastatic breast cancer
Journal of Medical Economics, ISSN: 1941837X 13696998
Thomas Bramley; Vincent Antao; Orsolya Lunacsek; Kristin Hennenfent; Anthony Masaquel
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Mechanisms of mitophagy: PINK1, Parkin, USP30 and beyond
Free Radical Biology and Medicine, ISSN: 18734596 08915849
Baris Bingol; Morgan Sheng
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Evaluation of Cytochrome P450 3A4-Mediated Drug–Drug Interaction Potential for Cobimetinib Using Physiologically Based Pharmacokinetic Modeling and Simulation
Clinical Pharmacokinetics, ISSN: 11791926 03125963
Nageshwar Budha; Tao Ji; Luna Musib; Stephen M. Eppler; Mark J. Dresser; Yuan Chen; Jin Y. Jin
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In vivo evaluation of retinal ganglion cells degeneration in eyes with branch retinal vein occlusion
British Journal of Ophthalmology, ISSN: 14682079 00071161
Rayan A. Alshareef; Giulio Barteselli; Qisheng You; Abhilash Goud; Asiya Jabeen; Harsha L. Rao; Asiya Jabeen; Jay Chhablani
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GluN2A-selective pyridopyrimidinone series of nmdar positive allosteric modulators with an improved in vivo profile
ACS Medicinal Chemistry Letters, ISSN: 19485875
Elisia Villemure; Matthew Volgraf; Yu Jiang; Guosheng Wu; Cuong Q. Ly; Po-Wai Yuen; Aijun Lu; Xifeng Luo; Mingcui Liu; Shun Zhang; Patrick J. Lupardus; Heidi J. A. Wallweber; Bianca M. Liederer; Gauri Deshmukh; Emile G. Plise; Suzanne Tay; Tzu-Ming Wang; Jesse E. Hanson; David Hackos; Kimberly Scearce-Levie; Jacob B. Schwarz; Benjamin D. Sellers
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Randomized phase II study of duligotuzumab (MEHD7945A) vs. cetuximab in squamous cell carcinoma of the head and neck (MEHGAN study)
Frontiers in Oncology, ISSN: 2234943X
Jérôme Fayette; Lori Wirth; Cristina Marinela Oprean; Anghel Udrea; Antonio Jimeno; Danny Rischin; Christopher Nutting; Paul M. Harari; Tibor Csoszi; Dana Cernea; Paul O'Brien; William D. Hanley; Amy V. Kapp; Maria Anderson; Elicia M. Penuel; Bruce Mccall; Andrea Pirzkall; Jan B. Vermorken
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The Nedd4-2/Ndfip1 axis is a negative regulator of IgE-mediated mast cell activation
Nature Communications, ISSN: 20411723
Kwok Ho Yip; Natasha Kolesnikoff; Nicholas Hauschild; Lisa Biggs; Angel F. Lopez; Stephen J. Galli; Kumar; Michele A. Grimbaldeston
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Introduction
Analysis of Post-Translational Modifications Using Mass Spectrometry,
Rebecca R. Pferdehirt; Florian Gnad; Jennie R. Lill
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Reprint of “Mixed-mode chromatography in pharmaceutical and biopharmaceutical applications”
Journal of Pharmaceutical and Biomedical Analysis, ISSN: 1873264X 07317085
Kelly Zhang; Xiaodong Liu
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Health care resource use and costs associated with possible side effects of high oral corticosteroid use in asthma: A claims-based analysis
ClinicoEconomics and Outcomes Research, ISSN: 11786981
Allan T. Luskin; Evgeniya Antonova; Michael S. Broder; Eunice Chang; Theodore A. Omachi; Dennis Ledford
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Battling Btk Mutants with Noncovalent Inhibitors That Overcome Cys481 and Thr474 Mutations
ACS Chemical Biology, ISSN: 15548937 15548929
Adam R. Johnson; Pawan Bir Kohli; Arna Katewa; Emily Gogol; Lisa D. Belmont; Regina Choy; Elicia M. Penuel; Luciana Burton; Eigenbrot; Christine Yu; Daniel F. Ortwine; Krista K. Bowman; Yvonne Franke; Christine Tam; Alberto Estevez; Kyle Mortara; Jiansheng Wu; Hong Li; May Lin; Philippe Bergeron; James J. Crawford; Wendy B. Young
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Genetic Adaptation and Neandertal Admixture Shaped the Immune System of Human Populations
Cell, ISSN: 10974172 00928674
Hélène Quach; Maxime Rotival; Julien Pothlichet; Yong-Hwee Eddie Loh; Michael Dannemann; Nora Zidane; Guillaume Laval; Etienne Patin; Christine Harmant; Marie Lopez; Matthieu Deschamps; Nadia Naffakh; Darragh Duffy; Anja Coen; Geert Leroux-Roels; Frederic Clément; Anne Boland; Jean-François Deleuze; Janet Kelso; Matthew L. Albert; Lluis Quintana-Murci
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IL-27 directly enhances germinal center b cell activity and potentiates lupus in sanroque mice
Journal of Immunology, ISSN: 15506606 00221767
Dipti Vijayan; Norhanani Mohd Redzwan; Danielle T. Avery; Rushika C. Wirasinha; Robert Brink; Giles Walters; Stephen Adelstein; Masao Kobayashi; Paul Gray; Michael Elliott; Melanie Wong; Cecile King; Carola G. Vinuesa; Nico Ghilardi; Cindy S. Ma; Stuart G. Tangye; Marcel Batten
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Cell Active Hydroxylactam Inhibitors of Human Lactate Dehydrogenase with Oral Bioavailability in Mice
ACS Medicinal Chemistry Letters, ISSN: 19485875
Hans E. Purkey; Kirk D. Robarge; Jinhua Chen; Zhongguo Chen; Laura B. Corson; Charles Z. Ding; Antonio G. DiPasquale; Peter Dragovich; Eigenbrot; Marie Evangelista; Benjamin P. Fauber; Zhenting Gao; Hongxiu Ge; Anna Hitz; Qunh Ho; Sharada Labadie; Kwong Wah Lai; Wenfeng Liu; Yajing Liu; Chiho Li; Shuguang Ma; Shiva Malek; Thomas O'Brien; Jodie Pang; David Peterson; Laurent Salphati; Steve Sideris; Ultsch; Binqing Wei; Ivana Yen; Qin Yue; Huihui Zhang; Aihe Zhou
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Discovery of a Noncovalent, Mutant-Selective Epidermal Growth Factor Receptor Inhibitor
Journal of Medicinal Chemistry, ISSN: 15204804 00222623
Bryan K. Chan; Emily J. Hanan; Krista K. Bowman; Marian C. Bryan; Burdick; Emily Chan; Yuan Chen; Saundra Clausen; Trisha Dela Vega; Jennafer Dotson; Eigenbrot; Richard Elliott; Robert Heald; Philip Jackson; Jamie Knight; Hank La; Michael Lainchbury; Shiva Malek; Hans E. Purkey; Gabriele Schaefer; Stephen Schmidt; Eileen Seward; Steve Sideris; Lily Shao; Shumei Wang; Siew Kuen Yeap; Ivana Yen; Christine Yu; Timothy P. Heffron
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Cellular uptake of a cystine-knot peptide and modulation of its intracellular trafficking
Scientific Reports, ISSN: 20452322
Xinxin Gao; Karen Stanger; Harini Kaluarachchi; Till Maurer; Paulina Ciepla; Cecile Chalouni; Yvonne Franke; Rami N. Hannoush
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Economic burden related to chemotherapy-related adverse events in patients with metastatic breast cancer in an integrated health care system
Breast Cancer: Targets and Therapy, ISSN: 11791314
Nazia Rashid; Han A. Koh; Hilda C. Baca; Kathy J. Lin; Susan Malecha; Anthony Masaquel
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A Method to Measure Protein Unfolding at an Air-Liquid Interface
Langmuir, ISSN: 15205827 07437463
Danielle L. Leiske; Ian C. Shieh; Martha Lovato Tse
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Preliminary safety and clinical activity of atezolizumab combined with cobimetinib and vemurafenib in BRAF V600-mutant metastatic melanoma
Annals of Oncology, ISSN: 15698041 09237534
Patrick Hwu; Omid Hamid; Rene Gonzalez; Jeffery R. Infante; Manish R. Patel; F. Stephen Hodi; Karl Lewis; Jeffery J. Wallin; Mwawasi; Edward Cha; Nicole A. Richie; Ballinger; Ryan J. Sullivan
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The SP142 PD-L1 IHC assay for atezolizumab (atezo) reflects pre-existing immune status in NSCLC and correlates with PD-L1 mRNA
Annals of Oncology, ISSN: 15698041 09237534
Williams; Marcin Kowanetz; Koeppen; Zachary Boyd; Edward E. Kadel III; Dustin Smith; Mark L. McCleland; Wei Zou; Priti Hegde
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Clinical activity, safety and predictive biomarkers results from a phase Ia atezolizumab (atezo) trial in extensive-stage small cell lung cancer (ES-SCLC)
Annals of Oncology, ISSN: 15698041 09237534
Lecia V. Sequist; Chiang; Gilbert; Michael S. Gordon; Paul Conkling; Thompson; Marcoux; Scott J. Antonia; Bo Liu; David S. Shames; Ariel Lopez-Chavez; Carol E. O'Hear; Marcella Fassò; Scott Gettinger
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SANDPIPER: Phase III study of the PI3-kinase (PI3K) inhibitor taselisib (GDC-0032) plus fulvestrant in patients (pts) with oestrogen receptor (ER)-positive, HER2-negative locally advanced or metastatic breast cancer (BC) enriched for pts with PIK3CA-mutant tumours
Annals of Oncology, ISSN: 15698041 09237534
Baselga; Cortes Castan; De Laurentiis; Diéras; Nadia Harbeck; Jerry Y. Hsu; Jin; Frauke Schimmoller; Wilson; Im; William Jacot; Ian E. Krop; Sunil Verma
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Genomic features of complete responders (CR) versus fast progressors (PD) in patients with BRAFV600-mutated metastatic melanoma treated with cobimetinib + vemurafenib or vemurafenib alone
Annals of Oncology, ISSN: 15698041 09237534
Yibing Yan; Caroline Robert; James Larkin; Paolo A. Ascierto; Brigitte Dréno; Michele Maio; Claus Garbe; Paul B. Chapman; Jeffrey A. Sosman; Matthew Wongchenko; Hsu; Chang; Ivor Caro; Isabelle Rooney; McArthur; Antoni Ribas
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Atezolizumab (atezo) in platinum (plat)-treated locally advanced/metastatic urothelial carcinoma (mUC): Updated OS, safety and biomarkers from the Ph II IMvigor210 study
Annals of Oncology, ISSN: 15698041 09237534
Yohann Loriot; Jonathan E. Rosenberg; Thomas Powles; Andrea Necchi; Syed Hussain; Morales; Margitta M. Retz; Günter Niegisch; Ignacio Durán; Christine Théodore; Jose Luis Perez-Gracia; Grande Pulido; AnnChristine Thåström; Bradford Danner; Sanjeev Mariathasan; Oyewale Abidoye; Michiel S Van Der Heijden
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First-line cobimetinib (C) + paclitaxel (P) in patients (pts) with advanced triple-negative breast cancer (TNBC): Updated results and tumoral immune cell infiltration data from the phase 2 COLET study
Annals of Oncology, ISSN: 15698041 09237534
David W. Miles; Sung-Bae Kim; Velu; Garcia-Saenz; Elizabeth Tan-Chiu; Sohn; Luc Dirix; Vanˇásek; Borms; J. Ilgado De Mingorance; Liu; Moezi; Kozloff; Joseph Sparano; Xu; Yibing Yan; Matthew Wongchenko; Brian Simmons; Virginia McNally; Adam Brufsky
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Primary analysis from OAK, a randomized phase III study comparing atezolizumab with docetaxel in 2L/3L NSCLC
Annals of Oncology, ISSN: 15698041 09237534
Fabrice Barlesi; Park; Fortunato Ciardiello; Joachim Von Pawel; Shirish M. Gadgeel; Hida; Dariusz M Kowalski; Manuel Cobo Dols; Diego L Cortinovis; Joseph W. Leach; Jonathan Polikoff; David R. Gandara; Carlos H. Barrios; Chen; Pei He; Marcin Kowanetz; Ballinger; Waterkamp; Alan Sandler; Achim Rittmeyer
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PTEN loss as a predictive biomarker for the Akt inhibitor ipatasertib combined with abiraterone acetate in patients with metastatic castration-resistant prostate cancer (mCRPC)
Annals of Oncology, ISSN: 15698041 09237534
De Bono; Ugo De Giorgi; Christophe Massard; Sergio Bracarda; Nava Rodrigues; Ivo Kocak; Albert Font; Jose Angel Arranz Arija; Shih; George Daniel Radavoi; Wei Yu; Wai Y. Chan; Steven Gendreau; Liangxuan Zhang; Ruth Riisnaes; Matthew Wongchenko; Daniel Maslyar; Viorel Jinga
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A phase I study evaluating DLYE5953A, an antibody-drug conjugate targeting the tumor-associated antigen lymphocyte antigen 6 complex locus E (Ly6E), in patients (Pts) with solid tumors
Annals of Oncology, ISSN: 15698041 09237534
Modi; Joseph Paul Eder; Patricia M. LoRusso; Colin D. Weekes; Sarat Chandarlapaty; Tolaney; McLaughlin; D. Ross Camidge; Chang; Denise Nazzal; Chen; Schuth; Flavia Brunstein; Darbonne; W. Michael Flanagan; Alexander Ungewickell; Geoffrey I. Shapiro
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Analytic validation of a clinical circulating tumor DNA assay for patients with solid tumors
Annals of Oncology, ISSN: 15698041 09237534
Phillip J. Stephens; Travis A. Clark; Mark Kennedy; He; Young; Mandy Zhao; Michael Coyne; Virginia Breese; Young; Shan Zhong; Mark Bailey; Bernard Fendler; Vincent A. Miller; Erica Schleifman; Peters; Geoff A. Otto; Doron Lipson; Jeffrey S. Ross
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Safety, clinical activity and biomarkers of atezolizumab (atezo) in advanced ovarian cancer (OC)
Annals of Oncology, ISSN: 15698041 09237534
Jeffery R. Infante; Fadi S. Braiteh; Leisha A. Emens; Ani Balmanoukian; Ana Oaknin; Yan Wang; Bo Liu; Luciana L. Molinero; Marcella Fassò; Carol E. O'Hear; Michael S. Gordon
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A retrospective, real-world study of treatment patterns and outcomes among metastatic urothelial cancer (mUC) patients in the United States
Annals of Oncology, ISSN: 15698041 09237534
Elisabetta Malangone-Monaco; Sacha Satram-Hoang; Kathleen Wilson; Helen Varker; Shih-Wen Lin; Darren Tayama; Sarika Ogale
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Tumor mutation load assessed by FoundationOne (FM1) is associated with improved efficacy of atezolizumab (atezo) in patients with advanced NSCLC
Annals of Oncology, ISSN: 15698041 09237534
Marcin Kowanetz; Wei Zou; David S. Shames; Cummings; Naiyer A. Rizvi; Alexander Spira; Garrett M Frampton; Vincent Leveque; Susan Flynn; Mocci; Geetha Shankar; Roel Funke; Ballinger; Waterkamp; Alan Sandler; Garret M. Hampton; Lukas Amler; Priti Hegde; Matthew D. Hellmann
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