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Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 51 - 100 OF 12534 RESULTS

Communications Biology, ISSN: 23993642
Andrew Ah Young; Sterling C. Eckard; Alvin Gogineni; Hongkang Xi; S. Jack Lin; Gerhardy; Christian Cox; Qui T. Phung; Jason Hackney; Anand Kumar Katakam; Mike Reichelt; Patrick Caplazi; Paolo Manzanillo; Juan Zhang; Meron Roose-Girma; Lucinda W. Tam; Robert J (Research) Newman; Aditya Murthy; Robby Weimer; Jennie Lill; Wyne P. Lee; Michele Grimbaldeston; Daniel Kirchhofer; Menno van Lookeren Campagne
Pan-cancer population pharmacokinetics and exposure-safety and -efficacy analyses of atezolizumab in patients with high tumor mutational burden
Pharmacology Research and Perspectives,
Colby S. Shemesh; Phyllis Chan; Fatema A. Legrand; David Shames; Meghna Das Thakur; Jane Shi; Lorna Bailey; Shweta Vadhavkar; Xian He; Wei Zhang; Rene A. Bruno
Cell Reports, ISSN: 22111247
Otto Morris; Hansong Deng; Christine Tam; Heinrich Jasper
Targeting Autophagy to Treat Cancer: Challenges and Opportunities
Frontiers in Pharmacology,
Junghyun Lim; Aditya Murthy
Practical Early Development Synthesis of Nav17 Inhibitor GDC-0310
Synthesis (Germany), ISSN: 00397881
Andy Stumpf; Frederic St-Jean; David Lao; Zhiyong (Jay) Cheng; Remy Angelaud; Francis Gosselin
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 10916490 00278424
Amos Baruch; Chin Wong; Leslie W. Chinn; Vaze; Jun Sonoda; Tom Gelzleichter; Shan Chen; Nicholas Lewin-Koh; Linda Morrow; Suresh Dheerendra; Richard Boismenu; Johnny Gutierrez; Eric Wakshull; Maria E. Wilson; Puneet S. Arora
Osteopontin Links Myeloid Activation and Disease Progression in Systemic Sclerosis
Cell Reports Medicine,
Xia Gao; Jim Jia; Anna Guttman; Daryle DePianto; Katrina B. Morshead; Kai-Hui Sun; Nandhini Ramamoorthi; Jason A. Vander Heiden; Zora Modrusan; Paul J. Wolters; Angelika Jahreis; Joe Arron; Dinesh Khanna; Thiru Ramalingam
Using differential scanning calorimetry for the development of non-reduced capillary electrophoresis sodium dodecyl sulfate methods for monoclonal antibodies
Analytical Biochemistry, ISSN: 00032697
Patricia Molina; Arthur J. Schick; Leslie Welch; Thomas Niedringhaus; Gabriella del Hierro; Galahad Deperalta; Aaron Hieb
Frontiers in Immunology, ISSN: 16643224
Steve Hack; Zhu; Yulei Wang
Improving Prediction of Free Fatty Acid Particle Formation in Biopharmaceutical Drug Products: Incorporating Ester Distribution during Polysorbate 20 Degradation
Molecular Pharmaceutics,
Nidhi Doshi; Joelle Martin; Anthony Tomlinson
Characterization of Tissue Distribution, Catabolism, and Elimination of an Anti-Staphylococcus aureus THIOMAB Antibody-Antibiotic Conjugate in Rats
Drug Metabolism and Disposition,
Hao Cai; Victor Yip; Violet Lee; Sylvia Wong; Ola Saad; Shuguang Ma; Nina Ljumanovic; S Cyrus Khojasteh; Amrita Kamath; Ben-Quan Shen
Eye, ISSN: 14765454 0950222X
Anthony Adamis; Christopher Brittain; Atul Dandekar; Jill Hopkins
Urology, ISSN: 15279995 00904295
Kyle A. Richards; Wenny Lin; Ching-Yi Chuo; Christina L. Derleth; Jingbo Yi; Marko Zivkovic; Sarika Ogale; Sandip Prasad; G. Joel Decastro; Gary D. Steinberg
Annals of the Rheumatic Diseases, ISSN: 14682060 00034967
Frances Humby; Myles J. Lewis; Michael Townsend; Costantino Pitzalis
AAPS Journal, ISSN: 15507416
Arian Emami Riedmaier; Kevin DeMent; James Huckle; Phil Bransford; Cordula Stillhart; Richard Lloyd; Ravindra Alluri; Sumit Basu; Yuan Chen; Varsha Dhamankar; Stephanie Dodd; Priyanka Kulkarni; Andrés Olivares-Morales; Chi-Chi Peng; Xavier Pepin; Xiaojun Ren; Thuy Tran; Christophe Tistaert; Tycho Heimbach; Filippos Kesisoglou; Christian Wagner; Neil Parrott
Impact of Silicone Oil on Free Fatty Acid Particle Formation due to Polysorbate 20 Degradation
Pharmaceutical Research, ISSN: 07248741
Raphael Fish; Jasper Lin; Nidhi Doshi
Water related impact of energy: Cost and carbon footprint analysis of water for biopharmaceuticals from tap to waste
Chemical Engineering Science: X,
Alessandro Luigi Cataldo; Bernhard Sissolak; Karl Metzger; Kristi Budzinski; Osamu Shirokizawa; Markus Luchner; Alois Jungbauer; Peter Satzer
Comparison of techniques to control ice nucleation during lyophilization
Processes,
Jake Luoma; Erika Ingham; Carmen Lema Martinez; Andrea Allmendinger
Frontiers in Immunology, ISSN: 16643224
Sébastien Wieckowski; Cécile Avenal; Arturo Orjalo; Daniel Gygax; Florian Cymer
Nature, ISSN: 14764687 00280836
Erik L. Bao; Satish K. Nandakumar; Xiaotian Liao; Alexander G. Bick; Juha Karjalainen; Marcin Tabaka; Olga I. Gan; Aki S. Havulinna; Tuomo T. J. Kiiskinen; Caleb A. Lareau; Aitzkoa L. de Lapuente Portilla; Bo Li; Connor Emdin; Veryan Codd; Christopher P. Nelson; Christopher J. Walker; Claire Churchhouse; Albert de la Chapelle; Daryl E. Klein; Björn Nilsson; Peter W. F. Wilson; Kelly Cho; Saiju Pyarajan; J. Michael Gaziano; Nilesh J. Samani; Aarno Palotie; Mark Daly; Howard Jacob; Heiko Runz; Sally John; Robert M. Plenge; Mark McCarthy; Dawn Waterworth; Caroline Fox; Anders Malarstig; Kathy Klinger; Kathy Call; Tomi P. Mäkelä; Jaakko Kaprio; Petri Virolainen; Kari Pulkki; Terhi Kilpi; Markus Perola; Jukka Partanen; Anne Pitkäranta; Riitta Kaarteenaho; Seppo Vainio; Veli-Matti Kosma; Urho Kujala; Jeff Waring; Heiko Runz; Jimmy Liu; Shameek Biswas; Dawn Waterworth; Meg Ehm; Caroline S. Fox; Anders Mälarstig; Catherine Marshall; Xinli Hu; Kathy Call; Kathy Klinger; Matthias Gossel; Samuli Ripatti; Johanna Sc
Journal of Medicinal Chemistry, ISSN: 15204804 00222623
Emily Hanan; Jun Liang; Xiaojing Wang; Robert Blake; Nicole Blaquiere; Steven Staben
Biochemistry, ISSN: 15204995 00062960
Nicholas P. D. Liau; Avinashnarayan Venkatanarayan; John Quinn; Wilson Phung; Shiva Malek; Sarah Hymowitz; Jawahar Sudhamsu
Bioorganic and Medicinal Chemistry Letters, ISSN: 14643405 0960894X
Keira Garland; Homer Pantua; Marie-Gabrielle Braun; Dan Burdick; Georgette Castanedo; Yi-Chen Chen; Yun-Xing Cheng; Jonathan Cheong; Blake Daniels; Gauri Deshmukh; Yuhong Fu; Paul Gibbons; Susan Gloor; Rongbao Hua; Sharada Labadie; Xiongcai Liu; Rich Pastor; Craig Stivala; Min Xu; Yiming Xu; Hao Zheng; Sharookh Kapadia; Emily Hanan
ACS Medicinal Chemistry Letters, ISSN: 19485875
Le Wang; George A. Doherty; Andrew S. Judd; Zhi-Fu Tao; T. Matthew Hansen; Robin R. Frey; Xiaohong Song; Bruncko; Aaron R. Kunzer; Xilu Wang; Michael D. Wendt; John Flygare; Nathaniel D. Catron; Russell A. Judge; Chang H. Park; Shashank Shekhar; Darren C. Phillips; Paul M. Nimmer; Morey L. Smith; Stephen K. Tahir; Yu Xiao; John Xue; Haichao Zhang; Phuong N. Le; Michael J. Mitten; Erwin R. Boghaert; Wenqing Gao; Peter J. Kovar; Edna Choo; Dolores Diaz; Wayne Fairbrother; Steven W. Elmore; Deepak Sampath; Joel D. Leverson; Andrew J. Souers
Journal of Clinical Pharmacology, ISSN: 15524604 00912700
Chunze Li; Shang-Chiung Chen; Yuan Chen; Sandhya Girish; Matts Kaagedal; Dan Lu; Tong Lu; Divya Samineni; Jin Y. Jin
Bioanalysis, ISSN: 17576199
Sally Fischer; Kathi Williams; Ian Harmon; Bryan Bothwell; Hua Xu; Emmanuel Capio; Mikhail Briman
Single-cell transcriptome profiling of the kidney glomerulus identifies key cell types and reactions to injury
Journal of the American Society of Nephrology, ISSN: 10466673
Jun-Jae Chung; Leonard Goldstein; Jasmine Chen; Jiyeon Lee; Webster; Meron Roose-Girma; Sharad C. Paudyal; Zora Modrusan; Anwesha Dey; Andrey Shaw
Autoimmunity linked protein phosphatase PTPN22 as a target for cancer immunotherapy
Journal for ImmunoTherapy of Cancer,
Rafael Cubas; Zia Khan; Qian Gong; Marina Moskalenko; Huizhong Xiong; Qinglin Ou; Christine Pai; Ryan Rodriguez; Jeanne Cheung; Andrew A. Chan
Atezolizumab for first-line treatment of PD-L1–selected patients with NSCLC
New England Journal of Medicine, ISSN: 00284793
Roy S. Herbst; Giuseppe Giaccone; Filippo De Marinis; Niels Reinmuth; Alain Vergnenegre; Carlos H. Barrios; Masahiro Morise; Enriqueta Felip; Zoran Andric; Sarayut Geater; Mustafa Özgüroğlu; Wei Zou; Alan Sandler; Ida Enquist; Kimberly Komatsubara; Deng; Hiroshi Kuriki; Wen; Mark McCleland; Simonetta Mocci; Jacek Jassem; David Spigel
Pulmonary Pharmacology and Therapeutics, ISSN: 15229629 10945539
John Busby; Cecile Holweg; Akiko Chai; Peter Bradding; Rekha Chaudhuri; Adel Mansur; John Matthews; Andrew Menzies-Gow; James Lordan; Robert Niven; Liam G. Heaney
Bioanalysis, ISSN: 17576199 17576180
Gizette Sperinde; Meire Bremer; Henry Maun; Amos Baruch; Bob Lazarus; JT Koerber; Rajesh Vij; Tangsheng Yi; Sally Fischer; Tracy Staton
Journal of Clinical Pharmacology, ISSN: 15524604 00912700
Divya Samineni; Hao Ding; Fang Ma; Rong Shi; Dan Lu; Dale Miles; Jialin Mao; Chunze Li; Jin Jin; Matthew Wright; Sandhya Girish; Yuan Chen
Inter-individual and inter-regional variations in enteric drug metabolizing enzyme activities: Results with cryopreserved human intestinal mucosal epithelia (CHIM) from the small intestines of 14 donors
Pharmacology Research and Perspectives,
Albert P. Li; Ming-Chih D Ho; Novera Alam; Walter Mitchell; Susan Wong; Zhengyin Yan; Jane Kenny; Cornelis E C A Hop
Organic Process Research and Development, ISSN: 1520586X 10836160
Nicholas A. White; Kyle Clagg; Lauren Sirois; Ngiap-Kie Lim; William A. Nack; Paul D. O'Shea; Haiming Zhang; Francis Gosselin
JCI insight, ISSN: 23793708
Kasia Owczarczyk; Matthew Cascino; Cecile Holweg; Wei Tew; Ward Ortmann; Timothy Behrens; Thomas Schindler; Langford; E. William St. Clair; Merkel; Spiera; Seo; Cees Gm Kallenberg; Specks; Noha Lim; John H. Stone; Paul Brunetta; Marco Prunotto
Conjugation Site Influences Antibody-Conjugated Drug PK Assays: Case Studies for Disulfide-Linked, Self-Immolating Next-Generation Antibody Drug Conjugates
Analytical Chemistry, ISSN: 00032700
Violet Lee; Surinder Kaur; Ola Saad
Systematic Variation of Pyrrolobenzodiazepine (PBD)-Dimer Payload Physicochemical Properties Impacts Efficacy and Tolerability of the Corresponding Antibody-Drug Conjugates
Journal of Medicinal Chemistry,
Leanna Staben; Jinhua Chen; Josefa Dela Cruz-Chuh; Geoff Del Rosario; Mary Ann Go; Jun Guo; S Cyrus Khojasteh; Kathy Kozak; Ginny Li; Carl Ng; Gail D. Lewis Phillips; Thomas Pillow; Rebecca K. Rowntree; John Wai; Binqing Wei; Keyang Xu; Zijin Xu; Shang-Fan Yu; Donglu Zhang; Peter Dragovich
Journal of Pharmaceutical and Biomedical Analysis, ISSN: 1873264X 07317085
Bingchuan Wei; Weitao Jia; Yi Yang; Mansour Jazayri; David Fulchiron; Justin Jeong; Qian Cai; Charlene Li; John Briggs; Milady Ninonuevo; Hongbin Liu; Zane Liu; Yonghua Taylor Zhang
Ectoine and Hydroxyectoine Stabilize Antibodies in Spray-Dried Formulations at Elevated Temperature and during a Freeze/Thaw Process
Molecular Pharmaceutics,
Purnendu K. Nayak; Meghan Goode; Debby Chang; Karthik Rajagopal
Ubiquitin Ligase COP1 Suppresses Neuroinflammation by Degrading c/EBPβ in Microglia
Cell, ISSN: 00928674
Ada Ndoja; Rohit Reja; Seung-Hye Lee; Webster; Hai Ngu; Christopher M. Rose; Don Kirkpatrick; Zora Modrusan; Ying-Jiun Jasmine Chen; Debbie Dugger; Vineela Gandham; Luke Xie; Kim Newton; Vishva Dixit
Journal of the American Society for Mass Spectrometry, ISSN: 18791123
Kristina Srzentić; Luca Fornelli; Yury O. Tsybin; Joseph A Loo; Henrique Seckler; Jeffrey N Agar; Lissa C. Anderson; Dina L. Bai; Alain Beck; Jennifer S. Brodbelt; Yuri E M van der Burgt; Julia Chamot-Rooke; Sneha Chatterjee; Yunqiu Chen; David J. Clarke; Paul O. Danis; Jolene K. Diedrich; Robert A. D'Ippolito; Mathieu Dupré; Natalia Gasilova; Ying Ge; Young Ah Goo; David R. Goodlett; Sylvester Greer; Kim F. Haselmann; Lidong He; Christopher L. Hendrickson; Joshua D. Hinkle; Matthew V. Holt; Sam Hughes; Donald F. Hunt; Neil L Kelleher; Anton N. Kozhinov; Ziqing Lin; Christian Malosse; Alan G. Marshall; Laure Menin; Robert J. Millikin; Konstantin O. Nagornov; Simone Nicolardi; Ljiljana Paša-Tolić; Stuart Pengelley; Neil R. Quebbemann; Anja Resemann; Wendy Sandoval; Richa Sarin; Nicholas D. Schmitt; Jeffrey Shabanowitz; Jared B. Shaw; Michael R. Shortreed; Lloyd M Smith; Frank Sobott; Detlev Suckau; Timothy Toby; Chad R. Weisbrod; Norelle C. Wildburger; John R. Yates; Sung Hwan Yoon; Nicolas L Young; Mowei
Journal of the American Society of Nephrology, ISSN: 15333450 10466673
Suzie Scales; Nidhi Gupta; Ann De Mazière; George Posthuma; Cecilia P. Chiu; Andrew A. Pierce; Kathy Hotzel; Jianhua Tao; Oded Foreman; Georgios Koukos; Francesca Oltrabella; Judith Klumperman; WeiYu Lin; Andy Peterson
Journal of the American Society of Nephrology, ISSN: 15333450 10466673
Nidhi Gupta; Grace Wang; Xiaohui Wen; Paul Moran; Maciej Paluch; Phil Hass; Amy Heidersbach; Benjamin Haley; Daniel Kirchhofer; Randall Brezski; Andy Peterson; Suzie Scales
Haematologica, ISSN: 15928721 03906078
Chris Bolen; Magdalena Klanova; Marek Trneny; Laurie H. Sehn; Jie He; Jing Tong; Joseph N. Paulson; Eugene Kim; Umberto Vitolo; Alice Di Rocco; Guenter Fingerle-Rowson; Tina Nielsen; Lenz; Mikkel Z. Oestergaard
Suppressing neutrophil-dependent angiogenesis abrogates resistance to anti-VEGF antibody in a genetic model of colorectal cancer
Proceedings of the National Academy of Sciences of the United States of America,
Yoshiro Itatani; Takamasa Yamamoto; Cuiling Zhong; Alfredo A. Molinolo; Jane Ruppel; Priti Hegde; M Mark Taketo; Napoleone Ferrara
Unstable mechanisms of resistance to inhibitors of escherichia coli lipoprotein signal peptidase
mBio, ISSN: 21612129
Homer Pantua; Elizabeth Skippington; Marie-Gabrielle Braun; Cameron Noland; Jingyu Diao; Yutian Peng; Susan Gloor; Donghong Yan; Jing Kang; Anand Kumar Katakam; Janina Reeder; Georgette Castanedo; Keira Garland; László Kömüves; Meredith Sagolla; Cary Austin; Jeremy Murray; Yiming Xu; Zora Modrusan; Min Xu; Emily Hanan; Sharookh Kapadia
PDA Journal of Pharmaceutical Science and Technology, ISSN: 19482124
Wen-Li Chung; Jian Yin; Steven Messick; Miguel Saggu; Kate Tschudi; Ann Marie Woys; Rod Rahimi; Marianne Azarias; Connie Kong; Bruce Kabakoff
Analytical Chemistry, ISSN: 15206882 00032700
Delia Li; Adam Farchone; Qing Zhu; Frank Macchi; Donald Walker; David Michels; Feng Yang
A Physiologically Based Pharmacokinetic Model of Vismodegib: Deconvoluting the Impact of Saturable Plasma Protein Binding, pH-Dependent Solubility and Nonsink Permeation
AAPS Journal,
Michael J. Dolton; Po-Chang Chiang; Fang Ma; Jin Y. Jin; Yuan Chen
Drug Metabolism and Disposition, ISSN: 1521009X 00909556
Teresa Mulder; Sudheer Bobba; Kevin Johnson; Jessica M. Grandner; Wei Wang; Chenghong Zhang; Jingwei Cai; Edna F. Choo; Cyrus Khojasteh; Donglu Zhang