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Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

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Cell Reports, ISSN: 22111247
Jesse E. Hanson; Keran Ma; Justin Elstrott; Martin Weber; Sandrine Saillet; Abdullah S. Khan; Jeffrey Simms; Benjamin Liu; Thomas A. Kim; Gui-Qiu Yu; Yelin Chen; Tzu-Ming Wang; Zhiyu Jiang; Bianca Liederer; Gauri Deshmukh; Hilda Solanoy; Connie Chan; Ben Sellers; Matthew Volgraf; Jacob Schwarz; David Hackos; Robby Weimer; Morgan Sheng; T. Michael Gill; Kimberly Scearce-Levie; Jorge J. Palop
ACS Medicinal Chemistry Letters, ISSN: 19485875
Matthew L. Landry; James Crawford
Chemico-Biological Interactions, ISSN: 18727786 00092797
Genualdi; Stuart C. Feinstein; Wilson; Jordan; Nicola Stagg
A Multicompany Assessment of Submicron Particle Levels by NTA and RMM in a Wide Range of Late-Phase Clinical and Commercial Biotechnology-Derived Protein Products
Journal of Pharmaceutical Sciences, ISSN: 00223549
Mario Hubert; Dennis T. Yang; Stanley C. Kwok; Anacelia Rios; Tapan K. Das; Ankit Patel; Klaus Wuchner; Valentyn Antochshuk; Friederike Junge; George M. Bou-Assaf; Shawn Cao; Miguel Saggu; Luis Montrond; Nataliya Afonina; Parag Kolhe; Vakhtang Loladze; Linda O. Narhi
Changes in Organic Anion Transporting Polypeptide Uptake in HEK293 Overexpressing Cells in the Presence and Absence of Human Plasma
Drug Metabolism and Disposition,
Christine M. Bowman; Eugene Chen; Liuxi Chen; Yi-Chen Chen; Xiaorong Liang; Matthew Wright; Yuan Chen; Jialin Mao
Clinical pharmacology of vc-MMAE antibody–drug conjugates in cancer patients: learning from eight first-in-human Phase 1 studies
mAbs, ISSN: 19420862
Chunze Li; Cindy Zhang; Zao Li; Divya Samineni; Dan Lu; Wang; Shang-Chiung Chen; Rong Zhang; Priya Agarwal; Bernard Fine; Sandhya Girish
Dissecting the molecular basis of high viscosity of monospecific and bispecific IgG antibodies
mAbs, ISSN: 19420862
Cholpon Tilegenova; Saeed Izadi; Peter Yin; Christine Huang; Jiansheng Wu; Diego Ellerman; Sarah Hymowitz; Benjamin Walters; Cleo Salisbury; Paul Carter
Harnessing MerTK agonism for targeted therapeutics
mAbs, ISSN: 19420862
Vivekananda Kedage; Diego Ellerman; Yongmei Chen; Wei-Ching Liang; Joven Borneo; Yan Wu; Minhong Yan
High-Resolution Characterization of ADCs by Orbitrap LCMS
Methods in Molecular Biology, ISSN: 10643745
Jintang He; Surinder Kaur; Keyang Xu
The role of integrins in the pathogenesis of inflammatory bowel disease: Approved and investigational anti-integrin therapies
Medicinal Research Reviews, ISSN: 01986325
Iris Dotan; Matthieu Allez; Silvio Danese; Mary Keir; Swati Tole; Jacqueline McBride
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Sreedhara Alavattam; Camellia Zamiri; Sirj Goswami; Sarah Weiser; Michael Cram; Twinkle R. Christian; Bharat Jagannathan
Trends in Neurosciences, ISSN: 1878108X 01662236
Brienne A. McKenzie; Vishva Dixit; Christopher Power
Urologic Oncology: Seminars and Original Investigations, ISSN: 18732496 10781439
Ahmad S. Halwani; Kelli M. Rasmussen; Vikas Patil; Catherine C. Li; Christina M. Yong; Zachary Burningham; Sumati Gupta; Sujata Narayanan; Wenny Lin; Susheela Carroll; Shivani K. Mhatre; Julie N. Graff; Robert Dreicer; Brian C. Sauer
Ophthalmology Retina, ISSN: 24686530
Glenn Yiu; R. Joel Welch; Yinwen Wang; Zhe Wang; Pin-wen Wang; Zdenka Haskova
Proprotein convertase 7 (PCSK7) reduces apoA-V levels
FEBS Journal, ISSN: 1742464X
Yahya Ashraf; Stéphanie Duval; Vatsal Sachan; Rachid Essalmani; Delia Susan-Resiga; Anna Roubtsova; Josée Hamelin; Gerhardy; Daniel Kirchhofer; Vincent S. Tagliabracci; Annik Prat; Robert Scott Kiss; Nabil G. Seidah
Cancer Research, ISSN: 15387445 00085472
Kenneth J. Finn; Scott Martin; Jeffrey Settleman
Atypical presentation and pathogenesis of a macaque lymphocryptoviral-associated B-cell lymphoma in a cynomolgus monkey
Veterinary Clinical Pathology, ISSN: 02756382
Adeyemi O. Adedeji; Vimala Vemireddi; Niraj K. Tripathi; Steffen Durinck; Jonathan M. Maher; Domagoj Vucic; Wendy Halpern
Clinical Ophthalmology, ISSN: 11775483 11775467
Praveen J. Patel; Focke Ziemssen; Eugene Ng; Anushini Muthutantri; David Silverman; Betsy Tschosik; Ronald Cantrell
Arthritis and Rheumatology, ISSN: 23265205 23265191
Jon T. Giles; Naveed Sattar; Sherine Gabriel; Paul M. Ridker; Steffen Gay; Charles Warne; David Musselman; Laura Brockwell; Emma Shittu; Micki Klearman; Thomas R. Fleming
Clinical Cancer Research, ISSN: 15573265 10780432
Antoni Ribas; Adil Daud; Anna Pavlick; Rene Gonzalez; Karl Lewis; Omid Hamid; Thomas F Gajewski; Igor Puzanov; Matthew Wongchenko; Isabelle Rooney; Jessie Hsu; Yibing Yan; Erica Park; McArthur
Journal of Medicinal Chemistry, ISSN: 15204804 00222623
Sayumi Yamazoe; Jeffrey Tom; Yue Fu; Wenqiong Wu; Liang Zeng; Changlei Sun; Qi Liu; Jie Lin; Kui Lin; Wayne Fairbrother; Steven Staben
Improved translation of stability for conjugated antibodies using an in vitro whole blood assay
mAbs,
Aimee Fourie-O'Donohue; Phillip Chu; Josefa Dela Cruz Chuh; Robert Tchelepi; Siao Ping Tsai; John C. Tran; William S. Sawyer; Dian Su; Carl Ng; Keyang Xu; Shang-Fan Yu; Thomas Pillow; Jack D. Sadowsky; Peter Dragovich; Yichin Liu; Kathy Kozak
Methods in Pharmacology and Toxicology, ISSN: 19406053 15572153
Jinze Li; Mayur S. Mitra; Gautham Rao
Clinical Breast Cancer, ISSN: 19380666 15268209
José Bines; Marion Procter; Eleonora Restuccia; Viale; Zardavas; Suter; Amal Arahmani; Veerle Van Dooren; Baselga; Emma Clark; Jennifer Eng-Wong; Richard D. Gelber; Martine Piccart; Volker Mobus; Evandro De Azambuja
Nature Structural and Molecular Biology, ISSN: 15459985 15459993
Nicholas P. D. Liau; Timothy J. Wendorff; John Quinn; Micah Steffek; Wilson Phung; Peter Liu; Jia Tang; Flaviyan J. Irudayanathan; Saeed Izadi; Andrey S. Shaw; Shiva Malek; Sarah Hymowitz; Sudhamsu Sudhamsu
Methods in Molecular Biology, ISSN: 19406029 10643745
Yilma Adem
Journal of Clinical Oncology, ISSN: 15277755 0732183X
Laurie H. Sehn; Alex F. Herrera; Christopher R. Flowers; Manali K. Kamdar; Andrew McMillan; Mark Hertzberg; Sarit E. Assouline; Tae Min Kim; Won Seog Kim; Muhit Ozcan; Jamie Hirata; Elicia Penuel; Joseph N. Paulson; Ji Cheng; Grace Ku; Matthew Matasar
Molecular Cancer Therapeutics, ISSN: 15388514 15357163
Heather M. Moore; Heidi Savage; Carol O'Brien; Wei Zhou; Ethan S. Sokol; Michael E. Goldberg; Ciara Metcalfe; Lori Friedman; Mark Lackner; Tim Wilson
Analytical Chemistry, ISSN: 15206882 00032700
Peilu Liu; Xuan Gao; Victor Lundin; Catherine Shi; Yilma Adem; Kevin Lin; Guoying Jiang; Yung-Hsiang Kao; Feng Yang; David Michels; Alan G. Marshall; Hui-Min Zhang
Annals of Oncology, ISSN: 15698041 09237534
Paolo A. Ascierto; Karl Lewis; Anna Maria Di Giacomo; Lev Demidov; Mario Mandala; Igor Bondarenko; Christopher Herbert; Andrzej Mackiewicz; Piotr Rutkowski; Alexander Guminski; Brian Simmons; Ye; Gregory Hooper; Matthew Wongchenko; Grant Goodman; Yibing Yan; Dirk Schadendorf
RIP1 kinase activity is critical for skin inflammation but not for viral propagation
Journal of Leukocyte Biology, ISSN: 07415400
Webster; Youngsu Kwon; Summer Park; Hua Zhang; Nick Corr; Nina Ljumanovic; Adeyemi O. Adedeji; Eugene Varfolomeev; Tanya Goncharov; Jessica Preston; Sara F. Santagostino; Snahel Patel; Min Xu; Jonathan M. Maher; Brent McKenzie; Domagoj Vucic
Survey of Customers Requesting Medical Information: Preferences and Information Needs of Patients and Health Care Professionals to Support Treatment Decisions
Therapeutic Innovation and Regulatory Science,
Stacey Fung; Cheryl Sud; Matt Suchodolski
Nature Genetics, ISSN: 15461718 10614036
Kushal Suryamohan; Sajesh P. Krishnankutty; Joe Guillory; Matthew Jevit; Markus S. Schröder; Meng Wu; Boney Kuriakose; Oommen K. Mathew; Rajadurai C. Perumal; Ivan Koludarov; Leonard Goldstein; Kate Senger; Mandumpala Davis Dixon; Dinesh Velayutham; Derek Vargas; Subhra Chaudhuri; Megha Muraleedharan; Ridhi Goel; Jasmine Chen; Aakrosh Ratan; Peter Liu; Brendan Faherty; Guillermo de la Rosa; Hiroki Shibata; Miriam Baca; Meredith Sagolla; James Ziai; Gus A. Wright; Domagoj Vucic; Sangeetha Mohan; Aju Antony; Jeremy Stinson; Donald S. Kirkpatrick; Rami Hannoush; Steffen Durinck; Zora Modrusan; Eric Stawiski; Kristen Wiley; Terje Raudsepp; R. Manjunatha Kini; Arun Zachariah; Somasekar Seshagiri
Annual Review of Physiology, ISSN: 15451585 00664278
Heinrich Jasper
Antitumor activity of ipatasertib combined with chemotherapy: results from a phase Ib study in solid tumors
Annals of Oncology, ISSN: 09237534
Isakoff; Tabernero; Molife; Jean-Charles Soria; Andrés Cervantes; Nicholas J. Vogelzang; Manish R. Patel; Hussain; Ari Baron; Guillem Argiles; Paul Conkling; Deepak Sampath; Daniel Maslyar; Premal Patel; Wai Y. Chan; Steven Gendreau; Luna Musib; Na Xu; Han Ma; Kui Lin; Bendell
Biotechnology Progress, ISSN: 15206033 87567938
Bin Yang; Hua Wang; Kimberly Kaleas; Michelle Butler; Jayme Franklin; Amber Bill; Sally A. Baylis; Qi Chen; Johannes Blümel
Journal of Allergy and Clinical Immunology: In Practice, ISSN: 22132198
Nicola A. Hanania; Ratko Djukanovic; Liam G Heaney; Ming Yang; Bongin Yoo; Ahmar Iqbal; Noelle Griffin; Bradley E. Chipps
CPT: Pharmacometrics and Systems Pharmacology, ISSN: 21638306
Iraj Hosseini; Justin Feigelman; Anita Gajjala; Monica Susilo; Vidya Ramakrishnan; Saroja Ramanujan; Kapil Gadkar
Biotechnology Progress, ISSN: 15206033 87567938
Joe Carver; Domingos Ng; Michelle Zhou; Peggy Ko; Dejin Zhan; Mandy Yim; David Shaw; Brad Snedecor; Mike Laird; Steven E. Lang; Amy Shen; Zhilan Hu
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Jannatun Nayem; Zhenhuan Zhang; Anthony Tomlinson; Isidro (Dan) Zarraga; Norman J. Wagner; Yun Liu
Lab on a Chip - Miniaturisation for Chemistry and Biology, ISSN: 14730189 14730197
Stephen Fowler; Wen Li Kelly Chen; David B. Duignan; Anshul Gupta; Niresh Hariparsad; Jane Kenny; W. George Lai; Jennifer Liras; Jonathan A. Phillips; Jinping Gan
eLife, ISSN: 2050084X
Mable Lam; Scot Marsters; Avi Ashkenazi; Peter Walter
Modulation of Notch1 signaling regulates bone fracture healing
Journal of Orthopaedic Research, ISSN: 07360266
Sanja Novak; Emilie Roeder; Benjamin P. Sinder; Douglas J. Adams; Chris Siebel; Danka Grcevic; Kurt D. Hankenson; Brya G. Matthews; Ivo Kalajzic
Monitoring protein communities and their responses to therapeutics
Nature Reviews Drug Discovery, ISSN: 14741776
Hanna G. Budayeva; Don Kirkpatrick
Ophthalmology, ISSN: 15494713 01616420
Nancy M. Holekamp; Charles C. Wykoff; Steffen Schmitz-Valckenberg; Jordi Monés; Eric H. Souied; Hugh Lin; Melvin D. Rabena; Ronald Cantrell; Erin Henry; Fan Tang; Balakumar Swaminathan; Jillian Martin; Daniela Ferrara; Giovanni Staurenghi
NRF2 activates growth factor genes and downstream AKT signaling to induce mouse and human hepatomegaly
Journal of Hepatology, ISSN: 01688278
Feng He; Laura Antonucci; Shinichiro Yamachika; Zechuan Zhang; Koji Taniguchi; Atsushi Umemura; Georgia Hatzivassiliou; Meron Roose-Girma; Miguel Reina-Campos; Angeles Duran; Maria T. Diaz-Meco; Jorge Moscat; Beicheng Sun; Michael Karin
Preclinical Safety Assessment of a Highly Selective and Potent Dual Small-Molecule Inhibitor of CBP/P300 in Rats and Dogs
Toxicologic Pathology, ISSN: 01926233
Paula Katavolos; Cain; Cindy A. Farman; Anthony Romero; Steven Magnuson; Justin Ly; Edna Choo; Anand Kumar Katakam; Roxanne Andaya; Jonathan M. Maher
Ophthalmology Retina, ISSN: 24686530
Usha Chakravarthy; Clare C. Bailey; Peter H. Scanlon; Martin McKibbin; Rehna S. Khan; Sajjad Mahmood; Louise Downey; Narendra Dhingra; Christopher Brand; Christopher Brittain; Jeffrey R. Willis; Alessandra Venerus; Anushini Muthutantri; Ronald Cantrell
Nature Structural and Molecular Biology, ISSN: 15459985 15459993
Annette M. Vogl; Lilian Phu; Raquel Becerra; Sebastian A. Giusti; Erik Verschueren; Trent Hinkle; Martín D. Bordenave; Max Adrian; Amy Heidersbach; Patricio Yankilevich; Fernando D. Stefani; Wolfgang Wurst; Casper C Hoogenraad; Don Kirkpatrick; Damian Refojo; Morgan Sheng
Reproducible quantification of IgG uptake at endogenous and overexpressed FcRn levels at pH 7.4: Comparison of a wild type IgG and a stronger FcRn binding variant
Journal of Immunological Methods, ISSN: 00221759
Jianhuan Zhang; Jean-Michel Vernes; Xiaohui Wen; Ernest Oh; Suzie Scales; Y Gloria Meng