Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 51 - 100 OF 11054 RESULTS

Effect of Microenvironmental pH Modulation on the Dissolution Rate and Oral Absorption of the Salt of a Weak Acid – Case Study of GDC-0810
Pharmaceutical Research, ISSN: 07248741
Hao Helen Hou; Wei Jia; Lichuan Liu; Sravanthi Cheeti; Jane Li; Ewa Nauka; Karthik Nagapudi
Microglia in Alzheimer's disease
Journal of Cell Biology, ISSN: 00219525
David Hansen; Jesse Hanson; Morgan Sheng
Safety and efficacy of subcutaneous tocilizumab in systemic sclerosis: Results from the open-label period of a phase II randomised controlled trial (faSScinate)
Annals of the Rheumatic Diseases, ISSN: 00034967
Dinesh Khanna; Christopher P. Denton; Celia J.F. Lin; Jacob M. van Laar; Tracy M. Frech; Marina E. Anderson; Murray Baron; Lorinda Chung; Gerhard Fierlbeck; Santhanam Lakshminarayanan; Yannick Allanore; Janet E. Pope; Gabriela Riemekasten; Virginia D. Steen; Ulf Müller-Ladner; Helen Spotswood; Laura Burke; Jeffrey Siegel; Angelika Jahreis; Daniel E. Furst
SUV420H2 is an epigenetic regulator of epithelial/ mesenchymal states in pancreatic cancer
Journal of Cell Biology, ISSN: 00219525
Manuel Viotti; Catherine Wilson; Mark McCleland; Hartmut Koeppen; Benjamin Haley; Suchit Jhunjhunwala; Christiaan Klijn; Zora Modrusan; David Arnott; Marie Classon; Daniel Stephan; Ira Mellman
Drug Metabolism and Disposition, ISSN: 1521009X 00909556
Sarah Billington; Adrian S. Ray; Laurent Salphati; Guangqing Xiao; Xiaoyan Chu; William Griffith Humphreys; Mingxiang Liao; Caroline A. Lee; Anita Mathias; Marcel Hop; Christopher Rowbottom; Raymond Evers; Yurong Lai; Edward J. Kelly; Bhagwat Prasad; Jashvant D. Unadkat
International Journal of Pharmaceutics, ISSN: 18733476 03785173
Raj Mukherjee; Chen Mao; Sayantan Chattoraj; Bodhisattwa Chaudhuri
Journal of Pharmaceutical and Biomedical Analysis, ISSN: 1873264X 07317085
Marie-France Morissette; Larry Wigman; Jerry Tso
HER2 is not a cancer subtype but rather a pan-cancer event and is highly enriched in AR-driven breast tumors
Breast Cancer Research, ISSN: 14655411
Anneleen Daemen; Gerard Manning
Mechanism-specific assay design facilitates the discovery of Nav1.7-selective inhibitors
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Tania Chernov-Rogan; Tianbo Li; Gang Lu; Henry Verschoof; Kuldip Khakh; Steven W Jones; Maureen Beresini; Chang Liu; Dan Ortwine; Steven J. McKerrall; David Hackos; Dan Sutherlin; Charles J. Cohen; Jun Chen
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
Cell Death and Differentiation, ISSN: 13509047
Galluzzi; Vitale; Aaronson; Abrams; Dieter Adam; Patrizia Agostinis; Alnemri; Altucci; Ivano Amelio; Andrews; Margherita Annicchiarico-Petruzzelli; Antonov; Eli Arama; Eric H. Baehrecke; Barlev; Bazan; Francesca Bernassola; Bertrand; Bianchi; Blagosklonny; Blomgren; Borner; Patricia Boya; Catherine Brenner; Michelangelo Campanella; Eleonora Candi; Didac Carmona-Gutierrez; Francesco Cecconi; Chan; Navdeep S. Chandel; Cheng; Chipuk; Cidlowski; Ciechanover; Cohen; Marcus Conrad; Cubillos-Ruiz; Czabotar; Vincenzo D’Angiolella; Dawson; Dawson; De Laurenzi; De Maria; Debatin; DeBerardinis; Mohanish Deshmukh; Di Daniele; Francesco Di Virgilio; Dixit; Dixon; Duckett; Dynlacht; Wafik S. El-Deiry; Elrod; Gian Maria Fimia; Fulda; García-Sáez; Abhishek D. Garg; Carmen Garrido; Evripidis Gavathiotis; Pierre Golstein; Eyal Gottlieb; Green; Greene; Gronemeyer; Atan Gross; Hajnoczky; Hardwick; Harris; Hengartner; Claudio Hetz; Hidenori Ichijo; Marja Jäättelä; Bertrand Joseph
Nature Immunology, ISSN: 15292916 15292908
Mohammad Samie; Junghyun Lim; Erik Verschueren; Joshua Baughman; Ivan Peng; Aaron Wong; Youngsu Kwon; Yasin Senbabaoglu; Jason Hackney; Mary Keir; Brent McKenzie; Don Kirkpatrick; Menno van Lookeren Campagne; Aditya Murthy
Journal of Clinical Oncology, ISSN: 15277755 0732183X
Manish A. Shah; Luis A. Herráez-Baranda; Amit Garg; Josep Tabernero
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 10916490 00278424
Barbara Piasecka; Darragh Duffy; Alejandra Urrutia; Hélène Quach; Etienne Patin; Céline Posseme; Jacob Bergstedt; Bruno Charbit; Vincent Rouilly; Cameron R. MacPherson; Milena Hasan; Benoit Albaud; David Gentien; Jacques Fellay; Matthew Albert; Lluis Quintana-Murci
Langmuir, ISSN: 15205827 07437463
Aadithya Kannan; Ian Shieh; Danielle L. Leiske; Gerald G. Fuller
Development of a PD-L1 Complementary Diagnostic Immunohistochemistry Assay (SP142) for Atezolizumab
Applied Immunohistochemistry and Molecular Morphology, ISSN: 15412016
Bharathi Vennapusa; Brian Baker; Marcin Kowanetz; Jennifer Boone; Ina Menzl; Jean-Marie Bruey; Gregg Fine; Sanjeev Mariathasan; Ian McCaffery; Simonetta Mocci; Sandra Rost; Dustin Smith; Eslie Dennis; Szu-Yu Tang; Bita Damadzadeh; Espen Walker; Priti Hegde; Williams; Hartmut Koeppen; Zachary Boyd
Diverse Brain Myeloid Expression Profiles Reveal Distinct Microglial Activation States and Aspects of Alzheimer's Disease Not Evident in Mouse Models
Cell Reports,
Brad Friedman; Karpagam Srinivasan; Gai Ayalon; Bill Meilandt; Han Lin; Melanie Huntley; Yi Cao; Seung-Hye Lee; Patrick Haddick; Hai Ngu; Zora Modrusan; Jessica L. Larson; Josh Kaminker; Marcel van der Brug; David Hansen
Adherence to the American Diabetes Association retinal screening guidelines for population with diabetes in the United States
Ophthalmic Epidemiology, ISSN: 09286586
JaeJin An; Fang Niu; Adam Turpcu; Yamina Rajput; T Craig Cheetham
Journal of Pharmacokinetics and Pharmacodynamics, ISSN: 15738744 1567567X
Iraj Hosseini; Anita Gajjala; Daniela Bumbaca Yadav; Sid Sukumaran; Saroja Ramanujan; Ricardo Paxson; Kapil Gadkar
Selectively Modulating Conformational States of USP7 Catalytic Domain for Activation
Structure, ISSN: 09692126
Ayşegül Özen; Lionel Rouge; Charlene Bashore; Brian R. Hearn; Nicholas Skelton; Erin Dueber
Molecular Pharmaceutics, ISSN: 15438392 15438384
Balakrishnan S. Moorthy; Isidro (Dan) Zarraga; Lokesh Kumar; Ben Walters; Pierre Goldbach; Elizabeth M. Topp; Andrea Allmendinger
Safety testing of monoclonal antibodies in non-human primates: Case studies highlighting their impact on human risk assessment
mAbs, ISSN: 19420862
Frank R. Brennan; Joy A. Cavagnaro; Kathleen McKeever; Patricia C. Ryan; Melissa Schutten; John Vahle; Gerhard F. Weinbauer; Estelle Marrer-Berger; Lauren E. Black
AAPS Journal, ISSN: 15507416
Allison Given Chunyk; Alison Joyce; Sally Fischer; Mark Dysinger; Alvydas Mikulskis; Andreas Jeromin; Rosemary Lawrence-Henderson; Dana Baker; David Yeung
Methods in Molecular Biology, ISSN: 10643745
Dan Ortwine
Bioorganic and Medicinal Chemistry Letters, ISSN: 14643405 0960894X
Kwong Wah Lai; Anthony Romero; Vickie Tsui; Maureen Beresini; Gladys Boenig; Sarah M. Bronner; Kevin Chen; Zhongguo Chen; Edna Choo; Terry Crawford; Patrick Cyr; Susan Kaufman; Yingjie Li; Jiangpeng Liao; Wenfeng Liu; Justin Ly; Jeremy Murray; Weichao Shen; John Wai; Fei Wang; Caicai Zhu; Xiaoyu Zhu; Steven Magnuson
Respiratory Medicine, ISSN: 15323064 09546111
Phillip Korenblat; Edwin Kerwin; Igor Leshchenko; Karl Yen; Cecile Holweg; Judith Anzures-Cabrera; Carmen Martin; Wendy Putnam; Laura Governale; Julie Olsson; John Matthews
Toxicology and Applied Pharmacology, ISSN: 10960333 0041008X
Steven Cepa; David M. Potter; Lisa Wong; Leah Schutt; Jacqueline Tarrant; Jodie Pang; Xiaolin Zhang; Roxanne Andaya; Laurent Salphati; Yingqing Ran; Le An; Ryan Morgan; Jonathan M. Maher
Veterinary Pathology, ISSN: 15442217 03009858
Lauri Diehl; David K. Meyerholz; Michael J. Day; Verena K. Affolter
Patient acceptable symptom state in scleroderma: results from the tocilizumab compared with placebo trial in active diffuse cutaneous systemic sclerosis
Rheumatology,
Michael B. Arnold; Dinesh Khanna; Christopher P. Denton; Jacob M. van Laar; Tracy M. Frech; Marina E. Anderson; Murray Baron; Lorinda Chung; Gerhard Fierlbeck; Santhanam Lakshminarayanan; Yannick Allanore; Gabriela Riemekasten; Virginia D. Steen; Ulf Müller-Ladner; Helen Spotswood; Laura Burke; Jeffrey Siegel; Angelika Jahreis; Daniel E. Furst; Janet E. Pope
Reply to hunsberger and memoli, "efficacy analysis in healthy-volunteer influenza challenge trials: Intention to treat"
Antimicrobial Agents and Chemotherapy, ISSN: 00664804
Jacqueline McBride; Jeremy Lim; Tracy Burgess; Rong Deng; Michael Derby; Mauricio Maia; Priscilla Horn; Omer Siddiqui; Daniel Sheinson; Haiyin Chen; Elizabeth Newton; Dimitri Fillos; Denise Nazzal; Carrie Rosenberger; Maikke Ohlson; Rob Lambkin-Williams; Hosnieh Fathi; Jeff Harris; Jorge A. Tavela
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Linda Bao; Le An; Yingqing Ran
Cell Chemical Biology, ISSN: 24519448 24519456
Xinxin Gao; Rami Hannoush
Trials, ISSN: 17456215
Catherine E. Hanratty; John Matthews; Joe Arron; David Choy; Ian D. Pavord; Peter Bradding; Chris E. Brightling; Rekha Chaudhuri; Douglas Cowan; Ratko Djukanovic; Nicola Gallagher; Stephen J. Fowler; Tim Hardman; Timothy Harrison; Cecile Holweg; Peter Howarth; James Lordan; Adel Mansur; Andrew Menzies-Gow; Sofia Mosesova; Robert Niven; Douglas S. Robinson; Dominick E. Shaw; Samantha Walker; Ashley Woodcock; Liam G. Heaney; Ian Adcock; Boriello; Matthew Catley; Chung; Richard W. Costello; Sebastian Johnston; Frank Keane; May; Lisa Pierre; Dirk Smith; Chris Stevenson; Val Hudson; David Supple; Gainsborough; Horn
Journal of Allergy and Clinical Immunology, ISSN: 10976825 00916749
Salman Siddiqui; Aarti Shikotra; Matthew Richardson; Emma Doran; David Choy; Alex Bell; Cary Austin; Jeff Eastham Anderson; Beverley Hargadon; Joe Arron; Andrew J. Wardlaw; Chris E. Brightling; Liam G. Heaney; Peter Bradding
Conjugation of Indoles to Antibodies through a Novel Self-Immolating Linker
Chemistry - A European Journal, ISSN: 09476539
Peter Dragovich; Robert Blake; Chunjiao Chen; Jinhua Chen; Josefa Chuh; Willem denBesten; Fang Fan; Aimee Fourie-O'Donohue; Steven J. Hartman; Changrong He; Jintang He; Ellen Ingalla; Kathy Kozak; Steve Leong; Jiawei Lu; Yong Ma; Lingyao Meng; Michelle Nannini; Jason Oeh; Rachana Ohri; Gail LewisPhillips; Thomas Pillow; Rebecca K. Rowntree; Deepak Sampath; Dick Vandlen; Breanna S. Vollmar; John Wai; Ingrid Wertz; Keyang Xu; Zijin Xu; Donglu Zhang
Journal of the American Academy of Dermatology, ISSN: 10976787 01909622
Eric L. Simpson; Carsten Flohr; Lawrence F. Eichenfield; Thomas Bieber; Howard Sofen; Alain Taïeb; Ryan Owen; Wendy Putnam; Marcela Castro; Kendra DeBusk; Chin-Yu Lin; Athina Voulgari; Karl Yen; Ted Omachi
Oncotarget, ISSN: 19492553
John C. Byrd; Stephen Smith; Nina D. Wagner-Johnston; Jeff P. Sharman; Chen; Ranjana H. Advani; Bradley Augustson; Paula Marlton; S. Renee Commerford; Kwame Okrah; Lichuan Liu; Elaine Murray; Elicia Penuel; Ashley F. Ward; Ian W. Flinn
Immune-modified response evaluation criteria in solid tumors (imrecist): Refining guidelines to assess the clinical benefit of cancer immunotherapy
Journal of Clinical Oncology, ISSN: 0732183X
Stephen Hodi; Marcus Ballinger; Benjamin Lyons; Jean-Charles Soria; Mizuki Nishino; Tabernero; Thomas Powles; David Smith; Axel Hoos; Chris McKenna; Ulrich Beyer; Ina Rhee; Gregg Fine; Nathan Winslow; Daniel Chen; Jedd D Wolchok
Ophthalmology, ISSN: 15494713 01616420
Srinivas Sadda; Lisa Tuomi; Beiying Ding; Anne E. Fung; Jill Hopkins
Journal of Ocular Pharmacology and Therapeutics, ISSN: 15577732 10807683
Vladimir Bantseev; Rebecca Erickson; Douglas Leipold; Caroline Amaya; Paul E. Miller; Helen Booler; Evan Thackaberry
Pathogen clearance and immune adherence “revisited”: Immuno-regulatory roles for CRIg
Seminars in Immunology, ISSN: 10445323
Menno van Lookeren Campagne; Admar Verschoor
CPT: Pharmacometrics and Systems Pharmacology, ISSN: 21638306
Jialin Mao; Utkarsh Doshi; Matthew Wright; Marcel Hop; Albert P. Li; Yuan Chen
Safety, Pharmacokinetics, and Pharmacodynamics in Healthy Volunteers Treated With GDC-0853, a Selective Reversible Bruton's Tyrosine Kinase Inhibitor
Clinical Pharmacology and Therapeutics, ISSN: 00099236
Ann E. Herman; Leslie Chinn; Shweta G. Kotwal; Elaine Murray; Rui Zhao; Marilyn Florero; Alyse Lin; Anita Moein; Rena Wang; Meire Bremer; Serika Kokubu; Adrian Serone; Eva L. Hanze; Anders Viberg; Alyssa Morimoto; Helen Winter; Tamiko R. Katsumoto
EMBO Reports, ISSN: 14693178 1469221X
Dan Du; Yoko Katsuno; Dominique Meyer; Erine H Budi; Si-Han Chen; Hartmut Koeppen; Hongjun Wang; Rosemary J Akhurst; Rik Derynck
Status and future of 3D cell culture in toxicity testing
Methods in Pharmacology and Toxicology, ISSN: 15572153
Monicah A. Otieno; Jinping Gan; Will Proctor
Toxicologic Pathology, ISSN: 15331601 01926233
Kenneth A. Schafer; John Eighmy; James D. Fikes; Wendy Halpern; Renee R. Hukkanen; Gerald G. Long; Emily K. Meseck; Daniel J. Patrick; Michael S. Thibodeau; Charles E. Wood; Sabine Francke
Clinical and Translational Science, ISSN: 17528062 17528054
Greg Ferl; Art Reyes; Laura Sun; Melissa Cheu; Amy Oldendorp; Saroja Ramanujan; Eric Stefanich
A solid-phase approach for the synthesis of α-Aminoboronic acid peptides
RSC Advances,
Blake Daniels; Craig Stivala
Journal of Immunological Methods, ISSN: 18727905 00221759
Yongmei Chen; Si Hyun Kim; Yonglei Shang; Joe Guillory; Jeremy Stinson; Qing Zhang; Isidro Hotzel; Kam Hon Hoi
Biotechnology Progress, ISSN: 15206033 87567938
Glen Giese; Ambrose Williams; Maricel Rodriguez; Josefine Persson
Pediatric Blood and Cancer, ISSN: 15455017 15455009
Julia C. Chisholm; Jozef Suvada; Ira J. Dunkel; Michela Casanova; Weijiang Zhang; Natasha Ritchie; YJ Choi; Jane Park; Meghna Das Thakur; Stephen Simko; Nga Wan Rachel Tam; Andrea Ferrari