Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 10151 - 10200 OF 15805 RESULTS

Accounting for Interim Analyses in the Assessment of Program Expected Net Present Value
Therapeutic Innovation and Regulatory Science, ISSN: 21684790
Lee D. Kaiser; Jeffrey D. Helterbrand; Hal V. Barron
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Quantification of viable tumor microvascular characteristics by multispectral analysis
Magnetic Resonance in Medicine, ISSN: 15222594 07403194
Berry; Kai H. Barck; MaryAnn Go; Ross; Xiumin Wu; Simon P. Williams; Alvin Gogineni; Mary J. Cole; Nicholas Van Bruggen; Fuh; Franklin V. Peale Jr.; Napoleone Ferrara; Ross; Ralph H. Schwall; Richard A. D. Carano
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Improved health-related quality of life for patients with active rheumatoid arthritis receiving rituximab - Results of the dose-ranging assessment: International clinical evaluation of rituximab in rheumatoid arthritis (DANCER) trial
Journal of Rheumatology, ISSN: 0315162X
Philip J. Mease; Dennis A. Revicki; Jacek Szechinski; Maria Greenwald; Alan Kivitz; Leonor Barile-Fabris; Jatinderpal Kalsi; Jennifer Eames; Marjatta Leirisalo-Repo
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The effects of CYP3A4 inhibition on erlotinib pharmacokinetics: Computer-based simulation (SimCYP™) predicts in vivo metabolic inhibition
European Journal of Clinical Pharmacology, ISSN: 00316970
Ashok Rakhit; Michael P. Pantze; Scott Fettner; Hannah M. Jones; Jean-Eric Charoin; Myriam Riek; Bert L. Lum; Marta Hamilton
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In reply
Annals of Emergency Medicine, ISSN: 01960644
Andrew R. Erdman
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hADA2a and hADA3 are required for acetylation, transcriptional activity and proliferative effects of β-catenin
Cancer Biology and Therapy, ISSN: 15384047 15558576
Min Yang; Marian L. Waterman; Rainer Brachmann
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Subspecialty differences in asthma characteristics and management
Mayo Clinic Proceedings, ISSN: 00256196
Hubert Chen; Charles A. Johnson; Tmirah Haselkorn; June H. Lee; Elliot Israel
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Characterization of a complex glycoprotein whose variable metabolic clearance in humans is dependent on terminal N-acetylglucosamine content
Biologicals, ISSN: 10451056 10958320
Rodney Keck; Namita Nayak; Laura Lerner; Shanta Raju; Stacey Ma; Thomas Schreitmueller; Steven M. Chamow; Kathy Moorhouse; Claire Kotts; Andrew J.S. Jones
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Blocking vascular endothelial growth factor-A inhibits the growth of pituitary adenomas and lowers serum prolactin level in a mouse model of multiple endocrine neoplasia type 1
Clinical Cancer Research, ISSN: 10780432
Nina Korsisaari; Ross; Xiumin Wu; Marcin Kowanetz; Navneet Pal; Linda Hall; Jeffrey Eastham-Anderson; William F. Forrest; Nicholas Van Bruggen; Franklin V. Peale Jr.; Napoleone Ferrara
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Recommended changes to oncology clinical trial design: Revolution or evolution?
European Journal of Cancer, ISSN: 09598049
Ratain; Rachel W. Humphrey; Gary Gordon; Gwendolyn Fyfe; Peter C. Adamson; Thomas R. Fleming; Walter M. Stadler; Donald A. Berry; Carl C. Peck
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High CD21 expression inhibits internalization of anti-CD19 antibodies and cytotoxicity of an anti-CD19-drug conjugate
British Journal of Haematology, ISSN: 00071048 13652141
Gladys S. Ingle; Pamela Chan; J. Michael Elliott; Wesley S. Chang; Koeppen; Jean-Philippe Stephan; Suzie J. Scales
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Computational approaches for predicting causal missense mutations in cancer genome projects
Current Bioinformatics, ISSN: 15748936
Lawrence S. Hon; Joshua S. Kaminker; Zemin Zhang
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Polymorphism at the TNF superfamily gene TNFSF4 confers susceptibility to systemic lupus erythematosus
Nature Genetics, ISSN: 10614036 15461718
Deborah S. Cunninghame Graham; Robert R. Graham; Harinder Manku; Andrew K. Wong; John C. Whittaker; Patrick M. Gaffney; Kathy L. Moser; John D. Rioux; David Altshuler; Timothy W. Behrens; Timothy J. Vyse
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Genome wide screens in yeast to identify potential binding sites and target genes of DNA-binding proteins
Nucleic Acids Research, ISSN: 03051048 13624962
Jue Zeng; Jizhou Yan; Ting Wang; Deborah Mosbrook-Davis; Kyle T. Dolan; Ryan Christensen; Gary D. Stormo; David Haussler; Richard H. Lathrop; Rainer Brachmann; Shawn M. Burgess
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In vivo imaging of mucosal CD4+ T cells using single photon emission computed tomography in a murine model of colitis
Journal of Immunological Methods, ISSN: 00221759
Bittoo Kanwar; Dong Wei Gao; Andrew B. Hwang; James P. Grenert; Simon P. Williams; Benjamin Franc; Joseph M. McCune
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Ongoing sonic hedgehog signaling is required for dorsal midline formation in the developing forebrain
Developmental Neurobiology, ISSN: 19328451 1932846X
Monica Hayhurst; Bryan B. Gore; Marc Tessier-Lavigne; Susan K. McConnell
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Coordination of growth rate, cell cycle, stress response, and metabolic activity in yeast
Molecular Biology of the Cell, ISSN: 10591524
Matthew J. Brauer; Curtis Huttenhower; Edoardo M. Airoldi; Rachel Rosenstein; John C. Matese; David Gresham; Viktor M. Boer; Olga G. Troyanskaya; David Botstein
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Optimization approaches in the routine analysis of monoclonal antibodies by capillary electrophoresis
LC-GC Europe, ISSN: 14716577
Oscar Salas-Solano; Lynn Gennaro; Chantal Felten
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The proteasome inhibitor bortezomib in combination with gemcitabine and carboplatin in advanced non-small cell lung cancer: A California Cancer Consortium phase I study
Journal of Thoracic Oncology, ISSN: 15561380 15560864
Angela M. Davies; Christopher Ruel; Primo N. Lara; Derick H. Lau; Paul H. Gumerlock; Richard Bold; Stephen Shibata; Heinz-Josef Lenz; David P. Schenkein; David R. Gandara
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The business case for energy management in high-tech industries
Energy Efficiency, ISSN: 1570646X 15706478
Evan Mills; Gary Shamshoian; Michele Blazek; Phil Naughton; Robert S. Seese; William Tschudi; Dale Sartor
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Comparison of two approaches for handling missing covariates in logistic regression
Educational and Psychological Measurement, ISSN: 15523888 00131644
Chao-Ying Joanne Peng; Jin Zhu
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Randomized, Double-Masked, Sham-Controlled Trial of Ranibizumab for Neovascular Age-related Macular Degeneration: PIER Study Year 1
American Journal of Ophthalmology, ISSN: 00029394
Carl D. Regillo; David M. Brown; Prema Abraham; Huibin Yue; Tsontcho Ianchulev; Susan Schneider; Naveed Shams
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Personalized medicine complicates medical decision-making
Managed Care, ISSN: 10623388
Thomas Morrow
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Height velocity targets from the national cooperative growth study for first-year growth hormone responses in short children
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X 0021972X
Bert Bakker; James W. Frane; Henry Anhalt; Barbara M. Lippe; Rosenfeld
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Long-term safety of recombinant human growth hormone in Turner syndrome
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X 0021972X
Katrina Bolar; Andrew R. Hoffman; Thomas J. Maneatis; Barbara M. Lippe
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T-cell lymphomas in T-cell-specific Pten-deficient mice originate in the thymus
Leukemia, ISSN: 14765551 08876924
Thijs Hagenbeek; Hergen Spits
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Recently-approved sapropterin reduces phenylalanine levels
Managed Care, ISSN: 10623388
Thomas Morrow
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Compliance and persistence in pediatric and adult patients receiving growth hormone therapy
Endocrine Practice, ISSN: 1530891X
Rosenfeld; Bert Bakker
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Assessing productivity loss and activity impairment in severe or difficult-to-treat asthma
Value in Health, ISSN: 15244733 10983015
Hubert Chen; Paul D. Blanc; Mary Lou Hayden; Eugene R. Bleecker; Chawla; June H. Lee
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Insurance status and asthma-related health care utilization in patients with severe asthma
Annals of Allergy, Asthma and Immunology, ISSN: 10811206
Anju T. Peters; Julie C. Klemens; Tmirah Haselkorn; Weiss; Leslie C. Grammer; June H. Lee; Hubert Chen
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Ranibizumab for macular edema due to retinal vein occlusions: Implication of VEGF as a critical stimulator
Molecular Therapy, ISSN: 15250024 15250016
Peter A. Campochiaro; Gulnar Hafiz; Syed Mahmood Shah; Quan Dong Nguyen; Howard Ying; Diana V. Do; Edward Quinlan; Ingrid Zimmer-Galler; Julia A. Haller; Sharon D. Solomon; Jennifer U. Sung; Yasmin Hadi; Kashif A. Janjua; Nida Jawed; David F. Choy; Joseph R. Arron
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A key claudin extracellular loop domain is critical for epithelial barrier integrity
American Journal of Pathology, ISSN: 00029440
Mrsny; G. Thomas Brown; Kirsten Gerner-Smidt; Andre G. Buret; Jon B. Meddings; Quan; Michael Koval; Asma Nusrat
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Blockade of CD11a by efalizumab in psoriasis patients induces a unique state of T-cell hyporesponsiveness
Journal of Investigative Dermatology, ISSN: 15231747 0022202X
Emma Guttman-Yassky; Yulia Vugmeyster; Michelle A. Lowes; Francesca Chamian; Toyoko Kikuchi; Mark Kagen; Patricia Gilleaudeau; Edmund Lee; Brisdell Hunte; Howell; Wolfgang Dummer; Bodary; James G. Krueger
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Ranibizumab Combined With Verteporfin Photodynamic Therapy in Neovascular Age-related Macular Degeneration (FOCUS): Year 2 Results
American Journal of Ophthalmology, ISSN: 00029394
Andrew N. Antoszyk; Lisa Tuomi; Carol Chung; Angele Singh
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Ten-year outcomes following traumatic brain injury: A population-based cohort
Brain Injury, ISSN: 1362301X 02699052
Cameron; David M. Purdie; Kliewer; Rod J. McClure
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Prediction of the possibility of the second peak of drug plasma concentration time curve after iv bolus administration from the standpoint of the traditional multi-compartmental linear pharmacokinetics
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Leonid M. Berezhkovskiy
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Summary statement novel agents in the treatment of lung cancer: Fifth Cambridge conference assessing opportunities for combination therapy
Journal of Thoracic Oncology, ISSN: 15561380 15560864
Thomas J. Lynch; George R. Blumenschein; Jeff A. Engelman; Igor Espinoza-Delgado; Ramaswamy Govindan; Jeffrey H. Hanke; Nasser H. Hanna; John V. Heymach; Fred R. Hirsch; Pasi A. Jänne; Rogerio C. Lilenbaum; Ronald B. Natale; Gregory J. Riely; Lecia V. Sequist; Geoffrey I. Shapiro; Alice T. Shaw; Frances A. Shepherd; Mark A. Socinski; A Gregory Sorensen; Heather A. Wakelee; Aaron Weitzman
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Stopping replication, at the beginning
Nature Chemical Biology, ISSN: 15524469 15524450
Peter K Jackson
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Synthesis of a cross-bridged cyclam derivative for peptide conjugation and 64Cu radiolabeling
Bioconjugate Chemistry, ISSN: 10431802
C. Andrew Boswell; Celeste A. S. Regino; Kwamena E. Baidoo; Karen J. Wong; Ambika Bumb; Heng Xu; Diane E. Milenic; James A. Kelley; Christopher C. Lai; Martin W. Brechbiel
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Evaluation of hydrate-screening methods
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Yonc Cui; Erica Yao
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The Notch pathway in prostate development and cancer
Differentiation, ISSN: 14320436 03014681
Kevin G. Leong; Gao
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15 Capillary electrophoresis and bioanalysis
Separation Science and Technology, ISSN: 01496395
Oscar Salas-Solano; Chantal Felten
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Anti-CD22-MCC-DM1 and MC-MMAF conjugates: Impact of assay format on pharmacokinetic parameters determination
Bioconjugate Chemistry, ISSN: 10431802
Jean-Philippe Stephan; Pamela Chan; Chien C. Lee; Nelson; J. Michael Elliott; Charity Bechtel; Helga Raab; David Xie; Jon Akutagawa; Jakub Baudys; Ola M. Saad; Saileta Prabhu; Wai Lee T. Wong; Richard L. Vandlen; Fred Jacobson; Allen Ebens
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The complex inter-relationships between protein flexibility and stability
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Tim J. Kamerzell; C. Russell Middaugh
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The safety of bone allografts used in dentistry: A review
Journal of the American Dental Association, ISSN: 00028177
Dan Holtzclaw; Nicholas Toscano; Lisa Eisenlohr; Don Callan
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Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus
Nature Genetics, ISSN: 15461718 10614036
Robert R. Graham; Chris Cotsapas; Leela R. L. Davies; Rachel Hackett; Christopher J. Lessard; Joanlise M. Leon; Noel Burtt; Candace Guiducci; Melissa Parkin; Casey Gates; Robert M. Plenge; Timothy W. Behrens; Joan E. Wither; John D. Rioux; Fortin; Deborah S. Cunninghame Graham; Andrew K. Wong; Timothy J. Vyse; Mark J. Daly; David Altshuler; Kathy L. Moser; Patrick M. Gaffney
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Racial disparities in asthma-related health outcomes in severe or difficult-to-treat asthma
Annals of Allergy, Asthma and Immunology, ISSN: 15344436 10811206
Tmirah Haselkorn; June H. Lee; David R. Mink; Weiss
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Reversible self-association of a concentrated monoclonal antibody solution mediated by fab-fab interaction that impacts solution viscosity
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Sonoko Kanai; Jun Liu; Thomas W. Patapoff; Steven J. Shire
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A role of macrophage complement receptor crig in immune clearance and inflammation
Molecular Immunology, ISSN: 18729142 01615890
Jeannie Q. He; Wiesmann; Menno Van Lookeren Campagne
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Recognition of genetic factors influencing the progression of hepatitis C: Potential for personalized therapy
Molecular Diagnosis and Therapy, ISSN: 11771062
Julie R. Jonsson; David M. Purdie; Andrew D. Clouston; Elizabeth E. Powell
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