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Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 10201 - 10250 OF 15583 RESULTS

Full-length antibodies on display
Nature Biotechnology, ISSN: 10870156 15461696
Sachdev S. Sidhu
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Demographic and clinical characteristics of children and adolescents with severe or difficult-to-treat asthma
Journal of Allergy and Clinical Immunology, ISSN: 00916749
Bradley E. Chipps; Stanley J. Szefler; F. Estelle R. Simons; Tmirah Haselkorn; David R. Mink; Yamo Deniz; June H. Lee
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Selective clearance of glycoforms of a complex glycoprotein pharmaceutical caused by terminal N-acetylglucosamine is similar in humans and cynomolgus monkeys
Glycobiology, ISSN: 09596658 14602423
Andrew J.S. Jones; Damon I. Papac; Chin; Rodney Keck; Sharon A. Baughman; Yvonne S. Lin; Johannes Kneer; John E. Battersby
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Monoclonal antibody now available to prevent red blood cell breakdown.
Managed Care, ISSN: 10623388
Thomas Morrow
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Quantitative translational pharmacology for monoclonal antibody dose and dose-schedule determination
American Pharmaceutical Review, ISSN: 10998012
Nelson L'ntshotsholé Jumbe
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Targeted and untargeted CD137L fusion proteins for the immunotherapy of experimental solid tumors
Clinical Cancer Research, ISSN: 10780432
Nan Zhang; Rebecca E. Sadun; Robyn S. Arias; Meg L. Flanagan; Suzanne M. Sachsman; Yu-Chih Nien; Leslie A. Khawli; Peisheng Hu; Alan L. Epstein
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Loop anchor modification causes the population of an alternative native state in an SH3-like domain
Protein Science, ISSN: 09618368 1469896X
Jane A. Knappenberger; Juliette T.J. Lecomte
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Krüppel-like transcription factor 13 regulates T lymphocyte survival in vivo
Journal of Immunology, ISSN: 00221767
Meixia Zhou; Lisa McPherson; Dongdong Feng; An Song; Chen Dong; Shu-Chen Lye; Lu Zhou; Xiaoyan Shi; Yong-Tae Ahn; Demin Wang; Carol Clayberger; Alan M. Krensky
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Quantifying the treatment effect explained by markers in the presence of measurement error
Statistics in Medicine, ISSN: 02776715 10970258
Somnath Sarkar; Yongming Qu
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Role for Msh5 in the regulation of Ig class switch recombination
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Hideharu Sekine; Ricardo C. Ferreira; Qiang Pan-Hammarström; Robert R. Graham; Beth Ziemba; Sandra S. De Vries; Jiabin Liu; Keli Hippen; Thearith Koeuth; Ward Ortmann; Akiko Iwahori; Margaret K. Elliott; Steven Offer; Cara Skon; Likun Du; Jill Novitzke; Annette T. Lee; Nianxi Zhao; Joshua D. Tompkins; David Altshuler; Peter K. Gregersen; Charlotte Cunningham-Rundles; Reuben S. Harris; Chengtao Her; David L. Nelson; Lennart Hammarström; Gary S. Gilkeson; Timothy W. Behrens
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The BH3-Only Protein Bid Is Dispensable for DNA Damage- and Replicative Stress-Induced Apoptosis or Cell-Cycle Arrest
Cell, ISSN: 00928674
Kaufmann; Lin Tai; Paul G. Ekert; David C.S. Huang; Fiona Norris; Ralph K. Lindemann; Ricky W. Johnstone; Vishva M. Dixit; Andreas Strasser
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Spectroscopic evaluation of the stabilization of humanized monoclonal antibodies in amino acid formulations
International Journal of Pharmaceutics, ISSN: 03785173
Fei Tian; C. Russell Middaugh; Tom Offerdahl; Eric Munson; Samir Sane; J. Howard Rytting
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Netrin-1/DCC signaling in commissural axon guidance requires cell-autonomous expression of heparan sulfate
Journal of Neuroscience, ISSN: 02706474 02706474
Yoshihiro Matsumoto; Fumitoshi Irie; Masaru Inatani; Marc Tessier-Lavigne; Yu Yamaguchi
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ElaD, a deubiquitinating protease expressed by E. coli
PLoS ONE, ISSN: 19326203
André Catic; Shahram Misaghi; Gregory A. Korbel; Hidde L. Ploegh
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Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Robert R. Graham; Chieko Kyogoku; Snaevar Sigurdsson; Irina A. Vlasova; Leela R. L. Davies; Emily C. Baechler; Robert M. Plenge; Thearith Koeuth; Ward Ortmann; Geoffrey Hom; Jason W. Bauer; Clarence Gillett; Noel Burtt; Deborah S. Cunninghame Graham; Robert Onofrio; Michelle Petri; Iva Gunnarsson; Elisabet Svenungsson; Lars Rönnblom; Gunnel Nordmark; Peter K. Gregersen; Kathy L. Moser; Patrick M. Gaffney; Lindsey A. Criswell; Timothy J. Vyse; Ann-Christine Syvänen; Paul R. Bohjanen; Mark J. Daly; Timothy W. Behrens; David Altshuler
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Ala657 and conserved active site residues promote fibroblast activation protein endopeptidase activity via distinct mechanisms of transition state stabilization
Biochemistry, ISSN: 00062960
Sarah A. Meadows; Conrad Yap Edosada; Mark Mayeda; Thuy Tran; Quan; Helga Raab; Wiesmann; Beni B. Wolf
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Assays for the Release of Viral Vector Gene Therapy Products for Human Clinical Trials
Concepts in Genetic Medicine,
Flavia Borellini
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The tumour-suppressor Scribble dictates cell polarity during directed epithelial migration: Regulation of Rho GTPase recruitment to the leading edge
Oncogene, ISSN: 09509232 14765594
Dow; Kauffman; Caddy; Andrew S. Peterson; Jane; Russell; Humbert
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Plexin-B2 controls the development of cerebellar granule cells
Journal of Neuroscience, ISSN: 02706474 02706474
Roland H. Friedel; Géraldine Kerjan; Helen Rayburn; Ulrich Schüller; Constantino Sotelo; Marc Tessier-Lavigne; Alain Chedotal
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Glycosylphosphatidylinositol-Anchored High-Density Lipoprotein-Binding Protein 1 Plays a Critical Role in the Lipolytic Processing of Chylomicrons
Cell Metabolism, ISSN: 15504131
Anne P. Beigneux; Brandon S.J. Davies; Peter Gin; Michael M. Weinstein; Emily Farber; Xin Qiao; Franklin V. Peale Jr.; Bunting; Rosemary L. Walzem; Jinny S. Wong; William S. Blaner; Zhi-Ming Ding; Kristan Melford; Nuttaporn Wongsiriroj; Xiao Shu; Frederic J. De Sauvage; Robert O. Ryan; Loren G. Fong; André Bensadoun; Stephen G. Young
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Design space for biotech products
BioPharm International, ISSN: 1542166X
Anurag S. Rathore; Ron Branning; Doug Cecchini
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ASC, Ipaf and Cryopyrin/Nalp3: bona fide intracellular adapters of the caspase-1 inflammasome
Microbes and Infection, ISSN: 12864579 1769714X
Sanjeev Mariathasan
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Regulation of myeloid progenitor cell proliferation/survival by IL-31 receptor and IL-31
Experimental Hematology, ISSN: 0301472X
Hal E. Broxmeyer; Ji Li; Giao Hangoc; Scott Cooper; Wen Tao; Charlie Mantel; Barbara Graham-Evans; Nico Ghilardi; Frederic J. De Sauvage
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The 620W allele is the PTPN22 genetic variant conferring susceptibility to RA in a Dutch population
Rheumatology, ISSN: 14620324 14620332
Wesoly; Hu; Thabet; Chang; Uh; Allaart; Toes; Houwing-Duistermaat; Begovich; Tom W. J. Huizinga
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Dimethylfumarate induces immunosuppression via glutathione depletion and subsequent induction of heme oxygenase 1
Journal of Investigative Dermatology, ISSN: 0022202X 15231747
Joachim C.U. Lehmann; Joanna J. Listopad; Christine U. Rentzsch; Frederik H. Igney; Arne Von Bonin; Hartwig H. Hennekes; Khusru Asadullah; Wolf-Dietrich F. Docke
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High-throughput automated system for crystallizing membrane proteins in lipidic mesophases
IEEE Transactions on Automation Science and Engineering, ISSN: 15455955
Avinash Peddi; Lalitha Muthusubramaniam; Yuan F. Zheng; Vadim Cherezov; Yohann Misquitta; Martin Caffrey
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Basic helix-loop-helix transcription factor heterocomplex of Yas1p and Yas2p regulates cytochrome P450 expression in response to alkanes in the yeast Yarrowia lipolytica
Eukaryotic Cell, ISSN: 15359778
Setsu Endoh-Yamagami; Kiyoshi Hirakawa; Daisuke Morioka; Ryouichi Fukuda; Akinori Ohta
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Vascular targeting via caveolae
Nature Biotechnology, ISSN: 10870156 15461696
Kristy Red-Horse; Napoleone Ferrara
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Vasorelaxation induced by vascular endothelial growth factor in the human internal mammary artery and radial artery
Vascular Pharmacology, ISSN: 15371891
Wei Wei; Zhi-Wu Chen; Qin Yang; Hongkui Jin; Anthony Furnary; Xiao-Qiang Yao; Anthony P. C. Yim; Guo-Wei He
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Swapping the gene-specific and regional silencing specificities of the Hst1 and Sir2 histone deacetylases
Molecular and Cellular Biology, ISSN: 02707306
Janet Mead; Ron McCord; Laura Youngster; Mandakini Sharma; Marc R. Gartenberg; Andrew K. Vershon
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Species-dependent serum interference in a sandwich ELISA for Apo2L/TRAIL
Journal of Immunological Methods, ISSN: 00221759
Laura DeForge; Danny Shih; Derek Kennedy; Klara Totpal; Anan Chuntharapai; Bennett; Jason H. Drummond; Patricia Siguenza; Wai Lee T. Wong
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Phosphorylation of a Wiscott-Aldrich syndrome protein-associated signal complex is critical in osteoclast bone resorption
Journal of Biological Chemistry, ISSN: 00219258 1083351X
Meenakshi A. Chellaiah; Dhandapani Kuppuswamy; Larry Lasky; Stefan Linder
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Robo1 and Robo2 cooperate to control the guidance of major axonal tracts in the mammalian forebrain
Journal of Neuroscience, ISSN: 02706474 02706474
Guillermina López-Bendito; Nuria Flames; Le Ma; Coralie Fouquet; Thomas Di Meglio; Alain Chedotal; Marc Tessier-Lavigne; Oscar Marín
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Utilizing the activation mechanism of serine proteases to engineer hepatocyte growth factor into a Met antagonist
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Daniel Kirchhofer; Michael T. Lipari; Santell; Karen L Billeci; Henry R. Maun; Wendy N. Sandoval; Paul Moran; John B.B. Ridgway; Eigenbrot; Lazarus
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Substrate tolerance of module 6 of the epothilone synthetase
Biochemistry, ISSN: 00062960
Martha Lovato Tse; R. Edward Watts; Chaitan Khosla
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IL-31-IL-31R interactions negatively regulate type 2 inflammation in the lung
Journal of Experimental Medicine, ISSN: 00221007 00221007
Jacqueline G. Perrigoue; Ji Li; Colby Zaph; Michael Goldschmidt; Phillip Scott; Frederic J. De Sauvage; Edward J. Pearce; Nico Ghilardi; David Artis
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Future of antibody purification
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, ISSN: 15700232
Duncan Low; O'Leary; Narahari Pujar
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Translational unmasking of Emi2 directs cytostatic factor arrest in meiosis II
Cell Cycle, ISSN: 15514005 15384101
Jeffrey J. Tung; Kiran Padmanabhan; David V. Hansen; Joel D. Richter; Peter K Jackson
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Emi2 at the crossroads: Where CSF meets MPF
Cell Cycle, ISSN: 15514005 15384101
David V. Hansen; Joseph R. Pomerening; Matthew K. Summers; Julie J. Miller; James E. Ferrell Jr.; Peter K Jackson
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Robustness of a multivariate normal approximation for imputation of incomplete binary data
Statistics in Medicine, ISSN: 02776715 10970258
Coen A. Bernaards; Thomas R. Belin; Joseph L. Schafer
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Facilitating matched pairing and expression of TCR chains introduced into human T cells
Blood, ISSN: 00064971 00064971
Jürgen Kuball; Michelle L. Dossett; Matthias Wolfl; William Y. Ho; Ralf-Holger Voss; Carla Fowler; Philip D. Greenberg
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Robo1 and Robo2 control the development of the lateral olfactory tract
Journal of Neuroscience, ISSN: 02706474 02706474
Coralie Fouquet; Thomas Di Meglio; Le Ma; Takahiko Kawasaki; Hua Long; Tatsumi Hirata; Marc Tessier-Lavigne; Alain Chedotal; Kim T. Nguyen-Ba-Charvet
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Expression of protein elongation factor eEF1A2 predicts favorable outcome in breast cancer
Breast Cancer Research and Treatment, ISSN: 01676806
Geeta Kulkarni; Dmitry A. Turbin; Anahita Amiri; Sujeeve Jeganathan; Miguel A. Andrade-Navarro; Thomas D Wu; David G. Huntsman; Jonathan M. Lee
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Cardiotrophin-1 is an essential factor in the natural defense of the liver against apoptosis
Hepatology, ISSN: 02709139
Juan M. Marquès; Idoia Belza; Bettina Holtmann; Diane Pennica; Jesús Prieto; Matilde Bustos
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Current development of clinical inhibitors of poly(ADP-ribose) polymerase in oncology
Clinical Cancer Research, ISSN: 10780432
Kapila Ratnam; Low
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Hepatocyte growth factor activator inhibitor-1 (HAI-1) is essential for the integrity of basement membranes in the developing placental labyrinth
Developmental Biology, ISSN: 00121606
Bin Fan; Jane Brennan; Deanna Grant; Franklin V. Peale Jr.; Linda Rangell; Daniel Kirchhofer
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Unified Manufacturing Control System (MCS) architecture for pharmaceutical and biotech manufacturing
Pharmaceutical Engineering, ISSN: 02738139
Ronald E. Menéndez; Darrell Tanner
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Loss of the BH3-only protein Bid does not rescue RelA-deficient embryos from TNF-R1-mediated fatal hepatocyte destruction [2]
Cell Death and Differentiation, ISSN: 13509047 14765403
Kaufmann; Gugasyan; Gerondakis; Vishva M. Dixit; Andreas Strasser
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Infant care patterns at epidemiologic study of cystic fibrosis sites that achieve superior childhood lung function
Pediatrics, ISSN: 00314005 02105721
Raj Padman; Susanna A. McColley; Dave P. Miller; Michael W. Konstan; Morgan; Michael S. Schechter; Clement L. Ren; Wagener
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A Role for Nogo Receptor in Macrophage Clearance from Injured Peripheral Nerve
Neuron, ISSN: 08966273
Elizabeth J. Fry; Carole Ho; Samuel David
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