Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 10301 - 10350 OF 15632 RESULTS

Hepatocyte growth factor activator inhibitor-1 (HAI-1) is essential for the integrity of basement membranes in the developing placental labyrinth
Developmental Biology, ISSN: 00121606
Bin Fan; Jane Brennan; Deanna Grant; Franklin V. Peale Jr.; Linda Rangell; Daniel Kirchhofer
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Current development of clinical inhibitors of poly(ADP-ribose) polymerase in oncology
Clinical Cancer Research, ISSN: 10780432
Kapila Ratnam; Low
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Cardiotrophin-1 is an essential factor in the natural defense of the liver against apoptosis
Hepatology, ISSN: 02709139
Juan M. Marquès; Idoia Belza; Bettina Holtmann; Diane Pennica; Jesús Prieto; Matilde Bustos
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Expression of protein elongation factor eEF1A2 predicts favorable outcome in breast cancer
Breast Cancer Research and Treatment, ISSN: 01676806
Geeta Kulkarni; Dmitry A. Turbin; Anahita Amiri; Sujeeve Jeganathan; Miguel A. Andrade-Navarro; Thomas D Wu; David G. Huntsman; Jonathan M. Lee
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Mice expressing a humanized form of VEGF-A may provide insights into the safety and efficacy of anti-VEGF antibodies
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Hans-Peter Gerber; Xiumin Wu; Lanlan Yu; Wiesmann; Xiao Huan Liang; Chingwei V. Lee; Fuh; Christine Olsson; Lisa A. Damico; David Xie; Meng; Johnny Gutierrez; Corpuz; Bing Li; Linda Hall; Linda Rangell; Ron Ferrando; Henry B. Lowman; Franklin V. Peale Jr.; Napoleone Ferrara
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Identification of IGF2 signaling through phosphoinositide-3-kinase regulatory subunit 3 as a growth-promoting axis in glioblastoma
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Liliana Soroceanu; Samir Kharbanda; Ruihuan Chen; Robert Soriano; Kenneth D. Aldape; Anjan Misra; Jiping Zha; William F. Forrest; Janice M. Nigro; Zora Modrusan; Burt G. Feuerstein; Phillips
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Eruptive papules during efalizumab (anti-CD11a) therapy of psoriasis vulgaris: A case series
BMC Dermatology, ISSN: 14715945
Michelle A. Lowes; Francesca Chamian; Maria V. Abello; Craig Leonardi; Wolfgang Dummer; Kim Papp; James G. Krueger
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Function Blocking Antibodies to Neuropilin-1 Generated from a Designed Human Synthetic Antibody Phage Library
Journal of Molecular Biology, ISSN: 00222836
Wei-Ching Liang; Dennis; Scott Stawicki; Yvan Chanthery; Qi Pan; Yongmei Chen; Eigenbrot; Jianping Yin; Alexander W. Koch; Xiumin Wu; Napoleone Ferrara; Anil Bagri; Marc Tessier-Lavigne; Ryan J. Watts; Yan Wu
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Efficacy and safety of single-agent pertuzumab (rhuMAb 2C4), a human epidermal growth factor receptor dimerization inhibitor, in castration-resistant prostate cancer after progression from taxane-based therapy
Journal of Clinical Oncology, ISSN: 0732183X
David B. Agus; Christopher J. Sweeney; Michael J. Morris; David Mendelson; Douglas G. McNeel; Frederick R. Ahmann; Jin Wang; Mika K. Derynck; Kimmie Ng; Benjamin Lyons; David E. Allison; Michael W. Kattan; Scher
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Efficacy and safety of single-agent pertuzumab (rhuMAb 2C4), a human epidermal growth factor receptor dimerization inhibitor, in castration-resistant prostate cancer after progression from taxane-based therapy
Journal of Clinical Oncology, ISSN: 0732183X
Agus; Christopher J. Sweeney; Michael J. Morris; David Mendelson; Douglas G. McNeel; Frederick R. Ahmann; Jin Wang; Mika K. Derynck; Kimmie Ng; Benjamin Lyons; David E. Allison; Michael W. Kattan; Scher
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The effects of IL-20 subfamily cytokines on reconstituted human epidermis suggest potential roles in cutaneous innate defense and pathogenic adaptive immunity in psoriasis
Journal of Immunology, ISSN: 00221767
Susan Sa; Patricia A. Valdez; Jianfeng Wu; Kenneth Jung; Fiona Zhong; Linda Hall; Ian Kasman; Jane Winer; Zora Modrusan; Dimitry Danilenko; Wenjun Ouyang
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Ion exchange chromatography of antibody fragments
Biotechnology and Bioengineering, ISSN: 00063592 10970290
Anders Ljunglöf; Karol M. Lacki; Jay Mueller; Chithkala Harinarayan; Robert Van Reis; Fahrner; James M. Van Alstine
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Dr. Rosenfeld and colleagues reply [13]
New England Journal of Medicine, ISSN: 00284793 15334406
Philip J. Rosenfeld; David M. Brown; Susan Schneider
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Aspartate isomerization in the complementarity-determining regions of two closely related monoclonal antibodies
Biochemistry, ISSN: 00062960
Aditya A. Wakankar; Ronald T. Borchardt; Eigenbrot; Steven Shia; Y. John Wang; Steven J. Shire; Jun Liu
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Novel genomic effects of glucocorticoids in epidermal keratinocytes: Inhibition of apoptosis, interferon-γ pathway, and wound healing along with promotion of terminal differentiation
Journal of Biological Chemistry, ISSN: 1083351X 00219258
Olivera Stojadinovic; Brian Lee; Constantinos Vouthounis; Sasa Vukelic; Irena Pastar; Miroslav Blumenberg; Harold Brem; Marjana Tomic-Canic
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Interleukin-22, a TH17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis
Nature, ISSN: 14764687 00280836
Yan Zheng; Dimitry Danilenko; Patricia A. Valdez; Ian Kasman; Jeffrey Eastham-Anderson; Jianfeng Wu; Wenjun Ouyang
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A Role for Cdc2- and PP2A-Mediated Regulation of Emi2 in the Maintenance of CSF Arrest
Current Biology, ISSN: 09609822
Judy Qiju Wu; Yanxiang Guo; Ayumi Yamada; Jennifer A. Perry; Michael Zhuo Wang; Marito Araki; Christopher D. Freel; Jeffrey J. Tung; Wanli Tang; Seth S. Margolis; Peter K Jackson; Hiroyuki Yamano; Maki Asano; Sally Kornbluth
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Subgroup Analysis of the MARINA Study of Ranibizumab in Neovascular Age-Related Macular Degeneration
Ophthalmology, ISSN: 01616420
David S. Boyer; Andrew N. Antoszyk; Carl C. Awh; Robert B. Bhisitkul; Howard Shapiro; Nisha R. Acharya
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Pattern recognition of sleep in rodents using piezoelectric signals generated by gross body movements
IEEE Transactions on Biomedical Engineering, ISSN: 00189294
Aaron E. Flores; Judith E. Flores; Hrishikesh Deshpande; Jorge A. Picazo; Xinmin Xie; Paul Franken; H. Craig Heller; Dennis A. Grahn; Bruce F. O'Hara
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Erlotinib directly inhibits HER2 kinase activation and downstream signaling events in intact cells lacking epidermal growth factor receptor expression
Cancer Research, ISSN: 00085472
Gabriele Schaefer; Lily Shao; Klara Totpal; Robert W. Akita
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The many ways of Wnt in cancer
Current Opinion in Genetics and Development, ISSN: 0959437X
Paul G. Polakis
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Endothelium-Microenvironment Interactions in the Developing Embryo and in the Adult
Developmental Cell, ISSN: 15345807
Kristy Red-Horse; Yongping Crawford; Farbod Shojaei; Napoleone Ferrara
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pH transients during salt removal in isoelectric trapping separations: A curse revisited
Electrophoresis, ISSN: 01730835 15222683
Evan Shave; Gyula Vigh
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Putting Transcription Repression and Protein Destruction in pRb's Pocket
Developmental Cell, ISSN: 15345807
Emmy W. Verschuren; Peter K Jackson
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A promising theory stumbles in clinical trials.
Managed Care, ISSN: 10623388
Thomas Morrow
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Combination of abundant protein depletion and Multi-Lectin Affinity Chromatography (M-LAC) for plasma protein biomarker discovery
Journal of Proteome Research, ISSN: 15353893
Tatiana Plavina; Eric Wakshull; William S. Hancock; Marina Hincapie
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Extent, patterns, and burden of uncontrolled disease in severe or difficult-to-treat asthma
Allergy: European Journal of Allergy and Clinical Immunology, ISSN: 01054538 13989995
Sean D. Sullivan; Lawrence Rasouliyan; Russo; Tripthi V. Kamath; Bradley E. Chipps
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Identification of Rab11 as a small GTPase binding protein for the Evi5 oncogene
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Christopher J. Westlake; Jagath R. Junutula; Glenn C. Simon; Manohar Pilli; Rytis Prekeris; Richard H. Scheller; Peter K Jackson; Adam G. Eldridge
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IL-25 regulates Th17 function in autoimmune inflammation
Journal of Experimental Medicine, ISSN: 00221007 00221007
Melanie A. Kleinschek; Alexander M. Owyang; Barbara Joyce-Shaikh; Claire L. Langrish; Yi Chen; Daniel M. Gorman; Wendy M. Blumenschein; Terrill McClanahan; Frank Brombacher; Stephen D. Hurst; Robert A. Kastelein; Daniel J. Cua
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FBXO11 promotes the neddylation of p53 and inhibits its transcriptional activity
Journal of Biological Chemistry, ISSN: 00219258 1083351X
Wassim M. Abida; Anatoly Nikolaev; Wenhui Zhao; Wenzhu Zhang; Wei Gu
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Distinguishing cancer-associated missense mutations from common polymorphisms
Cancer Research, ISSN: 00085472
Joshua S. Kaminker; Yan Zhang; Allison Waugh; Matthias Peter; Brock A. Peters; Dragan Sebisanovic; Stinson; William F. Forrest; J.Fernando Bazan; Somasekar Seshagiri; Zemin Zhang
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The Hh signaling pathway in cancer.
Bulletin et mémoires de l'Académie royale de médecine de Belgique, ISSN: 03778231
Frederic J. De Sauvage
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Ranibizumab for Predominantly Classic Neovascular Age-related Macular Degeneration: Subgroup Analysis of First-year ANCHOR Results
American Journal of Ophthalmology, ISSN: 00029394
Peter K. Kaiser; David M. Brown; Kang Zhang; Henry L. Hudson; Frank G. Holz; Howard Shapiro; Susan Schneider; Nisha R. Acharya
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Human-derived clotting agent avoids immunogenicity
Managed Care, ISSN: 10623388
Thomas Morrow
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On the determination of the time delay in reaching the steady state drug concentration in the organ compared to plasma
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Leonid M. Berezhkovskiy
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Risk factors associated with persistent airflow limitation in severe or difficult-to-treat asthma: Insights from the TENOR study
Chest, ISSN: 00123692
June H. Lee; Tmirah Haselkorn; Larry Borish; Lawrence Rasouliyan; Bradley E. Chipps; Sally E. Wenzel
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Should clinical complications affect USDA pain categories? C is correct.
Lab Animal, ISSN: 00937355
Gail T. Colbern; Lisa Heath
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Cryoablation for atrial flutter requires no anesthesia
Managed Care, ISSN: 10623388
Thomas Morrow
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A self-developed prechemotherapy education checklist.
Clinical journal of oncology nursing, ISSN: 10921095
Peggy S Mueller; Catherine A Glennon
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A naturally occurring truncated β3 integrin in tumor cells: Native anti-integrin involved in tumor cell motility
Cancer Biology and Therapy, ISSN: 15558576 15384047
Rongxian Jin; Mohit Trikha; Yinlong Cai; David Grignon; Kenneth V. Honn
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Angiographic and Optical Coherence Tomographic Results of the MARINA Study of Ranibizumab in Neovascular Age-Related Macular Degeneration
Ophthalmology, ISSN: 01616420
Peter K. Kaiser; Barbara A. Blodi; Howard Shapiro; Nisha R. Acharya
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Gene expression microarray improves prediction of breast cancer outcomes
Managed Care, ISSN: 10623388
Thomas Morrow
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Risk Factors For Rate of Decline in Forced Expiratory Volume in One Second in Children and Adolescents with Cystic Fibrosis
Journal of Pediatrics, ISSN: 00223476
Michael W. Konstan; Morgan; Butler; David J. Pasta; Marcia L. Craib; Stefanie J. Silva; Dennis C. Stokes; Mary Ellen Wohl; Wagener; Warren E. Regelmann; Charles A. Johnson
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Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion
Nature Cell Biology, ISSN: 14657392
Katarina Wolf; Yi I. Wu; Yueying Liu; Jörg Geiger; Eric Tam; Christopher Overall; M. Sharon Stack; Peter Friedl
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The effect of cosolutes on the isomerization of aspartic acid residues and conformational stability in a monoclonal antibody
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Aditya A. Wakankar; Jun Liu; David Vandervelde; Y. John Wang; Steven J. Shire; Ronald T. Borchardt
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Implications of pharmacogenomics in the current and future treatment of asthma
Journal of Managed Care Pharmacy, ISSN: 10834087
Thomas Morrow
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Lack of augmentation of tumor spectrum or severity in dual heterozygous Men1 and Rb1 knockout mice
Oncogene, ISSN: 14765594 09509232
Loffler; Biondi; Gartside; Serewko-Auret; Duncan; Tonks; Mould; Waring; Muller; Kay; Hayward
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Progressive Fibrosis in Nonalcoholic Steatohepatitis: Association With Altered Regeneration and a Ductular Reaction
Gastroenterology, ISSN: 00165085
Michelle M. Richardson; Julie R. Jonsson; Elizabeth E. Powell; Elizabeth M. Brunt; Brent A. Neuschwander-Tetri; Prithi S. Bhathal; John B. Dixon; Martin D. Weltman; Herbert Tilg; Alexander R. Moschen; David M. Purdie; Anthony J. Demetris; Andrew D. Clouston
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Cox regression methods for two-stage randomization designs
Biometrics, ISSN: 15410420 0006341X
Yuliya Lokhnygina; Jeffrey D. Helterbrand
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Fluid support worsens outcome and negates the benefit of protective antigen-directed monoclonal antibody in a lethal toxin-infused rat Bacillus anthracis shock model
Critical Care Medicine, ISSN: 00903493
Kevin Sherer; Yan Li; Xizhong Cui; Xuemei Li; Mani Subramanian; Mike Laird; Mahtab Moayeri; Stephen H. Leppla; Yvonne Fitz; Junwu Su; Peter Q. Eichacker
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