Scientists / Publications

Publications

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DISPLAYING 10351 - 10400 OF 15583 RESULTS

Enhanced half-life of genetically engineered human IgG1 antibodies in a humanized FcRn mouse model: Potential application in humorally mediated autoimmune disease
International Immunology, ISSN: 09538178 14602377
Stefka B. Petkova; Shreeram Akilesh; Thomas J. Sproule; Gregory J. Christianson; Hana Al Khabbaz; Aaron C. Brown; Presta; Meng; Derry C. Roopenian
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Glucuronidation in the chimpanzee (Pan troglodytes): Studies with acetaminophen, oestradiol and morphine
Xenobiotica, ISSN: 00498254 13665928
Harvey Wong; James E. Grace Jr.; Matthew Wright; Browning; Grossman; Bai; David D. Christ
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Genetics of autoimmune diseases - Disorders of immune homeostasis
Nature Reviews Genetics, ISSN: 14710056 14710064
Peter K. Gregersen; Timothy W. Behrens
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Transgenic mouse proteomics identifies new 14-3-3-associated proteins involved in cytoskeletal rearrangements and cell signaling
Molecular and Cellular Proteomics, ISSN: 15359476
Pierre-Olivier Angrand; Inmaculada Segura; Pamela Völkel; Sonja Ghidelli; Rebecca Terry; Miro Brajenovic; Kristina Vintersten; Rüdiger Klein; Giulio Superti-Furga; Gerard Drewes; Bernhard Kuster; Tewis Bouwmeester; Amparo Acker-Palmer
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Sustained benefit in rheumatoid arthritis following one course of rituximab: Improvements in physical function over 2 years
Rheumatology, ISSN: 14620324 14620332
Vibeke Strand; Balbir-Gurman; Karel Pavelka; Paul Emery; Nicole F. Li; Ming Yin; Lehane; Sunil Agarwal
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Concluding summary: Proceedings of the AAPS Biotec Open Forum on "Aggregation of Protein Therapeutics"
AAPS Journal, ISSN: 15507416
Steven J. Shire; Cromwell; Jun Liu
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Protein NMR Spectroscopy: Principles and Practice
Protein NMR Spectroscopy: Principles and Practice,
John Cavanagh; Wayne J. Fairbrother; Arthur G. Palmer III; Mark Rance; Nicholas J. Skelton
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Selectivity improvements in highly charged UF membranes
Desalination, ISSN: 00119164
Alex Xenopoulos; Charkoudian; Robert Van Reis
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Boc is a receptor for sonic hedgehog in the guidance of commissural axons
Nature, ISSN: 14764687 00280836
Ami Okada; Frédéric Charron; Steves Morin; David S. Shin; Karen G. Wong; Pierre J. Fabre; Marc Tessier-Lavigne; Susan K. McConnell
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Rab14 is critical for maintenance of Mycobacterium tuberculosis phagosome maturation arrest
EMBO Journal, ISSN: 02614189 14602075
George B. Kyei; Isabelle Vergne; Jennifer Chua; Esteban Roberts; James Harris; Jagath R. Junutula; Vojo Deretic
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Structure of C3b in complex with CRIg gives insights into regulation of complement activation
Nature, ISSN: 14764687 00280836
Wiesmann; Kenneth J. Katschke Jr.; Jianping Yin; Karim Y. Helmy; Micah Steffek; Wayne J. Fairbrother; Scott A. McCallum; Lizette Sturgeon; Laura DeForge; Hass; Menno Van Lookeren Campagne
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Reply to Challenges to the report of Nogo antibody effects in primates [4]
Nature Medicine, ISSN: 10788956 1546170X
Carole Ho; Marc Tessier-Lavigne
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Technical considerations in the development of prefilled syringes for protein products
American Pharmaceutical Review, ISSN: 10998012
David E. Overcashier; Edwin K. Chan; Chung C. Hsu
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Alteplase for the treatment of central venous catheter occlusion in children: Results of a prospective, open-label, single-arm study (The Cathflo Activase Pediatric Study)
Journal of Vascular and Interventional Radiology, ISSN: 10510443
Martha Blaney; Violet Shen; John A. Kerner; Brian R. Jacobs; Sarah Gray; Jennifer Armfield; Charles P. Semba
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Quality by design, validation, and PAT: Operational, statistical, and engineering perspectives
Pharmaceutical Engineering, ISSN: 02738139
Ron Branning; Lynn Torbeck; Cliff Campbell
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Ranibizumab combined with verteporfin photodynamic therapy in neovascular age-related macular degeneration: Year 1 results of the FOCUS study
Archives of Ophthalmology, ISSN: 00039950 00039950
Jeffrey S. Heier; David S. Boyer; Thomas A. Ciulla; Philip J. Ferrone; J. Michael Jumper; Ronald C. Gentile; Debbie Kotlovker; Carol Chung; Robert Kim
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The process engineer's role in technology transfers to CMOs
American Pharmaceutical Outsourcing, ISSN: 15296318
Bender
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Loss of T-cell protein tyrosine phosphatase induces recycling of the platelet-derived growth factor (PDGF) β-receptor but not the PDGF α-receptor
Molecular Biology of the Cell, ISSN: 10591524
Susann Karlsson; Katarzyna Kowanetz; Åsa Sandin; Camilla Persson; Arne Östman; Carl-Henrik Heldin; Carina Hellberg
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Synthetic anti-BR3 antibodies that mimic BAFF binding and target both human and murine B cells
Blood, ISSN: 00064971 00064971
Chingwei V. Lee; Sarah G. Hymowitz; Heidi J. A. Wallweber; Nathaniel C. Gordon; Karen L Billeci; Siao Ping Tsai; Deanne M. Compaan; Jianping Yin; Qian Gong; Robert F. Kelley; Laura DeForge; Flavius Martin; Melissa A. Starovasnik; Fuh
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Reply to Challenges to the report of Nogo antibody effects in primates [4]
Nature Medicine, ISSN: 10788956 1546170X
Carole Ho; Marc Tessier-Lavigne
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CXCL12 and C5a trigger cell migration via a PAK1/2-p38α MAPK-MAPKAP-K2-HSP27 pathway
Cellular Signalling, ISSN: 08986568
Simon Rousseau; Ignacio Dolado; Victoria Beardmore; Natalia Shpiro; Rodolfo Marquez; Angel R. Nebreda; J. Simon C. Arthur; Lauren C Case; Marc Tessier-Lavigne; Matthias Gaestel; Ana Cuenda; Philip Cohen
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Preclinical pharmacokinetics and metabolism of 6-(4- (2,5-Difluorophenyl)oxazol-5-yk)-3-isopropyl-[1,2,4]-triazolo[4,3- a]pyridine, a novel and selective p38α inhibitor: Identification of an active metaboline in preclinical species and human liver microsomes
Biopharmaceutics and Drug Disposition, ISSN: 01422782 1099081X
Amit S. Kalgutkar; Heather L. Hatch; Frederick Kosea; Hang T. Nguyen; Edna F. Choo; Kim F. McClure; Timothy J. Taylor; Kirk R. Henne; Alexander V. Kuperman; Mark A. Dombroski; Michael A. Letavic
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Magnetic resonance angiography reveals therapeutic enlargement of collateral vessels induced by VEGF in a murine model of peripheral arterial disease
Journal of Magnetic Resonance Imaging, ISSN: 10531807 15222586
Joan M. Greve; Chico; Hope Goldman; Bunting; Franklin V. Peale Jr.; Daugherty; Nicholas Van Bruggen; Simon P. Williams
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Distinct signaling pathways in TRAIL- versus tumor necrosis factor-induced apoptosis
Molecular and Cellular Biology, ISSN: 02707306
Zhaoyu Jin; Wafik S. El-Deiry
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Rapid redistribution of synaptic PSD-95 in the neocortex in vivo
PLoS Biology, ISSN: 15457885 15457885
Noah W. Gray; Robby M. Weimer; Ingrid Bureau; Karel Svoboda
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Human immunodeficiency virus persistence and production in T-cell development
Clinical and Vaccine Immunology, ISSN: 15566811
Kevin B. Gurney; Christel H. Uittenbogaart
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Inhibitory effect of carboxylic acid group on hERG binding
Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X
Bing-Yan Zhu; Zhaozhong J. Jia; Penglie Zhang; Ting Su; Wenrong Huang; Erick Goldman; Daniel B. Tumas; Vic Kadambi; Priya Eddy; Uma Sinha; Robert M. Scarborough; Yonghong Song
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Allowing for missing data at highly polymorphic genes when testing for maternal, offspring and maternal-fetal genotype incompatibility effects
Human Heredity, ISSN: 00015652
Hsin-Ju Hsieh; Christina G.S. Palmer; Janet S. Sinsheimer
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Ranibizumab combined with verteporfin photodynamic therapy in neovascular age-related macular degeneration: Year 1 results of the FOCUS study
Archives of Ophthalmology, ISSN: 00039950 00039950
Jeffrey S. Heier; David S. Boyer; Thomas A. Ciulla; Philip J. Ferrone; J. Michael Jumper; Ronald C. Gentile; Debbie Kotlovker; Carol Y. Chung; Robert Kim
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Corneal avascularity is due to soluble VEGF receptor-1
Nature, ISSN: 14764687 00280836
Balamurali K. Ambati; Miho Nozaki; Nirbhai Singh; Atsunobu Takeda; Pooja D. Jani; Tushar Suthar; Romulo J. C. Albuquerque; Elizabeth Richter; Eiji Sakurai; Michael T. Newcomb; Mark E. Kleinman; Ruth Caldwell; Qing Lin; Yuichiro Ogura; Angela Orecchia; Don A. Samuelson; Dalen W. Agnew; Judy St. Leger; W. Richard Green; Parameshwar J. Mahasreshti; David T. Curiel; Donna Kwan; Helene Marsh; Sakae Ikeda; Lucy J. Leiper; J. Martin Collinson; Sasha Bogdanovich; Tejvir S. Khurana; Masabumi Shibuya; Megan E. Baldwin; Napoleone Ferrara; Hans-Peter Gerber; Sandro De Falco; Jassir Witta; Judit Z. Baffi; Brian J. Raisler; Jayakrishna Ambati
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A novel one-armed anti-c-Met antibody inhibits glioblastoma growth in vivo
Clinical Cancer Research, ISSN: 10780432
Tobias Martens; Nils-Ole Schmidt; Carmen Eckerich; Regina Filibrandt; Mark Merchant; Ralph H. Schwall; Manfred Westphal; Katrin Lamszus
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The Hedgehog signaling pathway in cancer
Clinical Cancer Research, ISSN: 10780432
Marie Evangelista; Hua Tian; Frederic J. De Sauvage
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Polyclonal resistance in gastrointestinal stromal tumor treated with sequential kinase inhibitors [3]
Clinical Cancer Research, ISSN: 10780432
Loughrey; Waring; Dobrovic; George Demetri; Kovalenko; McArthur
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2005 AAPS Biotechnology Conference Open Forum on Aggregation of Protein Therapeutics - Panel discussion June 5-8, 2005 San Francisco, CA
AAPS Journal, ISSN: 15507416
Steven J. Shire
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Pro-urokinase-type plasminogen activator is a substrate for hepsin
Journal of Biological Chemistry, ISSN: 00219258 1083351X
Paul Moran; Wei Li; Bin Fan; Rajesh Vij; Eigenbrot; Daniel Kirchhofer
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Ranibizumab for neovascular age-related macular degeneration
New England Journal of Medicine, ISSN: 00284793 15334406
Philip J. Rosenfeld; David M. Brown; Jeffrey S. Heier; David S. Boyer; Peter K. Kaiser; Carol Chung; Robert Kim
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Ranibizumab versus verteporfin for neovascular age-related macular degeneration
New England Journal of Medicine, ISSN: 00284793 15334406
David M. Brown; Peter K. Kaiser; Mark Michels; Gisele Soubrane; Jeffrey S. Heier; Robert Kim; Judy P. Sy; Susan Schneider
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Ranibizumab versus Verteporfin Photodynamic Therapy for Neovascular Age-Related Macular Degeneration: Two-Year Results of the ANCHOR Study
Ophthalmology, ISSN: 01616420
David M. Brown; Mark Michels; Peter K. Kaiser; Jeffrey S. Heier; Judy P. Sy; Tsontcho Ianchulev
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Ranibizumab for neovascular age-related macular degeneration
New England Journal of Medicine, ISSN: 00284793 15334406
Philip J. Rosenfeld; David M. Brown; Jeffrey S. Heier; David S. Boyer; Peter K. Kaiser; Carol Y. Chung; Robert Kim
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Structure of SAP18: A ubiquitin fold in histone deacetylase complex assembly
Biochemistry, ISSN: 00062960
Scott A. McCallum; J.Fernando Bazan; Mark Merchant; Jianping Yin; Borlan Pan; Frederic J. De Sauvage; Wayne J. Fairbrother
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Imaging tumor angiogenesis
Journal of Clinical Investigation, ISSN: 00219738 15588238
Kristy Red-Horse; Napoleone Ferrara
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A review of malignancies observed during efalizumab (Raptiva®) clinical trials for plaque psoriasis
Dermatology, ISSN: 10188665
Craig Leonardi; Darryl P. Toth; Jennifer C. Cather; Richard G. B. Langley; Winifred Werther; Peter Compton; Paul Kwon; Graham Wetherill; Francois Curtin; Alan Menter
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The lack of cardiotrophin-1 alters expression of interleukin-6 and leukemia inhibitory factor mRNA but does not impair cardiac injury response
Cytokine, ISSN: 10434666
Kurt Gritman; Donna M. Van Winkle; Christina U. Lorentz; Diane Pennica; Beth A. Habecker
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Ophthalmological and otological problems in Turner syndrome
International Congress Series, ISSN: 05315131
Saenger; Nussbaum; Barbara M. Lippe
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Development of ranibizumab, an anti-vascular endothelial growth factor antigen binding fragment, as therapy for neovascular age-related macular degeneration
Retina, ISSN: 0275004X
Napoleone Ferrara; Lisa A. Damico; Naveed Shams; Henry B. Lowman; Robert Kim
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Early coronary revascularization diminishes the risk of ischemic stroke with acute myocardial infarction
Stroke, ISSN: 00392499
Eric Van De Graaff; Monisha Dutta; Pranab Das; Eric A. Shry; Paul D. Frederick; Martha Blaney; David J. Pasta; Steven R. Steinhubl
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The inhibitor of apoptosis protein fusion c-IAP2·MALT1 stimulates NF-κB activation independently of TRAF1 and TRAF2
Journal of Biological Chemistry, ISSN: 00219258 1083351X
Eugene Varfolomeev; Sarah M. Wayson; Vishva M. Dixit; Wayne J. Fairbrother; Domagoj Vucic
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A critical review of analytical ultracentrifugation and field flow fractionation methods for measuring protein aggregation
AAPS Journal, ISSN: 15507416
Jun Liu; Andya; Steven J. Shire
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Monopolar Attachment of Sister Kinetochores at Meiosis I Requires Casein Kinase 1
Cell, ISSN: 00928674
Mark Petronczki; Joao Matos; Saori Mori; Juraj Gregan; Aliona Bogdanova; Martin Schwickart; Karl Mechtler; Katsuhiko Shirahige; Wolfgang Zachariae; Kim Nasmyth
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SNAREs - Engines for membrane fusion
Nature Reviews Molecular Cell Biology, ISSN: 14710072 14710080
Reinhard Jahn; Richard H. Scheller
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