Genentech: Publications

April 1, 2004

HER2-Targeted Therapy Reduces Incidence and Progression of Midlife Mammary Tumors in Female Murine Mammary Tumor Virus huHER2-Transgenic Mice

Clinical Cancer Research, ISSN: 10780432

David Finkle; Zhi Ricky Quan; Vida Asghari; Jessica Kloss; Nazli Ghaboosi; Elaine Mai; Wai Lee T. Wong; Hollingshead; Ralph H. Schwall; Koeppen; Sharon Erickson

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April 1, 2004

Trastuzumab in combination with cisplatin and gemcitabine in patients with Her2-overexpressing, untreated, advanced non-small cell lung cancer: Report of a phase II trial and findings regarding optimal identification of patients with Her2-overexpressing disease

Lung Cancer, ISSN: 01695002

Ralph G. Zinner; Bonnie S. Glisson; Frank V. Fossella; Katherine M.W. Pisters; Merril S. Kies; Pamela M. Lee; Erminia Massarelli; Bradley Sabloff; Herbert A. Fritsche Jr.; Jae Y. Ro; Nelson G. Ordonez; Hai T. Tran; Ying Yang; Terry L. Smith; Robert Mass; Roy S. Herbst

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March 30, 2004

Rescue of NGF-deficient mice I: Transgenic expression of NGF in skin rescues mice lacking endogenous NGF

Molecular Brain Research, ISSN: 0169328X

Susan M.W. Harrison; Davis; Merry Nishimura; Albers; Marc E. Jones; Phillips

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March 29, 2004

Localization of the AP-3 adaptor complex defines a novel endosomal exit site for lysosomal membrane proteins

Journal of Cell Biology, ISSN: 00219525

Andrew A. Peden; Viola Oorschot; Boris A. Hesser; Cary D. Austin; Richard H. Scheller; Judith Klumperman

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March 12, 2004

The Crystal Structure of Placental Growth Factor in Complex with Domain 2 of Vascular Endothelial Growth Factor Receptor-1

Journal of Biological Chemistry, ISSN: 00219258

Hans W. Christinger; Fuh; De Vos; Wiesmann

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March 12, 2004

Expansion of Protein Interaction Maps by Phage Peptide Display Using MDM2 as a Prototypical Conformationally Flexible Target Protein

Journal of Molecular Biology, ISSN: 00222836

Lindsay Burch; Harumi Shimizu; Amanda Smith; Cam Patterson; Ted R. Hupp

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March 5, 2004

Albumin Stimulates the Accumulation of Extracellular Matrix in Renal Tubular Epithelial Cells

American Journal of Nephrology, ISSN: 02508095

Jean-Philippe Stephan; Mao; Ellen H. Filvaroff; Liping Cai; Ralph Rabkin; Pan

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March 5, 2004

High-Level Accumulation of a Recombinant Antibody Fragment in the Periplasm of Escherichia coli Requires a Triple-Mutant (degP prc spr) Host Strain

Biotechnology and Bioengineering, ISSN: 00063592

Christina Y. Chen; Snedecor; Julie C. Nishihara; John C. Joly; Nancy McFarland; Dana C. Andersen; John E. Battersby; Kathleen M. Champion

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March 4, 2004

EG-VEGF and Bv8: A novel family of tissue-restricted angiogenic factors

Biochimica et Biophysica Acta - Reviews on Cancer, ISSN: 0304419X

Napoleone Ferrara; Jennifer Lecouter; Rui Lin; Franklin V. Peale Jr.

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March 1, 2004

Dynamic Expression of Lef/Tcf Family Members and β-Catenin during Chick Gastrulation, Neurulation, and Early Limb Development

Developmental Dynamics, ISSN: 10588388

Maike Schmidt; Margaret Patterson; Elizabeth Farrell; Andrea Münsterberg

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March 1, 2004

Gata2 specifies serotonergic neurons downstream of sonic hedgehog

Development (Cambridge), ISSN: 09501991

Sarah E. Craven; Kim-Chew Lim; Weilan Ye; James Douglas Engel; Frederic J. De Sauvage; Arnon Rosental

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March 1, 2004

Computational and experimental studies on Human Misshapen/NIK-related kinase MINK-1

Current Medicinal Chemistry, ISSN: 09298673

Kunbin Qu; Yanmei Lu; Nan Lin; Rajinder Singh; Xiang Xu; Donald G. Payan; Dong Xu

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March 1, 2004

Compromised Humoral and Delayed-Type Hypersensitivity Responses in IL-23-Deficient Mice

Journal of Immunology, ISSN: 00221767

Nico Ghilardi; Noelyn Kljavin; Qi Chen; Sophie Lucas; Austin L. Gurney; Frederic J. De Sauvage

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March 1, 2004

Commercial manufacturing scale formulation and analytical characterization of therapeutic recombinant antibodies

Drug Development Research, ISSN: 02724391

Reed J. Harris; Reven J. Shire; Charles Winter

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March 1, 2004

Association between HER-2/neu and Vascular Endothelial Growth Factor Expression Predicts Clinical Outcome in Primary Breast Cancer Patients

Clinical Cancer Research, ISSN: 10780432

Gottfried E. Konecny; Meng; Untch; Wang; Ingo Bauerfeind; Melinda Epstein; Petra Stieber; Jean-Michel Vernes; Johnny Gutierrez; Kyu Hong; Malgorzata Beryt; Hermann Hepp; Dennis J. Slamon; Pegram

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March 1, 2004

Application of Frequency-Modulated Spectroscopy in Vacuum Seal Integrity Testing of Lyophilized Biological Products

PDA Journal of Pharmaceutical Science and Technology, ISSN: 10797440

Tanya P. Lin; Chung C. Hsu; Bruce Kabakoff; Thomas W. Patapoff

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March 1, 2004

A complementary transposon tool kit for Drosophila melanogaster using P and piggyBac

Nature Genetics, ISSN: 10614036

Stephen T. Thibault; Matthew A. Singer; Wesley Y. Miyazaki; Brett Milash; Nicholas A. Dompe; Carol M. Singh; Ross Buchholz; Madelyn Demsky; Robert Fawcett; Helen L. Francis-Lang; Lisa Ryner; Lai Man Cheung; Angela Chong; Cathy Erickson; William W. Fisher; Kimberly Greer; Stephanie R. Hartouni; Elizabeth Howie; Lakshmi Jakkula; Daniel Joo; Keith Killpack; Alex Laufer; Julie Mazzotta; Ronald D. Smith; Lynn M. Stevens; Christiana Stuber; Lory R. Tan; Richard Ventura; Alesa Woo; Irena Zakrajsek; Lora Zhao; Feng Chen; Candace Swimmer; Casey Kopczynski; Geoffrey Duyk; Margaret L. Winberg; Jonathan Margolis

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February 27, 2004

Human De-Etiolated-Regulates c-Jun by Assembling a CUL4A Ubiquitin Ligase

Science, ISSN: 00368075

Ingrid E. Wertz; Karen M. O'Rourke; Zemin Zhang; David Dornan; David Arnott; Raymond J. Deshaies; Vishva M. Dixit

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February 27, 2004

Definition of the Consensus Motif Recognized by γ-Adaptin Ear Domains

Journal of Biological Chemistry, ISSN: 00219258

Rafael Mattera; Brigitte Ritter; Sachdev S. Sidhu; Peter S. McPherson; Juan S. Bonifacino

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February 26, 2004

Gene expression profiling of human colon xenograft tumors following treatment with SU11248, a multitargeted tyrosine kinase inhibitor

Oncogene, ISSN: 09509232

Alyssa M. Morimoto; Nguyen Tan; Kristina West; McArthur; Guy C. Toner; William C. Manning; Beverly D. Smolich; Julie M. Cherrington

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February 24, 2004

Recurrent events analysis in the presence of time-dependent covariates and dependent censoring

Journal of the Royal Statistical Society. Series B: Statistical Methodology, ISSN: 13697412

Maja Miloslavsky; Sündüz Keleş; Mark J. van der Laan; Butler

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February 20, 2004

Engineered Human IgG Antibodies with Longer Serum Half-lives in Primates

Journal of Biological Chemistry, ISSN: 00219258

Paul R. Hinton; Mary G. Johlfs; Joanna M. Xiong; Kelly Hanestad; Kelly C. Ong; Chuck Bullock; Steve Keller; Meina Tao Tang; J. Yun Tso; Max Vásquez; Naoya Tsurushita

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February 20, 2004

Tumor Necrosis Factor: An Apoptosis JuNKie?

Cell, ISSN: 00928674

Eugene Varfolomeev; Avi Ashkenazi

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February 15, 2004

Combining Liquid Chromatography with MALDI Mass Spectrometry Using a Heated Droplet Interface

Analytical Chemistry, ISSN: 00032700

Boyan Zhang; Chris McDonald; Liang Li

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February 10, 2004

Similar Molecular Interactions of Factor VII and Factor VIIa with the Tissue Factor Region that Allosterically Regulates Enzyme Activity

Biochemistry, ISSN: 00062960

Robert F. Kelley; Yang; Eigenbrot; Paul Moran; Peek; Michael T. Lipari; Daniel Kirchhofer

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February 9, 2004

Vancomycin disulfide derivatives as antibacterial agents

Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X

YongQi Mu; Matthew B. Nodwell; John Pace; Jeng-Pyng Shaw; J. Kevin Judice

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February 1, 2004

Kinase RIP3 Is Dispensable for Normal NF-κBs, Signaling by the B-Cell and T-Cell Receptors, Tumor Necrosis Factor Receptor 1, and Toll-Like Receptors 2 and 4

Molecular and Cellular Biology, ISSN: 02707306

Kim Newton; Xiaoqing Sun; Vishva M. Dixit

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February 1, 2004

APRIL-Deficient Mice Have Normal Immune System Development

Molecular and Cellular Biology, ISSN: 02707306

Eugene Varfolomeev; Frank C. Kischkel; Flavius Martin; Dhaya Seshasayee; Hua Wang; David Lawrence; Christine Olsson; Lucrece Tom; Sharon Erickson; French; Peter Schow; Iqbal S. Grewal; Avi Ashkenazi

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February 1, 2004

Role of L-selectin in the development of autoimmune diabetes in non-obese diabetic mice

International Immunology, ISSN: 09538178

Conchi Mora; Iqbal S. Grewal; F. Susan Wong; Richard A. Flavell

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February 1, 2004

Myodegeneration in EDA-A2 Transgenic Mice Is Prevented by XEDAR Deficiency

Molecular and Cellular Biology, ISSN: 02707306

Kim Newton; French; Minhong Yan; Gretchen D. Frantz; Vishva M. Dixit

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February 1, 2004

EphB2 as a Therapeutic Antibody Drug Target for the Treatment of Colorectal Cancer

Cancer Research, ISSN: 00085472

Mao; Luis; Ross; Johnny Silva; Christine Tan; Crowley; Clarissa Chui; Gretchen Franz; Peter Senter; Koeppen; Paul G. Polakis

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February 1, 2004

Endocytosed Cation-Independent Mannose 6-Phosphate Receptor Traffics via the Endocytic Recycling Compartment en Route to the trans-Golgi Network and a Subpopulation of Late Endosomes

Molecular Biology of the Cell, ISSN: 10591524

Sharron X. Lin; William Mallet; Amy Y. Huang; Frederick R. Maxfield

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January 30, 2004

PEST Domain-Enriched Tyrosine Phosphatase (PEP) Regulation of Effector/Memory T Cells

Science, ISSN: 00368075

Kiminori Hasegawa; Flavius Martin; Guangming Huang; Daniel B. Tumas; Laurie Diehl; Andrew A. Chan

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January 29, 2004

Multiple G-protein-coupled receptor signals converge on the epidermal growth factor receptor to promote migration and invasion

Oncogene, ISSN: 09509232

Beatrix Schäfer; Andreas Gschwind; Axel Ullrich

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January 26, 2004

Quinine/Quinidine-Induced Thrombocytopenia: A Great Imitator

Archives of Internal Medicine, ISSN: 00039926

Josina C. Reddy; Shuman; Richard H. Aster

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January 23, 2004

Factorial screening of antibody purification processes using three chromatography steps without protein A

Journal of Chromatography A, ISSN: 00219673

Deborah K. Follman; Fahrner

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January 22, 2004

Recordings from Single Neocortical Nerve Terminals Reveal a Nonselective Cation Channel Activated by Decreases in Extracellular Calcium

Neuron, ISSN: 08966273

Stephen M. Smith; Jeremy B. Bergsman; Nobutoshi C. Harata; Richard H. Scheller; Richard W. Tsien

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January 15, 2004

Alteplase for Treatment of Occluded Peripherally Inserted Central Catheters: Safety and Efficacy in 240 Patients

Journal of Vascular and Interventional Radiology, ISSN: 10510443

Rita Ng; Xin Li; Tri Tu; Charles P. Semba

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January 9, 2004

Rip2 Participates in Bcl10 Signaling and T-cell Receptor-mediated NF-κB Activation

Journal of Biological Chemistry, ISSN: 00219258

Astrid A. Ruefli-Brasse; Wyne P. Lee; Stephen D. Hurst; Vishva M. Dixit

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January 8, 2004

Bcl10 activates the NF-κB pathway through ubiquitination of NEMO

Nature, ISSN: 00280836

Honglin Zhou; Ingrid E. Wertz; Karen M. O'Rourke; Ultsch; Somasekar Seshagiri; Mike Eby; Wei Xiao; Vishva M. Dixit

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January 2, 2004

Structure-activity relationships by mass spectrometry: Identification of novel MMP-3 inhibitors

Bioorganic and Medicinal Chemistry, ISSN: 09680896

Denise A. Ockey; Jennafer Dotson; Martin Struble; Stults; James H. Bourell; Clark; Thomas Gadek

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January 1, 2004

A Substrate-phage approach for investigating caspase specificity

Protein Journal, ISSN: 18758355 15723887

Samantha Lien; Richard Pastor; Daniel P. Sutherlin; Henry B. Lowman

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January 1, 2004

Inhibitors of histone deacetylases promote hematopoietic stem cell self-renewal

Cytotherapy, ISSN: 14653249

Judy Young; Wu; Hansteen; Du; Sambucetti; Remiszewski; O'Farrell; Hill; Lavau; Lesley J. Murray

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January 1, 2004

Mycobacterium marinum: The generalization and specialization of a pathogenic mycobacterium

Microbes and Infection, ISSN: 1769714X 12864579

Luisa M. Stamm; Eric J. Brown

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January 1, 2004

Quality Assurance Practices for Pharmaceutical Industry-Based Drug Information Departments: A Review and Case Study

Therapeutic Innovation and Regulatory Science, ISSN: 21684790

Stacey M. Fung; Joyce Serrano Martin

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January 1, 2004

Bevacizumab (Avastin).

Clinical journal of oncology nursing, ISSN: 10921095

Gena Middleton; Denise V Lapka

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January 1, 2004

Re: Catheter-directed Thrombolytic Therapy for Limb Ischemia: Current Status and Controversies [1]

Journal of Vascular and Interventional Radiology, ISSN: 10510443

Charles P. Semba; Iris Tam; Martha Blaney

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January 1, 2004

Topical vascular endothelial growth factor accelerates diabetic wound healing through increased angiogenesis and by mobilizing and recruiting bone marrow-derived cells

American Journal of Pathology, ISSN: 00029440

Robert D. Galiano; Oren M. Tepper; Catherine R. Pelo; Kirit A. Bhatt; Matthew Callaghan; Nicholas Bastidas; Bunting; Hope Steinmetz; Geoffrey C. Gurtner

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January 1, 2004

From functional genomics to target validation: The quest for better drugs

Drug Discovery Today: TARGETS, ISSN: 17418372

Jean-Philippe Stephan

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January 1, 2004

A blockade in Wnt signaling is activated following the differentiation of F9 teratocarcinoma cells

Experimental Cell Research, ISSN: 00144827

Sayumi Shibamoto; Jane Winer; Mickey P. Williams; Paul G. Polakis

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