Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 11251 - 11300 OF 15583 RESULTS

January 1, 2003

POPing the fire into the pyrin?

Biochemical Journal, ISSN: 14708728

Sanjeev Mariathasan; Domagoj Vucic

January 1, 2003

Toll-like receptor 2 ligands as adjuvants for human Th1 responses

Journal of Immunology, ISSN: 00221767

Peter A. Sieling; Woosin Chung; Baochau T. Duong; Godowski; Robert L. Modlin

January 1, 2003

Functional genomics of intracellular peptide recognition domains with combinatorial biology methods

Current Opinion in Chemical Biology, ISSN: 13675931

Sachdev S. Sidhu; Gary D. Bader; Charles Boone

January 1, 2003

Factors influencing outcomes in cystic fibrosis: A center-based analysis

Chest, ISSN: 00123692

Charles A. Johnson; Butler; Michael W. Konstan; Morgan; Mary Ellen Wohl

January 1, 2003

Reactive quinones differentially regulate SAPK/JNK and p38/mHOG stress kinases

Antioxidants and Redox Signaling, ISSN: 15230864

Krista L. Seanor; Janet V. Cross; Suzanne M. Nguyen; Minhong Yan; Dennis J. Templeton

January 1, 2003

DNA methylation, a biomarker for colorectal cancer: Implications for screening and pathological utility

Annals of the New York Academy of Sciences, ISSN: 00778923

Adrian M. Jubb; Philip Quirke; Adam J. Oates

January 1, 2003

Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases

Journal of Clinical Investigation, ISSN: 00219738

Vera Eremina; Manish Sood; Jody Haigh; Andras Nagy; Ginette Lajoie; Napoleone Ferrara; Hans-Peter Gerber; Yamato Kikkawa; Jeffrey H. Miner; Susan E. Quaggin

January 1, 2003

Use of process data to assess chromatographic performance in production-scale protein purification columns

Biotechnology Progress, ISSN: 87567938

Tina M. Larson; Jeff Davis; Harry Lam; Cacia

January 1, 2003

Neutralizing interferon alpha as a therapeutic approach to autoimmune diseases

Cytokine and Growth Factor Reviews, ISSN: 13596101

Stewart

January 1, 2003

Regulation of thymocyte development: Only the meek survive

Current Opinion in Immunology, ISSN: 09527915

Paul E. Love; Andrew A. Chan

January 1, 2003

Effect of Anti-CD20 Monoclonal Antibody, Rituxan, on Cynomolgus Monkey and Human B Cells in a Whole Blood Matrix

Cytometry Part A, ISSN: 15524922

Yulia Vugmeyster; Howell; Anahid Bakshl; Flores; Eleanor Canova-Davis

January 1, 2003

An antibody to VEGF upregulates factor VIII via interleukin-1 in activated adrenal cortex-derived capillary endothelial cells

International Immunopharmacology, ISSN: 15675769

Wenlu Li; Gilbert-Andre Keller

January 1, 2003

Preclinical studies with erlotinib (Tarceva)

Seminars in Oncology, ISSN: 00937754

Robert W. Akita; Mark X. Sliwkowski

January 1, 2003

Apo2L/TRAIL: Apoptosis signaling, biology, and potential for cancer therapy

Cytokine and Growth Factor Reviews, ISSN: 13596101

Alexandru Almasan; Avi Ashkenazi

January 1, 2003

Trends in cancer therapy: Role of monoclonal antibodies

Seminars in Oncology Nursing, ISSN: 07492081

Kristi V. Schmidt; Barbara A. Wood

January 1, 2003

Molecular targets in cancer therapy

Seminars in Oncology Nursing, ISSN: 07492081

Danielle M. Gale

January 1, 2003

Characterization of gentamicin-resistant Mycoplasma hyorhinis

Biologicals, ISSN: 10451056

Arit D. Idowu; Michelle C. Celones; Amparo E. Salgado; Kristine M. Marquez; Nancy Pleibel

January 1, 2003

Protein identification: The origins of peptide mass fingerprinting

Journal of the American Society for Mass Spectrometry, ISSN: 10440305

William J. Henzel; Colin K. Watanabe; Stults

January 1, 2003

Pharmacodynamics of omalizumab: Implications for optimised dosing strategies and clinical efficacy in the treatment of allergic asthma

Current Medical Research and Opinion, ISSN: 03007995

Guenther Hochhaus; Laurence Brookman; Howard Fox; Charles A. Johnson; Matthews; Song Ren; Yamo Deniz

January 1, 2003

Trastuzumab and Cardiac Dysfunction: Update on Preclinical Studies

Seminars in Oncology, ISSN: 00937754

Pam Klein; Noel Dybdal

January 1, 2003

Differential in vivo effects of rituximab on two B-cell subsets in cynomolgus monkeys

International Immunopharmacology, ISSN: 15675769

Yulia Vugmeyster; Howell; Kathleen McKeever; Dan Combs; Eleanor Canova-Davis

January 1, 2003

Cyclic pressure modulates endothelial barrier function

Endothelium: Journal of Endothelial Cell Research, ISSN: 10623329

Hainsworth Y. Shin; Rena Bizios; Mary E. Gerritsen

January 1, 2003

Hepatocytes Express Nerve Growth Factor during Liver Injury: Evidence for Paracrine Regulation of Hepatic Stellate Cell Apoptosis

American Journal of Pathology, ISSN: 00029440

Fiona Oakley; Nathan Trim; Christothea M. Constandinou; Weilan Ye; Gray; Gretchen D. Frantz; Kenneth J. Hillan; Tim Kendall; R. Christopher Benyon; Derek A. Mann; John P. Iredale

January 1, 2003

B cell therapy for rheumatoid arthritis: The rituximab (anti-CD20) experience

Annals of the Rheumatic Diseases, ISSN: 00034967

Tim Shaw; Joanne M. Quan; Totoritis

January 1, 2003

Is there evidence of implicit exclusion criteria for elderly subjects in randomized trials? Evidence from the GUSTO-1 study

American Heart Journal, ISSN: 00028703

Harlan M. Krumholz; Cary P. Gross; Eric D. Peterson; Hal V. Barron; Martha J. Radford; Lori Parsons; Nathan R. Every

January 1, 2003

Development of a Patient Recruitment Program for Phase 2 Trials in a Biotechnology Company

Drug Information Journal, ISSN: 00928615

Stacey M. Fung; Ellen Suen; Herbert B. Lee

January 1, 2003

EphA/ephrin-A interactions regulate epileptogenesis and activity-dependent axonal sprouting in adult rats

Molecular and Cellular Neuroscience, ISSN: 10447431

Xu; Li; Brown; Gerlai; Fahnestock; Racine

January 1, 2003

EGFR signal transactivation in cancer cells

Biochemical Society Transactions, ISSN: 03005127

Oliver M. Fischer; Stefan Hart; Andreas Gschwind; Axel Ullrich

January 1, 2003

Mechanisms of aggregate formation and carbohydrate excipient stabilization of lyophilized humanized monoclonal antibody formulations

AAPS Journal, ISSN: 15507416

Andya; Chung C. Hsu; Steven J. Shire

January 1, 2003

Tissue microarrays in drug discovery

Nature Reviews Drug Discovery, ISSN: 14741776

Guido Sauter; Ronald Simon; Kenneth J. Hillan

January 1, 2003

The Crystal Structures of EDA-A1 and EDA-A2: Splice Variants with Distinct Receptor Specificity

Structure, ISSN: 09692126

Sarah G. Hymowitz; Deanne M. Compaan; Minhong Yan; Heidi J. A. Wallweber; Vishva M. Dixit; Melissa A. Starovasnik; De Vos

January 1, 2003

An overview of quantitative PCR assays for biologicals: quality and safety evaluation.

Developments in Biologicals, ISSN: 14246074

Yuan Xu; Kurt Brorson

January 1, 2003

Neutralization of Western diet inhibits bone resorption independently of K intake and reduces cortisol secretion in humans

American Journal of Physiology - Renal Physiology, ISSN: 15221466 1931857X

Marc Maurer; Walter Riesen; Juergen Muser; Henry N. Hulter; Reto Krapf

December 27, 2002

Cdc42 and Rac1 regulate late events in Salmonella typhimurium-induced interleukin-8 secretion from polarized epithelial cells

Journal of Biological Chemistry, ISSN: 00219258

Michael E. Hobert; Kara A. Sands; Mrsny; James L. Madara

December 15, 2002

α4 integrins and vascular cell adhesion molecule-1 play a role in sympathetic innervation of the heart

Journal of Neuroscience, ISSN: 02706474

Kevin L. Wingerd; Nichol L. Goodman; Jason W. Tresser; Matthew M. Smail; Sergiu T. Leu; Steven J. Rohan; Jan L. Pring; Jackson; Dennis O. Clegg

December 10, 2002

Use of emergency medical services in acute myocardial infarction and subsequent quality of care: Observations from the national registry of myocardial infarction 2

Circulation, ISSN: 00097322

John G. Canto; Robert J. Zalenski; Joseph P. Ornato; William J. Rogers; Calarina I. Kiefe; David J. Magid; Michael G. Shlipak; Paul D. Frederick; Costas Lambrew; Katherine A. Littrell; Hal V. Barron

December 6, 2002

Unusual proteolytic activation of pro-hepatocyte growth factor by plasma kallikrein and coagulation factor XIa

Journal of Biological Chemistry, ISSN: 00219258

Peek; Paul Moran; Nerissa Mendoza; Dineli Wickramasinghe; Daniel Kirchhofer

December 2, 2002

BLNK: Molecular scaffolding through 'cis'-mediated organization of signaling proteins

EMBO Journal, ISSN: 02614189

Christopher Chiu; Mark Dalton; Masamichi Ishiai; Tomohiro Kurosaki; Andrew A. Chan

December 2, 2002

Hippocampal LTP and memory in mouse strains: Is there evidence for a causal relationship?

Hippocampus, ISSN: 10509631

Gerlai

December 1, 2002

Natural heterogeneity in the constant regions of human immunoglobulins

Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics,

Chin; Bao-Jen Shyong; Viswanatham Katta

December 1, 2002

A comparison of shotgun sequencing and 2-D electrophoresis for the identification of proteins in complex mixtures: Escherichia coli whole cell lysate

Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics,

Stults; David Arnott; Kathy L. O'Connell; G. Tony Moreno; Kathleen M. Champion; Shiaw-Lin Wu; Paul Shieh; William S. Hancock

December 1, 2002

Rapid methods for confirmation of suspected post-translational modifications

Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics,

Kathy L. O'Connell; Jianping Yin; Melissa A. Starovasnik; Ying Li; Lynne Giere; Crowley; Anita Izrael-Tomasevic; Stults

December 1, 2002

A generic mass spectrometric method for the quantitation of monoclonal antibody drugs in serum

Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics,

Victor Ling; Bao-Jen Shyong; Bryan Sandlund; Quarmby; Gary Tanuguchi; Jonathan McNally; Van Chen

December 1, 2002

Pharmacokinetics and pharmacodynamics of tenecteplase in fibrinolytic therapy of acute myocardial infarction

Clinical Pharmacokinetics, ISSN: 03125963

Tanswell; Modi; Dan Combs; Danays

December 1, 2002

Treatment of occluded central venous catheters with alteplase: Results in 1,064 patients

Journal of Vascular and Interventional Radiology, ISSN: 10510443

Charles P. Semba; Steven R. Deitcher; Xin Li; Laura Resnansky; Tri Tu; Edward R. McCluskey

December 1, 2002

Characterization of the disulfide bond pattern in β-1,4- galactosyltransferase 7 by LC/ESI-MS/MS

Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics,

Corpuz; Richard L. Vandlen; Ten-Yang Yen; Bruce A. Macher

December 1, 2002

Investigation of the solvent and counter-ion stabilization of multiply charged anions in the gas phase

Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics,

Xue-Bin Wang; Xin Yang; Lai-Sheng Wang; John B. Nicholas

December 1, 2002

Characterization and monitoring of monoclonal antibody variants in process control

Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics,

Bao-Jen Shyong; Eng; Galahad Deperalta; Victor Ling

December 1, 2002

pKa, MM, and QM studies of mechanisms of β-lactamases and penicillin-binding proteins: Acylation step

Journal of Computational Chemistry, ISSN: 01928651

Irina Massova; Peter A. Kollman

December 1, 2002

Dornase alfa in young patients with cystic fibrosis [1] (multiple letters)

Journal of Pediatrics, ISSN: 00223476

Edward R. Carter; Joanne M. Quan

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