Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 11351 - 11400 OF 15701 RESULTS

January 1, 2003

Phase i I, randomized trial comparing bevacizumab plus fluorouracil (FU)/Leucovorin (LV) with FU/LV alone in patients with metastatic colorectal cancer

Journal of Clinical Oncology, ISSN: 15277755 0732183X

Fairooz F. Kabbinavar; Herbert Hurwitz; Louis Fehrenbacher; Neal J. Meropol; Novotny; Lieberman; Susan Griffing; Emily Bergsland

January 1, 2003

Branching out: A molecular fingerprint of endothelial differentiation into tube-like structures generated by affymetrix oligonucleotide arrays

Microcirculation, ISSN: 10739688

Mary E. Gerritsen; Robert Soriano; Suya Yang; Constance Zlot; Gladys S. Ingle; Toy; P. Mickey Williams

January 1, 2003

Therapeutic peptides

Trends in Biotechnology, ISSN: 01677799

Samantha Lien; Henry B. Lowman

January 1, 2003

Immunofluorescent labeling of cancer marker Her2 and other cellular targets with semiconductor quantum dots

Nature Biotechnology, ISSN: 10870156

Xingyong Wu; Hongjian Liu; Jianquan Liu; Kari N. Haley; Joseph A. Treadway; J. Peter Larson; Nianfeng Ge; Franklin V. Peale Jr.; Marcel P. Bruchez

January 1, 2003

Small molecule antagonists of proteins

Biochemical Pharmacology, ISSN: 00062952

Thomas Gadek; John B. Nicholas

January 1, 2003

Guidelines for the diagnosis and therapy of adult myelodysplastic syndromes

British Journal of Haematology, ISSN: 00071048

David Bowen; Dominic Culligan; Simon Jowitt; Stephen Kelsey; Ghulam Mufti; David Oscier; Jane Parker

January 1, 2003

Foreword

Microcirculation, ISSN: 10739688

Mary E. Gerritsen

January 1, 2003

NMR structural analysis of vascular endothelial growth factor in complex with a phage-derived peptide antagonist

Spectroscopy, ISSN: 07124813

Borlan Pan; Wayne J. Fairbrother

January 1, 2003

Apo2L/TRAIL and its death and decoy receptors

Cell Death and Differentiation, ISSN: 13509047

Heidi LeBlanc; Avi Ashkenazi

January 1, 2003

Zinc finger protein too few controls the development of monoaminergic neurons

Nature Neuroscience, ISSN: 10976256

Gil Levkowitz; Jörg Zeller; Howard I. Sirotkin; French; Sarah Schilbach; Hisashi Hashimoto; Masahiko Hibi; William S. Talbot; Rosenthal

January 1, 2003

β-hairpin polypeptides by design and selection

Spectroscopy, ISSN: 07124813

Nicholas J. Skelton; Tamas Blandl; Russell; Melissa A. Starovasnik; Andrea G Cochran

January 1, 2003

VEGF-C mediates cyclic pressure-induced endothelial cell proliferation

Physiological Genomics, ISSN: 15312267

Hainsworth Y. Shin; Michael L. Smith; Toy; P. Mickey Williams; Rena Bizios; Mary E. Gerritsen

January 1, 2003

Targeting VEGF ligands and receptors in cancer

Drug Discovery Today: TARGETS, ISSN: 17418372

Ajay K. Malik; Hans-Peter Gerber

January 1, 2003

The role of VEGF in normal and neoplastic hematopoiesis

Journal of Molecular Medicine, ISSN: 09462716

Hans-Peter Gerber; Napoleone Ferrara

January 1, 2003

Time course of skeletal muscle repair and gene expression following acute hind limb ischemia in mice

Physiological Genomics, ISSN: 15312267

Nicholas F. Paoni; Franklin V. Peale Jr.; Fay Wang; Errett-Baroncini; Hope Steinmetz; Toy; Wei Bai; P. Mickey Williams; Bunting; Mary E. Gerritsen; Powell-Braxton

January 1, 2003

The best of both worlds?: Potential of hybrid prospective/concurrent risk adjustment

Medical Care, ISSN: 00257079

R. Adams Dudley; Carol A. Medlin; Lisa B. Hammann; Miriam G. Cisternas; Richard Brand; Deborah J. Rennie; Harold S. Luft

January 1, 2003

Neutralization of Western diet inhibits bone resorption independently of K intake and reduces cortisol secretion in humans

American Journal of Physiology - Renal Physiology, ISSN: 03636127

Marc Maurer; Walter Riesen; Juergen Muser; Henry N. Hulter; Reto Krapf

January 1, 2003

Omalizumab, a recombinant humanized anti-IgE antibody, reduces asthma-related emergency room visits and hospitalizations in patients with allergic asthma

Journal of Allergy and Clinical Immunology, ISSN: 00916749

Jonathan Corren; Thomas B. Casale; Yamo Deniz; Ashby

January 1, 2003

POPing the fire into the pyrin?

Biochemical Journal, ISSN: 14708728

Sanjeev Mariathasan; Domagoj Vucic

January 1, 2003

Toll-like receptor 2 ligands as adjuvants for human Th1 responses

Journal of Immunology, ISSN: 00221767

Peter A. Sieling; Woosin Chung; Baochau T. Duong; Godowski; Robert L. Modlin

January 1, 2003

Functional genomics of intracellular peptide recognition domains with combinatorial biology methods

Current Opinion in Chemical Biology, ISSN: 13675931

Sachdev S. Sidhu; Gary D. Bader; Charles Boone

January 1, 2003

Factors influencing outcomes in cystic fibrosis: A center-based analysis

Chest, ISSN: 00123692

Charles A. Johnson; Butler; Michael W. Konstan; Morgan; Mary Ellen Wohl

January 1, 2003

Reactive quinones differentially regulate SAPK/JNK and p38/mHOG stress kinases

Antioxidants and Redox Signaling, ISSN: 15230864

Krista L. Seanor; Janet V. Cross; Suzanne M. Nguyen; Minhong Yan; Dennis J. Templeton

January 1, 2003

DNA methylation, a biomarker for colorectal cancer: Implications for screening and pathological utility

Annals of the New York Academy of Sciences, ISSN: 00778923

Adrian M. Jubb; Philip Quirke; Adam J. Oates

January 1, 2003

Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases

Journal of Clinical Investigation, ISSN: 00219738

Vera Eremina; Manish Sood; Jody Haigh; Andras Nagy; Ginette Lajoie; Napoleone Ferrara; Hans-Peter Gerber; Yamato Kikkawa; Jeffrey H. Miner; Susan E. Quaggin

January 1, 2003

Use of process data to assess chromatographic performance in production-scale protein purification columns

Biotechnology Progress, ISSN: 87567938

Tina M. Larson; Jeff Davis; Harry Lam; Cacia

January 1, 2003

Neutralizing interferon alpha as a therapeutic approach to autoimmune diseases

Cytokine and Growth Factor Reviews, ISSN: 13596101

Stewart

January 1, 2003

Regulation of thymocyte development: Only the meek survive

Current Opinion in Immunology, ISSN: 09527915

Paul E. Love; Andrew A. Chan

January 1, 2003

Effect of Anti-CD20 Monoclonal Antibody, Rituxan, on Cynomolgus Monkey and Human B Cells in a Whole Blood Matrix

Cytometry Part A, ISSN: 15524922

Yulia Vugmeyster; Howell; Anahid Bakshl; Flores; Eleanor Canova-Davis

January 1, 2003

An antibody to VEGF upregulates factor VIII via interleukin-1 in activated adrenal cortex-derived capillary endothelial cells

International Immunopharmacology, ISSN: 15675769

Wenlu Li; Gilbert-Andre Keller

January 1, 2003

Preclinical studies with erlotinib (Tarceva)

Seminars in Oncology, ISSN: 00937754

Robert W. Akita; Mark X. Sliwkowski

January 1, 2003

Apo2L/TRAIL: Apoptosis signaling, biology, and potential for cancer therapy

Cytokine and Growth Factor Reviews, ISSN: 13596101

Alexandru Almasan; Avi Ashkenazi

January 1, 2003

Trends in cancer therapy: Role of monoclonal antibodies

Seminars in Oncology Nursing, ISSN: 07492081

Kristi V. Schmidt; Barbara A. Wood

January 1, 2003

Molecular targets in cancer therapy

Seminars in Oncology Nursing, ISSN: 07492081

Danielle M. Gale

January 1, 2003

Characterization of gentamicin-resistant Mycoplasma hyorhinis

Biologicals, ISSN: 10451056

Arit D. Idowu; Michelle C. Celones; Amparo E. Salgado; Kristine M. Marquez; Nancy Pleibel

January 1, 2003

Protein identification: The origins of peptide mass fingerprinting

Journal of the American Society for Mass Spectrometry, ISSN: 10440305

William J. Henzel; Colin K. Watanabe; Stults

January 1, 2003

Pharmacodynamics of omalizumab: Implications for optimised dosing strategies and clinical efficacy in the treatment of allergic asthma

Current Medical Research and Opinion, ISSN: 03007995

Guenther Hochhaus; Laurence Brookman; Howard Fox; Charles A. Johnson; Matthews; Song Ren; Yamo Deniz

January 1, 2003

Trastuzumab and Cardiac Dysfunction: Update on Preclinical Studies

Seminars in Oncology, ISSN: 00937754

Pam Klein; Noel Dybdal

January 1, 2003

Differential in vivo effects of rituximab on two B-cell subsets in cynomolgus monkeys

International Immunopharmacology, ISSN: 15675769

Yulia Vugmeyster; Howell; Kathleen McKeever; Dan Combs; Eleanor Canova-Davis

January 1, 2003

Cyclic pressure modulates endothelial barrier function

Endothelium: Journal of Endothelial Cell Research, ISSN: 10623329

Hainsworth Y. Shin; Rena Bizios; Mary E. Gerritsen

January 1, 2003

Hepatocytes Express Nerve Growth Factor during Liver Injury: Evidence for Paracrine Regulation of Hepatic Stellate Cell Apoptosis

American Journal of Pathology, ISSN: 00029440

Fiona Oakley; Nathan Trim; Christothea M. Constandinou; Weilan Ye; Gray; Gretchen D. Frantz; Kenneth J. Hillan; Tim Kendall; R. Christopher Benyon; Derek A. Mann; John P. Iredale

January 1, 2003

B cell therapy for rheumatoid arthritis: The rituximab (anti-CD20) experience

Annals of the Rheumatic Diseases, ISSN: 00034967

Tim Shaw; Joanne M. Quan; Totoritis

January 1, 2003

Is there evidence of implicit exclusion criteria for elderly subjects in randomized trials? Evidence from the GUSTO-1 study

American Heart Journal, ISSN: 00028703

Harlan M. Krumholz; Cary P. Gross; Eric D. Peterson; Hal V. Barron; Martha J. Radford; Lori Parsons; Nathan R. Every

January 1, 2003

Development of a Patient Recruitment Program for Phase 2 Trials in a Biotechnology Company

Drug Information Journal, ISSN: 00928615

Stacey M. Fung; Ellen Suen; Herbert B. Lee

January 1, 2003

EphA/ephrin-A interactions regulate epileptogenesis and activity-dependent axonal sprouting in adult rats

Molecular and Cellular Neuroscience, ISSN: 10447431

Xu; Li; Brown; Gerlai; Fahnestock; Racine

January 1, 2003

EGFR signal transactivation in cancer cells

Biochemical Society Transactions, ISSN: 03005127

Oliver M. Fischer; Stefan Hart; Andreas Gschwind; Axel Ullrich

January 1, 2003

Mechanisms of aggregate formation and carbohydrate excipient stabilization of lyophilized humanized monoclonal antibody formulations

AAPS Journal, ISSN: 15507416

Andya; Chung C. Hsu; Steven J. Shire

January 1, 2003

Tissue microarrays in drug discovery

Nature Reviews Drug Discovery, ISSN: 14741776

Guido Sauter; Ronald Simon; Kenneth J. Hillan

January 1, 2003

The Crystal Structures of EDA-A1 and EDA-A2: Splice Variants with Distinct Receptor Specificity

Structure, ISSN: 09692126

Sarah G. Hymowitz; Deanne M. Compaan; Minhong Yan; Heidi J. A. Wallweber; Vishva M. Dixit; Melissa A. Starovasnik; De Vos

January 1, 2003

An overview of quantitative PCR assays for biologicals: quality and safety evaluation.

Developments in Biologicals, ISSN: 14246074

Yuan Xu; Kurt Brorson

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