Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 11401 - 11450 OF 15701 RESULTS

Neutralization of Western diet inhibits bone resorption independently of K intake and reduces cortisol secretion in humans
American Journal of Physiology - Renal Physiology, ISSN: 15221466 1931857X
Marc Maurer; Walter Riesen; Juergen Muser; Henry N. Hulter; Reto Krapf
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Cdc42 and Rac1 regulate late events in Salmonella typhimurium-induced interleukin-8 secretion from polarized epithelial cells
Journal of Biological Chemistry, ISSN: 00219258
Michael E. Hobert; Kara A. Sands; Mrsny; James L. Madara
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α4 integrins and vascular cell adhesion molecule-1 play a role in sympathetic innervation of the heart
Journal of Neuroscience, ISSN: 02706474
Kevin L. Wingerd; Nichol L. Goodman; Jason W. Tresser; Matthew M. Smail; Sergiu T. Leu; Steven J. Rohan; Jan L. Pring; Jackson; Dennis O. Clegg
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Use of emergency medical services in acute myocardial infarction and subsequent quality of care: Observations from the national registry of myocardial infarction 2
Circulation, ISSN: 00097322
John G. Canto; Robert J. Zalenski; Joseph P. Ornato; William J. Rogers; Calarina I. Kiefe; David J. Magid; Michael G. Shlipak; Paul D. Frederick; Costas Lambrew; Katherine A. Littrell; Hal V. Barron
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Unusual proteolytic activation of pro-hepatocyte growth factor by plasma kallikrein and coagulation factor XIa
Journal of Biological Chemistry, ISSN: 00219258
Peek; Paul Moran; Nerissa Mendoza; Dineli Wickramasinghe; Daniel Kirchhofer
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BLNK: Molecular scaffolding through 'cis'-mediated organization of signaling proteins
EMBO Journal, ISSN: 02614189
Christopher Chiu; Mark Dalton; Masamichi Ishiai; Tomohiro Kurosaki; Andrew A. Chan
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Hippocampal LTP and memory in mouse strains: Is there evidence for a causal relationship?
Hippocampus, ISSN: 10509631
Gerlai
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Natural heterogeneity in the constant regions of human immunoglobulins
Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics,
Chin; Bao-Jen Shyong; Viswanatham Katta
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A comparison of shotgun sequencing and 2-D electrophoresis for the identification of proteins in complex mixtures: Escherichia coli whole cell lysate
Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics,
Stults; David Arnott; Kathy L. O'Connell; G. Tony Moreno; Kathleen M. Champion; Shiaw-Lin Wu; Paul Shieh; William S. Hancock
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Rapid methods for confirmation of suspected post-translational modifications
Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics,
Kathy L. O'Connell; Jianping Yin; Melissa A. Starovasnik; Ying Li; Lynne Giere; Crowley; Anita Izrael-Tomasevic; Stults
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A generic mass spectrometric method for the quantitation of monoclonal antibody drugs in serum
Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics,
Victor Ling; Bao-Jen Shyong; Bryan Sandlund; Quarmby; Gary Tanuguchi; Jonathan McNally; Van Chen
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Pharmacokinetics and pharmacodynamics of tenecteplase in fibrinolytic therapy of acute myocardial infarction
Clinical Pharmacokinetics, ISSN: 03125963
Tanswell; Modi; Dan Combs; Danays
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Treatment of occluded central venous catheters with alteplase: Results in 1,064 patients
Journal of Vascular and Interventional Radiology, ISSN: 10510443
Charles P. Semba; Steven R. Deitcher; Xin Li; Laura Resnansky; Tri Tu; Edward R. McCluskey
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Characterization of the disulfide bond pattern in β-1,4- galactosyltransferase 7 by LC/ESI-MS/MS
Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics,
Corpuz; Richard L. Vandlen; Ten-Yang Yen; Bruce A. Macher
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Investigation of the solvent and counter-ion stabilization of multiply charged anions in the gas phase
Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics,
Xue-Bin Wang; Xin Yang; Lai-Sheng Wang; John B. Nicholas
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Characterization and monitoring of monoclonal antibody variants in process control
Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics,
Bao-Jen Shyong; Eng; Galahad Deperalta; Victor Ling
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pKa, MM, and QM studies of mechanisms of β-lactamases and penicillin-binding proteins: Acylation step
Journal of Computational Chemistry, ISSN: 01928651
Irina Massova; Peter A. Kollman
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Dornase alfa in young patients with cystic fibrosis [1] (multiple letters)
Journal of Pediatrics, ISSN: 00223476
Edward R. Carter; Joanne M. Quan
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Proteomics via multidimensional separations: Which dimensions to use?
Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics,
David Arnott; Kishiyama; Iman Mohtashemi; Wendy Shillinglaw; William J. Henzel; Stults
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Development and validation of a semi-automated 96-well protein precipitation method for quantification of plasma samples by LC/MS/MS
Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics,
Bilin Chou; Robin Robertson; Kamal Boora; John Hanson; Yang Wang; Cyrus Khojasteh-Bakht
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Model-based analysis of the pharmacokinetic interactions between ritonavir, nelfinavir, and saquinavir after simultaneous and staggered oral administration
Drug Metabolism and Disposition, ISSN: 00909556
Jian-Feng Lu; Terrence F. Blaschke; Charles Flexner; Susan L. Rosenkranz; Lewis B. Sheiner
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Endocrine gland vacular endothelial growth factor (EG-VEGF) and the hypothesis of tissue-specific regulation of angiogenesis
Endocrine Research, ISSN: 07435800
Napoleone Ferrara; Jennifer LeCounter
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Structure of the epidermal growth factor receptor kinase domain alone and in complex with a 4-anilinoquinazoline inhibitor
Journal of Biological Chemistry, ISSN: 00219258
Jennifer Stamos; Mark X. Sliwkowski; Eigenbrot
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NF-κB signaling: Many roads lead to Madrid
Cell, ISSN: 00928674
Vishva M. Dixit; Tak W. Mak
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Short constrained peptides that inhibit HIV-1 entry
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Samuel K. Sia; Peter A. Carr; Andrea G Cochran; Vladimir N. Malashkevich; Peter S. Kim
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Impact of cell culture process changes on endogenous retrovirus expression
Biotechnology and Bioengineering, ISSN: 00063592
Kurt Brorson; Christina De Wit; Elizabeth Hamilton; Mehnaz Mustafa; Patrick Swann; Robert Kiss; Ron Taticek; Gian D. Polastri; Kathryn Stein; Yuan Xu
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Complexation of VEGF with bevacizumab decreases VEGF clearance in rats
Pharmaceutical Research, ISSN: 07248741
Vanessa Hsei; Geralyn G. Deguzman; Nixon; Jacques Gaudreault
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A phase II study of thalidomide in advanced metastatic renal cell carcinoma
Investigational New Drugs, ISSN: 01676997
David R. Minor; Dana Monroe; Lisa A. Damico; Meng; Uma Suryadevara; Laurence Elias
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Phosphorylation and regulation of β-catenin by casein kinase Iε
Journal of Biochemistry, ISSN: 0021924X
Sakanaka
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Premenstrual dysphoric disorder is there an economic burden of Illness?
Medical Care, ISSN: 00257079
Chawla; Ralph Swindle; Stacey Long; Sean Kennedy; Barbara Sternfeld
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Solid–phase synthesis of dual α4β1#x03B1;4β7 integrin antagonists: Two scaffolds with overlapping pharmacophores
Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X
Georgette M. Castanedo; Fredrick C. Sailes; Dubree; John B. Nicholas; Lisa D. Caris; Clark; Keating; Beresini; Chiu; Fong; James C. Marsters Jr.; Jackson; Daniel P. Sutherlin
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Albumin affinity tags increase peptide half-life in vivo
Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X
Michael F. T. Koehler; Zobel; Beresini; Lisa D. Caris; Dan Combs; Paasch; Lazarus
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Solid–phase synthesis of dual α4β1#x03B1;4β7 integrin antagonists: Two scaffolds with overlapping pharmacophores
Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X
Georgette M. Castanedo; Fredrick C. Sailes; Dubree; John B. Nicholas; Lisa D. Caris; Clark; Keating; Beresini; Chiu; Sherman Fong; James C. Marsters Jr.; Jackson; Daniel P. Sutherlin
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Evaluation of HER-2/neu expression in prostatic adenocarcinoma: A request for a standardized, organ specific methodology
Cancer, ISSN: 0008543X
Katya M. Sanchez; Christopher J. Sweeney; Robert Mass; Michael O. Koch; George J. Eckert; William A. Geary; Lee Ann Baldridge; Shaobo Zhang; John N. Eble; Liang Cheng
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Distinct antigenic features of linear epitopes at the N-terminus and C-terminus of 65 kDa glutamic acid decarboxylase (GAD65): Implications for autoantigen modification during pathogenesis
Clinical and Experimental Immunology, ISSN: 00099104
Al-Bukhari; Radford; Bouras; Davenport; Trigwell; Bottazzo; Lai; Schwartz; Tighe; Todd
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Inhibition of ligand-mediated HER2 activation in androgen-independent prostate cancer
Cancer Research, ISSN: 00085472
Nerissa Mendoza; Gail L. Phillips; Johnny Silva; Ralph H. Schwall; Dineli Wickramasinghe
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Suppression of antibody production by TNF-related apoptosis-inducing ligand (TRAIL)
Cellular Immunology, ISSN: 00088749
Nobuhiko Kayagaki; Noriko Yamaguchi; Masaaki Abe; Sachiko Hirose; Toshikazu Shirai; Ko Okumura; Hideo Yagita
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VEGF and the quest for tumour angiogenesis factors
Nature Reviews Cancer, ISSN: 1474175X
Napoleone Ferrara
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Zmpste24 deficiency in mice causes spontaneous bone fractures, muscle weakness, and a prelamin A processing defect
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Martin O. Bergo; Bryant Gavino; Ross; Walter K. Schmidt; Christine Hong; Lonnie V. Kendall; Andreas Mohr; Margarita Meta; Harry Genant; Yebin Jiang; Erik R. Wisner; Nicholas Van Bruggen; Richard A. D. Carano; Susan Michaelis; Stephen M. Griffey; Stephen G. Young
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BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-κB2
Immunity, ISSN: 10747613
Nobuhiko Kayagaki; Minhong Yan; Dhaya Seshasayee; Hua Wang; Wyne P. Lee; French; Iqbal S. Grewal; Andrea G Cochran; Nathaniel C. Gordon; Jianping Yin; Melissa A. Starovasnik; Vishva M. Dixit
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The pharmacokinetic and pharmacodynamic characteristics of a long-acting growth hormone (GH) preparation (Nutropin Depot) in GH-deficient adults
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X
David Cook; Beverly M. K. Biller; Mary Lee Vance; Andrew R. Hoffman; Lawrence S. Phillips; Kathleen M. Ford; Benziger; Illeperuma; Sandra L. Blethen; Kenneth M. Attie; Dao; Reimann; Fielder
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Initial clinical results of tenecteplase (TNK) in catheter-directed thrombolytic therapy
Journal of Endovascular Therapy, ISSN: 15266028
Mahmood K Razavi; Humberto Wong; Stephen T. Kee; Daniel Y. Sze; Charles P. Semba; Michael D. Dake
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Albumin binding as a general strategy for improving the pharmacokinetics of proteins
Journal of Biological Chemistry, ISSN: 00219258
Dennis; Min Zhang; Meng; Miryam Kadkhodayan; Daniel Kirchhofer; Dan Combs; Lisa A. Damico
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Dissecting the oncogenic potential of Gli2: Deletion of an NH2-terminal fragment alters skin tumor phenotype
Cancer Research, ISSN: 00085472
Hong Sheng; Sara Goich; Aiqin Wang; Marina Grachtchouk; Lori Lowe; Rong Mo; Kui Lin; Frederic J. De Sauvage; Hiroshi Sasaki; Chi-chung Hui; Andrzej A. Dlugosz
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Theoretical and experimental investigation of the effect of proton transfer on the 27AI MAS NMR line shapes of zeolite-adsorbate complexes: An independent measure of solid acid strength
Journal of the American Chemical Society, ISSN: 00027863
Justin O. Ehresmann; Wei Wang; Bruno Herreros; Donat-Pierre Luigi; Venkatraman; Weiguo Song; John B. Nicholas; James F. Haw
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Molecular forms of NGF in human and rat neuropathic tissues: Decreased NGF precursor-like immunoreactivity in human diabetic skin
Journal of the Peripheral Nervous System, ISSN: 10859489
Yiangos Yiangou; Paul Facer; Sinicropi; Timothy J. Boucher; David L. H. Bennett; McMahon; Anand
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Proteomics in mixtures: Study results of ABRF-PRG02
Journal of Biomolecular Techniques, ISSN: 15240215 19434731
David Arnott; Mary Ann Gawinowicz; Raymond A. Grant; William Lane; Len C. Packman; Kaye D. Speicher; Kathryn Stone
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Challenging artificial genetic systems: Thymidine analogs with 5-position sulfur functionality
Nucleic Acids Research, ISSN: 03051048
Heike A. Held; Steven A. Benner
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Stanniocalcin 1 alters muscle and bone structure and function in transgenic mice
Endocrinology, ISSN: 00137227
Ellen H. Filvaroff; Guillet; Constance Zlot; Bao; Gladys S. Ingle; Hope Steinmetz; Hoeffel; Bunting; Ross; Richard A. D. Carano; Powell-Braxton; Graham F. Wagner; Eckert; Mary E. Gerritsen; French
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Effect of glycine on pH changes and protein stability during freeze-thawing in phosphate buffer systems
Journal of Pharmaceutical Sciences, ISSN: 00223549
Katherine A. Pikal-Cleland; Cleland; Thomas J. Anchordoquy; John F. Carpenter
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