Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 11451 - 11500 OF 15701 RESULTS

Endocrine gland-derived VEGF and the emerging hypothesis of organ-specific regulation of angiogenesis
Nature Medicine, ISSN: 10788956
Jennifer Lecouter; Rui Lin; Napoleone Ferrara
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The relationship of intracoronary stent placement following thrombolytic therapy to tissue level perfusion
Journal of Thrombosis and Thrombolysis, ISSN: 09295305
C.Michael Gibson; Frisch; Sabina A. Murphy; Steven G. Gourlay; Raymond J. Gibbons; Kenneth W. Baran; Michel Nguyen; Sebastian T. Palmeri; Hal V. Barron
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Efficient gene transduction to cultured hepatocytes by HIV-1 derived lentiviral vector
Transplantation Proceedings, ISSN: 00411345
Ohashi; Park; Ralph H. Schwall; Kay
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Sustained delivery of human growth hormone from a novel gel system: SABER™
Biomaterials, ISSN: 01429612
Okumu; Dao; Fielder; Noel Dybdal; Brooks; Samir Sane; Cleland
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Performance of a novel Viresolve NFR virus filter
Biotechnology Progress, ISSN: 87567938
Helene Brough; Chris Antoniou; Jeffrey Carter; Jocelyn Jakubik; Yuan Xu; Herbert Lutz
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Determination of residual moisture in lyophilized protein pharmaceuticals using a rapid and non-invasive method: Near infrared spectroscopy
PDA Journal of Pharmaceutical Science and Technology, ISSN: 10797440
Tanya P. Lin; Chung C. Hsu
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A target-mediated model to describe the pharmacokinetics and hemodynamic effects of recombinant human vascular endothelial growth factor in humans
Clinical Pharmacology and Therapeutics, ISSN: 00099236
Stephen M. Eppler; Dan Combs; Timothy D. Henry; John J. Lopez; Stephen G. Ellis; Joo-Hee Yi; Brian H. Annex; Edward R. McCluskey; Zioncheck
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Identification of a region within the ErbB2/HER2 intracellular domain that is necessary for ligand-independent association
Journal of Biological Chemistry, ISSN: 00219258
Elicia M. Penuel; Robert W. Akita; Mark X. Sliwkowski
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A direct role of the homeodomain proteins Phox2a/2b in noradrenaline neurotransmitter identity determination
Journal of Neurochemistry, ISSN: 00223042
Hyemyung Seo; Seok Jong Hong; Guo; Hee-Sun Kim; Chun-Hyung Kim; Dong-Youn Hwang; Ole Isacson; Rosenthal; Kwang-Soo Kim
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Amisyn, a novel syntaxin-binding protein that may regulate SNARE complex assembly
Journal of Biological Chemistry, ISSN: 00219258
Suzie J. Scales; Boris A. Hesser; Esteban S. Masuda; Richard H. Scheller
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Selective α4β7 integrin antagonists and their potential as antiinflammatory agents
Journal of Medicinal Chemistry, ISSN: 00222623
Dubree; Dean R. Artis; Georgette M. Castanedo; James C. Marsters Jr.; Daniel P. Sutherlin; Lisa D. Caris; Clark; Keating; Beresini; Chiu; Fong; Henry B. Lowman; Nicholas J. Skelton; Jackson
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Selective α4β7 integrin antagonists and their potential as antiinflammatory agents
Journal of Medicinal Chemistry, ISSN: 00222623
Dubree; Dean R. Artis; Georgette M. Castanedo; James C. Marsters Jr.; Daniel P. Sutherlin; Lisa D. Caris; Clark; Keating; Beresini; Chiu; Sherman Fong; Henry B. Lowman; Nicholas J. Skelton; Jackson
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Lack of fucose on human IgG1 N-linked oligosaccharide improves binding to human FcγRIII and antibody-dependent cellular toxicity
Journal of Biological Chemistry, ISSN: 00219258
Robert L. Shields; Lai; Rodney Keck; O'Connell; Kyu Hong; Meng; Weikert; Presta
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Vascular endothelial growth factor stimulates bone repair by promoting angiogenesis and bone turnover
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
John Street; Bao; Leo Deguzman; Bunting; Franklin V. Peale Jr.; Napoleone Ferrara; Hope Steinmetz; Hoeffel; Cleland; Daugherty; Nicholas Van Bruggen; H. Paul Redmond; Richard A. D. Carano; Ellen H. Filvaroff
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Casein kinase 1: A Wnt'er of disconnect
Current Biology, ISSN: 09609822
Paul G. Polakis
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Truncated, inactive N-acetylglucosaminyltransferase III (GlcNAc-TIII) induces neurological and other traits absent in mice that lack GlcNAc-TIII
Journal of Biological Chemistry, ISSN: 00219258
Riddhi Bhattacharyya; Mantu Bhaumik; T. Shantha Raju; Pamela Stanley
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Effects on quality of life of combined trastuzumab and chemotherapy in women with metastatic breast cancer
Journal of Clinical Oncology, ISSN: 0732183X
David Osoba; Dennis J. Slamon; Michael Burchmore; Maureen Murphy
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Three-dimensional structure of the amino-terminal domain of syntaxin 6, a SNAP-25 C homolog
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Kira M. S. Misura; Jason Bock; Lino C. Gonzalez Jr.; Richard H. Scheller; William I. Weis
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Regulation of endothelial cell proliferation and apoptosis by cyclic pressure
Annals of Biomedical Engineering, ISSN: 00906964
Hainsworth Y. Shin; Mary E. Gerritsen; Rena Bizios
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A risk model derived from the National Registry of Myocardial Infarction 2 database for predicting mortality after coronary artery bypass grafting during acute myocardial infarction
American Journal of Cardiology, ISSN: 00029149
Jonathan G Zaroff; Dante G DiTommaso; Hal V. Barron
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Synthesis of the heptamethylbenzenium cation in zeolite-β: In situ NMR and theory
Catalysis Letters, ISSN: 1011372X
Weiguo Song; John B. Nicholas; Alain Sassi; James F. Haw
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Validation of large-scale chromatographic processes, Part 2: Results from the case study of neuleze capture on Macroprep High-S
BioPharm, ISSN: 10408304
Timothy N. Breece; Ellen Gilkerson; Charles H. Schmelzer
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Quantitative evaluation of proteins in one- and two-dimensional polyacrylamide gels using a fluorescent stain
Electrophoresis, ISSN: 01730835
Julie C. Nishihara; Kathleen M. Champion
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VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism
Nature, ISSN: 00280836
Hans-Peter Gerber; Ajay K. Malik; Gregg Solar; Sherman; Xiao Huan Liang; Meng; Kyu Hong; James C. Marsters Jr.; Napoleone Ferrara
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KDR (VEGF receptor 2) is the major mediator for the hypotensive effect of VEGF
Hypertension, ISSN: 0194911X
Bing Li; Annie Ogasawara; Renhui Yang; Wei Wei; Guo-Wei He; Zioncheck; Bunting; De Vos; Hongkui Jin
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Alpha 4 integrin antagonists
Current Pharmaceutical Design, ISSN: 13816128
Jackson
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Structure, function, and activation of coagulation factor VII
Current Protein and Peptide Science, ISSN: 13892037
Eigenbrot
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Enhanced tumor killing by Apo2L/TRAIL and CPT-11 co-treatment is associated with p21 cleavage and differential regulation of Apo2L/TRAIL ligand and its receptors
Oncogene, ISSN: 09509232
Hong Xiang; Judy Fox; Klara Totpal; Mina Aikawa; Kelly J. DuPree; Sinicropi; John Lowe; Escandon
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Endosperm-specific expression of green fluorescent protein driven by the hordein promoter is stably inherited in transgenic barley (Hordeum vulgare) plants
Physiologia Plantarum, ISSN: 00319317
Myeong-Je Cho; Hae-Woon Choi; Jiang; Chi D. Ha; Peggy G. Lemaux
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Analysis methods of polysorbate 20: A new method to assess the stability of polysorbate 20 and established methods that may overlook degraded polysorbate 20
Pharmaceutical Research, ISSN: 07248741
Mehrnaz Khossravi; Kao; Mrsny; Sweeney
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Refinement of the solution structure of the heparin-binding domain of vascular endothelial growth factor using residual dipolar couplings
Journal of Biomolecular NMR, ISSN: 09252738
Melissa E. Stauffer; Nicholas J. Skelton; Wayne J. Fairbrother
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Hospital transfer of patients with acute myocardial infarction: The effects of age, race, and insurance type
American Journal of Medicine, ISSN: 00029343
Jerry H. Gurwitz; Robert J. Goldberg; Judith A. Malmgren; Hal V. Barron; Alan J. Tiefenbrunn; Paul D. Frederick; Joel M. Gore
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Assessing insulin resistance: Application of a fasting glucose to insulin ratio in growth hormone-treated children
Hormone Research, ISSN: 03010163
Tania S. Burgert; Patricia M. Vuguin; Dimartino-Nardi; Kenneth M. Attie; Saenger
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Smoking and mortality following acute myocardial infarction: Results from the national registry of myocardial infarction 2 (NRMI 2)
Nicotine and Tobacco Research, ISSN: 14622203
Steven G. Gourlay; Amy Chen Rundle; Hal V. Barron
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Predictors of door-to-balloon delay in primary angioplasty
American Journal of Cardiology, ISSN: 00029149
Brad G. Angeja; C.Michael Gibson; Richard Chin; Paul D. Frederick; Nathan R. Every; Ross; Gregg W Stone; Hal V. Barron
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ANGPTL3 stimulates endothelial cell adhesion and migration via integrin αvβ3 and induces blood vessel formation in vivo
Journal of Biological Chemistry, ISSN: 00219258
Camenisch; Pisabarro; Sherman; Joe Kowalski; Mark Nagel; Hass; Xie; Austin L. Gurney; Bodary; Xiao Huan Liang; Clark; Beresini; Napoleone Ferrara; Hans-Peter Gerber
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A novel type I cytokine receptor is expressed on monocytes, signals proliferation, and activates STAT-3 and STAT-5
Journal of Biological Chemistry, ISSN: 00219258
Nico Ghilardi; Ji Li; Hongo; Sothy Yi; Austin L. Gurney; Frederic J. De Sauvage
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Anti-adhesion antibodies Efalizumab, a humanized anti-CD11a monoclonal antibody
Transplant Immunology, ISSN: 09663274
Russell L Dedrick; Patricia Walicke; Marvin Garovoy
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Prostate stem cell antigen as therapy target: Tissue expression and in vivo efficacy of an immunoconjugate
Cancer Research, ISSN: 00085472
Ross; Spencer; Ilona N. Holcomb; Christine Tan; Hongo; Devaux; Linda Rangell; Gilbert-Andre Keller; Peter Schow; Rita M. Steeves; Robert J. Lutz; Gretchen D. Frantz; Kenneth J. Hillan; Franklin V. Peale Jr.; Tobin; Eberhard; Mark A. Rubin; Lasky; Koeppen
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Psoriasis as a model for T-cell-mediated disease: Immunobiologic and clinical effects of treatment with multiple doses of efalizumab, an anti-CD11a antibody
Archives of Dermatology, ISSN: 0003987X
Alice Gottlieb; James G. Krueger; Knut Wittkowski; Russell L Dedrick; Patricia Walicke; Marvin Garovoy
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Expression of full-length immunoglobulins in Escherichia coli: Rapid and efficient production of aglycosylated antibodies
Journal of Immunological Methods, ISSN: 00221759
Laura C. Simmons; Dorothea Reilly; Laura Klimowski; T. Shantha Raju; Meng; Paul Sims; Kyu Hong; Robert L. Shields; Lisa A. Damico; Rancatore; Yansura
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The forkhead transcription factor AFX activates apoptosis by induction of the BCL-6 transcriptional repressor
Journal of Biological Chemistry, ISSN: 00219258
Tracy Tzu-Ling Tang; Dowbenko; Amanda Jackson; Lisa Toney; Lewin; Alexander Dent; Lasky
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Increases in free, unbound insulin-like growth factor I enhance insulin responsiveness in human hepatoma G2 cells in culture
Journal of Biological Chemistry, ISSN: 00219258
Keiji Sakai; Henry B. Lowman; David R. Clemmons
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Synergistic induction of tumor antigens by Wnt-1 signaling and retinoic acid revealed by gene expression profiling
Journal of Biological Chemistry, ISSN: 00219258
David A. Tice; Szeto; Soloviev; Bonnee Rubinfeld; Fong; Dugger; Jane Winer; Mickey Williams; David Wieand; Victoria Smith; Ralph H. Schwall; Diane Pennica; Paul G. Polakis
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On the variability of covariate adjustment: Experience with Koch's method for evaluating the absolute difference in proportions in randomized clinical trials
Controlled Clinical Trials, ISSN: 01972456
Emmanuel Lesaffre; Kris Bogaerts; Xin Li; Bluhmki
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Fusion of two distinct peptide exosite inhibitors of Factor VIIa
Biochemical Journal, ISSN: 02646021
Roberge; Peek; Daniel Kirchhofer; Dennis; Lazarus
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The Erbin PDZ domain binds with high affinity and specificity to the carboxyl termini of δ-catenin and ARVCF
Journal of Biological Chemistry, ISSN: 00219258
Richard Laura; Andrea S. Witt; Heike A. Held; Gerstner; Deshayes; Michael F. T. Koehler; Kenneth S. Kosik; Sachdev S. Sidhu; Lasky
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Cardiotrophin-1 (CT-1) can protect the adult heart from injury when added both prior to ischaemia and at reperfusion
Cardiovascular Research, ISSN: 00086363
Zhihong Liao; Bhawanjit K. Brar; Qing Cai; Anastatis Stephanou; O'Leary; Diane Pennica; Derek M Yellon; David S. Latchman
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Lavage and nipple aspiration of breast ductal fluids: A source of biomarkers for environmental mutagenesis
Environmental and Molecular Mutagenesis, ISSN: 08936692
Pam Klein; Julia A. Lawrence
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Exaggerated hypotensive effect of vascular endothelial growth factor in spontaneously hypertensive rats
Hypertension, ISSN: 0194911X
Renhui Yang; Annie Ogasawara; Zioncheck; Zhen Ren; Guo-Wei He; Geralyn G. Deguzman; Nicolas Pelletier; Shen; Bunting; Hongkui Jin
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