Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 11501 - 11550 OF 15701 RESULTS

April 5, 2002

A dominant-negative p65 PAK peptide inhibits angiogenesis

Circulation Research, ISSN: 00097330

William B. Kiosses; John Hood; Suya Yang; Mary E. Gerritsen; David A. Cheresh; Nazilla Alderson; Martin Alexander Schwartz

April 5, 2002

SMAC negatively regulates the anti-apoptotic activity of melanoma inhibitor of apoptosis (ML-IAP)

Journal of Biological Chemistry, ISSN: 00219258

Domagoj Vucic; Deshayes; Heidi J. A. Wallweber; Pisabarro; Saloumeh Kadkhodayan; Wayne J. Fairbrother; Vishva M. Dixit

April 3, 2002

Biotransformation reactions of five-membered aromatic heterocyclic rings

Chemical Research in Toxicology, ISSN: 0893228X

Deepak Dalvie; Amit S. Kalgutkar; S. Cyrus Khojasteh; R. Scott Obach; John O'Donnell

April 1, 2002

Recombinant protein expression for therapeutic applications

Current Opinion in Biotechnology, ISSN: 09581669

Dana C. Andersen; Lynne Krummen

March 31, 2002

Progress in understanding the structure-activity relationships of P-glycoprotein

Advanced Drug Delivery Reviews, ISSN: 0169409X

Terry R Stouch; Gudmundsson

March 29, 2002

AKT/PKB phosphorylation of p21Cip/WAF1 enhances protein stability of p21Cip/WAF1 and promotes cell survival

Journal of Biological Chemistry, ISSN: 00219258

Ying Li; Dowbenko; Lasky

March 25, 2002

Inhibitors of protein-protein interactions

Expert Opinion on Therapeutic Patents, ISSN: 13543776

Denise A. Ockey; Thomas Gadek

March 25, 2002

A human antibody that inhibits factor IX/IXa function potently inhibits arterial thrombosis without increasing bleeding

Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN: 10795642

Refino; Surinc Er Jeet; Leo Deguzman; Bunting; Daniel Kirchhofer

March 15, 2002

Identification of a novel homotypic interaction motif required for the phosphorylation of receptor-interacting protein (RIP) by RIP3

Journal of Biological Chemistry, ISSN: 00219258

Xiaoqing Sun; Jianping Yin; Melissa A. Starovasnik; Wayne J. Fairbrother; Vishva M. Dixit

March 8, 2002

Characterization of endocrine gland-derived vascular endothelial growth factor signaling in adrenal cortex capillary endothelial cells

Journal of Biological Chemistry, ISSN: 00219258

Rui Lin; Jennifer Lecouter; Joe Kowalski; Napoleone Ferrara

March 7, 2002

Methylbenzene chemistry on zeolite HBeta: Multiple insights into methanol-to-olefin catalysis

Journal of Physical Chemistry B, ISSN: 10895647

Alain Sassi; Mark A. Wildman; Hee Jung Ahn; Paritosh Prasad; John B. Nicholas; James F. Haw

March 7, 2002

1H, 13C, and 15N resonance assignment of the vascular endothelial growth factor receptor-binding domain in complex with a receptor-blocking peptide [5]

Journal of Biomolecular NMR, ISSN: 09252738

Borlan Pan; Wayne J. Fairbrother

March 5, 2002

Expression profiling of a human cell line model of prostatic cancer reveals a direct involvement of interferon signaling in prostate tumor progression

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Shou; Robert Soriano; Simon W. Hayward; Gerald R. Cunha; P. Mickey Williams; Gao

March 5, 2002

Chemometric evaluation of on-line high-pressure liquid chromatography in mammalian cell cultures: Analysis of amino acids and glucose

Biotechnology and Bioengineering, ISSN: 00063592

Tina M. Larson; Martin Gawlitzek; Heather Evans; Urs Albers; Cacia

March 1, 2002

Microcirculation down under

Trends in Pharmacological Sciences, ISSN: 01656147

Tailoi Chan-Ling; Mary E. Gerritsen; Caryl E Hill; Paul Kubes; Michael Perry

March 1, 2002

Cardiac dysfunction in the trastuzumab clinical trials experience

Journal of Clinical Oncology, ISSN: 0732183X

Andrew Seidman; Clifford Hudis; Mary Kathryn Pierri; Steven Shak; Virginia Paton; Ashby; Maureen Murphy; Stanford J. Stewart; Deborah Keefe

February 22, 2002

Activation of the Wnt pathway interferes with serum response element-driven transcription of immediate early genes

Journal of Biological Chemistry, ISSN: 00219258

David A. Tice; Soloviev; Paul G. Polakis

February 15, 2002

Bacterial toxins as tools for mucosal vaccination

Drug Discovery Today, ISSN: 13596446

Mrsny; Daugherty; Marian McKee; David FitzGerald

February 15, 2002

Vascular endothelial-junctional adhesion molecule (VE-JAM)/JAM 2 interacts with T, NK, and dendritic cells through JAM 3

Journal of Immunology, ISSN: 00221767

Tony W. Liang; Chiu; Austin L. Gurney; Aiko Sidle; Daniel B. Tumas; Peter Schow; Foster; Toni Klassen; Kathryn Dennis; Richard A. Demarco; Thinh Q. Pham; Gretchen D. Frantz; Sherman Fong

February 15, 2002

The core membrane fusion complex governs the probability of synaptic vesicle fusion but not transmitter release kinetics

Journal of Neuroscience, ISSN: 02706474

Finley; Sejal M. Patel; Daniel V. Madison; Richard H. Scheller

February 15, 2002

Vascular endothelial-junctional adhesion molecule (VE-JAM)/JAM 2 interacts with T, NK, and dendritic cells through JAM 3

Journal of Immunology, ISSN: 00221767

Tony W. Liang; Chiu; Austin L. Gurney; Aiko Sidle; Daniel B. Tumas; Peter Schow; Foster; Toni Klassen; Kathryn Dennis; Richard A. Demarco; Thinh Q. Pham; Gretchen D. Frantz; Fong

February 11, 2002

Cold elicits the simultaneous induction of fatty acid synthesis and β-oxidation in murine brown adipose tissue: Prediction from differential gene expression and confirmation in vivo

FASEB Journal, ISSN: 08926638

Xing Xian; Lewin; William F. Forrest; Adams

February 8, 2002

Generation of an LFA-1 antagonist by the transfer of the ICAM-1 immunoregulatory epitope to a small molecule

Science, ISSN: 00368075

Thomas Gadek; Burdick; Robert S. McDowell; Mark S. Stanley; James C. Marsters Jr.; Kenneth J. Paris; David A. Oare; Mark E. Reynolds; Ladner; Kimberly Zioncheck; Wyne P. Lee; Gribling; Dennis; Nicholas J. Skelton; Daniel B. Tumas; Clark; Keating; Beresini; Tilley; Presta; Bodary

February 5, 2002

Nitrogen assimilation and growth of wheat under elevated carbon dioxide

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Arnold J. Bloom; David R. Smart; Duy T. Nguyen; Peter S. Searles

February 5, 2002

Surface-tension-confined microfluidics

Langmuir, ISSN: 07437463

Philippe Lam; Kenneth J. Wynne; Gary E. Wnek

February 5, 2002

Stable "zeta" peptides that act as potent antagonists of the high-affinity IgE receptor

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Nakamura; Mark E. Reynolds; Chen; Melissa A. Starovasnik; Henry B. Lowman

February 2, 2002

Host defense functions of proteolytically processed and parent (unprocessed) cathelicidins of rabbit granulocytes

Infection and Immunity, ISSN: 00199567

Kol A. Zarember; Seth S. Katz; Brian F. Tack; Laurence Doukhan; Weiss; Elsbach

January 25, 2002

PSTPIP is a substrate of PTP-PEST and serves as a scaffold guiding PTP-PEST toward a specific dephosphorylation of WASP

Journal of Biological Chemistry, ISSN: 00219258

Jean-François Côté; Ping Lin Chung; Jean-François Théberge; Maxime Hallé; Spencer; Lasky; Michel L. Tremblay

January 24, 2002

IL-17: Prototype member of an emerging cytokine family

Journal of Leukocyte Biology, ISSN: 07415400

Aggarwal; Austin L. Gurney

January 19, 2002

New insight into how tissue factor allosterically regulates Factor VIIa

Trends in Cardiovascular Medicine, ISSN: 10501738

Eigenbrot; Daniel Kirchhofer

January 15, 2002

Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines

Journal of Immunology, ISSN: 00221767

Kol A. Zarember; Godowski

January 8, 2002

Photodetachment and theoretical study of free and water-solvated nitrate anions, NO3-(H2O)n (n=0-6)

Journal of Chemical Physics, ISSN: 00219606

Xue-Bin Wang; Xin Yang; Lai-Sheng Wang; John B. Nicholas

January 1, 2002

MRI measurement of cerebral water diffusion and its application to experimental research

Biomedical Imaging in Experimental Neuroscience,

Richard A. D. Carano; Nicholas Van Bruggen; De Crespigny

January 1, 2002

Targeting ligand-activated ErbB2 signaling inhibits breast and prostate tumor growth

Cancer Cell, ISSN: 15356108

David B. Agus; Robert W. Akita; Fox; Gail D. Lewis; Higgins; Paul Pisacane; Julie A. Lofgren; Charles Tindell; Douglas P. Evans; Maiese; Scher; Mark X. Sliwkowski

January 1, 2002

Inconsistencies in reporting the occurrence and timing of first intercourse among adolescents

Journal of Sex Research, ISSN: 00224499

Dawn M. Upchurch; Lee A. Lillard; Carol S. Aneshensel; Nicole F. Li

January 1, 2002

Phase I study of the combination of losoxantrone and cyclophosphamide in patients with refractory solid tumours

British Journal of Cancer, ISSN: 00070920

Goh; Vokes; Amita Joshi; Ratain

January 1, 2002

Rituximab: Ongoing and future clinical development

Seminars in Oncology, ISSN: 00937754

Grillo-Lopez; Eric Hedrick; Michelle Rashford; Benyunes

January 1, 2002

Gene expression profiling in silico: Relative expression of candidate angiogenesis associated genes in renal cell carcinomas

Experimental Nephrology, ISSN: 10187782

Mary E. Gerritsen; Franklin V. Peale Jr.; Thomas D Wu

January 1, 2002

Rantes, a monocyte and T lymphocyte chemotactic cytokine releases histamine from human basophils

Journal of Immunology, ISSN: 00221767

Piotr Kuna; Sesha R. Reddigari; Thomas J. Schall; Doreen Rucinski; Michael Y. Viksman; Allen P. Kaplan

January 1, 2002

A membrane-permeant peptide that inhibits MLC kinase restores barrier function in in vitro models of intestinal disease

Gastroenterology, ISSN: 00165085

Yevgeny Zolotarevsky; Athanasia Koutsouris; Deborah E. Gonzalez; Quan; Jeffrey Tom; Mrsny; Jerrold R. Turner

January 1, 2002

Evaluation of total IGF-I assay methods using samples from Type I and Type II diabetic patients

Journal of Immunological Methods, ISSN: 00221759

Chestnut; Quarmby

January 1, 2002

Oncogenic human papillomavirus E6 proteins target the MAGI-2 and MAGI-3 proteins for degradation

Oncogene, ISSN: 09509232

Miranda Thomas; Richard Laura; Karin Hepner; Ernesto Guccione; Charles L. Sawyers; Lasky; Lawrence Banks

January 1, 2002

Targeting ligand-activated ErbB2 signaling inhibits breast and prostate tumor growth

Cancer Cell, ISSN: 15356108

Agus; Robert W. Akita; Fox; Gail D. Lewis; Higgins; Paul Pisacane; Julie A. Lofgren; Charles Tindell; Douglas P. Evans; Maiese; Scher; Mark X. Sliwkowski

January 1, 2002

In silico data filtering to identify new angiogenesis targets from a large in vitro gene profiling data set

Physiological Genomics, ISSN: 15312267

Mary E. Gerritsen; Robert Soriano; Suya Yang; Gladys S. Ingle; Constance Zlot; Toy; Jane Winer; Aparna Draksharapu; Franklin V. Peale Jr.; Thomas D Wu; P. Mickey Williams

January 1, 2002

Tumor-cell resistance to death receptor-induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax

Nature Medicine, ISSN: 10788956

Heidi LeBlanc; David Lawrence; Eugene Varfolomeev; Klara Totpal; John Morlan; Peter Schow; Fong; Ralph H. Schwall; Sinicropi; Avi Ashkenazi

January 1, 2002

Safety and efficacy of alteplase for restoring function in occluded central venous catheters: Results of the cardiovascular thrombolytic to open occluded lines trial

Journal of Clinical Oncology, ISSN: 0732183X

Steven R. Deitcher; Mark R Fesen; Paul M Kiproff; Hill; Xin Li; Edward R. McCluskey; Charles P. Semba

January 1, 2002

EG-VEGF and the concept of tissue-specific angiogenic growth factors

Seminars in Cell and Developmental Biology, ISSN: 10849521

Jennifer Lecouter; Napoleone Ferrara

January 1, 2002

Production information management

Pharmaceutical Technology, ISSN: 01478087

Hans Koning-Bastiaan

January 1, 2002

Validation of large-scale chromatographic processes, Part 1: Case study of neuleze capture on Macroprep High-S

BioPharm, ISSN: 10408304

Timothy N. Breece; Ellen Gilkerson; Charles H. Schmelzer

January 1, 2002

Enhancing the anticoagulant potency of soluble tissue factor mutants by increasing their affinity to factor VIIa

Thrombosis and Haemostasis, ISSN: 03406245

Yang; Geoffrey F. Lee; Markus A. Riederer; Robert F. Kelley

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