Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 11651 - 11700 OF 15583 RESULTS

January 1, 2001

Tissue microarray (TMA) technology: Miniaturized pathology archives for high-throughput in situ studies

Journal of Pathology, ISSN: 00223417

Franklin V. Peale Jr.; Mary E. Gerritsen

January 1, 2001

Mutations altering leaf morphology in tomato

International Journal of Plant Sciences, ISSN: 10585893

Sharon Kessler; Minsung Kim; Thinh Q. Pham; Natalie Weber; Neelima Sinha

January 1, 2001

Regulation of the association between PSTPIP and CD2 in murine T cells

Experimental and Molecular Pathology, ISSN: 00144800

Yalai Bai; Yaozhong Ding; Yalai Bai; Yaozhong Ding; Jonathan S. Bromberg; Spencer; Lasky

January 1, 2001

First-line, single-agent Herceptin® (trastuzumab) in metastatic breast cancer: A preliminary report

European Journal of Cancer, ISSN: 09598049

Charles L. Vogel; Melody A. Cobleigh; Debasish Tripathy; John C. Gutheil; Lyndsay N. Harris; Louis Fehrenbacher; Dennis J. Slamon; Maureen Murphy; Novotny; Michael Burchmore; Shak; Stanford J. Stewart

January 1, 2001

Hepatocyte growth factor enhances vascular endothelial growth factor-induced angiogenesis in vitro and in vivo

American Journal of Pathology, ISSN: 00029440

Xiaohua Xin; Suya Yang; Gladys S. Ingle; Constance Zlot; Linda Rangell; Joe Kowalski; Ralph H. Schwall; Napoleone Ferrara; Mary E. Gerritsen

January 1, 2001

A specific molar ratio of stabilizer to protein is required for storage stability of a lyophilized monoclonal antibody

Journal of Pharmaceutical Sciences, ISSN: 00223549

Cleland; Lam; Brent Kendrick; Yang; Tzung-Horng Yang; David E. Overcashier; Brooks; Chung C. Hsu; John F. Carpenter

January 1, 2001

Distribution and localization of CMP-N-acetylneuraminic acid hydroxylase and N-glycolylneuraminic acid-containing glycoconjugates in porcine lymph node and peripheral blood lymphocytes

European Journal of Cell Biology, ISSN: 01719335

Yanina N. Malykh; Brigitte Krisch; Lee Shaw; Warner; Sinicropi; Roanne Smith; Joseph Chang; Roland Schauer

January 1, 2001

Validating the sanitization of chromatographic resins: A sample case study

BioPharm, ISSN: 10408304

Hiraoka-Sutow; Broughton

January 1, 2001

The external granule layer of the developing chick cerebellum generates granule cells and cells of the isthmus and rostral hindbrain

Journal of Neuroscience, ISSN: 02706474

John C. Lin; Li Cai; Constance L. Cepko

January 1, 2001

An improved method for the extraction of SV40 DNA for real-time quantitative PCR assay

American Biotechnology Laboratory, ISSN: 07493223

Shi; Yuan Xu

January 1, 2001

Migrating, archiving, and reconstructing electronic records in a regulatory environment

Drug Information Journal, ISSN: 00928615

Woodrum

January 1, 2001

Capillary Electrophoresis as a Routine Analytical Tool in Pharmaceutical Analysis

LC-GC Europe, ISSN: 14716577

Kevin D. Altria; Chen; Lilian Clohs

January 1, 2001

Downregulation of Hedgehog signaling is required for organogenesis of the small intestine in Xenopus

Developmental Biology, ISSN: 00121606

Jian Zhang; Rosenthal; Frederic J. De Sauvage; Ramesh A. Shivdasani

January 1, 2001

Metal-catalyzed oxidation of human growth hormone: Modulation by solvent-induced changes of protein conformation

Journal of Pharmaceutical Sciences, ISSN: 00223549

Susan W. Hovorka; Jinyang Hong; Cleland; Christian Schöneich

January 1, 2001

Determination of a weight-adjusted dose of TNK-tissue plasminogen activator

American Heart Journal, ISSN: 00028703

Wang-Clow; Fox; Christopher P. Cannon; C.Michael Gibson; Berioli; Bluhmki; Danays; Eugene Braunwald; Frans Van De Werf; David Stump

January 1, 2001

Characterization of EDTA-soluble polysaccharides from the scape of Musa paradisiaca (banana)

Biotechnology and Applied Biochemistry, ISSN: 08854513

T. Shantha Raju; Jagadish; Anjaneyalu

January 1, 2001

Binding protein-3-selective insulin-like growth factor I variants: Engineering, biodistributions, and clearance

Endocrinology, ISSN: 00137227

Yves Dubaquié; Deborah L. Mortensen; Anthony Intintoli; Deborah A. Hogue; Nakamura; Rancatore; Philip M. Lester; Michael D Sadick; Ellen H. Filvaroff; Fielder; Henry B. Lowman

January 1, 2001

Heparin coinfusion during convection-enhanced delivery (CED) increases the distribution of the glial-derived neurotrophic factor (GDNF) ligand family in rat striatum and enhances the pharmacological activity of neurturin

Experimental Neurology, ISSN: 00144886

John F. Hamilton; Paul F. Morrison; Michael Y. Chen; Judith Harvey-White; Rosario S. Pernaute; Phillips; Edward Oldfield; Krys S. Bankiewicz

January 1, 2001

Effect of NGF and neurotrophin-3 treatment on experimental diabetic autonomic neuropathy

Journal of Neuropathology and Experimental Neurology, ISSN: 00223069

Robert E. Schmidt; Denise A. Dorsey; Lucie N. Beaudet; Curtis A. Parvin; Escandon

January 1, 2001

Power consumption profiles in high-shear wet granulation. II: Predicting the overwetting point from a spreading energy

Journal of Pharmaceutical Sciences, ISSN: 00223549

Cleland; Lam; Brent Kendrick; Yang; Tzung-Horng Yang; David E. Overcashier; Brooks; Chung C. Hsu; John F. Carpenter

January 1, 2001

Assays for human DNase I activity in biological matrices.

Methods in Molecular Biology, ISSN: 10643745

Sinicropi; Lazarus

January 1, 2001

Engineered properties and assays for human DNase I mutants.

Methods in Molecular Biology, ISSN: 10643745

Clark Q. Pan; Sinicropi; Lazarus

January 1, 2001

Selective expression of murine prostate stem cell antigen in fetal and adult tissues and the transgenic adenocarcinoma of the mouse prostate model of prostate carcinogenesis

American Journal of Pathology, ISSN: 00029440

Ross; Spencer; Lasky; Koeppen

January 1, 2001

Leptospiral lipopolysaccharide activates cells through a TLR2-dependent mechanism

Nature Immunology, ISSN: 15292908

Catherine Werts; Richard I. Tapping; John C. Mathison; Tsung-Hsien Chuang; Vladimir Kravchenko; Saint-Girons; David A. Haake; Godowski; Fumitaka Hayashi; Adrian Ozinsky; David M. Underhill; Carsten J. Kirschning; Hermann Wagner; Alan Aderem; Peter S. Tobias; Richard J. Ulevitch

January 1, 2001

Generation of a humanized, high affinity anti-tissue factor antibody for use as a novel antithrombotic therapeutic

Thrombosis and Haemostasis, ISSN: 03406245

Presta; Paul Sims; Meng; Paul Moran; Sherron L. Bullens; Bunting; Schoenfeld; David G Lowe; Lai; Rancatore; Iverson; Lim; Chisholm; Robert F. Kelley; Markus A. Riederer; Daniel Kirchhofer

January 1, 2001

Terms of reference for Data and Safety Monitoring Committees

American Heart Journal, ISSN: 00028703

Milton Packer; Janet Wittes; David Stump

January 1, 2001

Vitamin a intake affects the contribution of chylomicrons vs. Retinol-binding protein to milk vitamin A in lactating rats

Journal of Nutrition, ISSN: 00223166

Michael H. Green; Joanne Balmer Green; Sylvie A. Akohoue; Sean K. Kelley

January 1, 2001

CD62L is required on effector cells for local interactions in the CNS to cause myelin damage in experimental allergic encephalomyelitis

Immunity, ISSN: 10747613

Iqbal S. Grewal; Harald G. Foellmer; Kate D. Grewal; Hua Wang; Wyne P. Lee; Daniel B. Tumas; Charles A. Janeway Jr.; Richard A. Flavell

January 1, 2001

Induction of gp91-phox, a component of the phagocyte NADPH oxidase, in microglial cells during central nervous system inflammation

Journal of Cerebral Blood Flow and Metabolism, ISSN: 0271678X

Green; Cairns; Julie Rae; Errett-Baroncini; Hongo; Erickson; John T. Curnutte

January 1, 2001

Concordance for Type 1 Diabetes in Identical Twins Is Affected by Insulin Genotype

Diabetes Care, ISSN: 01495992

Karl A. Metcalfe; Graham A. Hitman; Rachel E. Rowe; Mohammed Hawa; Huang; Stewart; R. David G. Leslie

January 1, 2001

Matrix-assisted laser desorption/ionization time-of-flight mass analysis of peptides.

Current protocols in protein science / editorial board, John E. Coligan ... [et al.], ISSN: 19343663

William J. Henzel; Stults

January 1, 2001

Acute coronary syndromes

Annals of Emergency Medicine, ISSN: 01960644

Thomas Aufderheide; Leo L. Bossaert; John Field; Johan Herlitz; Alain Leizorovicz; Katherine A. Littrell; Joseph P. Ornato; Mary Ann Peberdy; Flavio Ribichini

January 1, 2001

Growth of children in two economically diverse Peruvian high-altitude communities

American Journal of Human Biology, ISSN: 10420533

Pawson; Huicho; Muro; Pacheco

January 1, 2001

Effects of in vivo heregulin β1 treatment in wild-type and ErbB gene-targeted mice depend on receptor levels and pregnancy

American Journal of Pathology, ISSN: 00029440

Sue O'Shea; Kent J. Johnson; Ross Clark; Mark X. Sliwkowski; Sharon Erickson

January 1, 2001

Cardiology Clinics: Preface

Cardiology Clinics, ISSN: 07338651

Jagat Narula; Vishva M. Dixit; Leslie W. Miller

January 1, 2001

The use of intra-aortic balloon counterpulsation in patients with cardiogenic shock complicating acute myocardial infarction: Data from the national registry of myocardial infarction 2

American Heart Journal, ISSN: 00028703

Hal V. Barron; Nathan R. Every; Lori Parsons; Brad G. Angeja; Robert J. Goldberg; Joel M. Gore; Tony M. Chou

January 1, 2001

Activation of expression of hedgehog target genes in basal cell carcinomas

Journal of Investigative Dermatology, ISSN: 0022202X

Jeannette M. Bonifas; Sally Pennypacker; Pao-Tien Chuang; Andrew P. McMahon; Mickey P. Williams; Rosenthal; Frederic J. De Sauvage; Ervin H. Epstein Jr.

January 1, 2001

Anti-IgE efficacy in murine asthma models is dependent on the method of allergen sensitization

Journal of Allergy and Clinical Immunology, ISSN: 00916749

Daniel B. Tumas; Betty Chan; Winifred R. Werther; Wrin; Vennari; Noelyn Desjardin; Robert L. Shields; Paula Jardieu

January 1, 2001

Nerve growth factor: Structure and function

Cellular and Molecular Life Sciences, ISSN: 1420682X

Wiesmann; De Vos

January 1, 2001

Role of vascular endothelial growth factor in regulation of physiological angiogenesis

American Journal of Physiology - Cell Physiology, ISSN: 03636143

Napoleone Ferrara

January 1, 2001

Genetic variation in physiological sensitivity to estrogen in mice

APMIS, ISSN: 09034641

Jimmy L. Spearow; Peter O'Henley; Paul Doemeny; Robyn Sera; Rachael Leffler; Taki Sofos; Marylynn Barkley

January 1, 2001

Alteplase and tenecteplase: Applications in the peripheral circulation

Techniques in Vascular and Interventional Radiology, ISSN: 10892516

Charles P. Semba; Koji Sugimoto; Mahmood K Razavi

January 1, 2001

Angiogenesis and chronic disease

Trends in Molecular Medicine, ISSN: 14714914

Mary E. Gerritsen

January 1, 2001

Recombinant tissue plasminogen activator (alteplase) for restoration of flow in occluded central venous access devices: A double-blind placebo-controlled trial - The cardiovascular thrombolytic to open occluded lines (COOL) efficacy trial

Journal of Vascular and Interventional Radiology, ISSN: 10510443

Ponec; David Irwin; Haire; Hill; Xin Li; Edward R. McCluskey

January 1, 2001

Engineering M13 for phage display

Biomolecular Engineering, ISSN: 13890344

Sachdev S. Sidhu

January 1, 2001

Industrial purification of pharmaceutical antibodies: Development, operation, and validation of chromatography processes

Biotechnology and Genetic Engineering Reviews, ISSN: 02648725

Fahrner; Knudsen; Basey; Walter Galan; Feuerhelm; Vanderlaan; Gregory S. Blank

January 1, 2001

Use of reperfusion therapies in elderly patients with acute myocardial infarction

Drugs and Aging, ISSN: 1170229X

Brad G. Angeja; C.Michael Gibson; Richard Chin; John G. Canto; Hal V. Barron

January 1, 2001

Combinatorial chemistry in steroid receptor drug discovery.

Methods in Molecular Biology, ISSN: 10643745

Flygare; Daniel P. Sutherlin; Brown

January 1, 2001

Effect of moisture on the stability of a lyophilized humanized monoclonal antibody formulation

Pharmaceutical Research, ISSN: 07248741

Breen; Curley; David E. Overcashier; Chung C. Hsu; Steven J. Shire

January 1, 2001

Encapsulation and stabilization of nerve growth factor into poly(lactic-co-glycolic) acid microspheres

Journal of Pharmaceutical Sciences, ISSN: 00223549

Lam; Duenas; Cleland

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