Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 11751 - 11800 OF 15583 RESULTS

November 1, 2000

Effects of VEGF on hemodynamics and cardiac function: Characterization and mechanisms

IDrugs, ISSN: 13697056

Renhui Yang; Bunting; Hongkui Jin

November 1, 2000

Cleavage and identification of proteins: A modified aspartyl-prolyl cleavage

Analytical Chemistry, ISSN: 00032700

Kishiyama; Zemin Zhang; William J. Henzel

October 30, 2000

Gli regulation by the opposing activities of fused and suppressor of fused

Nature Cell Biology, ISSN: 14657392

Maximilien Murone; Shiuh-Ming Luoh; Donna Stone; Wenlu Li; Austin L. Gurney; Armanini; Christa Grey; Rosenthal; Frederic J. De Sauvage

October 19, 2000

Development of Th1-type immune responses requires the type I cytokine receptor TCCR

Nature, ISSN: 00280836

Qi Chen; Nico Ghilardi; Hua Wang; Thad Baker; Xie; Austin L. Gurney; Iqbal S. Grewal; Frederic J. De Sauvage

October 15, 2000

Inhibition of HER2/neu (erbB-2) and mitogen-activated protein kinases enhances tamoxifen action against HER2-overexpressing, tamoxifen-resistant breast cancer cells

Cancer Research, ISSN: 00085472

Hirokazu Kurokawa; Anne E. G. Lenferink; Jean F. Simpson; Paul Pisacane; Mark X. Sliwkowski; James T. Forbes; Carlos L. Arteaga

October 6, 2000

Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R

Journal of Biological Chemistry, ISSN: 00219258

Xie; Aggarwal; Ho; Foster; Zhang; Stinson; William I. Wood; Goddard; Austin L. Gurney

October 5, 2000

Multiple cell culture factors can affect the glycosylation of Asn-184 in CHO-produced tissue-type plasminogen activator

Biotechnology and Bioengineering, ISSN: 00063592

Dana C. Andersen; Tiffany Bridges; Martin Gawlitzek; Cynthia Hoy

October 1, 2000

Achieving neuronal patterning by repression

Nature Neuroscience, ISSN: 10976256

Donna Stone; Rosenthal

September 29, 2000

ICEBERG: A novel inhibitor of interleukin-1β generation

Cell, ISSN: 00928674

Eric W. Humke; Stephanie K. Shriver; Melissa A. Starovasnik; Wayne J. Fairbrother; Vishva M. Dixit

September 28, 2000

Tethering of CpxP to the inner membrane prevents spheroplast induction of the Cpx envelope stress response

Molecular Microbiology, ISSN: 0950382X

Tracy L. Raivio; Mike Laird; John C. Joly; Thomas J. Silhavy

September 27, 2000

The G-protein inhibitor, pertussis toxin, inhibits the secretion of brain-derived neurotrophic factor

Neuroscience, ISSN: 03064522

Gunther; Von Bartheld; Goodman; Johnson; Bothwell

September 22, 2000

Receptor-selective variants of human vascular endothelial growth factor. Generation and characterization

Journal of Biological Chemistry, ISSN: 00219258

Bing Li; Fuh; Meng; Xiaohua Xin; Mary E. Gerritsen; Cunningham; De Vos

September 22, 2000

The coiled-coil domain of occludin can act to organize structural and functional elements of the epithelial tight junction

Journal of Biological Chemistry, ISSN: 00219258

Asma Nusrat; Jason A. Chen; Chris S. Foley; Tony W. Liang; Jeffrey Tom; Cromwell; Quan; Mrsny

September 15, 2000

MDM2 interacts with the C-terminus of the catalytic subunit of DNA polymerase ε

Nucleic Acids Research, ISSN: 03051048

Nikolina Vlatkovic; Stephanie Guerrera; Ying Li; Stuart Linn; Dale S. Haines; Mark T. Boyd

September 15, 2000

Deficiency of T2K leads to apoptotic liver degeneration and impaired NF-κB-dependent gene transcription

EMBO Journal, ISSN: 02614189

Madeleine Bonnard; Christine Mirtsos; Shinobu Suzuki; Kevin Graham; Jianing Huang; Michelle Ng; Annick Itié; Andrew Wakeham; Arda Shahinian; William J. Henzel; Andrew J. Elia; Wendy Shillinglaw; Tak W. Mak; Zhaodan Cao; Wen-Chen Yeh

September 4, 2000

Statistical analysis of the long-term effects of recombinant human deoxyribonuclease on pulmonary function in cystic fibrosis patients

Journal of Biopharmaceutical Statistics, ISSN: 10543406

John J. Chen; Scott A. Hamilton

September 4, 2000

Statistical analysis of the long-term effects of recombinant human deoxyribonuclease on pulmonary function in cystic fibrosis patients

Journal of Biopharmaceutical Statistics, ISSN: 10543406

John J. Chen; Scott Hamilton

September 2, 2000

Wnt signaling and cancer

Genes and Development, ISSN: 08909369

Paul G. Polakis

September 1, 2000

Ternary complex between placental lactogen and the extracellular domain of the prolactin receptor

Nature Structural Biology, ISSN: 10728368

Patricia A. Elkins; Hans W. Christinger; Yael Sandowski; Edna Sakal; Arieh Gertler; De Vos; Anthony A. Kossiakoff

September 1, 2000

Efficient phage display of polypeptides fused to the carboxy-terminus of the M13 gene-3 minor coat protein

FEBS Letters, ISSN: 00145793

Fuh; Sachdev S. Sidhu

September 1, 2000

The interaction of neuropilin-1 in vascular endothelial growth factor and its receptor Flt-1

Journal of Biological Chemistry, ISSN: 00219258

Fuh; Garcia; De Vos

September 1, 2000

A comparison of different methods to determine the end of exponential growth in CHO cell cultures for optimization of scale-up

Biotechnology Progress, ISSN: 87567938

Schoenherr; Stapp; Thomas Ryll

August 26, 2000

Antibody binding regions on human nerve growth factor identified by homolog- and alanine-scanning mutagenesis

Hybridoma, ISSN: 0272457X

Hongo; Laramee; Urfer; David L. Shelton; Restivo; Michael D Sadick; Galloway; Chu; Winslow

August 25, 2000

Smoothened activates Gα(i)-mediated signaling in frog melanophores

Journal of Biological Chemistry, ISSN: 00219258

Dianne L. DeCamp; Teresa M. Thompson; Frederic J. De Sauvage; Michael R. Lerner

August 20, 2000

Performance of small-scale CHO perfusion cultures using an acoustic cell filtration device for cell retention: Characterization of separation efficiency and impact of perfusion on product quality

Biotechnology and Bioengineering, ISSN: 00063592

Thomas Ryll; George Dutina; Arthur Reyes; Jane Gunson; Lynne Krummen; Etcheverry

August 18, 2000

Enzyme mechanisms for polycyclic triterpene formation

Angewandte Chemie - International Edition, ISSN: 14337851

K. Ulrich Wendt; Georg E. Schulz; Elias J. Corey; David R. Liu

August 18, 2000

Vitronectin receptor antagonists: Purine-based peptidomimetics

Angewandte Chemie - International Edition, ISSN: 14337851

Peyman; Gourvest; Thomas Gadek; Knolle

August 15, 2000

VEGF regulates cell behavior during vasculogenesis

Developmental Biology, ISSN: 00121606

Christopher J. Drake; Amanda LaRue; Napoleone Ferrara; Charles D. Little

August 11, 2000

The 3' UTR of human MnSOD mRNA hybridizes to a small cytoplasmic RNA and inhibits gene expression

Biochemical and Biophysical Research Communications, ISSN: 0006291X

Joseph J. Stuart; Levente A. Egry; Grace H.W. Wong; Roger L. Kaspar

August 2, 2000

Genetic studies in idiopathic short stature

Current Opinion in Pediatrics, ISSN: 10408703

Kenneth M. Attie

August 1, 2000

Analysis of glycoconjugates: II. Electrophoresis

Analytical Biochemistry, ISSN: 00032697

T. Shantha Raju

August 1, 2000

A repressor sequence in the juxtamembrane domain of Flt-1 (VEGFR-1) constitutively inhibits vascular endothelial growth factor-dependent phosphatidylinositol 3'-kinase activation and endothelial cell migration

EMBO Journal, ISSN: 02614189

Hendrik Gille; Joe Kowalski; Lanlan Yu; Helen Chen; Pisabarro; Terri Davis-Smyth; Napoleone Ferrara

August 1, 2000

FIZZ1, a novel cysteine-rich secreted protein associated with pulmonary inflammation, defines a new gene family

EMBO Journal, ISSN: 02614189

Ilona N. Holcomb; Rhona C. Kabakoff; Betty Chan; Thad Baker; Austin L. Gurney; William J. Henzel; Nelson; Henry B. Lowman; Wright; Nicholas J. Skelton; Gretchen D. Frantz; Daniel B. Tumas; Franklin V. Peale Jr.; David L. Shelton; Hébert

August 1, 2000

Electrophoretic methods for the analysis of N-linked oligosaccharides

Analytical Biochemistry, ISSN: 00032697

T. Shantha Raju

August 1, 2000

Rapid mapping of protein functional epitopes by combinatorial alanine scanning

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Gregory A. Weiss; Colin K. Watanabe; Zhong; Goddard; Sachdev S. Sidhu

July 28, 2000

Identification and cloning of two histone fold motif-containing subunits of HeLa DNA polymerase ε

Journal of Biological Chemistry, ISSN: 00219258

Ying Li; Zachary F. Pursell; Stuart Linn

July 27, 2000

Fringe is a glycosyltransferase that modifies Notch

Nature, ISSN: 00280836

Daniel J. Moloney; Vladislav M. Panin; Stuart H. Johnston; Jihua Chen; Li Shao; Richa Wilson; Yang Wang; Pamela Stanley; Kenneth D. Irvine; Robert S. Haltiwanger; Thomas F. Vogt

July 15, 2000

Increased binding activity at an antioxidant-responsive element in the metallothionein-1 promoter and rapid induction of metallothionein-1 and -2 in response to cerebral ischemia and reperfusion

Journal of Neuroscience, ISSN: 02706474

Menno Van Lookeren Campagne; Harold Thibodeaux; Nicholas Van Bruggen; Cairns; David G Lowe

July 14, 2000

Interaction of the tumor suppressor PTEN/MMAC with a PDZ domain of MAGI3, a novel membrane-associated guanylate kinase

Journal of Biological Chemistry, ISSN: 00219258

Yan Wu; Dowbenko; Spencer; Richard Laura; James Lee; Qimin Gu; Lasky

July 14, 2000

Analysis of PDZ domain-ligand interactions using carboxyl-terminal phage display

Journal of Biological Chemistry, ISSN: 00219258

Fuh; Pisabarro; Ying Li; Quan; Lasky; Sachdev S. Sidhu

July 5, 2000

Purification of plasmid DNA by tangential flow filtration

Biotechnology and Bioengineering, ISSN: 00063592

David W. Kahn; Michelle D. Butler; Darien L. Cohen; Margaret Gordon; Jeanne Kahn; Winkler

July 3, 2000

The apoptotic signaling pathway activated by Toll-like receptor-2

EMBO Journal, ISSN: 02614189

Antonios O. Aliprantis; Ruey-Bing Yang; David S. Weiss; Godowski; Arturo Zychlinsky

July 3, 2000

Sustained release of recombinant human insulin-like growth factor-I for treatment of diabetes

Journal of Controlled Release, ISSN: 01683659

Lam; Duenas; Daugherty; Nancy Levin; Cleland

July 1, 2000

Broad specificity of GDNF family receptors GFRα1 and GFRα2 for GDNF and NTN in neurons and transfected cells

Journal of Neuroscience Research, ISSN: 03604012

Li-Chong Wang; Shih; Hongo; Devaux; Mary Hynes

June 30, 2000

Modulation of tight junction function by G protein-coupled events

Advanced Drug Delivery Reviews, ISSN: 0169409X

Ann M. Hopkins; Dinxi Li; Mrsny; Shaun V. Walsh; Asma Nusrat

June 30, 2000

Design evolution of artificial M13 coat proteins

Journal of Molecular Biology, ISSN: 00222836

Gregory A. Weiss; Sachdev S. Sidhu

June 28, 2000

Prevalence, clinical characteristics, and mortality among patients with myocardial infarction presenting without chest pain

JAMA - Journal of the American Medical Association, ISSN: 00987484

John G. Canto; Michael G. Shlipak; William J. Rogers; Judith A. Malmgren; Paul D. Frederick; Costas Lambrew; Joseph P. Ornato; Hal V. Barron; Calarina I. Kiefe

June 28, 2000

Development and qualification of a novel virus removal filter for cell culture applications

Biotechnology Progress, ISSN: 87567938

Shengjiang Liu; Mark Carroll; Raquel Iverson; Christine Valera; Vennari; Kimberly Turco; Robert Piper; Robert Kiss; Herbert Lutz

June 27, 2000

The tissue factor region that interacts with substrates factor IX and factor X

Biochemistry, ISSN: 00062960

Daniel Kirchhofer; Michael T. Lipari; Paul Moran; Eigenbrot; Robert F. Kelley

June 20, 2000

Ammonium alters N-glycan structures of recombinant TNFR-IgG: Degradative versus biosynthetic mechanisms

Biotechnology and Bioengineering, ISSN: 00063592

Martin Gawlitzek; Thomas Ryll; James A. Lofgren; Mary B. Sliwkowski

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