Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 11751 - 11800 OF 15701 RESULTS

Vascular Endothelial Growth Factor KDR Receptor Signaling Potentiates Tumor Necrosis Factor-induced Tissue Factor Expression in Endothelial Cells
Journal of Biological Chemistry, ISSN: 00219258
Shen; David Y. Lee; Karen M. Cortopassi; Lisa A. Damico; Zioncheck
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Cardiotrophin-1, a muscle-derived cytokine, is required for the survival of subpopulations of developing motoneurons
Journal of Neuroscience, ISSN: 02706474
Ronald W. Oppenheim; Stefan Wiese; David Prevette; Armanini; Siwei Wang; Lucien J. Houenou; Bettina Holtmann; Rudolf Götz; Diane Pennica; Michael Sendtner
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Elimination pathways of [14C]losoxantrone in four cancer patients
Drug Metabolism and Disposition, ISSN: 00909556
Amita Joshi; Pieniaszek H.J.; Vokes; Nicholas J. Vogelzang; Davidson; Richards; Chai; Finizio; Ratain
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Vascular endothelial growth factor-mediated endothelium- dependent relaxation is blunted in spontaneously hypertensive rats
Journal of Pharmacology and Experimental Therapeutics, ISSN: 00223565
Ming-Hui Liu; Hongkui Jin; H. Storm Floten; Qin Yang; Anthony P. C. Yim; Anthony Furnary; Zioncheck; Bunting; Guo-Wei He
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Effects of early angiotensin-converting enzyme inhibition on cardiac gene expression after acute myocardial infarction
Circulation, ISSN: 00097322
Hongkui Jin; Renhui Yang; Tarif A. Awad; Fay Wang; Wei Li; Simon P. Williams; Annie Ogasawara; Brian Shimada; P. Mickey Williams; Gianfranco De Feo; Nicholas F. Paoni
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Analysis of biological effects and signaling properties of Flt-1 (VEGFR-1) and KDR (VEGFR-2): A reassessment using novel receptor-specific vascular endothelial growth factor mutants
Journal of Biological Chemistry, ISSN: 00219258
Hendrik Gille; Joe Kowalski; Bing Li; Jennifer Lecouter; Moffat; Zioncheck; Nicolas Pelletier; Napoleone Ferrara
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Untangling the ErbB signalling network
Nature Reviews Molecular Cell Biology, ISSN: 14710072
Yarden; Mark X. Sliwkowski
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Bispecific human IgG by design
Journal of Immunological Methods, ISSN: 00221759
Paul J. Carter
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A minimal peptide scaffold for β-turn display: Optimizing a strand position in disulfide-cyclized β-hairpins
Journal of the American Chemical Society, ISSN: 00027863
Andrea G Cochran; Tong; Melissa A. Starovasnik; Park; Robert S. McDowell; Theaker; Nicholas J. Skelton
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The tissue factor region that interacts with factor Xa in the activation of factor VII
Biochemistry, ISSN: 00062960
Daniel Kirchhofer; Eigenbrot; Michael T. Lipari; Paul Moran; Peek; Robert F. Kelley
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Engraftment of autologous retrovirally transduced hepatocytes after intraportal transplantation into nonhuman primates: Implication for ex vivo gene therapy
Human Gene Therapy, ISSN: 10430342
Andreoletti; Nathalie Loux; Corinne Vons; Tuan Huy Nguyen; Lorand; Mahieu; Simon; Di Rico; Vingert; Chapman; Pascale Briand; Ralph H. Schwall; Hamza; Capron; Bargy; Dominique Franco; Anne Weber
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Overexpression of the human 2-oxoglutarate carrier lowers mitochondrial membrane potential in HEK-293 cells: Contrast with the unique cold-induced mitochondrial carrier CGI-69
Biochemical Journal, ISSN: 02646021
Yu; Lewin; Zhong; Brush; Peter Schow; Steve Sherwood; Pan; Adams
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IL-17E, a novel proinflammatory ligand for the IL-17 receptor homolog IL-17Rh1
Journal of Biological Chemistry, ISSN: 00219258
James Lee; Ho; Maruoka; Corpuz; Daryl T. Baldwin; Foster; Goddard; Yansura; Richard L. Vandlen; William I. Wood; Austin L. Gurney
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The RelA(p65) subunit of NF-κB is essential for inhibiting double-stranded RNA-incluced cytotoxicity
Journal of Biological Chemistry, ISSN: 00219258
Ming Li; Wendy Shillinglaw; William J. Henzel; Amer A. Beg
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Membrane ion-exchange chromatography for process-scale antibody purification
Journal of Chromatography A, ISSN: 00219673
Knudsen; Fahrner; Yuan Xu; Lenore A Norling; Gregory S. Blank
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IL-1H, an interleukin 1-related protein that binds IL-18 receptor/IL-1Rrp
Cytokine, ISSN: 10434666
Pan; Risser; Mao; Daryl T. Baldwin; Zhong; Ellen H. Filvaroff; Yansura; Lhney Lewis; Eigenbrot; William J. Henzel; Richard L. Vandlen
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Similarity of the Escherichia coli proteome upon completion of different biopharmaceutical fermentation processes
Proteomics, ISSN: 16159853
Kathleen M. Champion; Julie C. Nishihara; John C. Joly; David Arnott
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A specific molar ratio of stabilizer to protein is required for storage stability of a lyophilized monoclonal antibody
Journal of Pharmaceutical Sciences, ISSN: 00223549
Cleland; Lam; Brent Kendrick; Yang; Tzung-Horng Yang; David E. Overcashier; Brooks; Chung C. Hsu; John F. Carpenter
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Tissue microarray (TMA) technology: Miniaturized pathology archives for high-throughput in situ studies
Journal of Pathology, ISSN: 00223417
Franklin V. Peale Jr.; Mary E. Gerritsen
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Mutations altering leaf morphology in tomato
International Journal of Plant Sciences, ISSN: 10585893
Sharon Kessler; Minsung Kim; Thinh Q. Pham; Natalie Weber; Neelima Sinha
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Regulation of the association between PSTPIP and CD2 in murine T cells
Experimental and Molecular Pathology, ISSN: 00144800
Yalai Bai; Yaozhong Ding; Yalai Bai; Yaozhong Ding; Jonathan S. Bromberg; Spencer; Lasky
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First-line, single-agent Herceptin® (trastuzumab) in metastatic breast cancer: A preliminary report
European Journal of Cancer, ISSN: 09598049
Charles L. Vogel; Melody A. Cobleigh; Debasish Tripathy; John C. Gutheil; Lyndsay N. Harris; Louis Fehrenbacher; Dennis J. Slamon; Maureen Murphy; Novotny; Michael Burchmore; Shak; Stanford J. Stewart
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Hepatocyte growth factor enhances vascular endothelial growth factor-induced angiogenesis in vitro and in vivo
American Journal of Pathology, ISSN: 00029440
Xiaohua Xin; Suya Yang; Gladys S. Ingle; Constance Zlot; Linda Rangell; Joe Kowalski; Ralph H. Schwall; Napoleone Ferrara; Mary E. Gerritsen
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A specific molar ratio of stabilizer to protein is required for storage stability of a lyophilized monoclonal antibody
Journal of Pharmaceutical Sciences, ISSN: 00223549
Cleland; Lam; Brent Kendrick; Yang; Tzung-Horng Yang; David E. Overcashier; Brooks; Chung C. Hsu; John F. Carpenter
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Distribution and localization of CMP-N-acetylneuraminic acid hydroxylase and N-glycolylneuraminic acid-containing glycoconjugates in porcine lymph node and peripheral blood lymphocytes
European Journal of Cell Biology, ISSN: 01719335
Yanina N. Malykh; Brigitte Krisch; Lee Shaw; Warner; Sinicropi; Roanne Smith; Joseph Chang; Roland Schauer
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Validating the sanitization of chromatographic resins: A sample case study
BioPharm, ISSN: 10408304
Hiraoka-Sutow; Broughton
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The external granule layer of the developing chick cerebellum generates granule cells and cells of the isthmus and rostral hindbrain
Journal of Neuroscience, ISSN: 02706474
John C. Lin; Li Cai; Constance L. Cepko
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An improved method for the extraction of SV40 DNA for real-time quantitative PCR assay
American Biotechnology Laboratory, ISSN: 07493223
Shi; Yuan Xu
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Migrating, archiving, and reconstructing electronic records in a regulatory environment
Drug Information Journal, ISSN: 00928615
Woodrum
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Capillary Electrophoresis as a Routine Analytical Tool in Pharmaceutical Analysis
LC-GC Europe, ISSN: 14716577
Kevin D. Altria; Chen; Lilian Clohs
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Downregulation of Hedgehog signaling is required for organogenesis of the small intestine in Xenopus
Developmental Biology, ISSN: 00121606
Jian Zhang; Rosenthal; Frederic J. De Sauvage; Ramesh A. Shivdasani
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Metal-catalyzed oxidation of human growth hormone: Modulation by solvent-induced changes of protein conformation
Journal of Pharmaceutical Sciences, ISSN: 00223549
Susan W. Hovorka; Jinyang Hong; Cleland; Christian Schöneich
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Determination of a weight-adjusted dose of TNK-tissue plasminogen activator
American Heart Journal, ISSN: 00028703
Wang-Clow; Fox; Christopher P. Cannon; C.Michael Gibson; Berioli; Bluhmki; Danays; Eugene Braunwald; Frans Van De Werf; David Stump
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Characterization of EDTA-soluble polysaccharides from the scape of Musa paradisiaca (banana)
Biotechnology and Applied Biochemistry, ISSN: 08854513
T. Shantha Raju; Jagadish; Anjaneyalu
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Binding protein-3-selective insulin-like growth factor I variants: Engineering, biodistributions, and clearance
Endocrinology, ISSN: 00137227
Yves Dubaquié; Deborah L. Mortensen; Anthony Intintoli; Deborah A. Hogue; Nakamura; Rancatore; Philip M. Lester; Michael D Sadick; Ellen H. Filvaroff; Fielder; Henry B. Lowman
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Heparin coinfusion during convection-enhanced delivery (CED) increases the distribution of the glial-derived neurotrophic factor (GDNF) ligand family in rat striatum and enhances the pharmacological activity of neurturin
Experimental Neurology, ISSN: 00144886
John F. Hamilton; Paul F. Morrison; Michael Y. Chen; Judith Harvey-White; Rosario S. Pernaute; Phillips; Edward Oldfield; Krys S. Bankiewicz
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Effect of NGF and neurotrophin-3 treatment on experimental diabetic autonomic neuropathy
Journal of Neuropathology and Experimental Neurology, ISSN: 00223069
Robert E. Schmidt; Denise A. Dorsey; Lucie N. Beaudet; Curtis A. Parvin; Escandon
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Power consumption profiles in high-shear wet granulation. II: Predicting the overwetting point from a spreading energy
Journal of Pharmaceutical Sciences, ISSN: 00223549
Cleland; Lam; Brent Kendrick; Yang; Tzung-Horng Yang; David E. Overcashier; Brooks; Chung C. Hsu; John F. Carpenter
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Assays for human DNase I activity in biological matrices.
Methods in Molecular Biology, ISSN: 10643745
Sinicropi; Lazarus
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Engineered properties and assays for human DNase I mutants.
Methods in Molecular Biology, ISSN: 10643745
Clark Q. Pan; Sinicropi; Lazarus
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Selective expression of murine prostate stem cell antigen in fetal and adult tissues and the transgenic adenocarcinoma of the mouse prostate model of prostate carcinogenesis
American Journal of Pathology, ISSN: 00029440
Ross; Spencer; Lasky; Koeppen
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Leptospiral lipopolysaccharide activates cells through a TLR2-dependent mechanism
Nature Immunology, ISSN: 15292908
Catherine Werts; Richard I. Tapping; John C. Mathison; Tsung-Hsien Chuang; Vladimir Kravchenko; Saint-Girons; David A. Haake; Godowski; Fumitaka Hayashi; Adrian Ozinsky; David M. Underhill; Carsten J. Kirschning; Hermann Wagner; Alan Aderem; Peter S. Tobias; Richard J. Ulevitch
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Generation of a humanized, high affinity anti-tissue factor antibody for use as a novel antithrombotic therapeutic
Thrombosis and Haemostasis, ISSN: 03406245
Presta; Paul Sims; Meng; Paul Moran; Sherron L. Bullens; Bunting; Schoenfeld; David G Lowe; Lai; Rancatore; Iverson; Lim; Chisholm; Robert F. Kelley; Markus A. Riederer; Daniel Kirchhofer
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Terms of reference for Data and Safety Monitoring Committees
American Heart Journal, ISSN: 00028703
Milton Packer; Janet Wittes; David Stump
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Vitamin a intake affects the contribution of chylomicrons vs. Retinol-binding protein to milk vitamin A in lactating rats
Journal of Nutrition, ISSN: 00223166
Michael H. Green; Joanne Balmer Green; Sylvie A. Akohoue; Sean K. Kelley
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CD62L is required on effector cells for local interactions in the CNS to cause myelin damage in experimental allergic encephalomyelitis
Immunity, ISSN: 10747613
Iqbal S. Grewal; Harald G. Foellmer; Kate D. Grewal; Hua Wang; Wyne P. Lee; Daniel B. Tumas; Charles A. Janeway Jr.; Richard A. Flavell
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Induction of gp91-phox, a component of the phagocyte NADPH oxidase, in microglial cells during central nervous system inflammation
Journal of Cerebral Blood Flow and Metabolism, ISSN: 0271678X
Green; Cairns; Julie Rae; Errett-Baroncini; Hongo; Erickson; John T. Curnutte
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Concordance for Type 1 Diabetes in Identical Twins Is Affected by Insulin Genotype
Diabetes Care, ISSN: 01495992
Karl A. Metcalfe; Graham A. Hitman; Rachel E. Rowe; Mohammed Hawa; Huang; Stewart; R. David G. Leslie
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Matrix-assisted laser desorption/ionization time-of-flight mass analysis of peptides.
Current protocols in protein science / editorial board, John E. Coligan ... [et al.], ISSN: 19343663
William J. Henzel; Stults
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Acute coronary syndromes
Annals of Emergency Medicine, ISSN: 01960644
Thomas Aufderheide; Leo L. Bossaert; John Field; Johan Herlitz; Alain Leizorovicz; Katherine A. Littrell; Joseph P. Ornato; Mary Ann Peberdy; Flavio Ribichini
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