Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 11851 - 11900 OF 15583 RESULTS

Do nerve growth factor-related mechanisms contribute to loss of cutaneous nociception in leprosy?
Pain, ISSN: 03043959
Paul Facer; Dawn Mann; Rajeev Mathur; Shubha Pandya; Uma Ladiwala; Bhim Singhal; Hongo; Sinicropi; Giorgio Terenghi; Anand
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Receptor-binding conformation of the 'ELR' motif of IL-8: X-ray structure of the L5C/H33C variant at 2.35 Å resolution
Proteins: Structure, Function and Bioinformatics, ISSN: 08873585
Nancy Gerber; Henry B. Lowman; Dean R. Artis; Eigenbrot
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Oncogenic Raf-1 disrupts epithelial tight junctions via downregulation of occludin
Journal of Cell Biology, ISSN: 00219525
Danxi Li; Mrsny
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Comparison of three treatment options for single brain metastasis from lung cancer
International Journal of Cancer, ISSN: 00207136
Jun Itakura; Toshiyuki Ishiwata; Shen; Marko Kornmann; Murray Korc
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Convergent solutions to binding at a protein-protein interface
Science, ISSN: 00368075
Warren L. DeLano; Ultsch; De Vos; James A. Wells
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High copy display of large proteins on phage for functional selections
Journal of Molecular Biology, ISSN: 00222836
Sachdev S. Sidhu; Gregory A. Weiss; James A. Wells
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Increased death receptor 5 expression by chemotherapeutic agents in human gliomas causes synergistic cytotoxicity with tumor necrosis factor- related apoptosis-inducing ligand in vitro and in vivo
Cancer Research, ISSN: 00085472
Motoo Nagane; Pan; Jessie J. Weddle; Vishva M. Dixit; Cavenee; Su Huang
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Assessment of the myotoxicity of pharmaceutical buffers using an in vitro muscle model: Effect of pH, capacity, tonicity, and buffer type
Pharmaceutical Development and Technology, ISSN: 10837450
Jintana Napaporn; Maike Thomas; Kari A. Svetic; Shahrokh; Gayle A. Brazeau
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Src-like adaptor protein (SLAP) is a negative regulator of T cell receptor signaling
Journal of Experimental Medicine, ISSN: 00221007
Tomasz Sosinowski; Akhilesh Pandey; Vishva M. Dixit; Arthur Weiss
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Simian virus 40 large T antigen binds a novel Bcl-2 homology domain 3- containing proapoptosis protein in the cytoplasm
Journal of Biological Chemistry, ISSN: 00219258
Shih-Chong Tsai; Kishore B. S. Pasumarthi; Laura Pajak; Michael Franklin; Brian Patton; He Wang; William J. Henzel; Stults; Loren J. Field
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Long-term survival update for high-dose recombinant interleukin-2 in patients with renal cell carcinoma
Cancer Journal from Scientific American, ISSN: 10814442
Richard I. Fisher; Steven A. Rosenberg; Gwendolyn Fyfe
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Transient focal cerebral ischemia induces sensorimotor deficits in mice
Behavioural Brain Research, ISSN: 01664328
Gerlai; Harold Thibodeaux; James T. Palmer; Menno Van Lookeren Campagne; Nicholas Van Bruggen
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Isolation and characterization of CRF-related diuretic hormones from the whitelined sphinx moth Hyles lineata
Insect Biochemistry and Molecular Biology, ISSN: 09651748
Kenji Furuya; Marilyn A. Harper; Kathleen M. Schegg; David A. Schooley
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High-dose recombinant interleukin-2 therapy in patients with metastatic melanoma: Long-term survival update
Cancer Journal from Scientific American, ISSN: 10814442
Michael B. Atkins; Lori Kunkel; Mario Sznol; Steven A. Rosenberg
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Intracranial hemorrhage rates and effect of immediate beta-blocker use in patients with acute myocardial infarction treated with tissue plasminogen activator
American Journal of Cardiology, ISSN: 00029149
Hal V. Barron; Amy Chen Rundle; Joel M. Gore; Jerry H. Gurwitz; Jan Penney
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Brain-derived neurotrophic factor induces excitotoxic sensitivity in cultured embryonic rat spinal motor neurons through activation of the phosphatidylinositol 3-kinase pathway
Journal of Neurochemistry, ISSN: 00223042
Hugh J. L. Fryer; Daniel H. Wolf; Ronald J. Knox; Stephen M. Strittmatter; Diane Pennica; O'Leary; David S. Russell; Robert G. Kalb
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Green fluorescent protein as a second selectable marker for selection of high producing clones from transfected CHO cells
Gene, ISSN: 03781119
Meng; Jie Liang; Wai Lee T. Wong; Chisholm
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Cytokine-induced nuclear factor kappa B activation promotes the survival of developing neurons
Journal of Cell Biology, ISSN: 00219525
Gayle Middleton; Makoto Hamanoue; Yasushi Enokido; Sean Wyatt; Diane Pennica; Ellis Jaffray; Ronald T. Hay; Alun M. Davies
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Coarse spray delivery to a localized region of the pulmonary airways for gene therapy
Human Gene Therapy, ISSN: 10430342
Cipolla; Gonda; Steven Shak; Kovesdi; Crystal; Sweeney
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Cloning and characterization of IL-17B and IL-17C, two new members of the IL-17 cytokine family
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Hanzhong Li; Jian Chen; Arthur Huang; Stinson; Sherry Heldens; Foster; Patrick Dowd; Austin L. Gurney; William I. Wood
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RGD mimetics containing a central hydantoin scaffold: α(v)β3 vs α(IIb)β3 selectivity requirements
Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X
Peyman; Volkmar Wehner; Knolle; Stilz; Breipohl; Karl-Heinz Scheunemann; Denis Carniato; Ruxer; Gourvest; Thomas Gadek; Bodary
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A highly conserved enhancer in the Dlx5/Dlx6 intergenic region is the site of cross-regulatory interactions between Dlx genes in the embryonic forebrain
Journal of Neuroscience, ISSN: 02706474
Ted Zerucha; Thorsten Stühmer; Gary Hatch; Byung K. Park; Qiaoming Long; Guoying Yu; Adrianna Gambarotta; Joshua R. Schultz; John L. R. Rubenstein; Marc Ekker
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Kistrin inhibits human smooth muscle cell interaction with fibrin
Thrombosis Research, ISSN: 00493848
Karen O Yee; Yuji Ikari; Bodary; Schwartz
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Characterization of the binding interface between the E-domain of Staphylococcal protein A and an antibody Fv-fragment
Biochemistry, ISSN: 00062960
David Meininger; Mark Rance; Melissa A. Starovasnik; Wayne J. Fairbrother; Nicholas J. Skelton
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Comparison of the rates of deamidation, diketopiperazine formation, and oxidation in recombinant human vascular endothelial growth factor and model peptides
AAPS PharmSci, ISSN: 15221059
Chimanlall Goolcharran; Andrew J.S. Jones; Ronald T. Borchardt; Cleland; Rodney Keck
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Drug information in industry versus academia: A pharmacy resident's perspective of a sample case
Therapeutic Innovation and Regulatory Science, ISSN: 21684790
Graham; David A. Graves; Barry Grobman; Gary M. Mccart; Candy Tsourounis
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Purification of yeast mitochondrial Hsp60.
Methods in Molecular Biology, ISSN: 10643745
Yves Dubaquié; Renate Looser; Sabine Rospert
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Mice lacking α-synuclein display functional deficits in the nigrostriatal dopamine system
Neuron, ISSN: 08966273
Asa Abeliovich; Yvonne Schmitz; Isabel Fariñas; Choi-Lundberg; Ho; Pablo E. Castillo; Natasha Shinsky; Jose Manuel Garcia-Verdugo; Armanini; Anne Ryan; Mary Hynes; Phillips; David Sulzer; Rosenthal
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Pharmacokinetics and pharmacodynamics of tenecteplase: Results from a phase II study in patients with acute myocardial infarction
Journal of Clinical Pharmacology, ISSN: 00912700
Modi; Fox; Fong-Wong Clow; Tanswell; Christopher P. Cannon; Frans Van De Werf; Eugene Braunwald
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Toll-like receptor 2-mediated NF-κB activation requires a Rac I-dependent pathway
Nature Immunology, ISSN: 15292908
Laurence Arbibe; Jean-Paul Mira; Nicole Teusch; Lois Kline; Mausumee Guha; Nigel Mackman; Godowski; Richard J. Ulevitch; Ulla G. Knaus
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Gene expression profiling in an in vitro model of angiogenesis
American Journal of Pathology, ISSN: 00029440
Jeanne Kahn; Fuad Mehraban; Gladys S. Ingle; Xiaohua Xin; Juliet E. Bryant; Gordon A. Vehar; Schoenfeld; Grimaldi; Franklin V. Peale Jr.; Aparna Draksharapu; Lewin; Mary E. Gerritsen
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Clonidine for smoking cessation.
Cochrane database of systematic reviews (Online : Update Software), ISSN: 1469493X
Steven G. Gourlay; Stead; Neal L. Benowitz
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The nucleoskeleton: Go EAST, young man
Nature Cell Biology, ISSN: 14657392
Lasky
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The seven-transmembrane receptor Smoothened cell-autonomously induces multiple ventral cell types
Nature Neuroscience, ISSN: 10976256
Mary Hynes; Weilan Ye; Kevin Wang; Donna Stone; Maximilien Murone; Frederic J. De Sauvage; Rosenthal
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Angiography of fluoresceinated anti-vascular endothelial growth factor antibody and dextrans in experimental choroidal neovascularization
Archives of Ophthalmology, ISSN: 00039950
Michael J. Tolentino; Deeba Husain; Panagiotis Theodosiadis; Evangelos S. Gragoudas; Edward Connolly; Jeanne Kahn; Cleland; Anthony P. Adamis; R. Andrew Cuthbertson; Joan W. Miller
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Analysis of PTCH/SMO/SHH pathway genes in medulloblastoma
Genes Chromosomes and Cancer, ISSN: 10452257
Russell H. Zurawel; Cory Allen; Sharon Chiappa; Walter Cato; Jaclyn Biegel; Philip Cogen; Frederic J. De Sauvage; Corey Raffel
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Concomitant over-expression of vascular endothelial growth factor and its receptors in pancreatic cancer
International Journal of Cancer, ISSN: 00207136
Jun Itakura; Toshiyuki Ishiwata; Shen; Marko Kornmann; Murray Korc
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Role of the distal half of the c-Mpl intracellular domain in control of platelet production by thrombopoietin in vivo
Molecular and Cellular Biology, ISSN: 02707306
Shiuh-Ming Luoh; Stefanich; Gregg Solar; Hope Steinmetz; Michael T. Lipari; Tamara I. Pestina; Carl W. Jackson; Frederic J. De Sauvage
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Growth hormone safety update from the National Cooperative Growth Study
Journal of Pediatric Endocrinology and Metabolism, ISSN: 0334018X
Thomas J. Maneatis; Joyce Baptista; Connelly; Sandra L. Blethen
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APO2L/TRAIL expression in human brain tumors
Acta Neuropathologica, ISSN: 00016322
Mitsutoshi Nakamura; Johannes Rieger; Michael Weller; Jin Kim; Paul Kleihues; Hiroko Ohgaki
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A reversed-phase HPLC assay for plasminogen activators
Journal of Liquid Chromatography and Related Technologies, ISSN: 10826076
Yuan Xu; Cacia
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The importance of growth hormone replacement therapy for bone mass in young adults with growth hormone deficiency
Journal of Pediatric Endocrinology and Metabolism, ISSN: 0334018X
Kenneth M. Attie
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The glial cell line-derived neurotrophic factor family receptor components are differentially regulated within sensory neurons after nerve injury
Journal of Neuroscience, ISSN: 02706474
David L. H. Bennett; Timothy J. Boucher; Armanini; Kris Poulsen; Gregory J. Michael; John V. Priestley; Phillips; McMahon; David L. Shelton
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The 2.0 Å structure of bovine interferon-γ; assessment of the structural differences between species
Acta Crystallographica Section D: Biological Crystallography, ISSN: 09074449
Michael Randal; Anthony A. Kossiakoff
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Putting the pieces together: contribution of fluorescence polarization assays to small molecule lead optimization
Proceedings of SPIE - The International Society for Optical Engineering, ISSN: 0277786X
Keating; James C. Marsters Jr.; Beresini; Ladner; Kimberly Zioncheck; Clark; Arellano; Bodary
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Targeting genes and proteins in the analysis of learning and memory: Caveats and future directions
Reviews in the Neurosciences, ISSN: 03341763
Gerlai
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WECHE: A novel hematopoietic regulatory factor
Immunity, ISSN: 10747613
Osamu Ohneda; Kinuko Ohneda; Hisayuki Nomiyama; Zhong Zheng; Steven A. Gold; Fumio Arai; Takeshi Miyamoto; Bruce E. Taillon; Richard A. McIndoe; Richard A. Shimkets; Lewin; Toshio Suda; Lasky
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Web Alert. Apoptosis.
Chemistry and Biology, ISSN: 10745521
Eric W. Humke
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Substrate-assisted catalysis: Molecular basis and biological significance
Protein Science, ISSN: 09618368
William Dall'Acqua; Paul J. Carter
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Use of phage display for the generation of human antibodies that neutralize factor IXa function
Blood Coagulation and Fibrinolysis, ISSN: 09575235
Shelley Suggett; Daniel Kirchhofer; Hass; Michael T. Lipari; Paul Moran; Nagel; Judice; Kurt A. Schroeder; Jeffrey Tom; Henry B. Lowman; Adams; Dan L. Eaton; Devaux
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