Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 12051 - 12100 OF 15701 RESULTS

Experimental histoplasmosis in mice treated with anti-murine interferon- γ antibody and in interferon-γ gene knockout mice
Microbes and Infection, ISSN: 12864579
Karl V. Clemons; Darbonne; John T. Curnutte; Raymond A. Sobel; David A. Stevens
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Impact of endotoxin on UCP homolog mRNA abundance, thermoregulation, and mitochondrial proton leak kinetics
American Journal of Physiology - Endocrinology and Metabolism, ISSN: 01931849
Yu; Jamie L. Barger; Bert B. Boyer; Martin D. Brand; Pan; Adams
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Mapping the phosphorylation sites of proteins using on-line immobilized metal affinity chromatography/capillary electrophoresis/electrospray ionization multiple stage tandem mass spectrometry
Rapid Communications in Mass Spectrometry, ISSN: 09514198
Ping Cao; Stults
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Combining enhanced metabolic labeling with immunoblotting to detect interactions of endogenous cellular proteins
BioTechniques, ISSN: 07366205
Frank C. Kischkel; Avi Ashkenazi
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The effects of a histidine residue on the C-terminal side of an asparaginyl residue on the rate of deamidation using model pentapeptides
Journal of Pharmaceutical Sciences, ISSN: 00223549
Chimanlall Goolcharran; Lori L. Stauffer; Cleland; Ronald T. Borchardt
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Anti-VEGF antibody treatment of glioblastoma prolongs survival but results in increased vascular cooption
Neoplasia (United States), ISSN: 15228002
James L. Rubenstein; Jin Kim; Tomoko Ozawa; Michael Zhang; Manfred Westphal; Dennis F. Deen; Shuman
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VEGF enhances angiogenesis and promotes blood-brain barrier leakage in the ischemic brain
Journal of Clinical Investigation, ISSN: 00219738
Zheng Gang Zhang; Li Zhang; Quan Jiang; Ruilan Zhang; Kenneth Davies; Cecylia Powers; Nicholas Van Bruggen; Michael Chopp
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Anticalins versus antibodies: Made-to-order binding proteins for small molecules
Chemistry and Biology, ISSN: 10745521
Gregory A. Weiss; Henry B. Lowman
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Consequences of inhibition of plasma carboxypeptidase B on in vivo thrombolysis, thrombosis and hemostasis
Fibrinolysis and Proteolysis, ISSN: 13690191
Refino; Leo Deguzman; Schmitt; Rowena Smyth; Surinc Er Jeet; Michael T. Lipari; Dan L. Eaton; Bunting
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Translation and linguistic validation of a disease-specific quality of life measure for cystic fibrosis
Journal of Pediatric Psychology, ISSN: 01468693
Alexandra L. Quittner; Sheri Sweeny; Marc Watrous; Paul Munzenberger; Karen Bearss; Amy Gibson Nitza; Lisa A. Fisher; Bernadette Henry
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Magnetic resonance imaging in an experimental model of human ovarian cancer demonstrating altered microvascular permeability after inhibition of vascular endothelial growth factor
American Journal of Obstetrics and Gynecology, ISSN: 00029378
Axel Gossmann; Thomas H. Helbich; Sam Mesiano; David M. Shames; Michael F. Wendland; Timothy P.L. Roberts; Napoleone Ferrara; Robert B. Jaffe; Robert C. Brasch
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Effect of zinc binding and precipitation on structures of recombinant human growth hormone and nerve growth factor
Journal of Pharmaceutical Sciences, ISSN: 00223549
Tzung-Horng Yang; Cleland; Lam; Jeffrey D. Meyer; Latoya S. Jones; Theodore W. Randolph; Mark C. Manning; John F. Carpenter
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Augmented expression of cardiotrophin-1 and its receptor component, gp130, in both left and right ventricles after myocardial infarction in the rat
Journal of Molecular and Cellular Cardiology, ISSN: 00222828
Takeshi Aoyama; Yoshihito Takimoto; Diane Pennica; Reiko Inoue; Eiji Shinoda; Ryuichi Hattori; Yoshiki Yui; Shigetake Sasayama
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Prehospital and emergency department delays after acute stroke: The genentech stroke presentation survey
Stroke, ISSN: 00392499
Dexter L. Morris; Wayne Rosamond; Kenneth Madden; Carol Schultz; Scott Hamilton
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High dose recombinant human growth hormone (GH) treatment of GH-deficient patients in puberty increases near-final height: A randomized, multicenter trial
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X
Kenneth M. Attie; Joyce Baptista; Gilbert P. August; Jennifer J. Bell; Foley; Ronald W. Gotlin; Madeleine D. Harbison; Hintz; Hopwood; Margaret H. Macgillivray; Nelly Mauras; Wayne V. Moore; Thomas Moshang Jr.; Parker; Plotnick; Edward O. Reiter; Alan D. Rogol; William E. Russell; Saenger; Styne; Thomas A. Wilson; David T. Wyatt
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Real-time quantitative PCR for retrovirus-like particle quantification in CHO cell culture
Biologicals, ISSN: 10451056
Christina De Wit; Fautz; Yuan Xu
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Effects of exercise training on cardiac function, gene expression, and apoptosis in rats
American Journal of Physiology - Heart and Circulatory Physiology, ISSN: 03636135
Hongkui Jin; Renhui Yang; Wei Li; Hsienwie Lu; Anne Ryan; Annie Ogasawara; John Van Peborgh; Nicholas F. Paoni
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A Phase I Trial of Recombinant Human Thrombopoietin in Patients With Delayed Platelet Recovery After Hematopoietic Stem Cell Transplantation
Biology of Blood and Marrow Transplantation, ISSN: 10838791
Richard A. Nash; Razelle Kurzrock; John DiPersio; Julie Vose; Charles Linker; Dipnarine Maharaj; Auayporn P. Nademanee; Robert Negrin; Stephen Nimer; Howard Shulman; Ashby; Jones Jr.; Frederick R. Appelbaum; Richard Champlin
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Controlled drug delivery: Present and future
ACS Symposium Series, ISSN: 00976156
Kinam Park; Mrsny
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Hepatocyte growth factor and vitamin D cooperatively inhibit androgen-unresponsive prostate cancer cell lines
Endocrinology, ISSN: 00137227
Laila R. Qadan; Carlos M. Perez-Stable; Ralph H. Schwall; Kerry L. Burnstein; Richard C. Ostenson; Guy A. Howard; Bernard A. Roos
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Noninvasive in vivo analysis of human small intestinal paracellular absorption: Regulation by Na+-glucose cotransport
Digestive Diseases and Sciences, ISSN: 01632116
Turner; Cohen; Mrsny; James L. Madara
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Modulation of allergic inflammation in mice deficient in TNF receptors
American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN: 10400605
Daniel G. Rudmann; Mark Moore; Tepper; Melinda C. Aldrich; Juergen W. Pfeiffer; Harm Hogenesch; Daniel B. Tumas
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Epitope location on tissue factor determines the anticoagulant potency of monoclonal anti-tissue factor antibodies
Thrombosis and Haemostasis, ISSN: 03406245
Daniel Kirchhofer; Paul Moran; Nancy Y. Chiang; Kim; Markus A. Riederer; Eigenbrot; Robert F. Kelley
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Structure and expression of a membrane component of the inhibin receptor system
Endocrinology, ISSN: 00137227
Huira Chong; Stephanie A. Pangas; Daniel J. Bernard; Eileen Wang; Jolee Gitch; Wei Chen; Lawrence B. Draper; Edward T. Cox; Woodruff
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Cytoskeletal protein PSTPIP1 directs the PEST-type protein tyrosine phosphatase to the c-Abl kinase to mediate Abl dephosphorylation
Molecular Cell, ISSN: 10972765
Feng Cong; Spencer; Jean-François Côté; Yan Wu; Michel L. Tremblay; Lasky; Stephen P. Goff
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Characterization of Novel Neutralizing Monoclonal Antibodies Specific to Human Neurturin
Hybridoma, ISSN: 0272457X
Jo-Anne S. Kongo; Siao Ping Tsai; Moffat; Kurt A. Schroeder; Chris Jung; Anan Chuntharapai; Patricia A. Lampe; Eugene M. Johnson Jr.; Frederic J. De Sauvage; Armanini; Phillips; Devaux
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Nonparametric estimation of a periodic function
Biometrika, ISSN: 00063444
Peter Hall; Reimann; John Rice
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Amino acid analysis, using postcolumn ninhydrin detection, in a biotechnology laboratory.
Methods in Molecular Biology, ISSN: 10643745
Frank D. Macchi; Felicity J. Shen; Rodney Keck; Reed J. Harris
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A neutralizing monoclonal antibody specific for the dimer interface region of IL-8
Cytokine, ISSN: 10434666
Laura DeForge; Henry B. Lowman; Leong; Anan Chuntharapai; Jin Kim; Hébert
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Cardiotrophin-1 reduces stress-induced heat shock protein production in cardiac myocytes
Cytokine, ISSN: 10434666
Julia Railson; Kevin Lawrence; Anastatis Stephanou; Bhawanjit K. Brar; Diane Pennica; David S. Latchman
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Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5
Immunity, ISSN: 10747613
Frank C. Kischkel; David Lawrence; Anan Chuntharapai; Peter Schow; K.Jin Kim; Avi Ashkenazi
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T-wave alternans and serious ventricular arrhythmias: A tale of two T-waves
Journal of the American College of Cardiology, ISSN: 07351097
Hal V. Barron
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Pharmacokinetics and pharmacodynamics of sibrafiban, an orally administered GP IIb/IIIa antagonist, following coadministration of aspirin and heparin
Journal of Clinical Pharmacology, ISSN: 00912700
Reimann; Modi; Novotny
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Embryonic stem cells go dopaminergic
Neuron, ISSN: 08966273
Mary Hynes; Rosenthal
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Characterization of huJAM: Evidence for involvement in cell-cell contact and tight junction regulation
American Journal of Physiology - Cell Physiology, ISSN: 03636143
Tony W. Liang; Richard A. Demarco; Mrsny; Austin L. Gurney; Gray; Jeff Hooley; Holly L. Aaron; Arthur Huang; Toni Klassen; Daniel B. Tumas; Sherman Fong
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VEGF: An update on biological and therapeutic aspects
Current Opinion in Biotechnology, ISSN: 09581669
Napoleone Ferrara
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Identification of paracaspases and metacaspases: Two ancient families of caspase-like proteins, one of which plays a key role in MALT lymphoma
Molecular Cell, ISSN: 10972765
Anthony G. Uren; Karen M. O'Rourke; Aravind; Pisabarro; Somasekar Seshagiri; Eugene V. Koonin; Vishva M. Dixit
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Pharmaceutical biotechnology the genomes are just the beginning: Editorial overview
Current Opinion in Biotechnology, ISSN: 09581669
Lawn; Lasky
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Phage display in pharmaceutical biotechnology
Current Opinion in Biotechnology, ISSN: 09581669
Sachdev S. Sidhu
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Characterization of huJAM: Evidence for involvement in cell-cell contact and tight junction regulation
American Journal of Physiology - Cell Physiology, ISSN: 03636143
Tony W. Liang; Richard A. Demarco; Mrsny; Austin L. Gurney; Gray; Jeff Hooley; Holly L. Aaron; Arthur Huang; Toni Klassen; Daniel B. Tumas; Fong
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Treatment of allergic asthma with monoclonal anti-IgE antibody
New England Journal of Medicine, ISSN: 00284793
Henry Milgrom; Robert B. Fick Jr.; John Q. Su; Reimann; Robert K. Bush; Marc Watrous; W. James Metzger
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Expression of activated CDC42 induces T cell apoptosis in thymus and peripheral lymph organs via different pathways
Oncogene, ISSN: 09509232
Songqing Na; Baiyong Li; Iqbal S. Grewal; Hervé Enslen; Roger J. Davis; Jeffrey H. Hanke; Richard A. Flavell
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Functional interaction between Gα(z) and Rap1GAP suggests a novel form of cellular cross-talk
Journal of Biological Chemistry, ISSN: 00219258
Jingwei Meng; Jennifer L. Glick; Paul G. Polakis; Patrick J. Casey
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Baculovirus-based genetic screen for antiapoptotic genes identifies a novel IAP
Journal of Biological Chemistry, ISSN: 00219258
Somasekar Seshagiri; Domagoj Vucic; James Lee; Vishva M. Dixit
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Autosomal recessive chronic granulomatous disease caused by novel mutations in NCF-2, the gene encoding the p67-phox component of phagocyte NADPH oxidase
Human Genetics, ISSN: 03406717
Noack; Julie Rae; Andrew R. Cross; José Muñoz; Siham Salmen; José A. Mendoza; Nineth Rossi; John T. Curnutte; Heyworth
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Overexpression of thioredoxin h leads to enhanced activity of starch debranching enzyme (pullulanase) in barley grain
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Myeong-Je Cho; Joshua H. Wong; Corina Marx; Jiang; Peggy G. Lemaux; Bob B. Buchanan
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Development of bivalent (B/E) vaccines able to neutralize CCR5-dependent viruses from the United States and Thailand
Virology, ISSN: 00426822
Berman; Wei Huang; Riddle; Gray; Wrin; Vennari; Johnson; Michael Klaussen; Prashad; Christiane Köhne; Christina De Wit; Timothy Gregory
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Validation of a rat pheochromocytoma (PC12)-based cell survival assay for determining biological potency of recombinant human nerve growth factor
Journal of Pharmaceutical and Biomedical Analysis, ISSN: 07317085
Hélène Gazzano-Santoro; Chen; Barbara Casto; Chu; Ellen Gilkerson; Mukku; Eleanor Canova-Davis; Claire Kotts
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Secretion of glycosylation site mutants can be rescued by the signal/pro sequence of tissue plasminogen activator
Journal of Cellular Biochemistry, ISSN: 07302312
Christiane Köhne; Johnson; Sabrina Tom; Peers; Richard L. Gehant; Hotaling; Dave Brousseau; Thomas Ryll; Judy Fox; Steven M. Chamow; Berman
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Recombinant tissue-type plasminogen activator (Alteplase) for ischemic stroke 3 to 5 hours after symptom onset the ATLANTIS study: A randomized controlled trial
JAMA - Journal of the American Medical Association, ISSN: 00987484
Wayne M. Clark; Stanley Wissman; Gregory W. Albers; Jack H. Jhamandas; Kenneth Madden; Scott Hamilton
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