Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 12201 - 12250 OF 15701 RESULTS

June 10, 1999

The toll of innate immunity on microbial pathogens

New England Journal of Medicine, ISSN: 00284793

Robert L. Modlin; Hans D. Brightbill; Godowski

June 5, 1999

Lack of developmental neurotoxicity of MN rgp120/HIV-1 administered subcutaneously to neonatal rats

Toxicological Sciences, ISSN: 10966080

Bussiere; Laurel M. Hardy; Peterson; John A. Foss; Robert H. Garman; Alan M. Hoberman; Mildred S. Christian

June 1, 1999

VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation

Nature Medicine, ISSN: 10788956

Hans-Peter Gerber; Thiennu H. Vu; Anne Ryan; Joe Kowalski; Zena Werb; Napoleone Ferrara

June 1, 1999

A dynamic film model for ultrafiltration

Journal of Membrane Science, ISSN: 03767388

Perkins; Saksena; Van Reis

June 1, 1999

Identification of a human anti-CD55 single-chain Fv by subtractive panning of a phage library using tumor and nontumor cell lines

Cancer Research, ISSN: 00085472

John B.B. Ridgway; Eric Ng; Jeffrey Kern; James Lee; Brush; Goddard; Paul J. Carter

June 1, 1999

Signalling by the RET receptor tyrosine kinase and its role in the development of the mammalian enteric nervous system

Development (Cambridge), ISSN: 09501991

Stavros Taraviras; Camelia V. Marcos-Gutierrez; Pascale Durbec; Harsha Jani; Maria Grigoriou; Madhu Sukumaran; Li-Chong Wang; Mary Hynes; Geoffrey Raisman; Vassilis Pachnis

June 1, 1999

The effect of O-fucosylation on the first EGF-like domain from human blood coagulation factor VII

Biochemistry, ISSN: 00062960

Yung-Hsiang Kao; Geoffrey F. Lee; Yang Wang; Melissa A. Starovasnik; Robert F. Kelley; Spellman; Laura Lerner

June 1, 1999

A low-volume, short-path length dynamic light scattering sample cell for highly turbid suspensions

Analytical Biochemistry, ISSN: 00032697

Thomas W. Patapoff; Travis H. Tani; Cromwell

June 1, 1999

The effect of O-fucosylation on the first EGF-like domain from human blood coagulation factor VII

Biochemistry, ISSN: 00062960

Kao; Geoffrey F. Lee; Yang Wang; Melissa A. Starovasnik; Robert F. Kelley; Spellman; Laura Lerner

May 28, 1999

Simultaneous presence of p47(phox) and flavocytochrome b-245 are required for the activation of NADPH oxidase by anionic amphiphiles: Evidence for an intermediate state of oxidase activation

Journal of Biological Chemistry, ISSN: 00219258

Andrew R. Cross; Erickson; John T. Curnutte

May 28, 1999

UC-genentech trial [1] (multiple letters)

Science, ISSN: 00368075

Henner; David V. Goeddel; Herbert Heyneker; Itakura Keiichi; Yansura; Ross; Miozzari; Peter H. Seeburg

May 27, 1999

Genentech stands by original data [3]

Nature, ISSN: 00280836

Henner; David V. Goeddel; Herbert Heyneker; Itakura Keiichi; Yansura; Ross; Miozzari

May 22, 1999

A two-dimensional protein map of Chinese hamster ovary cells

Electrophoresis, ISSN: 01730835

Kathleen M. Champion; David Arnott; William J. Henzel; Sam Hermes; Weikert; Stults; Vanderlaan; Lynne Krummen

May 19, 1999

Structural basis for the binding specificity of a SSTR1-Selective analog of somatostatin

Biochemical and Biophysical Research Communications, ISSN: 0006291X

Longchuan Chen; Carl Hoeger; Jean Rivier; V. Danial Fitzpatrick; Richard L. Vandlen; Armen H. Tashjian Jr.

May 18, 1999

Total alanine-scanning mutagenesis of insulin-like growth factor I (IGF- I) identifies differential binding epitopes for IGFBP-1 and IGFBP-3

Biochemistry, ISSN: 00062960

Yves Dubaquié; Henry B. Lowman

May 17, 1999

Insulin-like growth factor I regulates renal development in rodents

Developmental Genetics, ISSN: 0192253X

Sharon A. Rogers; Powell-Braxton; Marc R. Hammerman

May 17, 1999

Performance of sonication and microfluidization for liquid-liquid emulsification

Pharmaceutical Development and Technology, ISSN: 10837450

Maa; Chung C. Hsu

May 17, 1999

Cultivation of Tetrahymena thermophila in a 1.5-m3 airlift bioreactor

Applied Microbiology and Biotechnology, ISSN: 01757598

Hellenbroich; Ulrich Valley; Thomas Ryll; Roland Wagner; Tekkanat; Kessler; Roß; Deckwer

May 15, 1999

TRAIL (Apo-2L) and TRAIL receptors in human placentas: Implications for immune privilege

Journal of Immunology, ISSN: 00221767

Teresa A. Phillips; Jian Ni; Pan; Steven M. Ruben; Ying-Fei Wei; Judith L. Pace; Joan S. Hunt

May 15, 1999

Development and validation of real-time quantitative reverse transcriptase-polymerase chain reaction for monitoring gene expression in cardiac myocytes in vitro

Analytical Biochemistry, ISSN: 00032697

Jane Winer; Chris Jung; Irene Shackel; P. Mickey Williams

May 14, 1999

Purification and quantitation of tumor necrosis factor receptor immunoadhesin using a combination of immunoaffinity and reversed-phase chromatography

Journal of Chromatography B: Biomedical Sciences and Applications, ISSN: 13872273

John E. Battersby; Vanderlaan; Andrew J.S. Jones

May 1, 1999

Purification of CMP-N-acetylneuraminic acid synthetase from bovine anterior pituitary glands

Glycobiology, ISSN: 09596658

Justine Vionnet; Nelydia Conception; Warner; Gerardo Zapata; John Hanover; Williie F. Vann

May 1, 1999

Kinase receptor activation (KIRA): A rapid and accurate alternative to end-point bioassays

Journal of Pharmaceutical and Biomedical Analysis, ISSN: 07317085

Michael D Sadick; Anthony Intintoli; Quarmby; April McCoy; Eleanor Canova-Davis; Victor Ling

May 1, 1999

Down-regulation of human basophil IgE and FCεRIα surface densities and mediator release by anti-IgE-infusions is reversible in vitro and in vivo

Journal of Immunology, ISSN: 00221767

Sarbjit S. Saini; Donald W. Macglashan Jr.; Sherry A. Sterbinsky; Alkis Togias; Daniel C. Adelman; Lawrence M. Lichtenstein; Bruce S. Bochner

May 1, 1999

Sensitization of AIDS-Kaposi's sarcoma cells to Apo-2 ligand-induced apoptosis by actinomycin D

Journal of Immunology, ISSN: 00221767

Shunsuke Mori; Kaoru Murakami-Mori; Shuji Nakamura; Avi Ashkenazi; Benjamin Bonavida

May 1, 1999

Platelet glycoprotein IIb/IIIa inhibition by Lamifiban reduces the neointimal response to angioplasty in a porcine model

Heart, ISSN: 13556037

Chico; Gunn; Arnold; Sherron L. Bullens; Bunting; Cumberland; Crossman

April 29, 1999

Aberrant metabolic sialylation of recombinant proteins expressed in Chinese hamster ovary cells in high productivity cultures

Biochemical and Biophysical Research Communications, ISSN: 0006291X

Santell; Thomas Ryll; Etcheverry; Michael Santoris; George Dutina; Angie Wang; Jane Gunson; Warner

April 26, 1999

Real-time monitoring of recombinant antibody breakthrough during protein a affinity chromatography

Biotechnology and Applied Biochemistry, ISSN: 08854513

Fahrner; Gregory S. Blank

April 15, 1999

Mutations in the zebrafish unmask shared regulatory pathways controlling the development of catecholaminergic neurons

Developmental Biology, ISSN: 00121606

Guo; Stephen W. Wilson; Sam Cooke; Ajay B. Chitnis; Wolfgang Driever; Rosenthal

April 15, 1999

A randomized trial of high- versus low-dose subcutaneous interleukin-2 outpatient therapy for early human immunodeficiency virus type 1 infection

Journal of Infectious Diseases, ISSN: 00221899

Richard T. Davey Jr.; Doreen G. Chaitt; Jeffrey M. Albert; Stephen C. Piscitelli; Joseph A. Kovacs; Robert E. Walker; Judith Falloon; Michael A. Polis; Julia A. Metcalf; Henry Masur; Robin Dewar; Michael Baseler; Gwendolyn Fyfe; Martin A. Giedlin; Clifford Lane

April 13, 1999

IGF-I deficient mice show reduced peripheral nerve conduction velocities and decreased axonal diameters and respond to exogenous IGF-I treatment

Journal of Neurobiology, ISSN: 00223034

Gao; Natasha Shinsky; Gladys S. Ingle; Klaus D. Beck; Kathleen A. Elias; Powell-Braxton

April 13, 1999

Vaccination with the extracellular domain of p185(neu) prevents mammary tumor development in neu transgenic mice

Cancer Immunology, Immunotherapy, ISSN: 03407004

Laura J. Esserman; Theresa Lopez; Ruben Montes; Bald; Brian M. Fendly; Michael J. Campbell

April 9, 1999

NSP1 defines a novel family of adaptor proteins linking integrin and tyrosine kinase receptors to the c-Jun N-terminal kinase/stress-activated protein kinase signaling pathway

Journal of Biological Chemistry, ISSN: 00219258

Yanmei Lu; Brush; Stewart

April 9, 1999

mE10, a novel caspase recruitment domain-containing proapoptotic molecule

Journal of Biological Chemistry, ISSN: 00219258

Minhong Yan; James Lee; Sarah Schilbach; Goddard; Vishva M. Dixit

April 2, 1999

Expression and characterization of a DNase I-Fc fusion enzyme

Journal of Biological Chemistry, ISSN: 00219258

Dwyer; Arthur Huang; Clark Q. Pan; Lazarus

April 1, 1999

Transcellular uptake mechanisms of the intestinal epithelial barrier - Part one

Pharmaceutical Science and Technology Today, ISSN: 14615347

Daugherty; Mrsny

April 1, 1999

Inhibitory effects of combinations of HER-2/neu antibody and chemotherapeutic agents used for treatment of human breast cancers

Oncogene, ISSN: 09509232

Pegram; Sheree Hsu; Gail D. Lewis; Pietras; Malgorzata Beryt; Mark X. Sliwkowski; Daniel Coombs; Deborah L. Baly; Fairooz F. Kabbinavar; Dennis J. Slamon

April 1, 1999

Apoptosis control by death and decoy receptors

Current Opinion in Cell Biology, ISSN: 09550674

Avi Ashkenazi; Vishva M. Dixit

March 26, 1999

Peroxisome proliferator-activated receptor γ ligands are potent inhibitors of angiogenesis in vitro and in vivo

Journal of Biological Chemistry, ISSN: 00219258

Xiaohua Xin; Suya Yang; Joe Kowalski; Mary E. Gerritsen

March 26, 1999

Binding specificities and affinities of egf domains for ErbB receptors

FEBS Letters, ISSN: 00145793

Jennifer T. Jones; Robert W. Akita; Mark X. Sliwkowski

March 26, 1999

Caspase-9 can be activated without proteolytic processing

Journal of Biological Chemistry, ISSN: 00219258

Henning R. Stennicke; Quinn L. Deveraux; Eric W. Humke; John C. Reed; Vishva M. Dixit; Guy S. Salvesen

March 19, 1999

Biochemical purification of a mammalian slit protein as a positive regulator of sensory axon elongation and branching

Cell, ISSN: 00928674

Hong Wang Kuan; Katja Brose; David Arnott; Thomas Kidd; Corey S. Goodman; William J. Henzel; Marc Tessier-Lavigne

March 19, 1999

Slit proteins bind robo receptors and have an evolutionarily conserved role in repulsive axon guidance

Cell, ISSN: 00928674

Katja Brose; Kimberly S. Bland; Hong Wang Kuan; David Arnott; William J. Henzel; Corey S. Goodman; Marc Tessier-Lavigne; Thomas Kidd

March 16, 1999

Insulin-like growth factor 1 is required for G2 progression in the estradiol-induced mitotic cycle

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Adesanya; Jian Zhou; Samathanam; Powell-Braxton; Carolyn Bondy

March 15, 1999

Immunocytochemical and morphological evidence for intracellular self- repair as an important contributor to mammalian hair cell recovery

Journal of Neuroscience, ISSN: 02706474

Zheng; Gilbert-Andre Keller; Gao

March 9, 1999

Autophosphorylation dependent destabilization of the insulin receptor kinase domain: Tryptophan-1175 reports changes in the catalytic cleft

Biochemistry, ISSN: 00062960

Steven M. Bishop; J. B. Alexander Ross; Ronald A. Kohanski

March 8, 1999

Protein tyrosine phosphatase-PEST regulates focal adhesion disassembly, migration, and cytokinesis in fibroblasts

Journal of Cell Biology, ISSN: 00219525

Alexandre Angers-Loustau; Jean-François Côté; Alain Charest; Dowbenko; Spencer; Lasky; Michel L. Tremblay

March 1, 1999

ABRF-97 SEQ: Sequencing results of a low-level sample

Journal of Biomolecular Techniques, ISSN: 15240215 19434731

Kathryn Stone; Joseph Fernandez; Arie Admon; William J. Henzel; William Lane; Michael Rohde; Laurey Steinke

March 1, 1999

Targeting therapeutic molecules to cell organelles

American Chemical Society, Polymer Preprints, Division of Polymer Chemistry, ISSN: 00323934

Gilbert-Andre Keller

March 1, 1999

Platelet activation in patients after an acute coronary syndrome: Results from the TIMI-12 trial

Journal of the American College of Cardiology, ISSN: 07351097

Kenneth A. Ault; Christopher P. Cannon; Jane Mitchell; John McCahan; Russell P. Tracy; Novotny; Reimann; Eugene Braunwald

Join Our Team

The little things we do every day add up to big breakthroughs. Making a difference in the lives of millions starts when you make a change in yours.

Two Scientists Walk Into a Bar

Two Scientists Walk Into a Bar

Listen to our podcast, where researchers talk about their work answering the toughest questions in human biology.