Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 12301 - 12350 OF 15701 RESULTS

January 1, 1999

The optimal flow rate and column length for maximum production rate of protein A affinity chromatography

Bioprocess Engineering, ISSN: 0178515X

Fahrner; Harish V. Iyer; Gregory S. Blank

January 1, 1999

Preclinical pharmacokinetics, interspecies scaling, and tissue distribution of a humanized monoclonal antibody against vascular endothelial growth factor

Journal of Pharmacology and Experimental Therapeutics, ISSN: 00223565

Yvonne S. Lin; Cindy B. Nguyen; Jose-Luis Mendoza; Escandon; David T.W. Fei; Meng; Modi

January 1, 1999

The yeast a1 and α2 homeodomain proteins do not contribute equally to heterodimeric DNA binding

Molecular and Cellular Biology, ISSN: 02707306

Yisheng Jin; Hualin Zhong; Andrew K. Vershon

January 1, 1999

A cardioactive peptide from the southern armyworm, Spodoptera eridania

Peptides, ISSN: 01969781

Kenji Furuya; Murray Hackett; Marc A. Cirelli; Kathleen M. Schegg; Houle Wang; Jeffrey Shabanowitz; Donald F. Hunt; David A. Schooley

January 1, 1999

Growth hormone binding affinity for its receptor surpasses the requirements for cellular activity

Biochemistry, ISSN: 00062960

Kenneth H. Pearce Jr.; Cunningham; Fuh; Tuula Teeri; James A. Wells

January 1, 1999

On the structural preservation of recombinant human growth hormone in a dried film of a synthetic biodegradable polymer

Journal of Pharmaceutical Sciences, ISSN: 00223549

Karen G. Carrasquillo; Henry R. Costantino; Rocio A. Cordero; Chung C. Hsu; Kai Griebenow

January 1, 1999

Determination of low-molecular-mass antioxidant concentrations in human respiratory tract lining fluids

American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN: 10400605

Albert Van Der Vliet; Charles A. O'Neill; Carroll E. Cross; John M. Koostra; William G. Volz; Barry Halliwell; Samuel Louie

January 1, 1999

Phage library-derived human anti-TETA and anti-DOTA scFv for pretargeting RIT

Hybridoma, ISSN: 0272457X

Sally J. DeNardo; Gerald L. DeNardo; Brush; Paul J. Carter

January 1, 1999

Evaluation of early computed tomographic findings in acute ischemic stroke

Stroke, ISSN: 00392499

Michael P. Marks; Holmgren; Allan J Fox; Suresh Patel; Rudiger Von Kummer; Froehlich

January 1, 1999

The GDNF protein family: Gene ablation studies reveal what they really do and how

Neuron, ISSN: 08966273

Rosenthal

January 1, 1999

Role of tumor necrosis factor and interferon gamma in endotoxin-induced E-selectin expression

Shock, ISSN: 10732322

Michael J. Eppihimer; Janice Russell; Robert R. Langley; Mary E. Gerritsen; D. Neil Granger

January 1, 1999

Biological actions of nerve growth factor in the peripheral nervous system

European Neurology, ISSN: 00143022

Cynthia A. Rask

January 1, 1999

Efficacy and concentration-response of murine anti-VEGF monoclonal antibody in tumor-bearing mice and extrapolation to humans

Toxicologic Pathology, ISSN: 01926233

Joyce Mordenti; Karen Thomsen; Vojtech Licko; Helen Chen; Meng; Napoleone Ferrara

January 1, 1999

Preclinical safety evaluation of rhuMAbVEGF, an antiangiogenic humanized monoclonal antibody

Toxicologic Pathology, ISSN: 01926233

Anne Ryan; Dorothy Bates Eppler; Kelly E. Hagler; Richard H. Bruner; Peter J. Thomford; Robert L. Hall; Shopp; Charles A. O'Neill

January 1, 1999

Decreased CGRP, but preserved Trk A immunoreactivity in nerve fibres in inflamed human superficial temporal arteries

Journal of Neurology, Neurosurgery and Psychiatry, ISSN: 00223050

Saldanha; Hongo; Plant; Acheson; Levy; Anand

January 1, 1999

Impact of microbiology practice on cumulative prevalence of respiratory tract bacteria in patients with cystic fibrosis

Journal of Clinical Microbiology, ISSN: 00951137

Michael R. Shreve; Butler; Kaplowitz; Harvey R. Rabin; Dennis C. Stokes; Michael Light; Warren E. Regelmann

January 1, 1999

Provision of medical information for drugs used in orphan and pediatric disorders

Drug Information Journal, ISSN: 00928615

David A. Graves

January 1, 1999

Intracellular fragments of the natriuretic peptide receptor-C (NPR-C) attenuate dopamine efflux

Endocrinology, ISSN: 00137227

Sujata Kanwal; David G Lowe; George J. Trachte

January 1, 1999

Thrombopoietic cytokines and reversal of thrombocytopenia after liver transplantation

European Journal of Gastroenterology and Hepatology, ISSN: 0954691X

Markus Peck-Radosavljevic; Johannes Zacherl; Martina Wichlas; Paul Sims; Meng; Simon Panzer; Emanuel Lipinski; Rudolf Steininger; Ferdinand Mühlbacher; Johann Pidlich; Alfred Gangl

January 1, 1999

Anti-inflammatory drugs and endothelial cell adhesion molecule expression in murine vascular beds

Gut, ISSN: 00175749

Mori; Horie; Mary E. Gerritsen; Anderson; D. Neil Granger

January 1, 1999

Protein inhalation powders: Spray drying vs spray freeze drying

Pharmaceutical Research, ISSN: 07248741

Maa; Phuong-Anh Nguyen; Sweeney; Steven J. Shire; Chung C. Hsu

January 1, 1999

Intracranial delivery of recombinant nerve growth factor: Release kinetics and protein distribution for three delivery systems

Pharmaceutical Research, ISSN: 07248741

W. Mark Saltzman; Michele W. Mak; Melissa J. Mahoney; Duenas; Cleland

January 1, 1999

Autotransplantation for Parkinson's disease goes a step further

Neuron, ISSN: 08966273

Choi-Lundberg; Rosenthal

January 1, 1999

Influence of calcium ions on the structure and stability of recombinant human deoxyribonuclease I in the aqueous and lyophilized states

Journal of Pharmaceutical Sciences, ISSN: 00223549

Bei Chen; Henry R. Costantino; Jun Liu; Chung C. Hsu; Steven J. Shire

January 1, 1999

Purification and characterization of a novel 35-kDa protein from transformed cardiomyocytes

Cell Biology International, ISSN: 10656995

Sundararaman Chandrasekhar; Pamela N. Münster; William A. Henzel

January 1, 1999

High-resolution mapping of discrete representational areas in rat somatosensory cortex using blood volume-dependent functional MRI

NeuroImage, ISSN: 10538119

James T. Palmer; De Crespigny; Simon P. Williams; Busch; Nicholas Van Bruggen

January 1, 1999

Induction of apoptosis in cancer cells by tumor necrosis factor and butyrolactone, an inhibitor of cyclin-dependent kinases

Brazilian Journal of Medical and Biological Research, ISSN: 0100879X

Belizário; Steve Sherwood; Beçak

January 1, 1999

Regulation of activin A in cell proliferation and hormone secretion by human normal trophoblast cells

Chinese Science Bulletin, ISSN: 10016538

Yanling Wang; Mathe; Woodroff; Shuyi Luo; Linzhi Zhuang

January 1, 1999

Gibbon ape leukemia virus receptor functions of type III phosphate transporters from CHOK1 cells are disrupted by two distinct mechanisms

Journal of Virology, ISSN: 0022538X

G. Jilani Chaudry; Karen B. Farrell; Yuan-Tsang Ting; Christian Schmitz; Yolanda S. Lie; Christos J. Petropoulos; Maribeth V. Eiden

January 1, 1999

Ca2+-dependent activity of human DNase I and its hyperactive variants

Protein Science, ISSN: 09618368

Clark Q. Pan; Lazarus

January 1, 1999

Pharmacokinetics of fosinopril and hydrochlorothiazide in healthy elderly and young men

Clinical Drug Investigation, ISSN: 11732563

David R. Much; Howard D. Uderman; Barbara Ameer; John Brennan; Bruce C. Stouffer; Daisy Whigan; Arthur DeVault; Donald VanHarken

January 1, 1999

Inactivating mutations and overexpression of BCL 10, a caspase recruitment domain-containing gene, in MALT lymphoma with t(1;14)(p22;q32)

Nature Genetics, ISSN: 10614036

Quangeng Zhang; Reiner Siebert; Minhong Yan; Bernd Hinzmann; Xiaoli Cui; Liquan Xue; Karen M. Rakestraw; Clayton W. Naeve; Georg Beckmann; Dennis D. Weisenburger; Warren G. Sanger; Hadwiga Nowotny; Michael Vesely; Evelyne Callet-Bauchu; Gilles Salles; Vishva M. Dixit; André Rosenthal; Brigitte Schlegelberger; Stephan W. Morris

January 1, 1999

Concanavalin A protects hair cells against gentamicin ototoxicity in rat cochlear explant cultures

Journal of Neurobiology, ISSN: 00223034

Zheng; Gao

January 1, 1999

Herceptin®: Breaking new ground

Cancer Biotherapy and Radiopharmaceuticals, ISSN: 10849785

Robert L. Cohen

January 1, 1999

Research technologies: Fulfilling the promise

FASEB Journal, ISSN: 08926638

Ruth H. Angeletti; Lynda F. Bonewald; Karen De Jongh; Ronald Niece; John Rush; Stults

January 1, 1999

Effects of recombinant human growth hormone on height and skeletal maturation in growth hormone-deficient children with and without severe pretreatment bone age delay

Hormone Research, ISSN: 03010163

J. Paul Frindik; Stephen F. Kemp; Judy P. Sy

January 1, 1999

Characterization of active-site aromatic residues in xylanase a from Streptomyces lividans

Protein Engineering, ISSN: 02692139

Roberge; François Shareck; Rolf Morosoli; Dieter Kluepfel; Claude Dupont

January 1, 1999

In vitro evaluation of microparticles and polymer gels for use as nasal platforms for protein delivery

Pharmaceutical Research, ISSN: 07248741

Claudia Witschi; Mrsny

January 1, 1999

The effect of formulation excipients on protein stability and aerosol performance of spray-dried powders of a recombinant humanized anti-IgE monoclonal antibody

Pharmaceutical Research, ISSN: 07248741

Andya; Maa; Henry R. Costantino; Phuong-Anh Nguyen; Nancy Dasovich; Sweeney; Chung C. Hsu; Steven J. Shire

January 1, 1999

Deficient T cell fate specification in mice with an induced inactivation of Notch1

Immunity, ISSN: 10747613

Freddy Radtke; Anne Wilson; Gerlinde Stark; Michele Bauer; Joost Van Meerwijk; H. Robson MacDonald; Michel Aguet

January 1, 1999

Effect of local anti-VEGF antibody treatment on tumor microvessel permeability

Microvascular Research, ISSN: 00262862

Hera C. Lichtenbeld; Napoleone Ferrara; Rakesh K. Jain; Lance L. Munn

January 1, 1999

IgE inhibition as a therapy for allergic disease

International Archives of Allergy and Immunology, ISSN: 10182438

Paula Jardieu; Robert B. Fick Jr.

January 1, 1999

Safety assessment of single-bolus administration of TNK tissue- plasminogen activator in acute myocardial infarction: The ASSENT-1 trial

American Heart Journal, ISSN: 00028703

Frans Van De Werf; Christopher P. Cannon; Anne Luyten; Katrijn Houbracken; Carolyn H. McCabe; Berioli; Bluhmki; Hans Sarelin; Wang-Clow; Fox; Eugene Braunwald

January 1, 1999

A comparison of the national registry of myocardial infarction 2 with the cooperative cardiovascular project

Journal of the American College of Cardiology, ISSN: 07351097

Nathan R. Every; Paul D. Frederick; Michael Robinson; Jonathan Sugarman; Laura J. Bowlby; Hal V. Barron

January 1, 1999

Hepatocyte growth factor inhibits amiloride-sensitive Na+ channel function in cystic fibrosis airway epithelium in vitro

Pulmonary Pharmacology and Therapeutics, ISSN: 10945539

Shen; Widdicombe; Mrsny

January 1, 1999

Transformation by v-Src: Ras-MAPK and PI3K-mTOR mediate parallel pathways

Molecular Biology of the Cell, ISSN: 10591524

Elicia M. Penuel; G. Steven Martin

January 1, 1999

The effect of growth hormone treatment on stature in Aarskog syndrome

Journal of Pediatric Endocrinology and Metabolism, ISSN: 0334018X

Anna Petryk; Samuel Richten; Judy P. Sy; Sandra L. Blethen

January 1, 1999

Depletion of eosinophils in mice through the use of antibodies specific for C-C chemokine receptor 3 (CCR3)

Journal of Leukocyte Biology, ISSN: 07415400

Grimaldi; Nai-Xuan Yu; Gabrielle Grunig; Brian W. P. Seymour; Françoise Cottrez; Douglas S. Robinson; Nancy Hosken; Walter G. Ferlin; Xiaoyan Wu; Hortensia Soto; Anne O'Garra; Maureen C. Howard; Coffman

January 1, 1999

Pharmacokinetics and pharmacodynamics of sibrafiban, an orally administered IIb/IIIa antagonist, in patients with acute coronary syndrome.

Journal of Clinical Pharmacology, ISSN: 00912700

Modi; Novotny; Reimann; Christopher P. Cannon; Braunwauld

January 1, 1999

Probing intermolecular backbone H-bonding in serine proteinase-protein inhibitor complexes

Chemistry and Biology, ISSN: 10745521

Wuyuan Lu; Michael Randal; Anthony A. Kossiakoff; Stephen B. H. Kent

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