Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 12901 - 12950 OF 15583 RESULTS

January 1, 1997

Disruption of a single allele of the nerve growth factor gene results in atrophy of basal forebrain cholinergic neurons and memory deficits

Journal of Neuroscience, ISSN: 02706474

Grace Chan; Merry Nishimura; Armanini; Crowley; Spencer; Phillips

January 1, 1997

Murine endothelial cells support fetal liver erythropoiesis and myelopoiesis via distinct interactions

British Journal of Haematology, ISSN: 00071048

Osamu Ohneda; Victoria L. Bautch

January 1, 1997

The crystal structure of vascular endothelial growth factor (VEGF) refined to 1.93 Å resolution: Multiple copy flexibility and receptor binding

Structure, ISSN: 09692126

Yves A. Muller; Hans W. Christinger; Keyt; De Vos

January 1, 1997

γ-heregulin: A novel heregulin isoform that is an autocrine growth factor for the human breast cancer cell line, MDA-MB-175

Oncogene, ISSN: 09509232

Gabriele Schaefer; V. Danial Fitzpatrick; Mark X. Sliwkowski

January 1, 1997

Receptors for the chemoattractants C5a and IL-8 are clustered on the surface of human neutrophils

Journal of Histochemistry and Cytochemistry, ISSN: 00221554

Gary D. Gray; Sharon R. Hasslen; Julia A. Ember; David F. Carney; Michael J. Herron; Stanley L. Erlandsen; Robert D. Nelson

January 1, 1997

Ischemic stroke injury is reduced in mice lacking a functional NADPH oxidase

Stroke, ISSN: 00392499

Walder; Green; Darbonne; Joanne Mathias; Julie Rae; Mary C. Dinauer; John T. Curnutte; G. Roger Thomas

January 1, 1997

Promiscuous use of CC and CXC chemokine receptors in cell-to-cell fusion mediated by a human immunodeficiency virus type 2 envelope protein

Journal of Virology, ISSN: 0022538X

Romke Bron; Klasse; David Wilkinson; Clapham; Annegret Pelchen-Matthews; Christine A. Power; Timothy N. C. Wells; Jin Kim; Stephen C. Peiper; James A. Hoxie; Mark Marsh

January 1, 1997

Antioxidants for prevention of methionine oxidation in recombinant monoclonal antibody HER2

Journal of Pharmaceutical Sciences, ISSN: 00223549

Lam; Yang; Cleland

January 1, 1997

Mucosal addressin cell adhesion molecule-1 (MAdCAM-1). Its binding motif for α4β7 and role in experimental colitis

Immunologic Research, ISSN: 0257277X

Sherman Fong; Susan Jones; Renz; Chiu; Anne Ryan; Presta; Jackson

January 1, 1997

Analysis of rat vestibular hair cell development and regeneration using calretinin as an early marker

Journal of Neuroscience, ISSN: 02706474

Zheng; Gao

January 1, 1997

Stimulating effect of both human recombinant inhibin A and activin A on immature porcine Leydig cell functions in vitro

Endocrinology, ISSN: 00137227

Hervé Lejeune; Franck Chuzel; Pascale Sanchez; Philippe Durand; Mather; José M. Saez

January 1, 1997

Normal platelets and megakaryocytes are produced in vivo in the absence of thrombopoietin

Blood, ISSN: 00064971

Bunting; Ramon Widmer; Michael T. Lipari; Linda Rangell; Hope Steinmetz; Karen Carver-Moore; Mark Moore; Gilbert-Andre Keller; Frederic J. De Sauvage

January 1, 1997

Physiological regulation of epithelial tight junctions is associated with myosin light-chain phosphorylation

American Journal of Physiology - Cell Physiology, ISSN: 03636143

Turner; Brian K. Rill; Susan L. Carlson; Denice K. Carnes; Rachel Kerner; Mrsny; James L. Madara

January 1, 1997

Process model and recipe structure, the conceptual design for a flexible batch plant

ISA Transactions, ISSN: 00190578

Hans Koning-Bastiaan

January 1, 1997

Csk and BatK Show Opposite Temporal Expression in the Rat CMS: Consistent with its Late Expression in Development, BatK Induces Differentiation of PC12 Cells

European Journal of Neuroscience, ISSN: 0953816X

Sophia S. Kuo

January 1, 1997

Specifications from a biotechnology industry perspective.

Developments in biological standardization, ISSN: 03015149

Robert L. Garnick

January 1, 1997

Preparation and Characterization of Poly(ethylene glycol)ylated Human Growth Hormone Antagonist

ACS Symposium Series, ISSN: 00976156

Olson; Richard L. Gehant; Mukku; Kathy L. O'Connell; Brandon Tomlinson; Klara Totpal; Winkler

January 1, 1997

O-015. rhIGF-I: Differential sensitivity to SQ bolus vs continuous delivery

Endocrinology and Metabolism, Supplement, ISSN: 1074939X

Nelly Mauras; Paul M. Martha Jr.; Quarmby; Haymond

January 1, 1997

The role of assay validation in specification development.

Developments in biological standardization, ISSN: 03015149

Baffi

January 1, 1997

MyD88: An adapter that recruits IRAK to the IL-1 receptor complex

Immunity, ISSN: 10747613

Holger Wesche; William J. Henzel; Wendy Shillinglaw; Shyun Li; Zhaodan Cao

January 1, 1997

Growth hormone/IGF-I and/or resistive exercise maintains myonuclear number in hindlimb unweighted muscles

Journal of Applied Physiology, ISSN: 87507587

Allen; Jon K. Linderman; Roy; Richard E. Grindeland; Mukku; Edgerton

January 1, 1997

The Pharmaceutical Development of Insulin: Historical Perspectives and Future Directions

ACS Symposium Series, ISSN: 00976156

Henry R. Costantino; Stanley Liauw; Samir Mitragotri; Langer; Klibanov; Victoria Sluzky

January 1, 1997

P-115. Recombinant human (rh) GHBP: Effects on GH action in the rat

Endocrinology and Metabolism, Supplement, ISSN: 1074939X

Deborah L. Mortensen; Carlsson; Winkler; Ross Clark

January 1, 1997

Hematologically important mutations: X-linked chronic granulomatous disease - An update

Blood Cells, Molecules, and Diseases, ISSN: 10799796

Heyworth; John T. Curnutte; Julie Rae; Noack; Andrew R. Cross

January 1, 1997

NGF binding to p75 enhances the sensitivity of sensory and sympathetic neurons to NGF at different stages of development

Molecular and Cellular Neuroscience, ISSN: 10447431

Antony Horton; Laramee; Sean Wyatt; Shih; Winslow; Alun M. Davies

January 1, 1997

Specification and Survival of Dopaminergic Neurons in the Mammalian Midbrain

Advances in Pharmacology, ISSN: 10543589

Rosenthal

January 1, 1997

Targeting technologies - The expanding patent literature

Journal of Drug Targeting, ISSN: 1061186X

Mrsny

January 1, 1997

Developing Pharmaceutical Protein Formulations: Assumptions and Analytical Tools

ACS Symposium Series, ISSN: 00976156

Shahrokh

January 1, 1997

Determining the water sorption monolayer of lyophilized pharmaceutical proteins

Journal of Pharmaceutical Sciences, ISSN: 00223549

Henry R. Costantino; Curley; Chung C. Hsu

January 1, 1997

Peripheral vascular stenosis in apolipoprotein e-deficient mice: Potential roles of lipid deposition, medial atrophy, and adventitial inflammation

Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN: 10795642

Hong Seog Seo; Donna M. Lombardi; Patti Polinsky; Powell-Braxton; Bunting; Schwartz; Michael E. Rosenfeld

January 1, 1997

A risk-benefit assessment of growth hormone use in children

Drug Safety, ISSN: 01145916

Sandra L. Blethen; Margaret H. Macgillivray

January 1, 1997

National Cooperative Growth Study substudy VI: The clinical utility of growth-hormone-binding protein, insulin-like growth factor I, and insulin- like growth factor-binding protein 3 measurements

Journal of Pediatrics, ISSN: 00223476

Kenneth M. Attie; Joanne R. Julius; Catherine Stoppani; Amy Chen Rundle

January 1, 1997

Pioneering recombinant growth hormone manufacturing: Pounds produced per mile of height

Journal of Pediatrics, ISSN: 00223476

Cronin

January 1, 1997

Partial growth-hormone insensitivity: The role of growth-hormone receptor mutations in idiopathic stature

Journal of Pediatrics, ISSN: 00223476

Goddard; Patrick Dowd; Chernausek; Geffner; Gertner; Hintz; Hopwood; Selna L. Kaplan; Plotnick; Alan D. Rogol; Rosenfield; Saenger; Nelly Mauras; Hershkopf; Angulo; Kenneth M. Attie

January 1, 1997

Consequences of growth hormone deficiency on cardiac structure, function, and β-adrenergic pathway: Studies in mutant dwarf rats

Endocrinology, ISSN: 00137227

Antonio Cittadini; Hinrik Strömer; Dorothy E. Vatner; Jessica D. Grossman; Sarah E. Katz; Ross Clark; James P. Morgan; Pamela Douglas

January 1, 1997

Vascular endothelial growth factor expression is higher in differentiated thyroid cancer than in normal or benign thyroid

Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X

Euy Y. Soh; Quan-Yang Duh; Saif A. Sobhi; Dave M. Young; Howard D. Epstein; Mariwil G. Wong; Y. Kit Garcia; Young D. Min; Richard F. Grossman; Allan E. Siperstein; Orlo H. Clark

January 1, 1997

Factors influencing the time to thrombolysis in acute myocardial infarction

Archives of Internal Medicine, ISSN: 00039926

Costas Lambrew; Laura J. Bowlby; William J. Rogers; Nisha C. Chandra; Douglas Weaver

December 21, 1996

Glycopinion: Biological significance and methods for the analysis of complex carbohydrates of recombinant glycoproteins

Biotechnology and Applied Biochemistry, ISSN: 08854513

T. Shantha Raju; Laura Lerner; O'Connor

December 21, 1996

Cardiotrophin-1 inhibits tumor necrosis factor production in the heart and serum of lipopolysaccharide-treated mice and in vitro in mouse blood cells

American Journal of Pathology, ISSN: 00029440

Fabio Benigni; Silvano Sacco; Diane Pennica; Pietro Ghezzi

December 17, 1996

The far upstream element-binding proteins comprise an ancient family of single-strand DNA-binding transactivators

Journal of Biological Chemistry, ISSN: 00219258

Terri Davis-Smyth; Robert C. Duncan; Tian Zheng; Gregory Michelotti; David Levens

December 17, 1996

Solution structure of the E-domain of Staphylococcal protein A

Biochemistry, ISSN: 00062960

Melissa A. Starovasnik; Nicholas J. Skelton; Mark P. O'Connell; Robert F. Kelley; Dorothea Reilly; Wayne J. Fairbrother

December 15, 1996

Neural cell type-specific expression of QKI proteins is altered in quakingviable mutant mice

Journal of Neuroscience, ISSN: 02706474

Rebecca J. Hardy; Carrie L. Loushin; Victor L. Friedrich Jr.; Qi Chen; Tom A. Ebersole; Robert A. Lazzarini; Karen Artzt

December 14, 1996

Crystallization of the receptor binding domain of vascular endothelial growth factor

Proteins: Structure, Function and Bioinformatics, ISSN: 08873585

Hans W. Christinger; Yves A. Muller; Lea Berleau; Keyt; Cunningham; Napoleone Ferrara; De Vos

December 13, 1996

Variable structures of Fis-DNA complexes determined by flanking DNA-protein contacts

Journal of Molecular Biology, ISSN: 00222836

Clark Q. Pan; Steven E. Finkel; Sarah E. Cramton; Jin-An Feng; David S. Sigman; Reid C. Johnson

December 10, 1996

Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by an anti-vascular endothelial growth factor/vascular permeability factor antibody

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Fan Yuan; Yi Chen; Marc Dellian; Nina Safabakhsh; Napoleone Ferrara; Rakesh K. Jain

December 1, 1996

Modulation of LFA-1 by an anti-cdlla antibody which distributes to lfa-1-expresslng cells in blood, spleen, liver, bone marrow, and kidney

FASEB Journal, ISSN: 08926638

Barbara Reitz; Washington; Hotaling; Wolfgang-feimball; Anne Ryan; Ramon Widmer; Betty Chan; Gilbert-Andre Keller; Kenneth D. Bauer; Paula Jardieu; Judy Fox

December 1, 1996

Structure-function studies of human interferon-a receptor II using mabs

FASEB Journal, ISSN: 08926638

Anan Chumharapai; Lu; Jin

December 1, 1996

Molecular recognition in protein complexes

FASEB Journal, ISSN: 08926638

James A. Wells; Brian C. Cunnmgham; Betty Li; Melissa A. Starovasnik; Wayne J. Fairbrother; Andrew Braisted

December 1, 1996

Basement membrane and repair of injury to peripheral nerve: Defining a potential role for macrophages, matrix metalloproteinases, and tissue inhibitor of metalloproteinases-1

Journal of Experimental Medicine, ISSN: 00221007

Monique La Fleur; Johnnie L. Underwood; Daniel A. Rappolee; Zena Werb

December 1, 1996

Induction of apoptosis by APO-2 ligand, a new member of the TNF cytokine family

FASEB Journal, ISSN: 08926638

Avi Ashkenazi; Pitti; Scot A. Marsters; Siegfried Ruppert; Christopher J. Donahue; Alison Moore

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