Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 12951 - 13000 OF 15583 RESULTS

Induction of autoimmune t cells and costimulatory ligands b7 and icam-1 by interferon-alpha
FASEB Journal, ISSN: 08926638
Debasis Chakrabarti; Hultgren; Timothy
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Are there more members of the CNTF-GPA family?
Perspectives on Developmental Neurobiology, ISSN: 10640517
David L. Shelton
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Identification of a GDP-L-fucose:polypeptide fucosyltransferase and enzymatic addition of O-linked fucose to EGF domains
Glycobiology, ISSN: 09596658
Yang Wang; Geoffrey F. Lee; Robert F. Kelley; Spellman
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Elevated blood pressure and enhanced myocardial contractility in mice with severe IGF-1 deficiency
Journal of Clinical Investigation, ISSN: 00219738
Giuseppe Lembo; Howard A. Rockman; John J. Hunter; Hope Steinmetz; Walter J. Koch; Lan Ma; Morton P. Prinz; John Ross Jr.; Kenneth R. Chien; Powell-Braxton
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Predominate neuronal localization of a soluble sialidase in Chinese hamster brain
FASEB Journal, ISSN: 08926638
Dybdal; Oline; Li; Li; Warner
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Development of neurotrophic factor therapy for Alzheimer's disease
CIBA Foundation Symposia, ISSN: 03005208
Franz Hefti; Armanini; Klaus D. Beck; Caras; Grace Chan; Godowski; Goodman; R. Glenn Hammonds; Melanie R Mark; Paul Moran; Merry Nishimura; Phillips; Shih; Janet Valverde; Winslow
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Factors affecting neuronal birth and death in the mammalian olfactory epithelium
CIBA Foundation Symposia, ISSN: 03005208
Anne L. Calof; J. David Holcomb; Jeffrey S. Mumm; Nobuko Hagiwara; Phu Tran; Kirk M. Smith; David L. Shelton
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Cross-desensitisation of neutrophil IL-8 receptors involves differential receptor subtype regulation
Thorax, ISSN: 00406376
Ian Sabroe; Hébert; Timothy J. Williams; Paul D. Collins
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Humanization of an Anti-Lymphocyte Function-Associated Antigen (LFA)-1 Monoclonal Antibody and Reengineering of the Humanized Antibody for Binding to Rhesus LFA-1
Journal of Immunology, ISSN: 00221767
Winifred Werther; Gonzalez; Shane J. O'Connor; McCabe; Betty Chan; Hotaling; Mark Champe; Judy Fox; Paula Jardieu; Berman; Presta
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Modulation of LFA-1 by an anti-cdlla antibody which distributes to lfa-1-expresslng cells in blood, spleen, liver, bone marrow, and kidney
FASEB Journal, ISSN: 08926638
Barbara Reitz; Washington; Hotaling; Wolfgang-feimball; Ryan; Ramon Widmer; Betty Chan; Gilbert-Andre Keller; Kenneth D. Bauer; Paula Jardieu; Judy Fox
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Functional effects of lymphotoxin on crushed peripheral nerve
Microsurgery, ISSN: 07381085
Javier Algora; Long-En Chen; Anthony V. Seaber; Grace H.W. Wong; James R. Urbaniak
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Analysis of mixture sequences derived from edman degradation data
Techniques in Protein Chemistry, ISSN: 10808914
William J. Henzel; Stults; Susan C. Wong; Angela K. Namenuk; James Yashio; Colin K. Watanabe
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Human hepatocyte growth factor in alcoholic liver disease: A comparison with change in α-fetoprotein
Alcoholism: Clinical and Experimental Research, ISSN: 01456008
Charles L. Mendenhall; Roos; Thomas E. Moritz; Gary A. Roselle; Antonio Chedid; Charles J. Grossman; Susan D. Rouster; Bennett; John R. Lake
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Fourier-transform infrared spectroscopy demonstrates that lyophilization alters the secondary structure of recombinant human growth hormone
Pharmaceutical Sciences, ISSN: 13566881
Henry R. Costantino; Tue H. Nguyen; Chung C. Hsu
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Multiple roles ofthrombopoietin (TPO) revealed by gene targeting
Experimental Hematology, ISSN: 0301472X
Frederic J. De Sauvage
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Prostaglandin F2α induces cardiac myocyte hypertrophy in vitro and cardiac growth in vivo
American Journal of Physiology - Heart and Circulatory Physiology, ISSN: 00029513
Lai; Hongkui Jin; Renhui Yang; Jane Winer; Wei; Randy Yen; King; Francis C. Zeigler; Ko Annie; Cheng; Bunting; Nicholas F. Paoni
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The application of tert-butylhydroperoxide oxidation to study sites of potential methionine oxidation in a recombinant antibody
Techniques in Protein Chemistry, ISSN: 10808914
Felicity J. Shen; Kwong; Rodney Keck; Reed J. Harris
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The regulation of angiogenesis by vascular endothelial growth factor
FORUM - Trends in Experimental and Clinical Medicine, ISSN: 11218142
Napoleone Ferrara
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Drug delivery issues in vaccine development
Pharmaceutical Research, ISSN: 07248741
Powell
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Controlled release technologies: Current status and future prospects
Pharmaceutical Research, ISSN: 07248741
Richard Guy; Powell; Joseph Fix; Kinam Park
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Fast capillary electrophoresis-laser induced fluorescence analysis of ligase chain reaction products: Human mitochondrial DNA point mutations causing Leber's hereditary optic neuropathy
Electrophoresis, ISSN: 01730835
Jochen Muth; Mickey Williams; Stephen J. Williams; Michael D. Brown; Douglas C. Wallace; Karger
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Antibody dependent cell-mediated cytotoxicity (adcc) of an anti-her2 antibody requires opsonization of tumor target
FASEB Journal, ISSN: 08926638
Allison; Hotalhig; Barbara Reitz; Debasish Tripathy; Judy Fox
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Characterization of the chinese hamster soluble sialidase gene
FASEB Journal, ISSN: 08926638
Ferrari; Managahas-Molony; Petropoulos; Warner
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Mouse RAD50 has limited epitopic homology to p53 and is expressed in the adult myocardium
Journal of Biological Chemistry, ISSN: 00219258
Kyung Keun Kim; Adil Daud; Susan C. Wong; Laura Pajak; Shih-Chong Tsai; He Wang; William J. Henzel; Loren J. Field
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Induction of vascular endothelial growth factor by insulin-like growth factor 1 in colorectal carcinoma
Journal of Biological Chemistry, ISSN: 00219258
Robert S. Warren; Hui Yuan; Mary R. Matli; Napoleone Ferrara; David B. Donner
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Glycerophosphorylethanolamine (GPEA) identified as an hepatocyte growth stimulator in liver extracts
Experimental Cell Research, ISSN: 00144827
Nelson; Moffat; Neil E. Jacobsen; William J. Henzel; Stults; King; Amy E. McMurtrey; Richard L. Vandlen; Steven A. Spencer
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A longitudinal assessment of hormonal and physical alterations during normal puberty in boys. III. The neuroendocrine growth hormone axis during late prepuberty
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X
Paul M. Martha Jr.; Alan D. Rogol; Johannes D. Veldhuis; Robert M. Blizzard
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Recombinant human inhibin-A administered early in the menstrual cycle alters concurrent pituitary and follicular, plus subsequent luteal, function in rhesus monkeys
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X
Theodore A. Molskness; Woodruff; David L. Hess; Dahl; Richard L. Stouffer
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Spray-coating of rhDNase on lactose: Effect of system design, operational parameters and protein formulation
International Journal of Pharmaceutics, ISSN: 03785173
Maa; Phuong-Anh Nguyen; Chung C. Hsu
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A negative regulatory region in the intracellular domain of the human interferon-α receptor
Journal of Biological Chemistry, ISSN: 00219258
Gibbs; Michelle Takahashi; Michel Aguet; Anan Chuntharapai
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Tumor necrosis factor receptors (Tnfr) in mouse fibroblasts deficient in Tnfr1 or Tnfr2 are signaling competent and activate the mitogen-activated protein kinase pathway with differential kinetics
Journal of Biological Chemistry, ISSN: 00219258
Alexandra Kalb; Horst Bluethmann; Mark Moore; Werner Lesslauer
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Confirmation by mass spectrometry of a trisulfide variant in methionyl human growth hormone biosynthesized in Escherichia coli
Analytical Chemistry, ISSN: 00032700
Eleanor Canova-Davis; Ida P. Baldonado; Chloupek; Victor Ling; Richard L. Gehant; Olson; Beth Gillece-Castro
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Short-term GDNF treatment provides long-term rescue of lesioned nigral dopaminergic neurons in a rat model of Parkinson's disease
Journal of Neuroscience, ISSN: 02706474
Christian Winkler; Hans Sauer; Lee; Anders Bjorklund
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The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog
Nature, ISSN: 00280836
Donna Stone; Mary Hynes; Armanini; Todd A. Swanson; Qimin Gu; Ronald L. Johnson; Matthew P. Scott; Diane Pennica; Goddard; Phillips; Markus Noll; Joan E. Hooper; Frederic J. De Sauvage; Rosenthal
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An evaluation of the accuracy of four ELISA methods for measuring natural and recombinant human interferon-g
Journal of Immunological Methods, ISSN: 00221759
Paasch; Baron R. Reed; Rodney Keck; Bryan Sandlund; Ellen Gilkerson; Shalaby
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Developmental abnormalities and age-related neurodegeneration in a mouse model of Down syndrome
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
David M. Holtzman; Daniela Santucci; Joshua Kilbridge; Jane Chua-Couzens; David J. Fontana; Scott E. Daniels; Johnson; Grace Chan; Yuling Sun; Elaine J. Carlson; Enrico Alleva; Charles J. Epstein; William C. Mobley
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Purification of insulin-like growth factor-I and related proteins using underivatized silica
Journal of Chromatography A, ISSN: 00219673
David H. Reifsnyder; Charles V. Olson; Etcheverry; Prashad; Stuart E. Builder
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Furilisin: A variant of subtilisin BPN' engineered for cleaving tribasic substrates
Biochemistry, ISSN: 00062960
Ballinger; Jeffrey Tom; James A. Wells
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Stable formulations of recombinant human growth hormone and interferon-γ for microencapsulation in biodegradable microspheres
Pharmaceutical Research, ISSN: 07248741
Cleland; Andrew J.S. Jones
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Design of biological equivalence programs for therapeutic biotechnology products in clinical development: A perspective
Pharmaceutical Research, ISSN: 07248741
Joyce Mordenti; Joy A. Cavagnaro; Green
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Involvement of interleukin (IL) 8 receptor in negative regulation of myeloid progenitor cells in vivo: Evidence from mice lacking the murine IL-8 receptor homologue
Journal of Experimental Medicine, ISSN: 00221007
Hal E. Broxmeyer; Scott Cooper; Cacalano; Hague; Edward Bailish; Mark Moore
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Molten globule intermediate of recombinant human growth hormone: Stabilization with surfactants
Biotechnology Progress, ISSN: 87567938
Narendra B. Bam; Cleland; Theodore W. Randolph
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When perfectly HLA-matched kidneys are refused for transplant: Implications for a national cooperative sharing system
Journal of the American College of Surgeons, ISSN: 10727515
Mary D. Ellison; Timothy J. Breen; Darcy B. Davies; Erick B. Edwards; Richard J. Mahoney; Otis P. Daily; Douglas J. Norman
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Tissue distribution and complex formation with IgE of an anti-IgE antibody after intravenous administration in cynomolgus monkeys
Journal of Pharmacology and Experimental Therapeutics, ISSN: 00223565
Judy Fox; Hotaling; Craig Struble; Jane Ruppel; Dorothy J. Bates; Schoenhoff
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L-Selectin Binds to P-Selectin Glycoprotein Ligand-1 on Leukocytes: Interactions between the Lectin, Epidermal Growth Factor, and Consensus Repeat Domains of the Selectins Determine Ligand Binding Specificity
Journal of Immunology, ISSN: 00221767
Lili Tu; Anjun Chen; Martha D. Delahunty; Kevin L. Moore; Susan R. Watson; Rodger P. McEver; Thomas F. Tedder
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Interleukin-8 (IL-8), melanoma growth-stimulatory activity, and neutrophil-activating peptide selectively mediate priming of the neutrophil NADPH oxidase through the type A or type B IL-8 receptor
Journal of Biological Chemistry, ISSN: 00219258
Green; Anan Chuntharapai; John T. Curnutte
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On-line simultaneous monitoring of ammonia and glutamine in a hollow-fiber reactor using flow injection analysis
Journal of Biotechnology, ISSN: 01681656
Stoll; Ruffieux; Schneider; Von Stockar; Ian W. Marison
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The renaturable 69- and 63-kDa protein kinases that undergo rapid activation in chemoattractant-stimulated guinea pig neutrophils are p21- activated kinases
Journal of Biological Chemistry, ISSN: 00219258
Jiabing Ding; Ulla G. Knaus; Jian P. Lian; Bokoch; John A. Badwey
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Regulation of WT1 by phosphorylation: Inhibition of DNA binding, alteration of transcriptional activity and cellular translocation
EMBO Journal, ISSN: 02614189
Ying Ye; Baisakhi Raychaudhuri; Austin L. Gurney; Christine E. Campbell; Bryan R. G. Williams
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Defective B Cell Development in Snell Dwarf (dw/dw) Mice Can Be Corrected by Thyroxine Treatment
Journal of Immunology, ISSN: 00221767
Encarnacion Montecino-Rodriguez; Ross Clark; Anne Johnson; Linda Collins; Kenneth Dorshkind
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