Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 13051 - 13100 OF 16048 RESULTS

January 1, 1998

Amino acid sequence similarity of Hev b 3 to two previously reported 27- and 23-kDa latex proteins allergenic to spina bifida patients

Allergy: European Journal of Allergy and Clinical Immunology, ISSN: 01054538

Yeang; Ward; Zamri; Dennis; Light

January 1, 1998

Activating Smoothened mutations in sporadic basal-cell carcinoma

Nature, ISSN: 00280836

Jingwu Xie; Maximilien Murone; Shiuh-Ming Luoh; Anne Ryan; Qimin Gu; Chaohui Zhang; Jeannette M. Bonifas; Ching-Wan Lam; Mary Hynes; Goddard; Rosenthal; Ervin H. Epstein Jr.; Frederic J. De Sauvage

January 1, 1998

Fourier-transform infrared spectroscopic investigation of the secondary structure of aqueous and dried recombinant human deoxyribonuclease I

Pharmacy and Pharmacology Communications, ISSN: 14608081

Henry R. Costantino; Bei Chen; Kai Griebenow; Chung C. Hsu; Steven J. Shire

January 1, 1998

Distinct expression patterns of notch family receptors and ligands during development of the mammalian inner ear

Mechanisms of Development, ISSN: 09254773

Lewis; Gretchen D. Frantz; David Carpenter; Frederic J. De Sauvage; Gao

January 1, 1998

AtDB, the Arabidopsis thaliana Database, and graphical-web-display of progress by the Arabidopsis genome initiative

Nucleic Acids Research, ISSN: 03051048

David J. Flanders; Shuai Weng; Fabien X. Petel; J. Michael Cherry

January 1, 1998

Mucoadhesive microparticles for antigen delivery

Proceedings of the Controlled Release Society, ISSN: 10220178

Claudia Witschi; Mrsny

January 1, 1998

Mucosal administration of a non-toxic Pseudomonas exotoxin-gp120 V3 loop chimera elevates gp120 specific IgG and IgA in the serum and saliva of BALB/c mice

Proceedings of the Controlled Release Society, ISSN: 10220178

Daugherty; Silva; Charlotte M. Fryling; David FitzGerald; Mrsny

January 1, 1998

Substantially attenuated hemodynamic responses to Escherichia coli- derived vascular endothelial growth factor given by intravenous infusion compared with bolus injection

Journal of Pharmacology and Experimental Therapeutics, ISSN: 00223565

Renhui Yang; Bunting; Annie Ko; Keyt; Modi; Zioncheck; Napoleone Ferrara; Hongkui Jin

January 1, 1998

Computer system validation: Value added activities meeting regulatory imperatives

Drug Information Journal, ISSN: 00928615

Woodrum

January 1, 1998

Effects of cardiotrophin-1 on haemodynamics and cardiac function in conscious rats

Cytokine, ISSN: 10434666

Hongkui Jin; Renhui Yang; Ko Annie; Diane Pennica; William I. Wood; Nicholas F. Paoni

January 1, 1998

Lymphocyte granule-mediated apoptosis: Matters of viral mimicry and deadly proteases

Immunology Today, ISSN: 01675699

Christopher J. Froelich; Vishva M. Dixit; Xiaohe Yang

January 1, 1998

Solvent evaporation processes for the production of controlled release biodegradable microsphere formulations for therapeutics and vaccines

Biotechnology Progress, ISSN: 87567938

Cleland

January 1, 1998

Nab1, a corepressor of NGFI-A (Egr-1), contains an active transcriptional repression domain

Molecular and Cellular Biology, ISSN: 02707306

Alex H. Swirnoff; Elizabeth D. Apel; John Svaren; Bradley R. Sevetson; Drazen B. Zimonjic; Nicholas C. Popescu; Jeffrey Milbrandt

January 1, 1998

Calcium-phosphate mediated DNA transfer into HEK-293 cells in suspension: Control of physicochemical parameters allows transfection in stirred media: Transfection and protein expression in mammalian cells

Cytotechnology, ISSN: 09209069

Martin Jordan; Christiane Köhne; Florian M. Wurm

January 1, 1998

Integrins α(v)β3 and α5β1 mediate attachment of lyme disease spirochetes to human cells

Infection and Immunity, ISSN: 00199567

Jenifer Coburn; Loranne Magoun; Bodary; John M. Leong

January 1, 1998

Chromatography in biotechnology: A user's perspective

LC-GC Europe, ISSN: 14716577

John Frenz

January 1, 1998

Stabilization of nerve growth factor during microencapsulation and release from microspheres

Proceedings of the Controlled Release Society, ISSN: 10220178

Lam; Duenas; Cleland

January 1, 1998

Requirement for Brn-3c in maturation and survival, but not in fate determination of inner ear hair cells

Development (Cambridge), ISSN: 09501991

Mengqing Xiang; Gao; Tama Hasson; Joyce J. Shin

January 1, 1998

Development of stable formulations for PLGA/PLA microsphere vaccines

Research in Immunology, ISSN: 09232494

Cleland

January 1, 1998

Pharmacokinetics, pharmacodynamics and tolerability of a potent, non-peptidic, GP IIb/IIIa receptor antagonist following multiple oral administrations of a prodrug form

Thrombosis and Haemostasis, ISSN: 03406245

Refino; Modi; Sherron L. Bullens; Cheryl Pater; Michael T. Lipari; Kirk D. Robarge; Brent Blackburn; Beresini; Thomas Weller; Beat Steiner; Bunting

January 1, 1998

Local delivery of vascular endothelial growth factor via PLGA depots for treatment of vascular disease

Proceedings of the Controlled Release Society, ISSN: 10220178

Ann Park; Duenas; Thomas W. Patapoff; Cleland

January 1, 1998

A data model for clinical study status reports

Drug Information Journal, ISSN: 00928615

David H. Christiansen; Sundin

January 1, 1998

Genetic approaches to the detection of contaminants in Escherichia coli fermentations

Biotechnology Progress, ISSN: 87567938

James R. Swartz; Nancy McFarland

January 1, 1998

Increased physical activity and the growth hormone-IGF-I axis in adolescent males

American Journal of Physiology - Regulatory Integrative and Comparative Physiology, ISSN: 03636119

Alon Eliakim; Jo Anne Brasel; Subburaman Mohan; Wai Lee T. Wong; Dan M. Cooper

January 1, 1998

Fast Edman cycles with accelerated PTH analysis

Protein Journal, ISSN: 18758355 15723887

William J. Henzel; Jake Tropea; Kishiyama; Wendy Shillinglaw; David Dupont; Steve O'Neil

January 1, 1998

Distinct molecular phenotypes in murine cardiac muscle development, growth, and hypertrophy

Journal of Molecular and Cellular Cardiology, ISSN: 00222828

Schoenfeld; Vasser; Jhurani; Ng; John J. Hunter; John Ross Jr.; Kenneth R. Chien; David G Lowe

January 1, 1998

A role for FADD in T cell activation and development

Immunity, ISSN: 10747613

Craig M. Walsh; Ben G. Wen; Arul M. Chinnaiyan; Karen M. O'Rourke; Vishva M. Dixit; Stephen M. Hedrick

January 1, 1998

Development and validation of the migraine-specific quality of life questionnaire

Headache, ISSN: 00178748

Priti Jhingran; Jane T. Osterhaus; David W. Miller; Jeffrey T. Lee; Leonard Kirchdoerfer

December 19, 1997

Determination of Ro 48-3656 in rat plasma by reversed-phase high-performance liquid chromatography. Comparison of 1.5-μm nonporous silica to 3.5-μm porous silica analytical columns

Journal of Chromatography B: Biomedical Applications, ISSN: 15726495

Paasch; Yvonne S. Lin; Seth Porter; Modi; Timothy J. Barder

December 15, 1997

The effect of size, charge and cyclization of model peptides on their in vitro release from DL-PLGA microspheres

Journal of Controlled Release, ISSN: 01683659

Okumu; Cleland; Ronald T. Borchardt

December 15, 1997

Recombinant human growth hormone poly(lactic-co-glycolic acid) (PLGA) microspheres provide a long lasting effect

Journal of Controlled Release, ISSN: 01683659

Cleland; Duenas; Daugherty; Marian; Yang; Wilson; Abbie Celniker; Shahzamani; Quarmby; Chu; Mukku; Mac; Roussakis; Nancy Gillette; Brooks Boyd; Yeung; Brooks; Maa; Chung C. Hsu; Andrew J.S. Jones

December 12, 1997

Heregulins and the ErbB-2/3/4 receptors in gliomas

Journal of Neuro-Oncology, ISSN: 0167594X

Manfred Westphal; Leonie Meima; Szonyi; Julie A. Lofgren; Meissner; Wolfgang Hamel; Nikolics; Mark X. Sliwkowski

December 9, 1997

Inhibition of HIV type 1 infectivity by constrained α-helical peptides: Implications for the viral fusion mechanism

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

J. Kevin Judice; Jeffrey Tom; Wei Huang; Wrin; Vennari; Christos J. Petropoulos; Robert S. McDowell

December 9, 1997

A family of genes required for maintenance of cell wall integrity and for the stress response in Saccharomyces cerevisiae

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

James Verna; Adriana Lodder; Kyunghee Lee; Alicia Vagts; Roymarie Ballester

December 1, 1997

Therapeutic monoclonal as the treatment of allergic disease

Proceedings of the Western Pharmacology Society, ISSN: 00838969

Paula Jardieu

December 1, 1997

Engineered receptor cytoplasmic domains with fixed signal output: Probing mechanism with design

FASEB Journal, ISSN: 08926638

Andrea G Cochran

December 1, 1997

Hemodynamic effects of scatter factor in conscious rats

FASEB Journal, ISSN: 08926638

Hongkui Jin; Renhui Yang; Annie Ko; Ralph H. Schwall; Bunting

December 1, 1997

ErbB3 is required for normal cerebellar and cardiac development: A comparison with ErbB2- and heregulin-deficient mice

Development (Cambridge), ISSN: 09501991

Sharon Erickson; Sue O'Shea; Nazli Ghaboosi; Linda Loverro; Gretchen D. Frantz; Michele Bauer; Lucy Lu; Mark Moore

December 1, 1997

Potent biflnctional anticoagulants: kunitz domain - tissue factor fusion proteins

FASEB Journal, ISSN: 08926638

Geoffrey F. Lee

December 1, 1997

How integrins are activated

Nature, ISSN: 00280836

Lasky

December 1, 1997

Intravenous infusion of vascular endothelial growth factor (VEGF) substantially attenuates its hemodynamic effects

FASEB Journal, ISSN: 08926638

Renhui Yang; Bunting; Annie Ko; Keyt; Napoleone Ferrara; Hongkui Jin

December 1, 1997

Inhibition of angiogenesis by blocking vegf action: mutational analysis of vegf:receptor binding and epitope mapping of neutralizing antibodies

Fibrinolysis and Proteolysis, ISSN: 13690191

Keyt

December 1, 1997

Neutralizing antibodies against epidermal growth factor and ErbB-2/neu receptor tyrosine kinases down-regulate vascular endothelial growth factor production by tumor cells in vitro and in vivo: Angiogenic implications for signal transduction therapy of solid tumors

American Journal of Pathology, ISSN: 00029440

Alicia M. Viloria Petit; Janusz Rak; Mien-Chie Hung; Patricia Rockwell; Neil Goldstein; Brian M. Fendly; Robert S. Kerbel

December 1, 1997

Hemodynamic effects of scatter factor in conscious rats

Journal of Cardiovascular Pharmacology, ISSN: 01602446

Renhui Yang; Bunting; Annie Ko; Ralph H. Schwall; Hongkui Jin

December 1, 1997

RhDNase I is a well characterized protein

Pharmaceutical Sciences, ISSN: 13566881

Quan; Cacia; John Frenz; O'Connor

December 1, 1997

Engineering hyperactive human DNASE I with over 4000-fold higher activity in human serum

Protein Engineering, ISSN: 02692139

Pan; Tony H. Dodge; Baker; Sinicropi; Lazarus

December 1, 1997

Identification of components of the cell death pathway

Fibrinolysis and Proteolysis, ISSN: 13690191

Vishva M. Dixit

December 1, 1997

Native fluorescence detection of recombinant human growth hormone resolve from E. coli cell paste extract by capillary zone electrophoresls

FASEB Journal, ISSN: 08926638

McNerney; Robert L. Bridenbaugh

December 1, 1997

Metabolic labeling for monitoring sialylation of recombinant proteins in growing chinese hamster ovary cell cultures

FASEB Journal, ISSN: 08926638

Santeli; Ryll Twang; Jane Gunson; Warner

December 1, 1997

A novel receptor for Apo2L/TRAIL contains a truncated death domain

Current Biology, ISSN: 09609822

Scot A. Marsters; James P. Sheridan; Pitti; Arthur Huang; Skubatch; Daryl T. Baldwin; Jean Q. Yuan; Austin L. Gurney; Goddard; Godowski; Avi Ashkenazi

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