Genentech: Publications

January 1, 1996

Multicopy suppressors of prc mutant Escherichia coli include two HtrA (DegP) protease homologs (HhoAB), DksA, and a truncated rlpA

Journal of Bacteriology, ISSN: 00219193

Bass; Qimin Gu; Anthony Christen

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January 1, 1996

Flux measurements across Caco-2 monolayers may predict transport in human large intestinal tissue

Journal of Pharmaceutical Sciences, ISSN: 00223549

Rubas; Cromwell; Shahrokh; Villagran; Nguyen; Wellton; Tue H. Nguyen; Mrsny

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January 1, 1996

Penicillamine: An extractable chiral auxiliary providing excellent stereocontrol

Tetrahedron Asymmetry, ISSN: 09574166

Lutz S. Richter; Thomas Gadek

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January 1, 1996

Protection of MN-rgp120-immunized chimpanzees from heterologous infection with a primary isolate of human immunodeficiency virus type 1

Journal of Infectious Diseases, ISSN: 00221899

Berman; Murthy; Wrin; Vennari; Kathy Cobb; Eastman; Mark Champe; Nakamura; Donna Davison; Powell; Bussiere; Francis; Matthews; Timothy Gregory; John F. Obijeski

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January 1, 1996

Gene targeting in neuroscience: The systemic approach

Trends in Neurosciences, ISSN: 01662236

Gerlai

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January 1, 1996

Design and application of a low-temperature Peltier-cooling microscope stage

Journal of Pharmaceutical Sciences, ISSN: 00223549

Chung C. Hsu; Andrew J. Walsh; Hoc M. Nguyen; David E. Overcashier; Hans Koning-Bastiaan; Ralph C. Bailey; Steven L. Nail

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January 1, 1996

Vinblastine, a substrate for P-glycoprotein, flux across Caco-2 monolayers and rabbit jejunum

Proceedings of the Controlled Release Society, ISSN: 10220178

Mah; Rubas

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January 1, 1996

Baylisascaris procyonis larva migrans in a puppy: A case report and update for the veterinarian

Journal of the American Animal Hospital Association, ISSN: 05872871

Daniel G. Rudmann; Kevin R. Kazacos; Scott T. Storandt; Donna L. Harris; Evan B. Janovitz

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January 1, 1996

Development of recombinant human nerve growth factor (rhNGF) as a treatment for peripheral neuropathic disease

NeuroToxicology, ISSN: 0161813X

Rogers

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January 1, 1996

Full-length agrin isoform activities and binding site distributions on cultured Xenopus muscle cells

Molecular and Cellular Neuroscience, ISSN: 10447431

David F. Daggett; Donna Stone; H. Benjamin Peng; Nikolics

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January 1, 1996

Isomerization and formulation stability of the vaccine adjuvant QS-21

Journal of Pharmaceutical Sciences, ISSN: 00223549

Cleland; Kensil; Lim; Neil E. Jacobsen; Basa; Spellman; Deborah A. Wheeler; Jia-Yan Wu; Powell

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January 1, 1996

Evaluation of interleukin-1. Receptor antagonist (IL-1RA) and tumor necrosis factor binding protein (TNF-BP) in a rodent abscess model of host resistance

Immunopharmacology and Immunotoxicology, ISSN: 08923973

Colagiovanni; Shopp

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January 1, 1996

Characterization of upper respiratory disease in rats following neonatal inoculation with a rat-adapted influenza virus

Veterinary Pathology, ISSN: 03009858

Dye; Morgan; Neldon; Tepper; Burleson; Costa

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January 1, 1996

Caco-2 monolayers as a tool to examine intestinal uptake of particulates

Proceedings of the Controlled Release Society, ISSN: 10220178

Delie; Rubas

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January 1, 1996

Murine cardiotrophin-1 stimulates the acute-phase response in rat hepatocytes and H35 hepatoma cells

Journal of Interferon and Cytokine Research, ISSN: 10799907

Richards; Langdon; Diane Pennica; Gauldie

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January 1, 1996

Overview: Direct antithrombins and their therapeutic potential

Coronary Artery Disease, ISSN: 09546928

David Stump

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January 1, 1996

Identification of G-protein binding sites of the human interleukin-8 receptors by functional mapping of the intracellular loops

FASEB Journal, ISSN: 08926638

Bassam B. Damaj; Shaun R. McColl; Kuldeep Neote; Songqing; Kevin T. Ogborn; Hébert; Paul H. Naccache

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January 1, 1996

Substitution of serine or threonine at position 473 of tissue-type plasminogen activator increases its stability in plasma

Thrombosis and Haemostasis, ISSN: 03406245

Murtaza Alibhai; Alice M. Chow; Nicholas F. Paoni

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January 1, 1996

Extracellular matrix components and their receptors as targets for therapeutic intervention in inflammation and metastasis

Expert Opinion on Investigational Drugs, ISSN: 13543784

Pakianathan; Pemberton

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January 1, 1996

Protein engineering. Editorial overview

Current Opinion in Biotechnology, ISSN: 09581669

De Vos; Pluckthun

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January 1, 1996

Microencapsulation reactor scale-up by dimensional analysis

Journal of Microencapsulation, ISSN: 02652048

Maa; Chung C. Hsu

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January 1, 1996

Pharmacokinetics and interspecies scaling of recombinant human factor VIII

Toxicology and Applied Pharmacology, ISSN: 0041008X

Joyce Mordenti; Gary Osaka; Kit Garcia; Karen Thomsen; Vojtech Licko; Gloria Meng

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January 1, 1996

Inhibition of vascular endothelial growth factor prevents retinal ischemia-associated iris neovascularization in a nonhuman primate

Archives of Ophthalmology, ISSN: 00039950

Anthony P. Adamis; David T. Shima; Michael J. Tolentino; Evangelos S. Gragoudas; Napoleone Ferrara; Judah Folkman; Patricia A. D'Amore; Joan W. Miller

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January 1, 1996

Immunoadhesins: Principles and applications

Trends in Biotechnology, ISSN: 01677799

Steven M. Chamow; Avi Ashkenazi

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January 1, 1996

Carbohydrate metabolism in children receiving growth hormone for 5 years: Chronic renal insufficiency compared with growth hormone deficiency, Turner syndrome, and idiopathic short stature

Pediatric Nephrology, ISSN: 0931041X

Saenger; Kenneth M. Attie; Dimartino-Nardi; Richard N. Fine

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January 1, 1996

X-CGDbase: A database of X-CGD-causing mutations

Immunology Today, ISSN: 01675699

Dirk Roosl; John T. Curnutte; Johann Peter Hossle; Yu Lung Lau; Tadashi Ariga; Hiroyuki Nunoi; Mary C. Dinauer; Manfred Gahr; Anthony W. Segal; Peter E. Newburger; Mauro Giacca; Nicholas H. Keep; Rob Van Zwieten

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January 1, 1996

A novel tumor-derived mediator that sensitizes cytokine-resistant tumors to tumor necrosis factor

Journal of Surgical Research, ISSN: 00224804

Michael R. Marvin; Steven K. Libutti; Mark Kayton; Janet Kao; Joanne Hayward; Tracy Grikscheit; Yan-G. Fan; Jerold Brett; Weinberg; Roman Nowygrod; Paul Logerfo; Carl Feind; Kristen S. Hansen; Margaret A. Schwarz; David Stern; John Chabot

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January 1, 1996

Trophic factors and their role in the postischemic brain.

Advances in neurology, ISSN: 00913952

Nikolics; Franz Hefti; Thomas; Gluckman

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January 1, 1996

Effects of 12-week administration of dornase alfa in patients with advanced cystic fibrosis lung disease

Chest, ISSN: 00123692

Karen McCoy; Scott Hamilton; Charles A. Johnson

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January 1, 1996

Targeting technologies - Recent patent literature

Journal of Drug Targeting, ISSN: 1061186X

Mrsny

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January 1, 1996

Distribution of DNA and alginate in purulent cystic fibrosis sputum: Implications to pulmonary targeting strategies

Journal of Drug Targeting, ISSN: 1061186X

Mrsny; Daugherty; Sarah M. Short; Ramon Widmer; Mark Siegel; Gilbert-Andre Keller

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January 1, 1996

Randomised trial of MNrgp120 HIV-1 vaccine in symptomless HIV-1 infection

The Lancet, ISSN: 01406736

Joseph J. Eron Jr.; Ashby; Michael F. Giordano; Marlene Chernow; William M. Reiter; Steven G. Deeks; James P. Lavelle; Marcus Conant; Bienvenido G. Yangco; Perry G. Pate; Ramón A. Torres; Ronald T. Mitsuyasu; Tom Twaddell

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January 1, 1996

A karyotypic analysis of the lesser Malay chevrotain, Tragulus javanicus (Artiodactyla: Tragulidae)

Chromosome Research, ISSN: 09673849

Daniel S. Gallagher; Houck; Anne Ryan; Womack; Kumamoto

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January 1, 1996

Predictability of the clinical potency of NSAIDs from the preclinical pharmacodynamics in rats

Inflammation Research, ISSN: 10233830

Mukherjee; Victoria Hale; Borga; Stein

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January 1, 1996

Trophic factors and their role in the postischemic brain.

Advances in neurology, ISSN: 00913952

Nikolics; Franz Hefti; G. Roger Thomas; Gluckman

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January 1, 1996

Identification of Proteins from Two-Dimensional Electrophoresis Gels by Peptide Mass Fingerprinting

ACS Symposium Series, ISSN: 00976156

David Arnott; William J. Henzel; Stults

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January 1, 1996

Scintigraphic techniques for measuring in vivo deposition

Journal of Aerosol Medicine: Deposition, Clearance, and Effects in the Lung, ISSN: 08942684

Gonda

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January 1, 1996

Formation of a disulfide bond in an octreotide-like peptide: A multicenter study

Techniques in Protein Chemistry, ISSN: 10808914

Ruth H. Angeletti; Lisa Bibbs; Lynda F. Bonewald; Gregg B. Fields; John S. McMurray; William T. Moore; Stults

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January 1, 1996

MDIs: Physics of aerosol formation

Journal of Aerosol Medicine: Deposition, Clearance, and Effects in the Lung, ISSN: 08942684

Clark

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January 1, 1996

The Human Growth Hormone (hGH) Antagonist G120RhGH Does Not Antagonize GH in the Rat, But Has Paradoxical Agonist Activity, Probably Via the Prolactin Receptor

Endocrinology, ISSN: 00137227

Agneta Mode; Petra Tollet; Timothy Wells; Carmignac; Ross Clark; Wen Y. Chen; John J. Kopchick; Icaf Robinson

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January 1, 1996

Up and down the growth hormone cascade

Cytokine and Growth Factor Reviews, ISSN: 13596101

Ross Clark; Icaf Robinson

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January 1, 1996

Hepatocyte growth factor/scatter Factor: structure, function and regulation by glycosaminoglycans

Trends in Glycoscience and Glycotechnology, ISSN: 09157352

Richardson; Ralph H. Schwall; Zioncheck

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January 1, 1996

A compendium and hydropathy/flexibility analysis of common reactive sites in proteins: reactivity at Asn, Asp, Gln, and Met motifs in neutral pH solution.

Chinese Journal of Pharmaceutical Biotechnology, ISSN: 10780467

Amphlett; Cacia; Callahan; Cannova-Davis; Chang; Cleland; Darrington; DeYoung; Dhingra; Everett; Linda Foster; John Frenz; Garcia; Giltinan; Gitlin; Gombotz; Hageman; Reed J. Harris; Heller; Herman; Susan Hershenson; Hora; Ingram; Janes; Watanabe

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January 1, 1996

Stability characterization and formulation development of recombinant human deoxyribonuclease I [Pulmozyme, (dornase alpha)].

Chinese Journal of Pharmaceutical Biotechnology, ISSN: 10780467

Steven J. Shire

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January 1, 1996

In vivo biological effects of various forms of thrombopoietin in a murine model of transient pancytopenia

Stem Cells, ISSN: 10665099

G. Roger Thomas; Harold Thibodeaux; Carol J. Errett; Joanne Mathias; Marian; Meng; Richard L. Vandlen; Dan L. Eaton

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January 1, 1996

In vivo effects of cardiotrophin-1

Cytokine, ISSN: 10434666

Hongkui Jin; Renhui Yang; Gilbert-Andre Keller; Anne Ryan; Annie Ko; David Finkle; Todd A. Swanson; Wei Li; Diane Pennica; William I. Wood; Nicholas F. Paoni

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January 1, 1996

Hydroxyl and water molecule orientations in trypsin: comparison to molecular dynamic structures.

Basic life sciences, ISSN: 00905542

Robert S. McDowell; Anthony A. Kossiakoff

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January 1, 1996

Twelve-month evaluation of rhesus monkey dams and infants after relaxin (hRlx-2) infusion in late pregnancy

Reproductive Toxicology, ISSN: 08906238

Mari S. Golub; Norma J. Galiher; Peter K. Working; Adam Greenspan

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January 1, 1996

Nevirapine, zidovudine, and didanosine compared with zidovudine and didanosine in patients with HIV-1 infection a randomized, double-blind, placebo-controlled trial

Annals of Internal Medicine, ISSN: 00034819

Richard T. D'Aquila; Michael D. Hughes; Victoria A. Johnson; Margaret A. Fischl; Jean-Pierre Sommadossi; Song-Heng Liou; Joseph Timpone; Maureen Myers; Nesli Basgoz; Manette Niu; Martin S. Hirsch; Michael Saag; Jill Weingarten; John Gnann; Diane Havlir; Chris Fegan; Stephen Spector; Douglas D. Richman; Mark Jacobson; Kathy Dybeck; Patrick Joseph; Kathleen Clanon; Stacey McKenzie; Pam Daniel; Dale Dayton; Jill Leonard; Robert T. Schooley; Daniel Kuritzkes; Graham Ray; Beverly Putnam; Dushyantha Jayaweera; Janie Patrone-Reese; Thomas Tanner; Jo Moebus; Nancy Reed; Renee St Jacque; Keith Henry; Susan Swindells; Joe Eron; David Ragan; James Horton; Timothy Lane; Ian Frank; Anne Norris; Roger Pomerantz; Stephen Hauptman; Jan Geiseler; John Leedom; Frances Canchola; Connie Olson; Lawrence Deyton; Carla Pettinelli

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January 1, 1996

Development of a single-shot subunit vaccine for HIV-1. 3. Effect of adjuvant and immunization schedule on the duration of the humoral immune response to recombinant MN gp120

Journal of Pharmaceutical Sciences, ISSN: 00223549

Cleland; Barron; Daugherty; Eastman; Kensil; Lim; Weissburg; Wrin; Vennari; Powell

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