Genentech: Publications

January 1, 1993

Homotypic leukocyte aggregation triggered by a monoclonal antibody specific for a novel epitope expressed by the integrin β1 subunit: Conversion of nonresponsive cells by transfecting human integrin α4 subunit cDNA

Journal of Cellular Biochemistry, ISSN: 10974644 07302312

John L. Bednarczyk; James N. Wygant; Margit C. Szabo; Laura Molinari‐Storey; Renz; Fong; Bradley W. McIntyre

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January 1, 1993

Evidence supporting a role for cathepsin B in the generation of T cell antigenic epitopes of human growth hormone

Molecular Immunology, ISSN: 01615890

Gillian Bushell; Nelson; Chiu; Christopher Grimley; William J. Henzel; Burnier; Fong

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January 1, 1993

Receptor/ligand interactions in the C-C chemokine family

Advances in Experimental Medicine and Biology, ISSN: 00652598

Thomas J. Schall; John Mak; DiGregorio; Kuldeep Neote

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January 1, 1993

Production of Fusion Protein SpA:: EcoRI in Batch Culture in a 60‐L Airlift Tower Loop Reactor

Biotechnology Progress, ISSN: 15206033 87567938

Lutz Brandes; Xiaoan Wu; Hans E. Maschke; Heike Jürgens; Birgit Reinhardt; Karl Schügerl

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January 1, 1993

Glycoprotein IIb IIIa Antagonists

Annual Reports in Medicinal Chemistry, ISSN: 00657743

Brent Blackburn; Thomas Gadek

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January 1, 1993

Triply Convergent Synthesis of 15-(Phenoxymethyl) and 4,5-Allenyl Prostaglandins. Preparation of an Individual Isomer of Enprostil

Journal of Organic Chemistry, ISSN: 15206904 00223263

Owen W. Gooding; Colin C. Beard; Gary F. Cooper; Jackson

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January 1, 1993

Thermodynamic Analysis of an Antibody Functional Epitope

Biochemistry, ISSN: 15204995 00062960

Robert F. Kelley; Mark P. O'Connell

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January 1, 1993

Peptide Stability in Drug Development: In vitro Peptide Degradation in Plasma and Serum

Annual Reports in Medicinal Chemistry, ISSN: 00657743

Powell

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January 1, 1993

Identification and Structural Analysis of the Tetrasaccharide NeuAcα(2→6)Galβ(1→4)GlcNAcβ(1→3)Fucαl→O-Linked to Serine 61 of Human Factor IX

Biochemistry, ISSN: 15204995 00062960

Reed J. Harris; Basa; Victor Ling; Spellman; Van Halbeek; John Glushka; Kenneth J. Smith

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January 1, 1993

Neurotrophin-4/5 is a mammalian-specific survival factor for distinct populations of sensory neurons

Journal of Neuroscience, ISSN: 02706474

Alun M. Davies; Antony Horton; Louis E. Burton; Charles H. Schmelzer; Richard L. Vandlen; Rosenthal

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January 1, 1993

Overproduction of recombinant proteins by escherichia coli - employing the combinations of two and three different types of multicopy plasmids - in a 60-litre working volume airlift tower loop reactor

Process Biochemistry, ISSN: 13595113

Lutz Brandes; Xiaoan Wu; Hans E. Maschke; Karl Schügerl

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January 1, 1993

The Human Erythrocyte Inflammatory Peptide (Chemokine) Receptor. Biochemical Characterization, Solubilization, and Development of a Binding Assay for the Soluble Receptor

Biochemistry, ISSN: 15204995 00062960

Richard Horuk; Timothy J. Colby; Darbonne; Thomas J. Schall; Kuldeep Neote

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January 1, 1993

Vascular endothelial growth factor

Trends in Cardiovascular Medicine, ISSN: 10501738

Napoleone Ferrara

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January 1, 1993

Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo

Nature, ISSN: 00280836

K.Jin Kim; Bing Li; Jane Winer; Armanini; Nancy Gillett; Phillips; Napoleone Ferrara

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January 1, 1993

Difficulties in Precise Quantitation of CD4+T Lymphocytes for Clinical Trials: A Review

Biologicals, ISSN: 10958320 10451056

David T.W. Fei; Paxton; Chen

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January 1, 1993

5‐Hydroxytryptamine Receptors

Journal of Neurochemistry, ISSN: 14714159 00223042

Peroutka

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January 1, 1993

The molecular basis for growth hormone-receptor interactions

Recent Progress in Hormone Research, ISSN: 00799963

James A. Wells; Cunningham; Fuh; Henry B. Lowman; Bass; Michael G. Mulkerrin; Ultsch; Abraham M. Devos

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January 1, 1993

Epidermal growth factor stimulates vascular endothelial growth factor production by human malignant glioma cells: A model of glioblastoma multiforme pathophysiology

Molecular Biology of the Cell, ISSN: 10591524

Corey K. Goldman; Jin Kim; Wai Lee T. Wong; Vickie King; Tommy Brock; G. Yancey Gillespie

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January 1, 1993

Intravenous interleukin-8 inhibits granulocyte emigration from rabbit mesenteric venules without altering L-selectin expression or leukocyte rolling

Journal of Immunology, ISSN: 00221767

Klaus Ley; Baker; Myron I. Cybulsky; Gimbrone Jr.; Francis W. Luscinskas

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January 1, 1993

Cloning and expression of a human CDC42 GTPase-activating protein reveals a functional SH3-binding domain

Journal of Biological Chemistry, ISSN: 00219258

Elisabeth T. Barfod; Yi Zheng; Wun-Jing Kuang; Matthew J. Hart; Tony Evans; Richard A. Cerione; Avi Ashkenazi

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January 1, 1993

Engineering Fab' fragments for efficient F(ab)2 formation in Escherichia coli and for improved in vivo stability

Journal of Immunology, ISSN: 00221767

Maria L. Rodrigues; Snedecor; Christina Y. Chen; Wai Lee T. Wong; Shaily Garg; Gregory S. Blank; Daniel A. Maneval; Paul J. Carter

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January 1, 1993

Structural and functional aspects of RGD-containing protein antagonists of glycoprotein IIb-IIIa

Current Opinion in Biotechnology, ISSN: 09581669

Lazarus; Robert S. McDowell

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January 1, 1993

Synthetic chimeras of mouse growth factor‐associated glandular kallikreins. I. Kinetic properties

Protein Science, ISSN: 1469896X 09618368

Michael Blaber; Paul J. Isackson; Ralph A. Bradshaw; Burnier; James C. Marsters Jr.

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January 1, 1993

Solution Structure of Human Type-α Transforming Growth Factor Determined by Heteronuclear NMR Spectroscopy and Refined by Energy Minimization with Restraints

Biochemistry, ISSN: 15204995 00062960

Franklin J. Moy; Yu-Chin Li; Peter Rauenbuehler; Winkler; Harold A. Scheraga; Gaetano T Montelione

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January 1, 1993

Cysteine Pairing in the Glycoprotein IIbIIIa Antagonist Kistrin Using NMR, Chemical Analysis, and Structure Calculations

Biochemistry, ISSN: 15204995 00062960

Marc Adler; Paul J. Carter; Lazarus; Gerhard Wagner

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January 1, 1993

Mapping of the Binding Interfaces of the Proteins of the Bacterial Phosphotransferase System, HPr and IIAglc

Biochemistry, ISSN: 15204995 00062960

Yuan Chen; Peter E. Wright; Jonathan Reizer; Milton H. Saier Jr.; Wayne J. Fairbrother

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January 1, 1993

Assignment of 1H, 15N, and 13C Resonances, Identification of Elements of Secondary Structure and Determination of the Global Fold of the DNA-Binding Domain of GAL4

Biochemistry, ISSN: 15204995 00062960

Masahiro Shirakawa; Yasuharu Serikawa; Yoshimasa Kyogoku; Wayne J. Fairbrother; Peter E. Wright; Tadayasu Ohkubo

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January 1, 1993

Expression, purification, and characterization of recombinant ornatin e, a potent glycoprotein iib-iiia antagonist

Protein Expression and Purification, ISSN: 10465928

Paul Mazur; Dennis; Jana L. Seymour; Lazarus

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January 1, 1993

Crystallization and stoichiometry of binding of a complex between a rat intestinal Fc receptor and Fc

Journal of Molecular Biology, ISSN: 00222836

Andrew H. Huber; Robert F. Kelley; Louis N. Gastinel; Pamela J. Bjorkman

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January 1, 1993

Evidence that the growth hormone receptor mediates differentiation and development of the mammary gland

Endocrinology, ISSN: 19457170 00137227

Mark Feldman; Weifeng Ruan; Cunningham; James A. Wells; David Kleinberg

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January 1, 1993

Homotypic leukocyte aggregation triggered by a monoclonal antibody specific for a novel epitope expressed by the integrin β1 subunit: Conversion of nonresponsive cells by transfecting human integrin α4 subunit cDNA

Journal of Cellular Biochemistry, ISSN: 10974644 07302312

John L. Bednarczyk; James N. Wygant; Margit C. Szabo; Laura Molinari‐Storey; Renz; Sherman Fong; Bradley W. McIntyre

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January 1, 1993

Epstein-Barr virus-derived vectors for transient and stable expression of recombinant proteins

BioTechniques, ISSN: 07366205

Cachianes; Ho; Weber; Steven R. Williams; David V. Goeddel; Leung

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January 1, 1993

L- and E-selectin can recognize the same naturally occurring ligands on high endothelial venules

Journal of Immunology, ISSN: 00221767

Mebius; Susan R. Watson

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January 1, 1993

Substrate phage: Selection of protease substrates by monovalent phage display

Science, ISSN: 00368075

Matthews; James A. Wells

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January 1, 1993

Determination of type I receptor specificity by the type II receptors for TGF-β or activin

Science, ISSN: 00368075

Reinhard Ebner; Ruey-Hwa Chen; Sean Lawler; Zioncheck; Rik Derynck

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January 1, 1993

Optimizing binding and catalysis by phage display

Protein Engineering, Design and Selection, ISSN: 17410134 17410126

James A. Wells; Henry B. Lowman; Matthews

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January 1, 1993

Effects of tumor necrosis factor-α treatment on mortality in murine cytomegalovirus-infected mice

Antiviral Research, ISSN: 01663542

Anderson; Yolanda S. Lie; Mari-Anne L. Low; Fennie

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January 1, 1993

Bovine L-selectin: A peripheral lymphocyte homing receptor

Veterinary Immunology and Immunopathology, ISSN: 01652427

Bosworth; Dowbenko; Shuster; Harp

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January 1, 1993

Models of human endocrine disorders in transgenic rodents

Trends in Endocrinology and Metabolism, ISSN: 10432760

Stewart

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January 1, 1993

Genetic aspects of cancer

Advances in Human Genetics, ISSN: 0065275X

Goddard; Solomon

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January 1, 1993

Inactivation of the IGF‐I Gene in Mice Results in Perinatal Lethality

Annals of the New York Academy of Sciences, ISSN: 17496632 00778923

Powell-Braxton; Hollingshead; Giltinan; Sharon Pitts-Meek; Stewart

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January 1, 1993

Purification, receptor binding analysis, and biological characterization of human melanoma growth stimulating activity (MGSA). Evidence for a novel MGSA receptor

Journal of Biological Chemistry, ISSN: 00219258

Richard Horuk; Yansura; Dorothea Reilly; Steven A. Spencer; James H. Bourell; William J. Henzel; Glenn C. Rice; Elaine N. Unemori

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January 1, 1993

Production of monocyte chemotactic protein–1 in human type B synoviocytes. synergistic effect of tumor necrosis factor α and interferon‐γ

Arthritis and Rheumatism, ISSN: 15290131 00043591

Mohamed Hachicha; Palaniswami Rathanaswami; Thomas J. Schall; Shaun R. McColl

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January 1, 1993

Blocking monoclonal antibodies to αVβ3 integrin: A unique epitope of αVβ3 integrin is present on human osteoclasts

Experimental Cell Research, ISSN: 00144827

Anan Chuntharapai; Bodary; Horton; K.Jin Kim

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January 1, 1993

Molecular recognition in biological systems: From activation to inhibition

Biochemical Society Transactions, ISSN: 03005127

Anthony A. Kossiakoff; Thomas R. Hynes; De Vos

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January 1, 1993

Comparison of the Permeability Characteristics of a Human Colonic Epithelial (Caco-2) Cell Line to Colon of Rabbit, Monkey, and Dog Intestine and Human Drug Absorption

Pharmaceutical Research, ISSN: 1573904X 07248741

Rubas; Nancy Jezyk; George M. Grass

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January 1, 1993

The Relationship Between Powder Inhaler Resistance and Peak Inspiratory Conditions in Healthy Volunteers — Implications for In Vitro Testing

Journal of Aerosol Medicine: Deposition, Clearance, and Effects in the Lung, ISSN: 15579026 08942684

Clark; Hollingworth

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January 1, 1993

L-selectin-IgG chimera - In vitro and in vivo

Agents and Actions, ISSN: 00654299

Susan R. Watson

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January 1, 1993

Strain specificity and binding affinity requirements of neutralizing monoclonal antibodies to the C4 domain of gp120 from human immunodeficiency virus type 1

Journal of Virology, ISSN: 0022538X

Nakamura; Randal A. Byrn; Denise M. Wilkes; Judy Fox; Hobbs; Hastings; Wessling; Michael A. Norcross; Brian M. Fendly; Berman

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January 1, 1993

Crystal structure of the complex between human growth hormone and the extracellular domain of its reception

Biomedicine and Pharmacotherapy, ISSN: 07533322

De Vos

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