Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 14251 - 14300 OF 15701 RESULTS

February 1, 1992

Human Natriuretic Peptide Receptor-A Guanylyl Cyclase Is Self-Associated prior to Hormone Binding

Biochemistry, ISSN: 15204995 00062960

David G Lowe

February 1, 1992

The Type II Isoform of Bovine Brain Protein L-Isoaspartyl Methyltransferase Has an Endoplasmic Reticulum Retention Signal (…RDEL) at Its C-Terminus

Biochemistry, ISSN: 15204995 00062960

Steven M. Potter; Brett A. Johnson; Agnes Henschen; Aswad; Andrew W. Guzzetta

February 1, 1992

Characterization of a Recombinant Extracellular Domain of the Type 1 Tumor Necrosis Factor Receptor: Evidence for Tumor Necrosis Factor-α Induced Receptor Aggregation

Biochemistry, ISSN: 15204995 00062960

Diane Pennica; Paul E. Borchardt; Lewis; David V. Goeddel; William J. Kohr; Helga Raab; Brian M. Fendly; Steven J. Shire

February 1, 1992

Engagement of major histocompatibility complex class II molecules by superantigen induces inflammatory cytokine gene expression in human rheumatoid fibroblast-like synoviocytes

Journal of Experimental Medicine, ISSN: 15409538 00221007

Walid Mourad; Khalil Mehindate; Thomas J. Schall; Shaun R. McColl

February 1, 1992

A Region of Tissue Plasminogen Activator That Affects Plasminogen Activation Differentially with Various Fibrin(ogen)-Related Stimulators

Biochemistry, ISSN: 15204995 00062960

Eastman; Florian M. Wurm; Robert Van Reis; Deborah L. Higgins

January 31, 1992

A role for IGF-1 in the rescue of CNS neurons following hypoxic-ischemic injury

Biochemical and Biophysical Research Communications, ISSN: 10902104 0006291X

Peter Gluckman; Nicolin Klempt; Jian Guan; Carina Mallard; Ernest Sirimanne; Mike Dragunow; Martin Klempt; Singh; Chris Williams; Nikolics

January 1, 1992

Pharmacokinetic modeling for evaluating dosing strategies of anti-p185HER2 monoclonal antibodies

Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings, ISSN: 1557170X

Schoenhoff; Daniel A. Maneval; Hutchins; Gregory S. Blank; David Vetterlein; Joyce Mordenti; Green

January 1, 1992

Immunodominant structures of human growth hormone identified by homolog-scanning mutagenesis

Molecular Immunology, ISSN: 01615890

Joseph R. Weber; Nelson; Cunningham; James A. Wells; Fong

January 1, 1992

Human seminal relaxin is a product of the same gene as human luteal relaxin

Endocrinology, ISSN: 19457170 00137227

Winslow; Shih; James H. Bourell; Gerson Weiss; Baron R. Reed; Stults; Laura T. Goldsmith

January 1, 1992

Thyroid follicular cells produce interleukin-8

Journal of Clinical Endocrinology and Metabolism, ISSN: 19457197 0021972X

Weetman; Bennett; Wai Lee T. Wong

January 1, 1992

Passive immunoneutralization with a monoclonal antibody reveals a role for endogenous activin-b in mediating fsh hypersecretion during estrus and following ovariectomy of hypophysectomized, pituitary-grafted rats

Endocrinology, ISSN: 19457170 00137227

Louis V. DePaolo; Bald; Brian M. Fendly

January 1, 1992

Vascular endothelial growth factor messenger ribonucleic acid expression in the primate ovary

Endocrinology, ISSN: 19457170 00137227

Ravindranath; Lynda Little-Ihrig; Phillips; Napoleone Ferrara; Anthony J. Zeleznik

January 1, 1992

Recovery of Cholinergic Phenotype in the Injured Rat Neostriatum: Roles for Endogenous and Exogenous Nerve Growth Factor

Journal of Neurochemistry, ISSN: 14714159 00223042

C.Anthony Altar; Armanini; Dugich-Djordjevic; Bennett; Regina Williams; Shamiram Feinglass; Vincent R. Anicetti; Sinicropi; Bakhit

January 1, 1992

Activity and Biospecificity of Proteolyzed Forms and Dimeric Combinations of Recombinant Human and Murine Nerve Growth Factor

Journal of Neurochemistry, ISSN: 14714159 00223042

Louis E. Burton; Charles H. Schmelzer; Szonyi; Yedinak; Gorrell

January 1, 1992

High resolution removal of virus from protein solutions using a membrane of unique structure

Bio/Technology, ISSN: 0733222X

Anthony J. DiLeo; Anthony E. Allegrezza Jr.; Stuart E. Builder

January 1, 1992

DnaK-Mediated alterations in human growth hormone protein inclusion bodies

Bio/Technology, ISSN: 0733222X

Paul Blum; Mark Velligan; Lin; Abdul Matin

January 1, 1992

Polyethylene glycol enhanced protein refolding

Bio/Technology, ISSN: 0733222X

Cleland; Stuart E. Builder; James R. Swartz; Maijorie Winkler; Judy H. Chang; Daniel I. C. Wang

January 1, 1992

The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor

Science, ISSN: 00368075

Carlie De Vries; Escobedo; Hikaru Ueno; Houck; Napoleone Ferrara; Williams

January 1, 1992

Posttranslational modifications in the amino-terminal region of the large subunit of ribulose-1,5-bisphosphate carboxylase/oxygenase from several plant species

Plant Physiology, ISSN: 00320889

Robert L. Houtz; Loelle Poneleit; Samantha B. Jones; Malcolm Royer; Stults

January 1, 1992

Vascular endothelial growth factor induces interstitial collagenase expression in human endothelial cells

Journal of Cellular Physiology, ISSN: 10974652 00219541

Elaine N. Unemori; Napoleone Ferrara; Eugene A. Bauer; Edward P. Amento

January 1, 1992

Biochemical properties of the 75-kDa tumor necrosis factor receptor. Characterization of ligand binding, internalization, and receptor phosphorylation

Journal of Biological Chemistry, ISSN: 00219258

Diane Pennica; Lam; Mize; Weber; Lewis; Brian M. Fendly; Michael T. Lipari; David V. Goeddel

January 1, 1992

Chemical heterogeneity as a result of hydroxylamine cleavage of a fusion protein of human insulin-like growth factor I

Biochemical Journal, ISSN: 02646021

Eleanor Canova-Davis; Eng; Mukku; David H. Reifsnyder; Charles V. Olson; Victor Ling

January 1, 1992

Relaxin binding in the rat heart atrium

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Phyllis L. Osheroff; Cronin; Julie A. Lofgren

January 1, 1992

Virions of primary human immunodeficiency virus type 1 isolates resistant to soluble CD4 (sCD4) neutralization differ in sCD4 binding and glycoprotein gp120 retention from sCD4-sensitive isolates

Journal of Virology, ISSN: 0022538X

John P. Moore; Jane A. Mckeating; Yaoxing Huang; Avi Ashkenazi; David D. Ho

January 1, 1992

Utilization of homologous proteins to evaluate the safety of recombinant human proteins - case study: recombinant human interferon-gamma (rhIFN-γ)

Toxicology Letters, ISSN: 03784274

Green; Timothy G. Terrell

January 1, 1992

The apolipoprotein(a) moiety of lipoprotein(a) interacts with the complement activation fragment iC3b but does not functionally affect C3 activation or degradation

Atherosclerosis, ISSN: 00219150

Paul S. Seifert; Iris Roth; Zioncheck

January 1, 1992

Human natriuretic peptide receptor-A guanylyl cyclase. Hormone cross- linking and antibody reactivity distinguish receptor glycoforms

Journal of Biological Chemistry, ISSN: 00219258

David G Lowe; Brian M. Fendly

January 1, 1992

Pituitary follicular cells secrete an inhibitor of aortic endothelial cell growth: Identification as leukemia inhibitory factor

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Napoleone Ferrara; Jane Winer; William J. Henzel

January 1, 1992

Use of rapid serial sampling of creatine kinase MB for very early detection of myocardial infarction in patients with acute chest pain

American Heart Journal, ISSN: 10976744 00028703

Michael M. Marin; Sam L. Teichman

January 1, 1992

Immunodominant structures of human growth hormone identified by homolog-scanning mutagenesis

Molecular Immunology, ISSN: 01615890

Joseph R. Weber; Nelson; Cunningham; James A. Wells; Sherman Fong

January 1, 1992

Phase I study of continuous-infusion soluble CD4 as a single agent and in combination with oral dideoxyinosine therapy in children with symptomatic human immunodeficiency virus infection

Journal of Pediatrics, ISSN: 00223476

Robert N. Husson; Yoomie Chung; Joyce Mordenti; Karina M. Butler; Chen; A-M. Duliege; Pim Brouwers; Paul Jarosinski; Brigitta U. Mueller; Arthur J. Ammann; Philip A. Pizzo

January 1, 1992

Truncated and native insulinlike growth factor I enhance mucosal adaptation after jejunoileal resection

Gastroenterology, ISSN: 00165085

Jon A. Vanderhoof; Robert H. McCusker; Ross Clark; Hamid Mohammadpour; Darcy J. Blackwood; Richard F. Harty; Jung H.Y. Park

January 1, 1992

O-linked fucose is present in the first epidermal growth factor domain of factor XII but not protein C

Journal of Biological Chemistry, ISSN: 00219258

Reed J. Harris; Victor Ling; Spellman

January 1, 1992

The gene encoding human plasma carboxypeptidase B (CPB2) resides on chromosome 13

Genomics, ISSN: 10898646 08887543

Siao Ping Tsai; Drayna

January 1, 1992

The cytoplasmic domain of tissue factor is phosphorylated by a protein kinase C-dependent mechanism

Journal of Biological Chemistry, ISSN: 00219258

Zioncheck; Roy; Gordon A. Vehar

January 1, 1992

Paracrine Regulation of Reproductive Function by Inhibin and Activin

Proceedings of the Society for Experimental Biology and Medicine, ISSN: 15353699 00379727

Mather; Woodruff; Lynne Krummen

January 1, 1992

Molecular structural basis of ligand selectivity for 5-HT2 versus 5-HT1C cortical receptors

Naunyn-Schmiedeberg's Archives of Pharmacology, ISSN: 14321912 00281298

Pierce; Joanne Y. Kim; Peroutka

January 1, 1992

Structure-function analysis of hepatocyte growth factor: Identification of variants that lack mitogenic activity yet retain high affinity receptor binding

EMBO Journal, ISSN: 02614189

Lokker; Melanie R Mark; Luis; Bennett; Robbins; Baker; Godowski

January 1, 1992

Nucleotide sequence selection for increased expression of heterologous genes in Escherichia coli

Methods, ISSN: 10959130 10462023

Yansura; Laura C. Simmons

January 1, 1992

Strontium-90 induced bone tumours in beagle dogs: Effects of route of exposure and dose rate

International Journal of Radiation Biology, ISSN: 09553002

Nancy Gillett; Pool; Taylor; Muggenburg; Boecker

January 1, 1992

Integration and stability of CHO amplicons containing plasmid sequences

Developments in biological standardization, ISSN: 03015149

Florian M. Wurm; Maria G. Pallavicini; Arathoon

January 1, 1992

Human recombinant soluble decay accelerating factor inhibits complement activation in vitro and in vivo

Journal of Immunology, ISSN: 00221767

Paul Moran; Beasley; Gorrell; Martin; Gribling; Henry J. Fuchs; Nancy Gillett; Louis E. Burton; Caras

January 1, 1992

The synthesis of a phorbol 12,13-bis-lactone

Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X

Thomas E. Rawson; Timothy P. Kogan

January 1, 1992

Synthesis and biological activity of a 5,6-substituted teleocidin

Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X

Robert R. Webb II; Michael C. Venuti

January 1, 1992

Cloning, expression during development, and evidence for release of a trophic factor for ciliary ganglion neurons

Neuron, ISSN: 08966273

Leung; Annette S. Parent; Cachianes; Esch; James N. Coulombe; Nikolics; Felix P. Eckenstein; Rae Nishi

January 1, 1992

A simple method for the preparation of single-stranded polydeoxynucleotides of desired length

BioTechniques, ISSN: 07366205

White; Drossman; Drayna

January 1, 1992

Human growth hormone and extracellular domain of its receptor: Crystal structure of the complex

Science, ISSN: 00368075

De Vos; Ultsch; Anthony A. Kossiakoff

January 1, 1992

Conservation of the kinaselike regulatory domain is essential for activation of the natriuretic peptide receptor guanylyl cyclases

Molecular and Cellular Biology, ISSN: 02707306

Koller; Frederic J. De Sauvage; David G Lowe; David V. Goeddel

January 1, 1992

Pharmaceutics of protein drugs

Journal of Pharmacy and Pharmacology, ISSN: 00223573

Rodney Pearlman; Tue H. Nguyen

January 1, 1992

Comparison of second messenger formation in human keratinocytes following stimulation with epidermal growth factor and bradykinin

Second Messengers and Phosphoproteins, ISSN: 08957479

Johnson; King; Vera B. Morhenn

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