Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 14401 - 14450 OF 15701 RESULTS

January 1, 1992

Peptide mapping for detecting variants in protein products.

Developments in biological standardization, ISSN: 03015149

Robert L. Garnick

January 1, 1992

Involvement of zinc in binding of hGH to the prolactin receptor

Biomedicine and Pharmacotherapy, ISSN: 07533322

Wells

January 1, 1992

Crystal Structure of the Kringle 2 Domain of Tissue Plasminogen Activator at 2.4-Å. Resolution

Biochemistry, ISSN: 15204995 00062960

De Vos; Ultsch; Robert F. Kelley; Anthony A. Kossiakoff; Kaillathe Padmanabhan; Alexander Tulinsky; Mary L. Westbrook

January 1, 1992

Assignment of the Aliphatic 1H and 13C Resonances of the Bacillus Subtilis Glucose Permease IIA Domain Using Double- and Triple-Resonance Heteronuclear Three-Dimensional NMR Spectroscopy

Biochemistry, ISSN: 15204995 00062960

Mark Ranee; Peter E. Wright; Wayne J. Fairbrother; Arthur G. Palmer III; Jonathan Reizer; Milton H. Saier Jr.

January 1, 1992

Tetrapeptide inhibitors of protein farnesyltransferase: Ammo-terminal substitution in phenylalanine-containing tetrapeptides restores farnesylation

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Michael S. Brown; Joseph L. Goldstein; Kenneth J. Paris; Burnier; James C. Marsters Jr.

January 1, 1992

Antibody engineering

Current Opinion in Structural Biology, ISSN: 0959440X

Presta

January 1, 1992

Antibody engineering

Current Opinion in Biotechnology, ISSN: 09581669

Presta

January 1, 1992

Development of humanized bispecitic antibodies reactive with cytotoxic lymphocytes and tumor cells overexpressing the HER2 protooncogene

Journal of Experimental Medicine, ISSN: 15409538 00221007

Shalaby; Shepard; Presta; Maria L. Rodrigues; Peter C. L. Beverley; Marc Feldmann; Paul J. Carter

January 1, 1992

Characterization of the Saccharomyces Golgi complex through the cell cycle by immunoelectron microscopy

Molecular Biology of the Cell, ISSN: 10591524

Preuss; Jon Mulholland; Alex Franzusoff; Nava Segev; David Botstein

January 1, 1992

In vivo import of firefly luciferase into the glycosomes of Trypanosoma brucei and mutational analysis of the C-terminal targeting signal

Molecular Biology of the Cell, ISSN: 10591524

Sommer; Qi-Lin Cheng; Gilbert-Andre Keller; Ching C. Wang

January 1, 1992

In vitro ligand binding of125I-recombinant human activin a to the female rat brain

Endocrinology, ISSN: 19457170 00137227

Lyn B. Jakeman; Mather; Woodruff

January 1, 1992

Three-dimensional structure of an angiotensin II-fab complex at 3 Å: Hormone recognition by an anti-idiotypic antibody

Science, ISSN: 00368075

Garcia; Pierre M. Ronco; Pierre J. Verroust; Axel T. Brünger; Amzel

January 1, 1992

Monoclonal Antibodies to the Extracellular Domain of HIV-1IIIB gp160 that Neutralize Infectivity, Block Binding to CD4, and React with Diverse Isolates

AIDS Research and Human Retroviruses, ISSN: 19318405 08892229

Nakamura; Randal A. Byrn; Rosenthal; James P. Porter; Hobbs; Riddle; Eastman; Dowbenko; Timothy Gregory; Brian M. Fendly; Berman

January 1, 1992

Activin-A as an intraovarian modulator: Actions, localization, and regulation of the intact dimer in human ovarian cells

Journal of Clinical Investigation, ISSN: 00219738

Jaron Rabinovici; Susan J. Spencer; Nicola Doldi; Paul C. Goldsmith; Ralph H. Schwall; Robert B. Jaffe

January 1, 1992

Reduction of α-naphthylisothiocyanate-induced hepatotoxicity by recombinant human hepatocyte growth factor

Endocrinology, ISSN: 19457170 00137227

Roos; Timothy G. Terrell; Godowski; Steven M. Chamow; Ralph H. Schwall

January 1, 1992

X-ray crystal structures of transforming p21 ras mutants suggest a transition-state stabilization mechanism for GTP hydrolysis

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Gilbert G. Privé; Michael V. Milburn; Liang Tong; Abraham M. Devos; Ziro Yamaizumi; Nishimura; Sung-Hou Kim

January 1, 1992

Applications of Ultrafast HPLC to Process Development of Recombinant DNA‐Derived Proteins

Biotechnology Progress, ISSN: 15206033 87567938

Olson; Richard L. Gehant

January 1, 1992

Evidence of a role for mesothelial cell-derived interleukin 8 in the pathogenesis of asbestos-induced pleurisy in rabbits

Journal of Clinical Investigation, ISSN: 00219738

Alice M. Boylan; Ruegg; Kim; Hébert; John M. Hoeffel; Robert Pytela; Dean Sheppard; Ira M. Goldstein; V. Courtney Broaddus

January 1, 1992

Growth hormone augments superoxide anion secretion of human neutrophils by binding to the prolactin receptor

Journal of Clinical Investigation, ISSN: 00219738

Yung-Kang Fu; Sean Arkins; Germaine Fun; Cunningham; James A. Wells; Sherman Fong; Cronin; Robert Dantzer; Keith W. Kelley

January 1, 1992

Petrology, petrochemistry, and stromatolites of the Middle to Late Proterozoic Beck Spring Dolomite, eastern Mojave Desert, California

Canadian Journal of Earth Sciences, ISSN: 00084077

Marian; Osborne

January 1, 1992

Backbone Dynamics of the Bacillus subtilis Glucose Permease IIA Domain Determined from 15N NMR Relaxation Measurements

Biochemistry, ISSN: 15204995 00062960

Martin J. Stone; Peter E. Wright; Wayne J. Fairbrother; Arthur G. Palmer III; Jonathan Reizer; Milton H. Saier Jr.

January 1, 1992

Two TNF receptors

Immunology Today, ISSN: 01675699

Louis A. Tartaglia; David V. Goeddel

January 1, 1992

Peptide stability in drug development: A comparison of peptide reactivity in different biological media

Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549

Powell; Howard M. Grey; Federico C. A. Gaeta; Alessandro Sette; Colon

January 1, 1992

Multiple domains of the RNA polymerase I activator hUBF interact with the TATA-binding protein complex hSL1 to mediate transcription

Genes and Development, ISSN: 08909369

Hans-Michael Jantzen; Alice M. Chow; David S. King; Robert Tjian

January 1, 1992

Principles of the design and operational considerations of large scale high performance liquid chromatography (HPLC) systems for proteins and peptides purification.

Bioseparation, ISSN: 0923179X

Wisniewski

January 1, 1992

Antibody expression in bacteriophage systems: The future of monoclonal antibodies?

Current Opinion in Biotechnology, ISSN: 09581669

Lisa J. Garrard; Eugene A. Zhukovsky

January 1, 1992

Humanization of an anti-p185HER2 antibody for human cancer therapy

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Paul J. Carter; Presta; Cornelia M. Gorman; John B.B. Ridgway; Henner; Wai Lee T. Wong; Rowland; Claire Kotts; Monique E. Carver; Shepard

January 1, 1992

Recent studies on retrovirus-like particles in Chinese hamster ovary cells.

Developments in biological standardization, ISSN: 03015149

Dinowitz; Yolanda S. Lie; Mari-Anne L. Low; Lazar; Fautz; Beverly J. Potts; Sernatinger; Anderson

January 1, 1992

Glycosylation-dependent cell adhesion molecule 1: A novel mucin-like adhesion ligand for L-selectin

Cold Spring Harbor Symposia on Quantitative Biology, ISSN: 00917451

Lasky; Mark S. Singer; Dowbenko; Yasuyuki Imai; William J. Henzel; Christopher Fennie; Susan R. Watson; Steven D. Rosen

January 1, 1992

Antithrombotic effect of a monoclonal antibody against tissue factor in a rabbit model of platelet-mediated arterial thrombosis

Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN: 10795642

Ik-Kyung Jang; Herman K. Gold; Robert C. Leinbach; John T. Fallon; Desire Collen; Josiah N. Wilcox

January 1, 1992

Recognition of angiotensin II: Antibodies at different levels of an idiotypic network are superimposable

Science, ISSN: 00368075

Garcia; Desiderio; Pierre M. Ronco; Pierre J. Verroust; Amzel

January 1, 1992

Identification of proteins binding to interferon-inducible transcriptional enhancers in hematopoietic cells

Journal of Biological Chemistry, ISSN: 00219258

Wedrychowski; William J. Henzel; Laurel Huston; Paslidis; Debra Ellerson; Michele McRae; David Seong; O. M. Zack Howard; Albert Deisseroth

January 1, 1992

A GDP dissociation inhibitor that serves as a GTPase inhibitor for the Ras-like protein CDC42Hs

Science, ISSN: 00368075

Matthew J. Hart; Yoshiro Maru; David Leonard; Owen N. Witte; Tony Evans; Richard A. Cerione

January 1, 1992

Growth hormone augments superoxide anion secretion of human neutrophils by binding to the prolactin receptor

Journal of Clinical Investigation, ISSN: 00219738

Yung-Kang Fu; Sean Arkins; Germaine Fun; Cunningham; James A. Wells; Fong; Cronin; Robert Dantzer; Keith W. Kelley

December 20, 1991

Crystals of the complex between human growth hormone and the extracellular domain of its receptor

Journal of Molecular Biology, ISSN: 00222836

Ultsch; De Vos; Anthony A. Kossiakoff

December 1, 1991

p185(HER2) signal transduction in breast cancer cells

Journal of Biological Chemistry, ISSN: 00219258

Gary K. Scott; James M. Dodson; Pamela A. Montgomery; Johnson; Jay Sarup; Wai Lee T. Wong; Axel Ullrich; Shepard; Benz

December 1, 1991

Extracellular domain-IgG fusion proteins for three human natriuretic peptide receptors: Hormone pharmacology and application to solid phase screening of synthetic peptide antisera

Journal of Biological Chemistry, ISSN: 00219258

Brian D. Bennett; Bennett; Roderick V. Vitangcol; Jewett; Burnier; William J. Henzel; David G Lowe

December 1, 1991

Characterization of the Tryptic Map of Recombinant DNA Derived Tissue Plasminogen Activator by High-Performance Liquid Chromatography-Electrospray Ionization Mass Spectrometry

Analytical Chemistry, ISSN: 15206882 00032700

Victor Ling; Andrew W. Guzzetta; Eleanor Canova-Davis; Stults; William S. Hancock; Covey; Shushan

December 1, 1991

Growth hormone receptor and binding protein

Recent Progress in Hormone Research, ISSN: 00799963

Steven A. Spencer; Leung; Godowski; Glenn Hammonds; Michael J. Waters; William I. Wood

December 1, 1991

Structure of the lutropin/choriogonadotropin receptor

Recent Progress in Hormone Research, ISSN: 00799963

Deborah L. Segaloff; Rolf Sprengel; Nikolics; Mario Ascoli

December 1, 1991

Determining the optimum residual moisture in lyophilized protein pharmaceuticals

Developments in biological standardization, ISSN: 03015149

Chung C. Hsu; Carole A. Ward; Rodney Pearlman; Hoc M. Nguyen; Yeung; Curley

December 1, 1991

Generation of polyclonal antibodies against recombinant human acitvin a

Journal of Immunoassay, ISSN: 01971522

James A. Lofgren; Ralph H. Schwall; Charles H. Schmelzer; Wai Lee T. Wong

December 1, 1991

Cell transformation potential of a HER2 transmembrane domain deletion mutant retained in the endoplasmic reticulum

Journal of Biological Chemistry, ISSN: 00219258

Hudziak; Axel Ullrich

November 27, 1991

A nonfunctional sequence converted to a signal for glycophosphatidylinositol membrane anchor attachment

Journal of Cell Biology, ISSN: 00219525

Paul Moran; Caras

November 22, 1991

Scanning mutagenesis of interleukin-8 identifies a cluster of residues required for receptor binding

Journal of Biological Chemistry, ISSN: 00219258

Hébert; Roderick V. Vitangcol; Baker

November 11, 1991

A to G substitution identified in exon 2 of the G6PD gene among G6PD deficient chinese

Nucleic Acids Research, ISSN: 03051048

Lotung Chao; Chuan-su Du; Elaine Louie; Lin Zuo; Ellson Y. Chen; Bertram Lubin; Daniel T.Y. Chiu

November 8, 1991

Primary structure and functional expression of the human receptor for Escherichia coli heat-stable enterotoxin

Journal of Biological Chemistry, ISSN: 00219258

Frederic J. De Sauvage; Camerato; David V. Goeddel

November 5, 1991

The importance of a distal hydrogen bonding group in stabilizing the transition state in subtilisin BPN

Journal of Biological Chemistry, ISSN: 00219258

Braxton; James A. Wells

November 1, 1991

Selecting High-Affinity Binding Proteins by Monovalent Phage Display

Biochemistry, ISSN: 15204995 00062960

Henry B. Lowman; Bass; Simpson; James A. Wells

November 1, 1991

The vascular endothelial growth factor family of polypeptides

Journal of Cellular Biochemistry, ISSN: 10974644 07302312

Napoleone Ferrara; Houck; Lyn B. Jakeman; Jane Winer; Leung

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