Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 14601 - 14650 OF 15703 RESULTS

Engineering and design. Editorial overview
Current Opinion in Structural Biology, ISSN: 0959440X
F. Raymond Salemme; James A. Wells
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Industrial scale harvest of proteins from mammalian cell culture by tangential flow filtration
Biotechnology and Bioengineering, ISSN: 10970290 00063592
Robert Van Reis; Lee C. Leonard; Chung C. Hsu; Stuart E. Builder
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Primary structure and biological activity of human brain-derived neurotrophic factor
Endocrinology, ISSN: 19457170 00137227
Rosenthal; David V. Goeddel; Tue H. Nguyen; Evelyn Martin; Louis E. Burton; Shih; Laramee; Florian M. Wurm; Anthony J. Mason; Nikolics; Winslow
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Evolutionary conservation of a microbody targeting signal that targets proteins to peroxisomes, glyoxysomes, and glycosomes
Journal of Cell Biology, ISSN: 00219525
Gilbert-Andre Keller; Skaidrite Krisans; Stephen J. Gould; Sommer; Ching C. Wang; Schliebs; Kunau; Stuart Brody; Suresh Subramani
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In vivo induction of bone by recombinant human transforming growth factor β1
Journal of Bone and Mineral Research, ISSN: 15234681 08840431
L. Steven Beck; Arthur J. Ammann; Thomas B. Aufdemorte; Leo Deguzman; Yvette Xu; Wyne P. Lee; Lorrie L. Mcfatridge; Theresa L. Chen
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Thrombin and parathyroid hormone mobilize intracellular calcium in rat osteosarcoma cells by distinct pathways
Endocrinology, ISSN: 19457170 00137227
Michael Babich; Hester Choi; Johnson; King; Gay E. Alford; Robert A. Nissenson
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Cu,Zn superoxide dismutase is a peroxisomal enzyme in human fibroblasts and hepatoma cells
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Gilbert-Andre Keller; Warner; Steimer; Hallewell
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Structure and functional expression of a human interleukin-8 receptor
Science, ISSN: 00368075
William E. Holmes; James Lee; Wun-Jing Kuang; Glenn C. Rice; William I. Wood
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Thermodynamics of ligand binding and denaturation for his64 mutants of tissue plasminogen activator kringle‐2 domain
Proteins: Structure, Function and Bioinformatics, ISSN: 10970134 08873585
Robert F. Kelley; Abraham M. Devos; Scott Cleary
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Sequence and functional characterization of the human purine nucleoside phosphorylase promoter
Nucleic Acids Research, ISSN: 03051048
Joh J. Jonsson; Steven R. Williams; R.Scott McIvor
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The complement binding-like domains of the murine homing receptor facilitate lectin activity
Journal of Cell Biology, ISSN: 00219525
Susan R. Watson; Yasuyuki Imai; Christopher Fennie; Joyce Geoffrey; Mark S. Singer; Steven D. Rosen; Lasky
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Cloning and expression of a divergent integrin subunit β8
Journal of Biological Chemistry, ISSN: 00219258
Matthew Moyle; Napier; McLean
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Decreased metabolic clearance of endogenous growth hormone and specific alterations in the pulsatile mode of growth hormone secretion occur in prepubertal girls with turner’s syndrome
Journal of Clinical Endocrinology and Metabolism, ISSN: 19457197 0021972X
Johannes D. Veldhuis; Juan F. Sotos; Barry M. Sherman; Ann J. Johanson; Robert M. Blizzard; Barbara M. Lippe; Saenger
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Rapid publication TGF‐β1 induces bone closure of skull defects
Journal of Bone and Mineral Research, ISSN: 15234681 08840431
L. Steven Beck; Leo Deguzman; Wyne P. Lee; Yvette Xu; Lorrie L. Mcfatridge; Nancy Gillett; Edward P. Amento
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Identification of the human platelet GTPase activating protein for the CDC42Hs protein
Journal of Biological Chemistry, ISSN: 00219258
Matthew J. Hart; Katsuhiro Shinjo; Alan Hall; Tony Evans; Richard A. Cerione
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Selection, expression, and nucleotide sequencing of the glutamate dehydrogenase gene of Peptostreptococcus asaccharolyticus
Journal of Bacteriology, ISSN: 00219193
Snedecor; Chu; Ellson Y. Chen
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Dimerization of the extracellular domain of the human growth hormone receptor by a single hormone molecule
Science, ISSN: 00368075
Cunningham; Ultsch; De Vos; Michael G. Mulkerrin; Karl R. Clauser; James A. Wells
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The two different receptors for tumor necrosis factor mediate distinct cellular responses
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Louis A. Tartaglia; Weber; Figari; Reynolds; Michael A. Palladino; David V. Goeddel
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Catalysis of guanine nucleotide exchange on the CDC42Hs protein by the dbloncogene product
Nature, ISSN: 00280836
Matthew J. Hart; Alessandra Eva; Tony Evans; Stuart A. Aaronson; Richard A. Cerione
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Mutations in human interferon gamma affecting inclusion body formation identified by a general immunochemical screen
Nature Biotechnology, ISSN: 0733222X
Wetzel; Jeanne Perry; Connie A. Veilleux
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Inhibition of translation of transforming growth factor-β3 mRNA by its 5' untranslated region
Molecular and Cellular Biology, ISSN: 02707306
Arrick; Angela Lee; Richard L. Grendell; Rik Derynck
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Rational design of receptor-specific variants of human growth hormone
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Cunningham; James A. Wells
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Cytokines and growth factors positively and negatively regulate interstitial collagen gene expression in human vascular smooth muscle cells
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN: 10795642
Edward P. Amento; Niloofar Ehsani; Helen Palmer; Peter Libby
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Interleukin 1 protects from cytosine arabinoside-induced alopecia in the rat model
FASEB Journal, ISSN: 08926638
Joaquin J. Jimenez; Grace H.W. Wong; Adel A. Yunis
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Nerve growth factor and the neostriatum
Progress in Neuro-Psychopharmacology and Biological Psychiatry, ISSN: 02785846
C.Anthony Altar
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Red blood cells are a sink for interleukin 8, a leukocyte chemotaxin
Journal of Clinical Investigation, ISSN: 00219738
Darbonne; Glenn C. Rice; Margorie A. Mohler; Ted Apple; Hébert; Anthony J. Valente; Baker
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FAB assembly and enrichment in a monovalent phage display system
Bio/Technology, ISSN: 0733222X
Lisa J. Garrard; Yang; Mark P. O'Connell; Robert F. Kelley; Henner
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Resistance of primary isolates of human immunodeficiency virus type 1 to soluble CD4 is independent of CD4-rgp120 binding affinity
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Avi Ashkenazi; Smith; Scot A. Marsters; Riddle; Timothy Gregory; David D. Ho; Capon
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Defective endogenous retrovirus-like sequences and particles of Chinese hamster ovary cells.
Developments in biological standardization, ISSN: 03015149
Anderson; Yolanda S. Lie; Mari-Anne L. Low; Steven R. Williams; Florian M. Wurm; Dinowitz
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The Extracellular Domain of the Human Interferon Gamma Receptor Interacts with a Species-Specific Signal Transducer
Molecular and Cellular Biology, ISSN: 02707306
Gibbs; Steven R. Williams; Patrick W. Gray; Schreiber; Diane Pennica; Glenn C. Rice; David V. Goeddel
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Long-term inhibition of tumor growth by tumor necrosis factor in the absence of cachexia or T-cell immunity
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Teng; Ben H. Park; Koeppen; Kevin J. Tracey; Brian M. Fendly; Hans Schreiber
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Structure and function in recombinant HIV-1 gp120 and speculation about the disulfide bonding in the gp120 homologs of HIV-2 and SIV
Advances in Experimental Medicine and Biology, ISSN: 0065275X
Timothy Gregory; James A. Hoxie; Watanabe; Spellman
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Bone morphogenetic protein‐2b stimulation of growth and osteogenic phenotypes in rat osteoblast‐like cells: Comparison with TGF‐β1
Journal of Bone and Mineral Research, ISSN: 15234681 08840431
Theresa L. Chen; Rebecca L. Bates; Andrew Dudley; Glenn Hammonds Jr.; Edward P. Amento
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Cloning and sequencing of the cDNA encoding the rubber elongation factor of hevea brasiliensis
Plant Physiology, ISSN: 00320889
Elisabeth Goyvaerts; Dennis; Light; Nam-Hai Chua
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Fusion of sequence elements from non-anchored proteins to generate a fully functional signal for glycophosphatidylinositol membrane anchor attachment
Journal of Cell Biology, ISSN: 00219525
Paul Moran; Caras
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Functional expression of mammalian adenosine cyclic monophosphate-dependent protein kinase in saccharomyces cerevisiae
Methods in Enzymology, ISSN: 15577988 00766879
Zoller; Karen E. Johnson; Wes M. Yonemoto; Levin
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Interspecies Scaling of Clearance and Volume of Distribution Data for Five Therapeutic Proteins
Pharmaceutical Research, ISSN: 1573904X 07248741
Joyce Mordenti; Chen; Moore; Ferraiolo; Green
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Platelet-derived growth factor activity and mrna expression in healing vascular grafts in baboons association in vivo of platelet-derived growth factor mRNA and protein with cellular proliferation
Journal of Clinical Investigation, ISSN: 00219738
Michael A. Golden; Tina Au; Thomas R. Kirkman; Josiah N. Wilcox; Elaine W. Raines; Russell Ross; Alexander W. Clowes
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West Coast Parenteral Drug Association Genetic Stability Symposium 10-12 April 1991, San francisco, California
Biologicals, ISSN: 10958320 10451056
Robert L. Garnick
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Structure-activity relationship study of human interleukin-3: Role of the C-terminal region for biological activity
EMBO Journal, ISSN: 02614189
Lokker; Gerhard Zenke; Ulrike Strittmatter; Barbara Fagg; N. Rao Movva
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Monovalent phage display: A method for selecting variant proteins from random libraries
Methods, ISSN: 10959130 10462023
Henry B. Lowman; James A. Wells
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Organ specific cytokine therapy: Local activation of mononuclear phagocytes by delivery of an aerosol of recombinant interferon-γ to the human lung
Journal of Clinical Investigation, ISSN: 00219738
Ari Jaffe; Roland Buhl; Andrea Mastrangeli; Kenneth J. Holroyd; Saltini; Dorothy Czerski; Howard S. Jaffe; Susan M. Kramer; Stephen A. Sherwin; Crystal
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The vascular endothelial growth factor family: Identification of a fourth molecular species and characterization of alternative splicing of rna
Molecular Endocrinology, ISSN: 19449917 08888809
Houck; Napoleone Ferrara; Jane Winer; Cachianes; Bing Li; Leung
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Crystal structure of recombinant rabbit interferon-γ at 2.7-Å resolution
Journal of Biological Chemistry, ISSN: 00219258
Cleopas T. Samudzi; Louis E. Burton; Rubin
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Molecular genetics and drug discovery.
Molecular genetic medicine, ISSN: 10572805
Michael C. Venuti
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Ligand-mediated immunofunctional assay for quantitation of growth hormone-binding protein in human blood
Journal of Clinical Endocrinology and Metabolism, ISSN: 19457197 0021972X
Carlsson; Rowland; Ross Clark; Gesundheit; Wai Lee T. Wong
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Differential binding of transforming growth factor-β1, -β2, and -β3 by fibroblasts and epithelial cells measured by affinity cross-Linking of cell surface receptors
Molecular Endocrinology, ISSN: 19449917 08888809
Lyons; Duncan A. Miller; Graycar; Moses; Rik Derynck
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Mannosamine, a novel inhibitor of glycosyl-phosphatidylinositole incorporation into proteins
EMBO Journal, ISSN: 02614189
Michael P. Lisanti; Mark C. Field; Caras; Anant K. Menon; Rodriguez-Boulan
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Human nerve growth factor prevents degeneration of basal forebrain cholinergic neurons in primates
Annals of Neurology, ISSN: 15318249 03645134
Vassilis E. Koliatsos; Richard E. Clatterbuck; Haring J. W. Nauta; Beat Knüsel; Louis E. Burton; Franz Hefti; William C. Mobley; Donald L. Price
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Ornatins: potent glycoprotein IIb‐IIIa antagonists and platelet aggregation inhibitors from the leech Placobdella ornata
European Journal of Biochemistry, ISSN: 14321033 00142956
Paul Mazur; William J. Henzel; Jana L. Seymour; Lazarus
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