Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 15201 - 15250 OF 15703 RESULTS

July 24, 1987

Characterization of the antitumor activities of human tumor necrosis factor-α and the comparison with other cytokines: Induction of tumor-specific immunity

Journal of Immunology, ISSN: 00221767

Michael A. Palladino; Shalaby; Susan M. Kramer; Ferraiolo; Baughman; Deleo; Crase; Marafino Jr.; Aggarwal; Figari

June 11, 1987

Multiple RFLPs at the human cholesteryl ester transfer protein (CETP) locus

Nucleic Acids Research, ISSN: 03051048

Drayna; Lawn

May 26, 1987

Template-primer analogs as substrates for DNA polymerase

Nucleic Acids Research, ISSN: 03051048

Thomas R. Webb; Jhurani; Ng

May 11, 1987

The murine tumor necrosis factor-beta (lymphotoxin) gene sequence

Nucleic Acids Research, ISSN: 03051048

Patrick W. Gray; Ellson Y. Chen; Chang-Ben Li; Wei-Liang Tang; Nancy Ruddle

April 29, 1987

Designing substrate specificity by protein engineering of electrostatic interactions

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

James A. Wells; Powers; Bott; Graycar; David A. Estell

April 24, 1987

Compilation and comparison of the sequence context around the AUG startcodons in Saccharomyces cerevisiae mRNAs

Nucleic Acids Research, ISSN: 03051048

Robert W. Hamilton; Colin K. Watanabe; Herman A. de Boer

April 24, 1987

Primary structure of the human beta-adrenergic receptor gene

Nucleic Acids Research, ISSN: 03051048

Peter R. Schofield; Lucy M. Rhee; Ernest G. Peralta

April 14, 1987

Molecular cloning and amino acid sequence of rat enkephalinase

Biochemical and Biophysical Research Communications, ISSN: 10902104 0006291X

Bernard Malfroy; Peter R. Schofield; Wun-Jing Kuang; Peter H. Seeburg; Anthony J. Mason; William J. Henzel

April 10, 1987

Intron-exon structure of the human transforming growth factor-β precursor gene

Nucleic Acids Research, ISSN: 03051048

Rik Derynck; Lucy M. Rhee; Ellson Y. Chen; Ann van Tilburg

April 10, 1987

Sequence of the porcine transforming growth factor-beta precursor

Nucleic Acids Research, ISSN: 03051048

Rik Derynck; Lucy M. Rhee

March 13, 1987

GnRH-associated peptide (GAP) is cosecreted with GnRH into the hypophyseal portal blood of ovariectomized sheep

Biochemical and Biophysical Research Communications, ISSN: 10902104 0006291X

Clarke; Cummins; Karsch; Peter H. Seeburg; Nikolics

February 27, 1987

New substrates for enkephalinase (neutral endopeptidase) based on fluorescence energy transfer

Biochemical and Biophysical Research Communications, ISSN: 10902104 0006291X

Bernard Malfroy; Burnier

February 27, 1987

Regulation of mRNA accumulation by a human immunodeficiency virus trans-activator protein

Cell, ISSN: 00928674

Mark A. Muesing; Smith; Capon

February 13, 1987

Evidence that transforming growth factor-β is a hormonally regulated negative growth factor in human breast cancer cells

Cell, ISSN: 00928674

Cornelius Knabbe; Marc E. Lippman; Lalage M. Wakefield; Kathleen C. Flanders; Attan Kasid; Rik Derynck; Robert B. Dickson

February 13, 1987

Different transforming growth factor-α species are derived from a glycosylated and palmitoylated transmembrane precursor

Cell, ISSN: 00928674

Timothy S. Bringman; Patricia B. Lindquist; Rik Derynck

February 1, 1987

Synthesis of Messenger RNAs for Transforming Growth Factors α and β and the Epidermal Growth Factor Receptor by Human Tumors

Cancer Research, ISSN: 15387445 00085472

Rik Derynck; David V. Goeddel; Axel Ullrich; Timothy S. Bringman; Berger; Jordan U. Gutterman; Richard D. Williams

February 1, 1987

The role of cysteine oxidation in the thermal inactivation of t4 lysozyme

Protein Engineering, Design and Selection, ISSN: 17410126

Perry; Wetzel

January 26, 1987

Human, yeast and hybrid 3-phosphoglycerate kinase gene expression in yeast

Nucleic Acids Research, ISSN: 03051048

Christina Y. Chen; Ronald A. Hitzeman

January 26, 1987

Cleavage of single stranded oligonucleotides by EcoRI restriction endonuclease

Nucleic Acids Research, ISSN: 03051048

Norbert Bischofberger; Ng; Thomas R. Webb; Matteucci

January 16, 1987

Structure of the human and murine R-ras genes, novel genes closely related to ras proto-oncogenes

Cell, ISSN: 00928674

David G Lowe; Capon; Eric Delwart; Alan Y. Sakaguchi; Susan L. Naylor; David V. Goeddel

January 1, 1987

Distinct primary structures, ligand-binding properties and tissue-specific expression of four human muscarinic acetylcholine receptors.

EMBO Journal, ISSN: 02614189

Ernest G. Peralta; Avi Ashkenazi; Winslow; Smith; Ramachandran; Capon

January 1, 1987

Effect of phorbol esters on down-regulation and redistribution of cell surface receptors for tumor necrosis factor-alpha.

Journal of Biological Chemistry, ISSN: 00219258

Aggarwal; Eessalu

January 1, 1987

α2-antiplasmin enschede: Alanine insertion and abolition of plasmin inhibitory activity

Science, ISSN: 00368075

William E. Holmes; Lijnen; Nelles; Kluft; Nieuwenhuis; Rijken; Desire Collen

January 1, 1987

Corticotropin Receptors

Annals of the New York Academy of Sciences, ISSN: 17496632 00778923

Ramachandran; TSUBOKAWA; GOHIL

January 1, 1987

Characterization of Recombinant Human a2-Antiplasmin and of Mutants Obtained by Site-Directed Mutagenesis of the Reactive Site

Biochemistry, ISSN: 15204995 00062960

William E. Holmes; Lijnen; Desire Collen

January 1, 1987

Possible relationships between in vivo antitumour activity and toxicity of tumour necrosis factor-alpha.

CIBA Foundation Symposia, ISSN: 03005208

Michael A. Palladino; John R. Patton; Figari; Shalaby

January 1, 1987

Monoclonal antibodies to human tumor necrosis factors alpha and beta: application for affinity purification, immunoassays, and as structural probes

Hybridoma, ISSN: 0272457X

Timothy S. Bringman; Aggarwal

January 1, 1987

Growth hormone receptor and serum binding protein: Purification, cloning and expression

Nature, ISSN: 00280836

Leung; Steven A. Spencer; Cachianes; R. Glenn Hammonds; Collins; William J. Henzel; Ross Barnard; Michael J. Waters; William I. Wood

January 1, 1987

Primary structure and mRNA localization of protein F1, a growth-related protein kinase C substrate associated with synaptic plasticity.

EMBO Journal, ISSN: 02614189

Rosenthal; Chan; William J. Henzel; Haskell; Wun-Jing Kuang; Ellson Y. Chen; Josiah N. Wilcox; Axel Ullrich; David V. Goeddel; Routtenberg

January 1, 1987

Structural basis of muscarinic acetylcholine receptor subtype diversity

Trends in Pharmacological Sciences, ISSN: 0165604X

Ernest G. Peralta; Winslow; Avi Ashkenazi; Smith; Ramachandran; Capon

January 1, 1987

A repetitive sequence element 3′ of the human c‐Ha‐ras1 gene has enhancer activity

Journal of Cellular Physiology, ISSN: 10974652 00219541

Justus B. Cohen; Walter; Levinson

January 1, 1987

A parathyroid hormone-related protein implicated in malignant hypercalcemia: Cloning and expression

Science, ISSN: 00368075

Suva; Genine Winslow; Wettenhall; R. Glenn Hammonds; Moseley; Diefenbach-Jagger; Rodda; Kemp; Rodriguez; Ellson Y. Chen; Hudson; Martin; William I. Wood

January 1, 1987

Production of Recombinant Coagulation Proteins

Annals of the New York Academy of Sciences, ISSN: 17496632 00778923

Gordon A. Vehar

January 1, 1987

Interaction of One-Chain and Two-Chain Tissue Plasminogen Activator with Intact and Plasmin-Degraded Fibrin

Biochemistry, ISSN: 15204995 00062960

Deborah L. Higgins; Gordon A. Vehar

January 1, 1987

Macrophage-induced angiogenesis is mediated by tumour necrosis factor-α

Nature, ISSN: 00280836

S. Joseph Leibovich; Peter J. Polverini; Shepard; David M. Wiseman; Vera Shively; Nureddin Nuseir

January 1, 1987

Directing Ribosomes to a Single mRNA Species: A Method to Study Ribosomal Rna Mutations and Their Effects on Translation of a Single Messenger in Escherichia coli

Methods in Enzymology, ISSN: 15577988 00766879

Hui; Jhurani; Herman A. de Boer

January 1, 1987

Identification of human uromodulin as the tamm-horsfall urinary glycoprotein

Science, ISSN: 00368075

Diane Pennica; William J. Kohr; Wun-Jing Kuang; Debbie Glaister; Aggarwal; Ellson Y. Chen; David V. Goeddel

January 1, 1987

Gonadal Development and Gametogenesis in the Hypogonadal Mouse Are Restored by Gene Transfer

Annals of the New York Academy of Sciences, ISSN: 17496632 00778923

Anthony J. Mason; Pitts; Nikolics; Szonyi; Josiah N. Wilcox; Peter H. Seeburg; Stewart

January 1, 1987

Ovomucoid Third Domains from 100 Avian Species: Isolation, Sequences, and Hypervariability of Enzyme-Inhibitor Contact Residues

Biochemistry, ISSN: 15204995 00062960

Michael Laskowski Jr.; Ikunoshin Kato; Wojciech Ardelt; James Cook; Andrew Denton; Mark W. Emnie; William J. Kohr; Soon Jae Park; Kevin Parks; Barbara L. Schatzley; Oeyvind L. Schoenberger; Misao Tashiro; Gisela Vichot; Harry E. Whatley; Anna Wieczorek; Maciej Wieczorek

January 1, 1987

On the evolution of specificity and catalysis in subtilisin

Cold Spring Harbor Symposia on Quantitative Biology, ISSN: 00917451

James A. Wells; Cunningham; Graycar; David A. Estell; Paul J. Carter

January 1, 1987

Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene

Science, ISSN: 00368075

Dennis J. Slamon; Gary M. Clark; Steven Wong; Wendy J. Levin; Axel Ullrich; William L. McGuire

January 1, 1987

Regulation of neutrophil migration and superoxide production by recombinant tumor necrosis factors-α and -β: Comparison to recombinant interferon-γ and interleukin-1α

Blood, ISSN: 00064971

Figari; Mori; Michael A. Palladino

January 1, 1987

Blocking of HIV-1 infectivity by a soluble, secreted form of the CD4 antigen

Science, ISSN: 00368075

Smith; Randal A. Byrn; Scot A. Marsters; Timothy Gregory; Jerome E. Groopman; Capon

January 1, 1987

A national cooperative growth study on protropin

Acta Paediatrica Scandinavica, ISSN: 0001656X

Barry M. Sherman

January 1, 1987

Chicken Ovomucoid: Determination of Its Amino Acid Sequence, Determination of the Trypsin Reactive Site, and Preparation of All Three of Its Domains

Biochemistry, ISSN: 15204995 00062960

Ikunoshin Kato; James Schrode; William J. Kohr; Michael Laskowski Jr.

January 1, 1987

Development of partial tolerance to the gastrointestinal effects of high doses of recombinant tumor necrosis factor-α in rodents

Journal of Clinical Investigation, ISSN: 00219738

John R. Patton; Peters; McCabe; Crase; Hansen; Chen; Liggitt

January 1, 1987

Equilibrium and Kinetic Measurements of the Conformational Transition of Reduced Thioredoxin

Biochemistry, ISSN: 15204995 00062960

Robert F. Kelley; William Shalongc; Jagannadham; Earle Stellwagen

January 1, 1987

Alternative Splicing Increases the Diversity of the Human Protein Kinase C Family

DNA, ISSN: 15577430 01980238

Lisa Coussens; Lucy M. Rhee; Parker; Axel Ullrich

January 1, 1987

Industrial Scale Protein Purification: A Perspective

Bio/Technology, ISSN: 15206033 87567938

Nikos K. Harakas; Stuart E. Builder

January 1, 1987

Functional Role of Proteolytic Cleavage at Arginine-275 of Human Tissue Plasminogen Activator As Assessed by Site-Directed Mutagenesis

Biochemistry, ISSN: 15204995 00062960

Gordon A. Vehar; Keri M. Tate; Deborah L. Higgins; William E. Holmes; Winkler; Herbert Heyneker

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