Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 15251 - 15300 OF 15586 RESULTS

January 1, 1986

The oncogenic activation of human p21ras by a novel mechanism

Science, ISSN: 00368075

Walter; Clark; Levinson

January 1, 1986

Peripheral artery and bypass graft thrombolysis with recombinant human tissue-type plasminogen activator

Journal of Vascular Surgery, ISSN: 07415214

Robert A. Graor; Barbara Risius; Jess R. Young; Kevin Denny; Edwin G. Beven; Michael A. Geisinger; Norman R. Hertzer; Leonard P. Krajewski; Fred V. Lucas; Patrick J. O'Hara; William F. Ruschhaupt; Sheila Winton; Margaret G. Zelch; Grossbard

January 1, 1986

Isolation of the gene and hypothalamic cDNA for the common precursor of gonadotropin-releasing hormone and prolactin release-inhibiting factor in human and rat

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Adelman; Anthony J. Mason; Hayflick; Peter H. Seeburg

January 1, 1986

Identification of a missense mutation in the factor VIII gene of a mild hemophiliac

Science, ISSN: 00368075

Jane Gitschier; William I. Wood; Shuman; Lawn

January 1, 1986

The organization and nucleotide sequence of the Bacillus subtilis hisH, tyrA and aroE genes

Gene, ISSN: 03781119

Henner; Louise Band; Gail W. Flaggs; Ellson Y. Chen

January 1, 1986

Construction of a single-copy integration vector and its use in analysis of regulation of the trp operon of Bacillus subtilis

Gene, ISSN: 03781119

Shimotsu Hidenori; Henner

January 1, 1986

Novel form of transcription attenuation regulates expression of the Bacillus subtilis tryptophan operon

Journal of Bacteriology, ISSN: 00219193

Hidenori Shimotsu; Mitzi I. Kuroda; Yanofsky; Henner

January 1, 1986

A fortran implementation of univariate fourier series density estimation

Communications in Statistics: Simulation and Computation, ISSN: 15324141 03610918

Michael E. Tarter; William Freeman; Alan Hopkins

January 1, 1986

The cloning of factor VIII and the genetics of hemophilia A

Hospital Practice, ISSN: 87502836

Gordon A. Vehar; Lawn

January 1, 1986

Nerve growth factor mRNA in peripheral and central rat tissues and in the human central nervous system: Lesion effects in the rat brain and levels in Alzheimer's disease

Molecular Brain Research, ISSN: 0169328X

Goedert; Fine; Hunt; Axel Ullrich

January 1, 1986

Deoxynucleoside H-Phosphonate diester intermediates in the synthesis of internucleotide phosphate analogues

Tetrahedron Letters, ISSN: 00404039

Froehler

January 1, 1986

Saccharomyces cerevisiae secretes and correctly processes human interferon hybrid proteins containing yeast invertase signal peptides

Molecular and Cellular Biology, ISSN: 02707306

Chung N. Chang; Matteucci; Perry; Wulf; Christina Y. Chen; Ronald A. Hitzeman

January 1, 1986

Intracellular assembly and packaging of hepatitis B surface antigen particles occur in the endoplasmic reticulum

Journal of Virology, ISSN: 0022538X

Patzer; Nakamura; Simonsen; Levinson; Brands

January 1, 1986

Specificity of trna charging in tyr-trna synthetase

Protein Engineering, Design and Selection, ISSN: 17410134 17410126

Wetzel

January 1, 1986

What is protein engineering?

Protein Engineering, Design and Selection, ISSN: 17410134 17410126

Wetzel

January 1, 1986

A Sensitive Radioimmunoprecipitation Assay for the Detection of Antibody to Recombinant Human Gamma-Interferon: Comparison to a Bioassay Neutralization Test

Journal of Interferon Research, ISSN: 15577465 01978357

Chen; Vincent R. Anicetti; Toni Klassen; Berthold; Gaby Zahn; Wert Jr.; Geier; Andrew J.S. Jones

January 1, 1986

Regulation of pro-opiomelanocortin gene transcription in individual cell nuclei

Science, ISSN: 00368075

Robert T. Fremeau Jr.; James R. Lundblad; Dolan B. Pritchett; Josiah N. Wilcox; James L. Roberts

January 1, 1986

Regulation of the chelatin promoter during the expression of human serum albumin or yeast phosphoglycerate kinase in yeast

Bio/Technology, ISSN: 0733222X

Etcheverry; Forrester; Ronald A. Hitzeman

January 1, 1986

Immunopharmacology of tumor necrosis factors α and β

Trends in Pharmacological Sciences, ISSN: 01656147

Michael A. Palladino; Bryan S Finkle

January 1, 1986

Tumor necrosis factors: Gene structure and biological activities

Cold Spring Harbor Symposia on Quantitative Biology, ISSN: 00917451

David V. Goeddel; Aggarwal; Patrick W. Gray; Leung; Nedwin; Michael A. Palladino; John R. Patton; Diane Pennica; Shepard; Sugarman

January 1, 1986

Sequences 3' of the human c-Ha-ras1 gene positively regulate its expression and transformation potential.

Gene amplification and analysis, ISSN: 02752778

Colby; Justus B. Cohen; Yu; Levinson

January 1, 1986

Proteolytic Processing of Human Factor VIII. Correlation of Specific Cleavages by Thrombin, Factor Xa, and Activated Protein C with Activation And Inactivation of Factor VIII Coagulant Activity

Biochemistry, ISSN: 15204995 00062960

Dan L. Eaton; Rodriguez; Gordon A. Vehar

January 1, 1986

Transforming growth factor‐α: Structure and biological activities

Journal of Cellular Biochemistry, ISSN: 10974644 07302312

Rik Derynck

January 1, 1986

Cloned factor VIII and the molecular genetics of hemophilia

Cold Spring Harbor Symposia on Quantitative Biology, ISSN: 00917451

Lawn; William I. Wood; Jane Gitschier; Karen L. Wion; Eaton; Gordon A. Vehar; Tuddenham

January 1, 1986

Escherichia coli DnaK protein possesses a 5'-nucleotidase activity that is inhibited by appppA

Journal of Bacteriology, ISSN: 00219193

Bochner; Zylicz; Georgopoulos

January 1, 1986

Structural features of growth factor receptors with oncogenic potential

Biochemical Society Symposium, ISSN: 00678694

Ellson Y. Chen; Lisa Coussens; Yu-Cheng Liao

January 1, 1986

Unpaired Cysteine-54 Interferes with the Ability of an Engineered Disulfide To Stabilize T4 Lysozyme

Biochemistry, ISSN: 15204995 00062960

Perry; Wetzel

January 1, 1986

Purification and Characterization of Recombinant Single-Chain Urokinase Produced in Escherichia coli

Biochemistry, ISSN: 15204995 00062960

Winkler; Michael Blaber

January 1, 1986

D-Phe-Pro-Arg-chloromethylketone: Its potential use in inhibiting the formation of in vitro artifacts in blood collected during tissue-type plasminogen activator thrombolytic therapy

Thrombosis and Haemostasis, ISSN: 03406245

Mohler; Refino; Chen; Adair Hotchkiss

January 1, 1986

Human growth hormone: From clone to clinic

Cold Spring Harbor Symposia on Quantitative Biology, ISSN: 00917451

Peter H. Seeburg

January 1, 1986

Molecular basis of a human purine nucleoside phosphorylase deficiency

Cold Spring Harbor Symposia on Quantitative Biology, ISSN: 00917451

Steven R. Williams; R.Scott McIvor; Martin Jr.

January 1, 1986

Multiple, distinct forms of bovine and human protein kinase C suggest diversity in cellular signaling pathways

Science, ISSN: 00368075

Lisa Coussens; Parker; Lucy M. Rhee; Yang-Feng; Ellson Y. Chen; Waterfield; Uta Francke; Axel Ullrich

January 1, 1986

Equilibrium and Kinetic Measurements of the Conformational Transition of Thioredoxin in Urea

Biochemistry, ISSN: 15204995 00062960

Jane Wilson; William Shalongo; David Lowery; Earle Stellwagen; Robert F. Kelley

January 1, 1986

The hypogonadal mouse: Reproductive functions restored by gene therapy

Science, ISSN: 00368075

Anthony J. Mason; Pitts; Nikolics; Szonyi; Josiah N. Wilcox; Peter H. Seeburg; Stewart

January 1, 1986

A deletion truncating the gonadotropin-releasing hormone gene is responsible for hypogonadism in the hpg mouse

Science, ISSN: 00368075

Anthony J. Mason; Hayflick; Zoeller; Young III; Phillips; Nikolics; Peter H. Seeburg

January 1, 1986

The complete primary structure of protein kinase C - The major phorbol ester receptor

Science, ISSN: 00368075

Parker; Lisa Coussens; Nick Totty; Lucy M. Rhee; Susan Young; Ellson Y. Chen; Silvia Stabel; Waterfield; Axel Ullrich

January 1, 1986

Protein kinases in cellular signal transduction: Tyrosine kinase growth factor receptors and protein kinase C

Cold Spring Harbor Symposia on Quantitative Biology, ISSN: 00917451

Axel Ullrich; Riedel; Yarden; Lisa Coussens; Gray; Dull; Schlessinger; Waterfield; Parker

January 1, 1986

Characterization studies of human tissue-type plasminogen activator produced by recombinant DNA technology

Cold Spring Harbor Symposia on Quantitative Biology, ISSN: 00917451

Gordon A. Vehar; Spellman; Keyt; Ferguson; Rodney Keck; Chloupek; Reed J. Harris; William F. Bennett; Stuart E. Builder; William S. Hancock

January 1, 1986

Structure of the human insulin receptor precursor

Fernstrom Foundation Series, ISSN: 01677004

Axel Ullrich; Bell; Ellson Y. Chen

January 1, 1986

Sequence-Specific Cross-Linking of Deoxyoligonucleotides via Hybridization-Triggered Alkylation

Journal of the American Chemical Society, ISSN: 15205126 00027863

Thomas R. Webb; Matteucci

January 1, 1986

Endogeneous and heterologous expression of transforming growth factor-α in mammalian cells

Cold Spring Harbor Symposia on Quantitative Biology, ISSN: 00917451

Rik Derynck; Rosenthal; Patricia B. Lindquist

January 1, 1986

Transforming growth factor-α: A more potent angiogenic mediator than epidermal growth factor

Science, ISSN: 00368075

Alain B. Schreiber; Winkler; Rik Derynck

January 1, 1986

[60] Construction of Expression Vectors for Secretion of Human Interferons by Yeast

Methods in Enzymology, ISSN: 15577988 00766879

Ronald A. Hitzeman; Chung N. Chang; Matteucci; Jeanne Perry; William J. Kohr; Wulf; James R. Swartz; Christina Y. Chen; Arjun Singh

January 1, 1986

Cloning and expression of human lecithin-cholesterol acyltransferase cDNA

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

McLean; Fielding; Drayna; Dieplinger; Baer; William J. Kohr; William J. Henzel; Lawn

January 1, 1986

Neutralization of the AIDS retrovirus by antibodies to a recombinant envelope glycoprotein

Science, ISSN: 00368075

Lasky; Jerome E. Groopman; Christopher Fennie; Patricia M. Benz; Capon; Dowbenko; Nakamura; Nunes; Renz; Berman

December 17, 1985

Urea treatment allows dithiothreitol to release the binding subunit of the insulin receptor from the cell membrane: Implications for the structural organization of the insulin receptor

Biochemical and Biophysical Research Communications, ISSN: 10902104 0006291X

Grunfeld; Judy Kwan Shigenaga; Ramachandran

December 1, 1985

A prolactin-inhibiting factor within the precursor for human gonadotropin-releasing hormone

Nature, ISSN: 00280836

Nikolics; Anthony J. Mason; Éva Sznyi; Ramachandran; Peter H. Seeburg

December 1, 1985

Genetic mapping and diagnosis of haemophilia A achieved through a BclI polymorphism in the factor VIII gene

Nature, ISSN: 00280836

Jane Gitschier; Drayna; Tuddenham; Ray L. White; Lawn

December 1, 1985

Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes

Nature, ISSN: 00280836

Axel Ullrich; Bell; Ellson Y. Chen; Herrera; Petruzzelli; Dull; Gray; Lisa Coussens; Yu-Cheng Liao; TSUBOKAWA; Anthony J. Mason; Peter H. Seeburg; Grunfeld; Rosen; Ramachandran

December 1, 1985

Effect of interleukin 2, interferon-γ, and mitogens on the production of tumor necrosis factors α and β

Journal of Immunology, ISSN: 00221767

Nedwin; Svedersky; Timothy S. Bringman; Michael A. Palladino; David V. Goeddel

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