Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 15251 - 15300 OF 16237 RESULTS

April 2, 1990

Interaction of wild-type and catalytically inactive mutant forms of tissue-type plasminogen activator with human umbilical vein endothelial cell monolayers

Journal of Biological Chemistry, ISSN: 00219258

Vanitha Ramakrishnan; Sinicropi; Randall Dere; Darbonne; Bechtol; Baker

April 1, 1990

Plasminogen Activator Activities of Equimolar Complexes of Streptokinase with Variant Recombinant Plasminogens

Biochemistry, ISSN: 15204995 00062960

Donald J. Davidson; Deborah L. Higgins; Francis J. Castellino

March 23, 1990

The human growth hormone receptor. Secretion from Escherichia coli and disulfide bonding pattern of the extracellular binding domain

Journal of Biological Chemistry, ISSN: 00219258

Fuh; Michael G. Mulkerrin; Bass; Nancy McFarland; Michael Brochier; James H. Bourell; Light; James A. Wells

March 22, 1990

Growth hormone–receptor gene in laron dwarfism

New England Journal of Medicine, ISSN: 15334406 00284793

Bass; James A. Wells; Serge Amselem; Philippe Duquesnoy; Olivier Attree; Giuseppe Novelli; Souad Bousnina; Marie-Catherine Postel-Vinay; Michel Goossens

March 1, 1990

Characterization of Murine Monoclonal Antibodies Reactive to Either the Human Epidermal Growth Factor Receptor or HER2/neu Gene Product

Cancer Research, ISSN: 15387445 00085472

Brian M. Fendly; Marcy Winget; Hudziak; Michael T. Lipari; Napier; Axel Ullrich

March 1, 1990

A General Method for Highly Selective Cross-Linking of Unprotected Polypeptides via pH-Controlled Modification of N-Terminal α-Amino Groups

Bioconjugate Chemistry, ISSN: 15204812 10431802

Wetzel; Roger Halualani; Stults; Quan

February 15, 1990

The effect of the one-chain to two-chain conversion in tissue plasminogen activator: Characterization of mutations at position 275

Thrombosis Research, ISSN: 00493848

Deborah L. Higgins; M.Christine Lamb; Young; Powers; Anderson

February 2, 1990

The Mel 14 antibody binds to the lectin domain of the murine peripheral lymph node homing receptor

Journal of Cell Biology, ISSN: 00219525

Bowen; Christopher Fennie; Lasky

February 2, 1990

Application of high-performance hydrophobic-interaction chromatography to the characterization of recombinant DNA-derived human growth hormone

Journal of Chromatography A, ISSN: 00219673

Shiaw-Lin Wu; William S. Hancock; Bohdan Pavlu; Par Gellerfors

February 1, 1990

Organization of the Human Cholesteryl Ester Transfer Protein Gene

Biochemistry, ISSN: 15204995 00062960

Luis B. Agellon; Elaine M. Quinet; Thomas G. Gillette; Maryanne L. Brown; Alan R. Tall; Drayna

January 23, 1990

Vectorial secretion of extracellular matrix proteins, matrix-degrading proteinases, and tissue inhibitor of metalloproteinases by endothelial cells

Journal of Biological Chemistry, ISSN: 00219258

Elaine N. Unemori; Karyn S. Bouhana; Zena Werb

January 19, 1990

Analysis of glycoprotein-derived oligosaccharides by high-pH anion-exchange chromatography

Journal of Chromatography A, ISSN: 00219673

Basa; Spellman

January 19, 1990

Automated evaluation of tryptic digest from recombinant human growth hormone using ultraviolet spectra and numeric peak information

Journal of Chromatography A, ISSN: 00219673

Hans-Jurgen P. Sievert; Wu Shiaw-Lin; Chloupek; William S. Hancock

January 15, 1990

Immunomodulatory and Toxic Effects of Free and Liposome-encapsulated Tumor Necrosis Factor a in Rats1

Cancer Research, ISSN: 15387445 00085472

Robert J. Debs; Henry J. Fuchs; Ramila Philip; Elisa N. Brunette; Nejat Düzgüneş; Judd E. Shellito; Liggitt; John R. Patton

January 15, 1990

Differential Regulation of Expression of Three Transforming Growth Factor 0 Species in Human Breast Cancer Cell Lines by Estradiol

Cancer Research, ISSN: 15387445 00085472

Arrick; Murray Korc; Rik Derynck

January 1, 1990

Comment: Duteplase not alteplase

DICP, Annals of Pharmacotherapy, ISSN: 10429611

Magnuson

January 1, 1990

GTP-binding Ypt1 protein and Ca2+ function independently in a cell-free protein transport reaction

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

David Baker; Wuestehube; Randy Schekman; David Botstein; Nava Segev

January 1, 1990

Radiofluorography: A method for rapid whole body autoradiography

Journal of Histotechnology, ISSN: 20460236 01478885

Hansen

January 1, 1990

Inhibin and activin locally regulate rat ovarian folliculogenesis

Endocrinology, ISSN: 19457170 00137227

Woodruff; Lyon; Hansen; Glenn C. Rice; Mather

January 1, 1990

Structural characterization of a recombinant CD4‐IgG hybrid molecule

European Journal of Biochemistry, ISSN: 14321033 00142956

Reed J. Harris; Karen L. Wagner; Spellman

January 1, 1990

Vectorial apical delivery and slow endocytosis of a glycolipid-anchored fusion protein in transfected MDCK cells

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Michael P. Lisanti; Caras; Gilbert; David Hanzel; Rodriguez-Boulan

January 1, 1990

Role of hemostatic defect during thrombolytic therapy with recombinant tissue-type plasminogen activator

Thrombosis Research, ISSN: 00493848

David Stump

January 1, 1990

Activin stimulates spermatogonial proliferation in germ-sertoli cell cocultures from immature rat testis

Endocrinology, ISSN: 19457170 00137227

Mather; Kenneth M. Attie; Woodruff; Glenn C. Rice; David M. Phillips

January 1, 1990

Downstream processing of proteins from mammalian cells.

Bioprocess technology, ISSN: 08887470

John R. Ogez; Stuart E. Builder

January 1, 1990

Connective tissue metabolism including cytokines

Current Opinion in Rheumatology, ISSN: 10408711

Elaine N. Unemori; Edward P. Amento

January 1, 1990

Hydroxyl hydrogen conformations in trypsin determined by the neutron diffraction solvent difference map method: Relative importance of steric and electrostatic factors in defining hydrogen-bonding geometries

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Anthony A. Kossiakoff; Shpungin; Sintchak

January 1, 1990

Heritable major histocompatibility complex class II-associated differences in production of tumor necrosis factor α: Relevance to genetic predisposition to systemic lupus erythematosus

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Chaim O. Jacob; Zdenka Fronek; Gail D. Lewis; May Koo; John A. Hansen; Hugh O. McDevitt

January 1, 1990

Functionally distinct insulin receptors generated by tissue-specific alternative splicing

EMBO Journal, ISSN: 02614189

Luitgard Mosthaf; Grako; Dull; Lisa Coussens; Axel Ullrich; Donald A. McClain

January 1, 1990

Chapter 31. The Impact of Biotechnology on Drug Discovery

Annual Reports in Medicinal Chemistry, ISSN: 00657743

Michael C. Venuti

January 1, 1990

Expression of cloned proteins in mammalian cells: regulation of cell-associated parameters.

Bioprocess technology, ISSN: 08887470

Mather; Tsao

January 1, 1990

A precise and rapid microtitre plate clot lysis assay: Methodology, kinetic modeling and measurement of catalytic constants for plasminogen activation during fibrinolysis

Thrombosis and Haemostasis, ISSN: 03406245

Andrew J.S. Jones; Meunier

January 1, 1990

Hormone phage: An enrichment method for variant proteins with altered binding properties

Proteins: Structure, Function and Bioinformatics, ISSN: 10970134 08873585

Bass; Ronald Greene; James A. Wells

January 1, 1990

Serotonin Receptor “Families” in the Central Nervous System: An Overview

Annals of the New York Academy of Sciences, ISSN: 17496632 00778923

Peroutka; ANNE W. SCHMIDT; Andrew J. Sleight; MELISSA A. HARRINGTON

January 1, 1990

Folding of eukaryotic proteins produced in Escherichia coli.

Genetic engineering, ISSN: 01963716

Robert F. Kelley; Winkler

January 1, 1990

Acidic fibroblast growth factor (HBGF‐1) stimulates DNA synthesis in primary rat hepatocyte cultures

Journal of Cellular Physiology, ISSN: 10974652 00219541

Houck; Reza Zarnegar; Stephanie J. Muga; George K. Michalopoulos

January 1, 1990

5’ -Phosphorylation of oligonucleotides with phosphorous acid in automated dna synthesis

Nucleosides and Nucleotides, ISSN: 07328311

James C. Marsters Jr.; Ng; Jhurani; Vasser; Norbert Bischofberger

January 1, 1990

Regional Distribution of α‐[3H]Amino‐3‐Hydroxy‐5‐Methylisoxazole‐4‐Propionic Acid Binding Sites in Rat Brain: Effect of Chemical Modification of SH– Groups in Tissue Sections

Journal of Neurochemistry, ISSN: 14714159 00223042

Michel Baudry; Daniel Monaghan; Carl Cotman; C.Anthony Altar

January 1, 1990

Quality control of rDNA-derived human tissue-type plasminogen activator.

Bioprocess technology, ISSN: 08887470

Andrew J.S. Jones; Robert L. Garnick

January 1, 1990

Preparation and Characterization of Conjugates of Recombinant CD4 and Deglycosylated Ricin A Chain Using Different Cross-Linkers

Bioconjugate Chemistry, ISSN: 15204812 10431802

Victor Ghetie; Mark A. Till; Maria-Ana Gnette; Thomas Tucker; James P. Porter; Patzer; James A. Richardson; Jonathan W. Uhr; Ellen S. Vitetta

January 1, 1990

Structural characterization by mass spectrometry of native and recombinant human relaxin

Biomedical and Environmental Mass Spectrometry, ISSN: 10969888 10529306

Stults; James H. Bourell; Eleanor Canova-Davis; Victor Ling; Laramee; Winslow; Patrick Griffin; Rinderknecht; Richard L. Vandlen

January 1, 1990

Intact antigen receptor-mediated generation of inositol phosphates and increased intracellular calcium in CD4-CD8- T lymphocytes from MRL lpr mice

Journal of Immunology, ISSN: 00221767

Ralph C. Budd; Genine Winslow; Sharon Inokuchi; John B. Imboden

January 1, 1990

The mtr locus is a two-gene operon required for transcription attenuation in the trp operon of Bacillus subtilis

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Paul Gollnick; Shuichi Ishino; Mitzi I. Kuroda; Henner; Yanofsky

January 1, 1990

Endothelial and leukocyte forms of IL-8: Conversion by thrombin and interactions with neutrophils

Journal of Immunology, ISSN: 00221767

Hébert; Francis W. Luscinskas; Jeanne-Marie Kiely; Luis; Darbonne; Bennett; Liu; Obin; Gimbrone Jr.; Baker

January 1, 1990

PDGF ligand and receptor gene expression during repair of arterial injury

Journal of Cell Biology, ISSN: 00219525

Mark W. Majesky; Michael A. Reidy; Daniel F. Bowen-Pope; Charles E. Hart; Josiah N. Wilcox; Schwartz

January 1, 1990

Purification and characterization of an inhibitor (soluble tumor necrosis factor receptor) for tumor necrosis factor and lymphotoxin obtained from the serum ultrafiltrates of human cancer patients

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Tetsuya Gatanaga; Chenduen Hwang; William J. Kohr; Fabio Cappuccini; Joseph A. Lucci III; Edward W. B. Jeffes; Rigdon Lentz; John Tomich; Robert S. Yamamoto; Gale A. Granger

January 1, 1990

Transforming growth factor‐α

Molecular Reproduction and Development, ISSN: 10982795 1040452X

Rik Derynck

January 1, 1990

Direct interaction of a ligand for the erbB2 oncogene product with the EGF receptor and p185erbB2

Science, ISSN: 00368075

Ruth Lupu; Ramon Colomer; Gerhard Zugmaier; Jay Sarup; Michael H. Shepard; Dennis J. Slamon; Marc E. Lippman

January 1, 1990

Transforming Growth Factor‐β Effect on Soft Tissue Repair

Annals of the New York Academy of Sciences, ISSN: 17496632 00778923

Arthur J. Ammann; L. Steven Beck; Leo Deguzman; Sue E. Hirabayashi; Wyne P. Lee; Lorrie L. Mcfatridge; Tue H. Nguyen; Yvette Xu; THOMAS A. MUSTOE

January 1, 1990

Structure and function of lipopolysaccharide binding protein

Science, ISSN: 00368075

Ralf R. Schumann; Leong; Gail W. Flaggs; Patrick W. Gray; Samuel D. Wright; John C. Mathison; Peter S. Tobias; Richard J. Ulevitch

January 1, 1990

The autocrine production of transforming growth factor-β1 during lymphocyte activation. A study with a monoclonal antibody-based ELISA

Journal of Immunology, ISSN: 00221767

Catherine Lucas; Bald; Brian M. Fendly; Mora-Worms; Figari; Patzer; Michael A. Palladino

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