Publications
Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.
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Industrial and Engineering Chemistry Research, ISSN: 15205045 08885885
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Activation loop dynamics are controlled by conformation-selective inhibitors of ERK2
Proceedings of the National Academy of Sciences of the United States of America,
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TAZ is required for lung alveolar epithelial cell differentiation after injury
JCI insight,
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Discovery of clinical candidate (1 R,4 r)-4-((R)-2-((S)-6-Fluoro-5 H-imidazo[5,1-A[isoindol-5-yl)-1-hydroxyethyl)cyclohexan-1-ol (Navoximod), a potent and selective inhibitor of indoleamine 2,3-dioxygenase 1
Journal of Medicinal Chemistry, ISSN: 00222623
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The Importance of Molecular Immune Investigation in Therapeutic Clinical Development for Biomarker Assessment
Journal of Crohn's and Colitis,
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A Stromal Niche Defined by Expression of the Transcription Factor WT1 Mediates Programming and Homeostasis of Cavity-Resident Macrophages
Immunity, ISSN: 10747613
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Robust network inference using response logic
Bioinformatics, ISSN: 13674803
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IL-17A is associated with the breakdown of the blood-brain barrier in relapsing-remitting multiple sclerosis
Journal of Neuroimmunology, ISSN: 01655728
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eLife, ISSN: 2050084X
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Annals of Oncology, ISSN: 15698041 09237534
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Genes, ISSN: 20734425
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Molecular Pharmaceutics, ISSN: 15438392
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Molecular Pharmaceutics, ISSN: 15438392
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Nature Methods, ISSN: 15487105 15487091
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The Lancet Oncology, ISSN: 14745488 14702045
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Effects of PI3K Inhibition on Afucosylated Antibody-Driven FcγRIIIa Events and Phospho-S6 Activity in NK Cells
Journal of Immunology,
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The Lancet Oncology, ISSN: 14745488 14702045
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Prognostic risk score for patients with relapsed or refractory chronic lymphocytic leukaemia treated with targeted therapies or chemoimmunotherapy: a retrospective, pooled cohort study with external validations
The Lancet Haematology,
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AAPS PharmSciTech, ISSN: 15309932
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Effect of concomitant dosing with acid-reducing agents and vemurafenib dose on survival in patients with BRAFV600 mutation–positive metastatic melanoma treated with vemurafenib ± cobimetinib
European Journal of Cancer, ISSN: 09598049
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Cell Reports, ISSN: 22111247
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Massive antibody discovery used to probe structure-function relationships of the essential outer membrane protein LptD
eLife,
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Mechanisms of immune-related adverse events associated with immune checkpoint blockade: Using germline genetics to develop a personalized approach
Genome Medicine,
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Atezolizumab plus bevacizumab versus sunitinib in patients with previously untreated metastatic renal cell carcinoma (IMmotion151): a multicentre, open-label, phase 3, randomised controlled trial
The Lancet, ISSN: 01406736
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Journal of Neuroscience, ISSN: 15292401
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BMC Cancer, ISSN: 14712407
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Interlaboratory Comparison of Hydrogen-Deuterium Exchange Mass Spectrometry Measurements of the Fab Fragment of NISTmAb
Analytical Chemistry, ISSN: 00032700
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Convergent genetic aberrations in murine and human T lineage acute lymphoblastic leukemias
PLoS Genetics,
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Aging Cell, ISSN: 14749726 14749718
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The Lancet Haematology, ISSN: 23523026
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Journal of Pharmacology and Experimental Therapeutics, ISSN: 15210103
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Cancer Chemotherapy and Pharmacology, ISSN: 14320843 03445704
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A phase 1, randomized, single-ascending-dose study to investigate the safety, tolerability, and pharmacokinetics of DSTA4637S, an anti-staphylococcus aureus thiomab antibody-antibiotic conjugate, in healthy volunteers
Antimicrobial Agents and Chemotherapy, ISSN: 00664804
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Atezolizumab plus cobimetinib and vemurafenib in BRAF-mutated melanoma patients
Nature Medicine, ISSN: 10788956
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Atezolizumab with or without cobimetinib versus regorafenib in previously treated metastatic colorectal cancer (IMblaze370): a multicentre, open-label, phase 3, randomised, controlled trial
The Lancet Oncology, ISSN: 14702045
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Coexpression of inhibitory receptors enriches for activated and functional CD8+ T cells in murine syngeneic tumor models
Cancer immunology research, ISSN: 23266066
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Effects of concomitant glucocorticoids in TOZURA, a common-framework study programme of subcutaneous tocilizumab in rheumatoid arthritis
Rheumatology,
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Genomic features of exceptional response in vemurafenib cobimetinib–treated patients with BRAFV600-mutated metastatic melanoma
Clinical Cancer Research, ISSN: 10780432
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In Vivo Assessment of Antibody-Dependent Enhancement of Influenza B Infection
Toxicological Sciences,
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Phase I study of the indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor navoximod (GDC-0919) administered with PD-L1 inhibitor (atezolizumab) in advanced solid tumors
Clinical Cancer Research, ISSN: 10780432
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A Flexible Approach for Context-Dependent Assessment of Quantitative Systems Pharmacology Models
CPT: Pharmacometrics and Systems Pharmacology,
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Molecular Genetics and Metabolism Reports, ISSN: 22144269
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eLife, ISSN: 2050084X
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Cell Reports, ISSN: 22111247
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IRF2 transcriptionally induces GSDMD expression for pyroptosis
Science Signaling, ISSN: 19450877
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Analytical and Bioanalytical Chemistry, ISSN: 16182650 16182642
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Organic Process Research and Development, ISSN: 1520586X 10836160
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Organic Process Research and Development, ISSN: 1520586X 10836160
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Bioconjugate Chemistry, ISSN: 15204812 10431802
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Blood, ISSN: 15280020
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