Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 201 - 250 OF 11836 RESULTS

mAbs, ISSN: 19420870 19420862
Yanli Yang; Sherry H. Yeh; Shravan Madireddi; Wadim Matochko; Chen Gu; Patricia Pacheco-Sanchez; Mark Ultsch; Gladys Boenig; Seth Harris; Brandon Leonard; Suzie Scales; Jing W. Zhu; Erin Christensen; Julie Q. Hang; Randall Brezski; Scot Marsters; Avi Ashkenazi; Sid Sukumaran; Henry Chiu; Rafael Cubas; Kim; Greg Lazar
Cyclodextrin Reduces Intravenous Toxicity of a Model Compound
Journal of Pharmaceutical Sciences, ISSN: 00223549
Priscilla Mantik; Minli Xie; Harvey Wong; Hank La; Ronald Steigerwalt; Uday Devanaboyina; Geoffrey Ganem; Danny Shih; John Flygare; Wayne Fairbrother; Paroma Chakravarty; David Russell; Gilberto E. Fernandez; Ajit Narang
Cancer Cell, ISSN: 18783686 15356108
Tuba N. Gide; Camelia Quek; Alexander M. Menzies; Annie T. Tasker; Ping Shang; Jeff Holst; Jason Madore; Su Yin Lim; Rebecca Velickovic; Matthew Wongchenko; Yibing Yan; Serigne Lo; Matteo S. Carlino; Alexander Guminski; Robyn P.M. Saw; Angel Pang; Helen M. McGuire; Umaimainthan Palendira; John F. Thompson; Helen Rizos; Ines Pires da Silva; Marcel Batten; Richard A. Scolyer; Georgina V. Long; James S. Wilmott
Durability of Diabetic Retinopathy Improvement with As-Needed Ranibizumab: Open-Label Extension of RIDE and RISE Studies
Ophthalmology, ISSN: 01616420
Jennifer K. Sun; Pin-wen Wang; Sarah Taylor; Zdenka Haskova
Journal of Molecular Biology, ISSN: 10898638 00222836
Mark Ultsch; Wei Li; Charles Eigenbrot; Paola Di Lello; Terry Lipari; Gerhardy; Andrew Ah Young; John Quinn; Yvonne Franke; Chen; Monica Beltran; Andy Peterson; Daniel Kirchhofer
Integrin Signaling in Cancer: Mechanotransduction, Stemness, Epithelial Plasticity, and Therapeutic Resistance
Cancer Cell, ISSN: 15356108
Jon Cooper; Filippo G Giancotti
Interaction of cell culture process parameters for modulating mAb afucosylation
Biotechnology and Bioengineering, ISSN: 00063592
Anh Nguyen Dang; Melissa Mun; Christopher M. Rose; Patrick Ahyow; Angela Meier; Wendy Sandoval; Inn Yuk
Quantifying the vial capping process: Residual seal force and container closure integrity
PDA Journal of Pharmaceutical Science and Technology, ISSN: 10797440
Robert Ovadia; Alexander Streubel; Yenny Webb-Vargas; Lea Ulland; Joerg Luemkemann; Kamila Rauch; Juergen Eder; Philippe Lam; Vassia Tegoulia; Yuh-Fun Maa
Quantitative X-Ray Microcomputed Tomography Assessment of Internal Tablet Defects
Journal of Pharmaceutical Sciences, ISSN: 00223549
Edward Yost; Pascal Chalus; Shawn Zhang; Stefanie Peter; Ajit Narang
Annals of the Rheumatic Diseases, ISSN: 14682060 00034967
Ajinkya Pawar; Rishi J. Desai; Daniel H. Solomon; Adrian J. Santiago Ortiz; Sara Gale; Min Bao; Khaled Sarsour; Sebastian Schneeweiss; Seoyoung C. Kim
Simulating an Anti–Vascular Endothelial Growth Factor Switch in Neovascular Age-Related Macular Degeneration: A HARBOR Subanalysis
Ophthalmology, ISSN: 01616420
Marco A. Zarbin; Min Tsuboi; Lauren Hill; Ivo Stoilov
Split-cakes, still delicious
PDA Journal of Pharmaceutical Science and Technology, ISSN: 10797440
Philippe Lam; Thomas Patapoff
Unexpected equivalent potency of a constrained chromene enantiomeric pair rationalized by co-crystal structures in complex with estrogen receptor alpha
Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X
Birong Zhang; James Kiefer; Robert Blake; Jae H. Chang; Steven J. Hartman; Ellen Ingalla; Tracy Kleinheinz; Vidhi Mody; Michelle Nannini; Dan Ortwine; Yingqing Ran; Amy Sambrone; Deepak Sampath; Maia Vinogradova; Yu Zhong Yao; Jerome C. Nwachukwu; Kendall W. Nettles; Tommy Lai; Jiangpeng Liao; Xiaoping Zheng; Hai Chen; Xiaojing Wang; Jun Liang
Durable remissions with obinutuzumab-based chemoimmunotherapy: Long-term follow-up of the phase 1b GALTON trial in CLL
Blood, ISSN: 00064971
Jennifer R. Brown; Susan O'Brien; C. Daniel Kingsley; Herbert Eradat; John M. Pagel; Jamie Hirata; Tammy McIver; Rodica Morariu-Zamfir; Thomas J. Kipps
EMBO Journal, ISSN: 14602075 02614189
David Castillo-Azofeifa; Elena N Fazio; Roy Nattiv; Hayley J Good; Tomas Wald; Michael A Pest; Frederic De Sauvage; Ophir D Klein; Samuel Asfaha
Characterizing and enhancing virus removal by protein A chromatography
Biotechnology and Bioengineering, ISSN: 00063592
Chinwei Pan; Alejandro Becerra-Arteaga; Ben Tran; Michael Chinn; Hua Wang; Qi Chen; Herbert Lutz; Min Zhang
Cambridge Quarterly of Healthcare Ethics, ISSN: 14692147 09631801
Ariella Kelman; Anna Kang; Brian Crawford
Journal of Proteome Research, ISSN: 15353907 15353893
Veronica Anania; Kebing Yu; Francesco Pingitore; Qingling Li; Christopher M. Rose; Peter Liu; Wendy Sandoval; Ann E. Herman; Jennie Lill; Rod Mathews
Journal of Biological Chemistry, ISSN: 1083351X 00219258
Aaron Nile; Rami Hannoush
American Journal of Physiology - Renal Physiology, ISSN: 15221466 03636127
Luke Xie; Georgios Koukos; Kai Barck; Oded Foreman; Wyne P. Lee; Bob Brendza; Jeff Eastham; Brent S. McKenzie; Andy Peterson; Rick Carano
Journal of Allergy and Clinical Immunology, ISSN: 10976825 00916749
Nicola A. Hanania; Bradley E. Chipps; Noelle Griffin; Bongin Yoo; Ahmar Iqbal; Thomas B. Casale
Quantitative neuroimaging measures of myelin in the healthy brain and in multiple sclerosis
Human Brain Mapping, ISSN: 10659471
Jonathan O'Muircheartaigh; Irene Vavasour; Emil Ljungberg; David K. B. Li; Alexander Rauscher; Victoria Levesque; Hideki Garren; David Clayton; Roger Tam; Traboulsee; Shannon Kolind
The Escherichia coli -barrel assembly machinery is sensitized to perturbations under high membrane fluidity
Journal of Bacteriology, ISSN: 00219193
Kelly M. Storek; Rajesh Vij; Dawei Sun; Peter Smith; James T. Koerber; Steven T. Rutherford
Tumor-Infiltrating Lymphocytes in Patients Receiving Trastuzumab/Pertuzumab-Based Chemotherapy: A TRYPHAENA Substudy
Journal of the National Cancer Institute,
Michail Ignatiadis; Gert G.G.M. Van Den Eynden; Salgado Roberto; Marco Fornili; Yacine Bareche; Christine Desmedt; Rothé; Maetens; David Venet; Esther Holgado; Virginia McNally; Astrid Kiermaier; Heidi Savage; Tim Wilson; Javier Cortes; Andreas Schneeweiss; Karen Willard-Gallo; Elia Biganzoli; Christos Sotiriou
Biotechnology Progress, ISSN: 15206033 87567938
Tomofumi Tadauchi; Cynthia Lam; Laura Liu; Yizhou Zhou; Danming Tang; Salina Louie; Brad Snedecor; Shahram Misaghi
Investigation of the absolute bioavailability and human mass balance of navoximod, a novel IDO1 inhibitor
British Journal of Clinical Pharmacology, ISSN: 03065251
Shuguang Ma; Julia Suchomel; Evelyn Yanez; Edward Yost; Xiaorong Liang; Rui Zhu; Hoa Le; Nicholas Siebers; Lori Joas; Roland Morley; Stephanie Royer Joo; Andrea Pirzkall; Laurent Salphati; Joseph A. Ware; Kari M. Morrissey
Production, characterization, and in vivo half-life extension of polymeric IgA molecules in mice
mAbs, ISSN: 19420862
Twyla Lombana; Sharmila Rajan; Julie A. Zorn; Danielle Mandikian; Eugene C. Chen; Alberto Estevez; Victor Yip; Daniel D. Bravo; Wilson Phung; Farzam Farahi; Sharon Viajar; Sophia Lee; Avinash Gill; Wendy Sandoval; Jianyong Wang; Claudio Ciferri; Andy Boswell; Marissa Matsumoto; Christoph Spiess
Protein conjugates and fusion proteins as ocular therapeutics
Drug Discovery Today, ISSN: 13596446
Shrenik C. Mehta; Robert Kelley; Devin Tesar
Safety analysis of rFVIIa with emicizumab dosing in congenital hemophilia A with inhibitors: Experience from the HAVEN clinical program
Journal of Thrombosis and Haemostasis, ISSN: 15387933
Gallia Levy; Elina Asikanius; Peter Kuebler; Soraya Benchikh El Fegoun; Sille Esbjerg; Stephanie Seremetis
Methods in Pharmacology and Toxicology, ISSN: 19406053 15572153
Jake Luoma; Graham Magill; Lokesh Kumar; Zakaria Yusoff
Enantioselective synthesis of GNE-6688, a potent and selective inhibitor of interleukin-2 inducible T-cell kinase (ITK)
Tetrahedron Letters, ISSN: 00404039
Jared Moore; Kevin Lau; Xiaofeng Xu; Yamin Zhang; Jason Burch
Bioinformatics, ISSN: 14602059 13674803
Kevin Y.X. Wang; Alexander M. Menzies; Ines P. Silva; James S. Wilmott; Yibing Yan; Matthew Wongchenko; Richard F. Kefford; Richard A. Scolyer; Georgina V. Long; Garth Tarr; Samuel Mueller; Jean Y.H. Yang
A flexible and scalable high-throughput platform for recombinant membrane protein production
Methods in Molecular Biology, ISSN: 10643745
Hui Xu; Thomas Clairfeuille; Christine C. Jao; Hoangdung Ho; Zach Sweeney; Jian Payandeh; Chris Koth
Autophagy of Sensory Neurons in the Trigeminal and Dorsal Root Ganglia of Cynomolgus Monkeys (Macaca fascicularis)
Toxicologic Pathology, ISSN: 01926233
Mark T. Butt; Reina Fuji; Mike Reichelt; Alok K. Sharma; Sarah Cramer
Bromodomains: a new target class for drug development
Nature Reviews Drug Discovery, ISSN: 14741776
Andrea Cochran; Andrew R. Conery; Robert J. Sims
Design of a brain-penetrant CDK4/6 inhibitor for glioblastoma
Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X
Sarah M. Bronner; Karl A. Merrick; Jeremy Murray; Laurent Salphati; John Moffat; Jodie Pang; Christopher Sneeringer; Nick Dompe; Patrick Cyr; Hans Purkey; Gladys de Leon Boenig; Jun Li; Aleksandr Kolesnikov; Larouche-Gauthier; Kwong Wah Lai; Xiaoli Shen; Samuel Aubert-Nicol; Yi-Chen Chen; Jonathan Cheong; James Crawford; Marc Hafner; Pouyan Haghshenas; Araz Jakalian; Jean-Philippe Leclerc; Ngiap-Kie Lim; Thomas O'Brien; Emile Plise; Shalan; Claudio Sturino; John Wai; Yang Xiao; Peter Yin; Zhao; Stephen Gould; Alan Olivero; Tim Heffron
Discovery of a C-8 hydroxychromene as a potent degrader of estrogen receptor alpha with improved rat oral exposure over GDC-0927
Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X
Sharada Labadie; Jun Li; Robert Blake; Jae H. Chang; Simon Goodacre; Steven J. Hartman; Weiling Liang; James Kiefer; Tracy Kleinheinz; Tommy Lai; Jiangpeng Liao; Dan Ortwine; Vidhi Mody; Nicholas C. Ray; Fabien Roussel; Maia Vinogradova; Siew Kuen Yeap; Birong Zhang; Xiaoping Zheng; Jason Zbieg; Jun Liang; Gina Wang
High-throughput protein analysis using negative stain electron microscopy and 2D classification
Methods in Molecular Biology, ISSN: 10643745
Chris Arthur; Claudio Ciferri
Identification and characterization of an octameric PEG-protein conjugate system for intravitreal long-acting delivery to the back of the eye
PLoS ONE,
Whitney Shatz; Phil Hass; Nikhil Peer; Maciej Paluch; Craig Blanchette; Guanghui Han; Wendy Sandoval; Ashley Morando; Kelly Loyet; Vladimir Bantseev; Helen Booler; Susan Crowell; Amrita Kamath; Justin Scheer; Robert Kelley
Impact of Surfactant and Surfactant-Polymer Interaction on Desupersaturation of Clotrimazole
Journal of Pharmaceutical Sciences, ISSN: 00223549
Wei Zhang; Siddhi S. Hate; David J. Russell; Hao Helen Hou; Karthik Nagapudi
Semiautomated small-scale purification method for high-throughput expression analysis of recombinant proteins
Methods in Molecular Biology, ISSN: 10643745
Edward Kraft; Yvonne Franke; Katharine Heeringa; Stephanie Shriver; Inna Zilberleyb; Christine Kugel; Trisha Dela Vega; Athena Wong; Bobby Brillantes; Claudio Ciferri; George Dutina; Grace Lee; Isabelle Lehoux; Zhong Rong Li; Lee Lior-Hoffmann; Jiyoung Hwang; Chris Lonergan; Lynn Martin; Kyle Mortara; Lananh Nguyen; Jian Payandeh; Andrew Perez; Jun Sampang; Lovejit Singh; Kurt Schroeder; Christine Tam; Shu Ti; Ye Naing Win; Krista Bowman
Time-to-Event Modeling of Peripheral Neuropathy: Platform Analysis of Eight Valine-Citrulline-Monomethylauristatin E Antibody–Drug Conjugates
CPT: Pharmacometrics and Systems Pharmacology,
Kagedal; Divya Samineni; Gillespie; Dan Lu; Bernard Fine; Sandhya Girish; Chunze Li; Jin Y. Jin
Journal of Clinical Oncology, ISSN: 15277755 0732183X
Federico Innocenti; Fang-Shu Ou; Xueping Qu; Tyler J. Zemla; Donna Niedzwiecki; Rachel Tam; Shilpi Mahajan; Richard M. Goldberg; Monica M. Bertagnolli; Charles D. Blanke; Hanna Sanoff; James Atkins; Blase Polite; Alan P. Venook; Heinz-Josef Lenz; Omar Kabbarah
Science, ISSN: 10959203 00368075
Meng He; Mira S. Chaurushiya; Webster; Sarah Kummerfeld; Rohit Reja; Subhra Chaudhuri; Jasmine Chen; Zora Modrusan; Benjamin Haley; Debbie Dugger; Jeff Eastham; Shari Lau; Anwesha Dey; Roger Caothien; Meron Roose-Girma; Kim Newton; Vishva Dixit
A Rapid High-Sensitivity Reversed -Phase Ultra High Performance Liquid Chromatography Mass Spectrometry Method for Assessing Polysorbate 20 Degradation in Protein Therapeutics
Journal of Pharmaceutical Sciences, ISSN: 00223549
Ying Cheng; Mark Hu; Camellia Zamiri; Toshiro Carcelen; Barthelemy Demeule; Anthony Tomlinson; Jie Gu; Yinges Yigzaw; Matt Kalo; X. Christopher Yu
mAbs, ISSN: 19420870 19420862
Shan Chung; Van Nguyen; Linda Lin; Julien Lafrance-Vanasse; Suzie Scales; Kevin Lin; Rong Deng; Kathi Williams; Gizette Sperinde; Juan Jenny Li; Kai Zheng; Sid Sukumaran; Devin Tesar; James A. Ernst; Sally Fischer; Greg Lazar; Saileta Prabhu; An Song
Cellular mechanisms of etrolizumab treatment in inflammatory bowel disease
Frontiers in Pharmacology,
Charlotte Lichnog; Sha Klabunde; Emily Becker; Franklin Fuh; Philipp Tripal; Raja Atreya; Entcho Klenske; Rich Erickson; Henry Chiu; Chae Reed; Shan Chung; Clemens Neufert; Imke Atreya; Jacqueline McBride; Markus F. Neurath; Sebastian Zundler
Haemophilia, ISSN: 13652516 13518216
Johnny N. Mahlangu; Johannes Oldenburg; Michael U. Callaghan; Midori Shima; Mancuso; Peter Trask; Michael Recht; Claudia Garcia; Renchi Yang; Michaela Lehle; Harrison Macharia; Elina Asikanius; Gallia Levy; Kruse-Jarres; Sylvia von Mackensen
Current Medical Research and Opinion, ISSN: 14734877 03007995
Jason P. Swindle; Yaping Xu; Yunming Mu; Paul Solari
Trends in Cancer, ISSN: 24058033
Philamer C. Calses; James Crawford; Jennie Lill; Anwesha Dey