Publications
Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.
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Design of a brain-penetrant CDK4/6 inhibitor for glioblastoma
Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X
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Discovery of a C-8 hydroxychromene as a potent degrader of estrogen receptor alpha with improved rat oral exposure over GDC-0927
Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X
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High-throughput protein analysis using negative stain electron microscopy and 2D classification
Methods in Molecular Biology, ISSN: 10643745
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Identification and characterization of an octameric PEG-protein conjugate system for intravitreal long-acting delivery to the back of the eye
PLoS ONE,
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Impact of Surfactant and Surfactant-Polymer Interaction on Desupersaturation of Clotrimazole
Journal of Pharmaceutical Sciences, ISSN: 00223549
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Semiautomated small-scale purification method for high-throughput expression analysis of recombinant proteins
Methods in Molecular Biology, ISSN: 10643745
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Time-to-Event Modeling of Peripheral Neuropathy: Platform Analysis of Eight Valine-Citrulline-Monomethylauristatin E Antibody–Drug Conjugates
CPT: Pharmacometrics and Systems Pharmacology,
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Journal of Clinical Oncology, ISSN: 15277755 0732183X
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Science, ISSN: 10959203 00368075
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A Rapid High-Sensitivity Reversed -Phase Ultra High Performance Liquid Chromatography Mass Spectrometry Method for Assessing Polysorbate 20 Degradation in Protein Therapeutics
Journal of Pharmaceutical Sciences, ISSN: 00223549
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mAbs, ISSN: 19420870 19420862
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Cellular mechanisms of etrolizumab treatment in inflammatory bowel disease
Frontiers in Pharmacology,
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Haemophilia, ISSN: 13652516 13518216
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Current Medical Research and Opinion, ISSN: 14734877 03007995
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Trends in Cancer, ISSN: 24058033
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Clinical Rheumatology, ISSN: 14349949 07703198
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Clinical Cancer Research, ISSN: 15573265 10780432
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Pharmacokinetics of trastuzumab emtansine (T-DM1) as a single agent or in combination with pertuzumab in HER2-positive breast cancer patients with recurrent or locally advanced metastatic breast cancer
Cancer Chemotherapy and Pharmacology, ISSN: 03445704
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Angewandte Chemie - International Edition, ISSN: 15213773 14337851
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RIP1 inhibition blocks inflammatory diseases but not tumor growth or metastases
Cell Death and Differentiation, ISSN: 13509047
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Journal of Medicinal Chemistry, ISSN: 15204804 00222623
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Tetrahedron, ISSN: 14645416 00404020
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Ophthalmology, ISSN: 15494713 01616420
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trackr: A Framework for Enhancing Discoverability and Reproducibility of Data Visualizations and Other Artifacts in R
Journal of Computational and Graphical Statistics, ISSN: 10618600
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Methods in Molecular Biology, ISSN: 10643745
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Atezolizumab plus cobimetinib and vemurafenib in BRAF-mutated melanoma patients
Nature Medicine, ISSN: 10788956
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Correction: First-in-human phase 1 study of the BTK inhibitor GDC-0853 in relapsed or refractory B-cell NHL and CLL (Oncotarget(2018) 9 (13023 -13035) DOI: 10.18632/oncotarget.24310)
Oncotarget,
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Development of Potent and Selective Pyrazolopyrimidine IRAK4 Inhibitors
Journal of Medicinal Chemistry, ISSN: 00222623
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Fluorescent indomethacin-dansyl conjugates utilize the membrane-binding domain of cyclooxygenase-2 to block the opening to the active site
Journal of Biological Chemistry, ISSN: 00219258
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Palladium-catalyzed enantioselective decarboxylative allylic alkylation of fully substituted: N -acyl indole-derived enol carbonates
Chemical Science, ISSN: 20416520
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Palladium-catalyzed α,β-dehydrogenation of acyclic ester equivalents promoted by a novel electron deficient phosphinooxazoline ligand
Tetrahedron, ISSN: 00404020
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Pharmacokinetic and exposure–response analysis of pertuzumab in patients with HER2-positive metastatic gastric or gastroesophageal junction cancer
Cancer Chemotherapy and Pharmacology, ISSN: 03445704
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Prediction of Human Pharmacokinetics of Antibody–Drug Conjugates From Nonclinical Data
Clinical and Translational Science, ISSN: 17528054
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Probing interaction of lipid-modified wnt protein and its receptors by ELISA
Methods in Molecular Biology, ISSN: 10643745
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Safety, clinical activity and biomarker assessments of atezolizumab from a Phase I study in advanced/recurrent ovarian and uterine cancers
Gynecologic Oncology, ISSN: 00908258
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Safety, Tolerability, and Pharmacokinetics of GDC-0276, a Novel Na
Clinical Drug Investigation, ISSN: 11732563
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The safety evaluation of long-acting ocular delivery systems
Drug Discovery Today, ISSN: 13596446
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Unequal absorption of radiolabeled and nonradiolabeled drug from the oral dose leads to incorrect estimates of drug absorption and circulating metabolites in a mass balance study
Drug Metabolism Letters, ISSN: 18723128
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Respiration, ISSN: 14230356 00257931
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Biochimie, ISSN: 61831638 03009084
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Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
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Nature Immunology, ISSN: 15292916 15292908
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Thorax, ISSN: 14683296 00406376
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Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
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JAMA Oncology, ISSN: 23742445 23742437
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Oncologist, ISSN: 1549490X 10837159
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Oncologist, ISSN: 1549490X 10837159
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Protein and Peptide Letters, ISSN: 18755305 09298665
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Journal of Immunology, ISSN: 15506606 00221767
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Bioorganic and Medicinal Chemistry Letters, ISSN: 14643405 0960894X
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