Genentech takes the health and safety of our patients, customers, employees and local communities very seriously, and we are actively responding to the global COVID-19 pandemic. For more, please visit our COVID-19 response page.

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 201 - 250 OF 12129 RESULTS

CBP/p300 drives the differentiation of regulatory T cells through transcriptional and non-transcriptional mechanisms
Cancer Research, ISSN: 00085472
Joseph Castillo; Esther Wu; Christopher Lowe; Shrividhya Srinivasan; Mccord; Marie-Claire Wagle; Sangeeta Jayakar; Melissa Gonzalez Edick; Jeff Eastham; Bonnie Liu; Katherine E. Hutchinson; Wendell Jones; Matthew P. Stokes; Somayeh S. Tarighat; Tom Holcomb; Andrew Glibicky; Anthony Romero; Steven Magnuson; Shih-Min A. Huang; Vicki Plaks; Jennifer Giltnane; Mark Lackner; Zineb Mounir
Prognostic impact of natural killer cell count in follicular lymphoma and diffuse large b-cell lymphoma patients treated with immunochemotherapy
Clinical Cancer Research, ISSN: 10780432
Magdalena Klanova; Mikkel Z. Oestergaard; Marek Trneny; Wolfgang Hiddemann; Robert Marcus; Laurie H. Sehn; Umberto Vitolo; Alexandra Bazeos; Valentin Goede; Harald Zeuner; Andrea Knapp; Deniz Sahin; Nathalie Spielewoy; Chris Bolen; Andres Cardona; Christian Klein; Jeffrey M. Venstrom; Tina Nielsen; Guenter Fingerle-Rowson
Annals of Oncology, ISSN: 15698041 09237534
Oliveira; Saura; Nuciforo; Calvo; Andersen; Passos-Coelho; Gil Gil; Bermejo; Debra Patt; Eva Ciruelos; Lorena de la Peña; Xu; Matthew Wongchenko; Shi; Stina Singel; Isakoff
Journal of Clinical Oncology, ISSN: 15277755 0732183X
Heinz-Josef Lenz; Fang-Shu Ou; Alan P. Venook; Hochster; Donna Niedzwiecki; Richard M. Goldberg; Robert J. Mayer; Monica M. Bertagnolli; Charles D. Blanke; Tyler J. Zemla; Xueping Qu; Pratyaksha Wirapati; Sabine Tejpar; Federico Innocenti; Omar Kabbarah
Industrial and Engineering Chemistry Research, ISSN: 15205045 08885885
Yuan Jin; S. Joe Qin; Qiang Huang; Victor Saucedo; Zheng Li; Angela Meier; Siddhartha Kundu; Bri Lehr; Salim Charaniya
Activation loop dynamics are controlled by conformation-selective inhibitors of ERK2
Proceedings of the National Academy of Sciences of the United States of America,
Laurel M. Pegram; Jennifer C. Liddle; Yao Xiao; Maria Hoh; Johannes Rudolph; Dylan B. Iverson; Guy Vigers; Darin Smith; Hailong Zhang; Weiru Wang; John Moffat; Natalie G. Ahn
TAZ is required for lung alveolar epithelial cell differentiation after injury
JCI insight,
Tianhe Sun; Zhiyu Huang; Hua Zhang; Clara Posner; Guiquan Jia; Thiru Ramalingam; Min Xu; Hans Brightbill; Jackson Egen; Anwesha Dey; Joe Arron
Discovery of clinical candidate (1 R,4 r)-4-((R)-2-((S)-6-Fluoro-5 H-imidazo[5,1-A[isoindol-5-yl)-1-hydroxyethyl)cyclohexan-1-ol (Navoximod), a potent and selective inhibitor of indoleamine 2,3-dioxygenase 1
Journal of Medicinal Chemistry, ISSN: 00222623
Sanjeev Kumar; Jesse P. Waldo; Firoz A. Jaipuri; Agnieszka Marcinowicz; Clarissa Van Allen; James Adams; Tanay Kesharwani; Xiaoxia Zhang; Richard Metz; Angela Oh; Seth Harris; Mario R. Mautino
The Importance of Molecular Immune Investigation in Therapeutic Clinical Development for Biomarker Assessment
Journal of Crohn's and Colitis,
Christopher A. Lamb; John C Mansfield; John A. Kirby; Mary Keir
A Stromal Niche Defined by Expression of the Transcription Factor WT1 Mediates Programming and Homeostasis of Cavity-Resident Macrophages
Immunity, ISSN: 10747613
Matthew B. Buechler; Ki-Wook Kim; Emily J. Onufer; Jesse W. Williams; Christine C. Little; Claudia Dominguez; Qingling Li; Wendy Sandoval; Jon Cooper; Charles Harris; Melissa Junttila; Gwendalyn J. Randolph; Shannon Turley
Robust network inference using response logic
Bioinformatics, ISSN: 13674803
Torsten Gross; Matthew Wongchenko; Yibing Yan; Nils Blüthgen
IL-17A is associated with the breakdown of the blood-brain barrier in relapsing-remitting multiple sclerosis
Journal of Neuroimmunology, ISSN: 01655728
Francesca Setiadi; Alexander Abbas; Surinder Jeet; Kit Wong; Antje Bischof; Ivan Peng; James Lee; Meire Bremer; Erica L. Eggers; Jason DeVoss; Tracy Staton; Ann Herman; H. -Christian von Büdingen; Michael Townsend
eLife, ISSN: 2050084X
Junghyun Lim; Hyunjoo Park; Jason Heisler; Timurs Maculins; Meron Roose-Girma; Min Xu; Brent McKenzie; Menno van Lookeren Campagne; Kim Newton; Aditya Murthy
Annals of Oncology, ISSN: 15698041 09237534
Matthew D. Hellmann; Kim; Lee; Goh; Miller; Do-Youn Oh; Rahima Jamal; Chee; Laura Q.M. Chow; Gainor; Jayesh Desai; Benjamin Solomon; Meghna Das Thakur; Bethany Pitcher; Paul Foster; Genevive Hernandez; Matthew Wongchenko; Edward Cha; Bang; Siu; Bendell
Genes, ISSN: 20734425
Ze Zhang; Danni Luo; Xue Zhong; Jin Huk Choi; Yuanqing Ma; Stacy Wang; Elena Mahrt; Wei Guo; Eric Stawiski; Zora Modrusan; Somasekar Seshagiri; Payal Kapur; Gary C. Hon; James Brugarolas; Tao Wang
Molecular Pharmaceutics, ISSN: 15438392
Joseph A. O'Donoghue; Daniel C. Danila; Neeta Pandit-Taskar; Volkan Beylergil; Sarah M. Cheal; Stephen E. Fleming; Josef J. Fox; Shutian Ruan; Pat B. Zanzonico; Govind Ragupathi; Serge K. Lyashchenko; Simon P. Williams; Scher; Bernard Fine; John L. Humm; Steven M. Larson; Michael J. Morris; Jorge A. Carrasquillo
Molecular Pharmaceutics, ISSN: 15438392
David A. Hirsh; Anuradha V. Wijesekara; Scott L. Carnahan; Ivan Hung; Joe Lubach; Karthik Nagapudi; Aaron J. Rossini
Nature Methods, ISSN: 15487105 15487091
Glenn R. Masson; John E. Burke; Natalie G. Ahn; Ganesh Srinivasan Anand; Christoph H. Borchers; Sébastien Brier; George M. Bou-Assaf; John R. Engen; S. Walter Englander; Johan Faber; Rachel Garlish; Patrick Griffin; Michael L. Gross; Miklos Guttman; Yoshitomo Hamuro; Albert J.R. Heck; Damian Houde; Roxana E. Iacob; Thomas J. D. Jørgensen; Igor A. Kaltashov; Judith P. Klinman; Lars Konermann; Petr Man; Leland Mayne; Bruce D. Pascal; Dana Reichmann; Mark Skehel; Joost Snijder; Timothy S. Strutzenberg; Eric S. Underbakke; Cornelia Wagner; Thomas E. Wales; Ben Walters; David D. Weis; Derek J. Wilson; Patrick L. Wintrode; Zhongqi Zhang; Jie Zheng; David C. Schriemer; Kasper D. Rand
The Lancet Oncology, ISSN: 14745488 14702045
Howard West; Michael McCleod; Maen Hussein; Alessandro Morabito; Achim Rittmeyer; Henry J Conter; Hans-Georg Kopp; Davey B Daniel; Steven McCune; Tarek Mekhail; Alona Zer; Niels Reinmuth; Ahad Sadiq; Alan Sandler; Wei Lin; Tania Ochi Lohmann; Venice Archer; Lijia Wang; Marcin Kowanetz; Federico Cappuzzo
Effects of PI3K Inhibition on Afucosylated Antibody-Driven FcγRIIIa Events and Phospho-S6 Activity in NK Cells
Journal of Immunology,
Valentina Romeo; Sarah Gierke; Kyle A. Edgar; Scot D. Liu
The Lancet Oncology, ISSN: 14745488 14702045
Herve Tilly; Morschhauser; Nancy L. Bartlett; Amitkumar Mehta; Gilles Salles; Corinne Haioun; Javier Munoz; Andy I Chen; Kathryn S. Kolibaba; Dan Lu; Mark Yan; Elicia Penuel; Jamie Hirata; Calvin Lee; Jeff P. Sharman
Prognostic risk score for patients with relapsed or refractory chronic lymphocytic leukaemia treated with targeted therapies or chemoimmunotherapy: a retrospective, pooled cohort study with external validations
The Lancet Haematology,
Jacob D Soumerai; Ai Ni; Mohamed Darif; Anil Londhe; Guan Xing; Yong Mun; Neil E Kay; Tait D Shanafelt; Kari G Rabe; John C. Byrd; Chanan-Khan; Richard Furman; Hillmen; Jeffrey Jones; John F. Seymour; Jeff P. Sharman; Lucille Ferrante; Mehrdad Mobasher; Thomas Stark; Vijay Reddy; Lyndah K Dreiling; Pankaj Bhargava; Angela Howes; Danelle F James; Zelenetz
AAPS PharmSciTech, ISSN: 15309932
Samarth D. Thakore; Poonam Singh Thakur; Ganesh Shete; Rahul Gangwal; Ajit Narang; Abhay T. Sangamwar; Arvind Kumar Bansal
Effect of concomitant dosing with acid-reducing agents and vemurafenib dose on survival in patients with BRAFV600 mutation–positive metastatic melanoma treated with vemurafenib ± cobimetinib
European Journal of Cancer, ISSN: 09598049
Karl Lewis; Axel Hauschild; James Larkin; Antoni Ribas; Keith Flaherty; Grant A. McArthur; Brigitte Dréno; Edward McKenna; Qian Zhu; Yong Mun; Paolo A. Ascierto
Cell Reports, ISSN: 22111247
Hsu; Sébastien Tabariès; Radia Johnson; Sylvia Andrzejewski; Julien Senecal; Camille Lehuédé; Matthew G. Annis; Ma; Sandra Völs; LeeAnn Ramsay; Remi Froment; Anie Monast; Ian R. Watson; Zvi Granot; Jones; Julie St-Pierre; Siegel
Massive antibody discovery used to probe structure-function relationships of the essential outer membrane protein LptD
eLife,
Kelly Storek; Joyce Chan; Rajesh Vij; Nancy Chiang; Zhonghua Lin; Jack Bevers; Chris Koth; Jean-Michel Vernes; Gloria Meng; Peter Yin; Heidi Ackerly Wallweber; Olivier Dalmas; Stephanie Shriver; Christine Tam; Kellen Schneider; Dhaya Seshasayee; Gerry Nakamura; Peter Smith; Jian Payandeh; JT Koerber; Laetitia Comps-Agrar; Steven Rutherford
Mechanisms of immune-related adverse events associated with immune checkpoint blockade: Using germline genetics to develop a personalized approach
Genome Medicine,
Zia Khan; Christian Hammer; Ellie Guardino; G. Scott Chandler; Matthew Albert
Atezolizumab plus bevacizumab versus sunitinib in patients with previously untreated metastatic renal cell carcinoma (IMmotion151): a multicentre, open-label, phase 3, randomised controlled trial
The Lancet, ISSN: 01406736
Brian I. Rini; Thomas Powles; Michael B. Atkins; Bernard Escudier; David McDermott; Cristina Suárez; Sergio Bracarda; Walter M. Stadler; Frede Donskov; Jae-Lyun Lee; Robert E. Hawkins; Alain Ravaud; Boris Alekseev; Michael D. Staehler; Motohide Uemura; Ugo De Giorgi; Begoña Mellado; Camillo Porta; Melichar; Howard Gurney; Jens Bedke; Toni K. Choueiri; Francis Parnis; Tarik Khaznadar; Alpa Thobhani; Shi Li; Elisabeth Piault-Louis; Gretchen Frantz; Mahrukh Huseni; Christina Schiff; Marjorie Green; Robert J. Motzer
Journal of Neuroscience, ISSN: 15292401
Daniel Fleck; Lilian Phu; Erik Verschueren; Trent Hinkle; Mike Reichelt; Tushar Bhangale; Benjamin Haley; Yuanyuan Wang; Rob Graham; Don Kirkpatrick; Morgan Sheng; Baris Bingol
BMC Cancer, ISSN: 14712407
Sumanta Kumar Pal; Jun Gong; Shivani K. Mhatre; Wenny Lin; Andy Surinach; Sarika Ogale; Rini Vohra; Herschel Wallen; Daniel George
Interlaboratory Comparison of Hydrogen-Deuterium Exchange Mass Spectrometry Measurements of the Fab Fragment of NISTmAb
Analytical Chemistry, ISSN: 00032700
Jeffrey W. Hudgens; Elyssia S. Gallagher; Ioannis Karageorgos; Kyle W. Anderson; James J. Filliben; Richard Y.-C. Huang; Guodong Chen; George M. Bou-Assaf; Alfonso Espada; Michael J. Chalmers; Eduardo Harguindey; Hui-Min Zhang; Ben Walters; Jennifer Zhang; John Venable; Caitlin Steckler; Inhee Park; Ansgar Brock; Xiaojun Lu; Ratnesh Pandey; Arun Chandramohan; Ganesh Srinivasan Anand; Sasidhar N. Nirudodhi; Justin B. Sperry; Jason C. Rouse; James A. Carroll; Kasper D. Rand; Ulrike Leurs; David D. Weis; Mohammed A. Al-Naqshabandi; Tyler S. Hageman; Daniel Deredge; Patrick L. Wintrode; Malvina Papanastasiou; John D. Lambris; Sheng Li; Sarah Urata
Convergent genetic aberrations in murine and human T lineage acute lymphoblastic leukemias
PLoS Genetics,
Benjamin J. Huang; Anica M. Wandler; Lauren K. Meyer; Monique Dail; Anneleen Daemen; Deepak Sampath; Qing Li; Xinyue Wang; Jasmine C. Y. Wong; Joy Nakitandwe; James R. Downing; Jinghui Zhang; Barry S. Taylor; Kevin Shannon
Aging Cell, ISSN: 14749726 14749718
Lifen Wang; Sonnet S. Davis; Martin Borch Jensen; Imilce A. Rodriguez-Fernandez; Cagsar Apaydin; Gábor Juhász; Bradford W. Gibson; Birgit Schilling; Arvind Ramanathan; Sina Ghaemmaghami; Heinrich Jasper
The Lancet Haematology, ISSN: 23523026
Steven W Pipe; Midori Shima; Michaela Lehle; Amy Shapiro; Sammy Chebon; Katsuyuki Fukutake; Nigel S. Key; Agnès Portron; Christophe Schmitt; Maria Podolak-Dawidziak; Nives Selak Bienz; Cedric Hermans; Avrita Campinha-Bacote; Anna Kiialainen; Kathelijne Peerlinck; Gallia Levy; Jiménez-Yuste
Journal of Pharmacology and Experimental Therapeutics, ISSN: 15210103
Harvey Wong; Lichuan Liu; Wenjun Ouyang; Yuzhong Deng; Matthew Wright; Marcel Hop
Cancer Chemotherapy and Pharmacology, ISSN: 14320843 03445704
Whitney P. Kirschbrown; Kagedal; Wang; Lars Lindbom; Adam Knott; Rachelle Mack; Sharareh Monemi; Ihsan Nijem; Sandhya Girish; Christie Freeman; Fumagalli; Robin McConnell; Guy Jerusalem; Chris Twelves; Baselga; Gunter Von Minckwitz; José Bines; Amit Garg
A phase 1, randomized, single-ascending-dose study to investigate the safety, tolerability, and pharmacokinetics of DSTA4637S, an anti-staphylococcus aureus thiomab antibody-antibiotic conjugate, in healthy volunteers
Antimicrobial Agents and Chemotherapy, ISSN: 00664804
Melicent Peck; Michael E. Rothenberg; Rong Deng; Nicholas Lewin-Koh; Gaohong She; Amrita Kamath; Montse Carrasco-Triguero; Ola Saad; Aide Castro; Lisa Teufel; Daniel S. Dickerson; Marisa Leonardelli; Jorge Tavel
Atezolizumab plus cobimetinib and vemurafenib in BRAF-mutated melanoma patients
Nature Medicine, ISSN: 10788956
Ryan J. Sullivan; Omid Hamid; Rene Gonzalez; Jeffery R. Infante; Manish R. Patel; F. Stephen Hodi; Karl Lewis; Hussein Tawbi; Genevive Hernandez; Matthew Wongchenko; YiMeng Chang; Louise Roberts; Marcus Ballinger; Yibing Yan; Edward Cha; Patrick Hwu
Atezolizumab with or without cobimetinib versus regorafenib in previously treated metastatic colorectal cancer (IMblaze370): a multicentre, open-label, phase 3, randomised, controlled trial
The Lancet Oncology, ISSN: 14702045
Cathy Eng; Tae Won Kim; Bendell; Guillem Argiles; Niall C. Tebbutt; Maria Di Bartolomeo; Alfredo Falcone; Marwan Fakih; Kozloff; Neil H. Segal; Alberto Sobrero; Yibing Yan; Ilsung Chang; Anne Uyei; Louise Roberts; Fortunato Ciardiello; Ahn; Jamil Asselah; Badarinath; Baijal; Begbie; Berry; Jean-Luc Canon; Carbone; Andrés Cervantes; Cha; Chang; Chaudhry; Chmielowska; Cho; Chu; Couture; Cultrera; David Cunningham; Eric Van Cutsem; Cuyle; Davies; Dowden; Dvorkin; Vinod Ganju; Garcia; Kerr; Kim; King; Kortmansky; Kozloff; Lam; Lee; Lee; Lesperance; Luppi; Ma; Evaristo Maiello; Mandanas; John Marshall; Marx; Mullamitha; Nechaeva; Park; Pavlakis; Ponce; Potemski; Raouf; James A. Reeves; Segal; Siena; Smolin; Streb; Strickland; Szutowicz-Zielinska; Tabernero; Tan; Valera; Van den Eynde; Vergauwe; Vickers; Womack; Wroblewska; Young
Coexpression of inhibitory receptors enriches for activated and functional CD8+ T cells in murine syngeneic tumor models
Cancer immunology research, ISSN: 23266066
Huizhong Xiong; Stephanie Mittman; Ryan Rodriguez; Patricia Pacheco-Sanchez; Marina Moskalenko; Yagai Yang; Justin Elstrott; Alex Ritter; Sören Müller; Dorothee Nickles; Teresita L. Arenzana; Aude-Helene Capietto; Lelia Delamarre; Zora Modrusan; Sascha Rutz; Ira Mellman; Rafael Cubas
Effects of concomitant glucocorticoids in TOZURA, a common-framework study programme of subcutaneous tocilizumab in rheumatoid arthritis
Rheumatology,
Ernest Choy; Roberto Caporali; Ricardo Xavier; Bruno Fautrel; Raimón Sanmarti; Bao; Jenny Devenport; Attila Pethö-Schramm
Genomic features of exceptional response in vemurafenib cobimetinib–treated patients with BRAFV600-mutated metastatic melanoma
Clinical Cancer Research, ISSN: 10780432
Yibing Yan; Matthew Wongchenko; Caroline Robert; James Larkin; Paolo A. Ascierto; Brigitte Dréno; Michele Maio; Claus Garbe; Paul B. Chapman; Jeffrey A. Sosman; Zhen Shi; Hartmut Koeppen; Jessie Hsu; Ilsung Chang; Ivor Caro; Isabelle Rooney; Grant A. McArthur; Antoni Ribas
In Vivo Assessment of Antibody-Dependent Enhancement of Influenza B Infection
Toxicological Sciences,
Gautham K. Rao; Rodney Prell; Steven Laing; Stefanie C M Burleson; Allen Nguyen; Jacqueline McBride; Crystal Zhang; Daniel Sheinson; Wendy Halpern
Phase I study of the indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor navoximod (GDC-0919) administered with PD-L1 inhibitor (atezolizumab) in advanced solid tumors
Clinical Cancer Research, ISSN: 10780432
Kyung Hae Jung; Patricia M. LoRusso; Howard A. Burris; Michael S. Gordon; Yung-Jue Bang; Matthew D. Hellmann; Andrés Cervantes; Maria Ochoa de Olza; Aurélien Marabelle; Stephen Hodi; Myung-Ju Ahn; Leisha A. Emens; Fabrice Barlesi; Omid Hamid; Calvo; David McDermott; Hatem Soliman; Ina Rhee; Ray Lin; Tony Pourmohamad; Julia Suchomel; Amy Tsuhako; Kari M. Morrissey; Sami Mahrus; Roland Morley; Andrea Pirzkall; Lindsey Davis
A Flexible Approach for Context-Dependent Assessment of Quantitative Systems Pharmacology Models
CPT: Pharmacometrics and Systems Pharmacology,
Saroja Ramanujan; Jason R. Chan; Christina M. Friedrich; Craig J. Thalhauser
Molecular Genetics and Metabolism Reports, ISSN: 22144269
Kim R. Simpfendorfer; Wentian Li; Andrew Shih; Hongxiu Wen; Harini P. Kothari; Edward A. Einsidler; Art Wuster; Julie Hunkapiller; Tim Behrens; Rob Graham; Michael Townsend; Doron M. Behar; Rui Hu; Elliott Greenspan; Peter K. Gregersen
eLife, ISSN: 2050084X
Ganapati Hegde; Cecile de la Cruz; Jennifer Giltnane; Lisa Crocker; Avinashnarayan Venkatanarayan; Gabriele Schaefer; Debra Dunlap; Joerg D. Hoeck; Robert Piskol; Florian Gnad; Zora Modrusan; Frederic De Sauvage; Chris Siebel; Erica Jackson
Cell Reports, ISSN: 22111247
Jieqiong Zhang; Webster; Debbie Dugger; Tanya Goncharov; Meron Roose-Girma; Jeffrey Hung; Youngsu Kwon; Domagoj Vucic; Kim Newton; Vishva Dixit
IRF2 transcriptionally induces GSDMD expression for pyroptosis
Science Signaling, ISSN: 19450877
Nobuhiko Kayagaki; Bettina L. Lee; Irma Stowe; Opher S. Kornfeld; Karen O'Rourke; Kathleen M. Mirrashidi; Benjamin Haley; Colin Watanabe; Meron Roose-Girma; Zora Modrusan; Sarah Kummerfeld; Rohit Reja; Yafei Zhang; Vicky Cho; Daniel Andrews; Lucy X. Morris; Christopher C. Goodnow; Edward M. Bertram; Vishva Dixit
Analytical and Bioanalytical Chemistry, ISSN: 16182650 16182642
Suk-Joon Hyung; Dongwei Li; Neelima Koppada; Surinder Kaur; Ola Saad