Publications
Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.
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mAbs, ISSN: 19420870 19420862
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Cyclodextrin Reduces Intravenous Toxicity of a Model Compound
Journal of Pharmaceutical Sciences, ISSN: 00223549
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Cancer Cell, ISSN: 18783686 15356108
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Durability of Diabetic Retinopathy Improvement with As-Needed Ranibizumab: Open-Label Extension of RIDE and RISE Studies
Ophthalmology, ISSN: 01616420
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Journal of Molecular Biology, ISSN: 10898638 00222836
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Integrin Signaling in Cancer: Mechanotransduction, Stemness, Epithelial Plasticity, and Therapeutic Resistance
Cancer Cell, ISSN: 15356108
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Interaction of cell culture process parameters for modulating mAb afucosylation
Biotechnology and Bioengineering, ISSN: 00063592
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Quantifying the vial capping process: Residual seal force and container closure integrity
PDA Journal of Pharmaceutical Science and Technology, ISSN: 10797440
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Quantitative X-Ray Microcomputed Tomography Assessment of Internal Tablet Defects
Journal of Pharmaceutical Sciences, ISSN: 00223549
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Annals of the Rheumatic Diseases, ISSN: 14682060 00034967
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Simulating an Anti–Vascular Endothelial Growth Factor Switch in Neovascular Age-Related Macular Degeneration: A HARBOR Subanalysis
Ophthalmology, ISSN: 01616420
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Split-cakes, still delicious
PDA Journal of Pharmaceutical Science and Technology, ISSN: 10797440
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Unexpected equivalent potency of a constrained chromene enantiomeric pair rationalized by co-crystal structures in complex with estrogen receptor alpha
Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X
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Durable remissions with obinutuzumab-based chemoimmunotherapy: Long-term follow-up of the phase 1b GALTON trial in CLL
Blood, ISSN: 00064971
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EMBO Journal, ISSN: 14602075 02614189
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Characterizing and enhancing virus removal by protein A chromatography
Biotechnology and Bioengineering, ISSN: 00063592
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Cambridge Quarterly of Healthcare Ethics, ISSN: 14692147 09631801
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Journal of Proteome Research, ISSN: 15353907 15353893
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Journal of Biological Chemistry, ISSN: 1083351X 00219258
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American Journal of Physiology - Renal Physiology, ISSN: 15221466 03636127
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Journal of Allergy and Clinical Immunology, ISSN: 10976825 00916749
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Quantitative neuroimaging measures of myelin in the healthy brain and in multiple sclerosis
Human Brain Mapping, ISSN: 10659471
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The Escherichia coli -barrel assembly machinery is sensitized to perturbations under high membrane fluidity
Journal of Bacteriology, ISSN: 00219193
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Tumor-Infiltrating Lymphocytes in Patients Receiving Trastuzumab/Pertuzumab-Based Chemotherapy: A TRYPHAENA Substudy
Journal of the National Cancer Institute,
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Biotechnology Progress, ISSN: 15206033 87567938
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Investigation of the absolute bioavailability and human mass balance of navoximod, a novel IDO1 inhibitor
British Journal of Clinical Pharmacology, ISSN: 03065251
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Production, characterization, and in vivo half-life extension of polymeric IgA molecules in mice
mAbs, ISSN: 19420862
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Protein conjugates and fusion proteins as ocular therapeutics
Drug Discovery Today, ISSN: 13596446
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Safety analysis of rFVIIa with emicizumab dosing in congenital hemophilia A with inhibitors: Experience from the HAVEN clinical program
Journal of Thrombosis and Haemostasis, ISSN: 15387933
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Methods in Pharmacology and Toxicology, ISSN: 19406053 15572153
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Enantioselective synthesis of GNE-6688, a potent and selective inhibitor of interleukin-2 inducible T-cell kinase (ITK)
Tetrahedron Letters, ISSN: 00404039
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Bioinformatics, ISSN: 14602059 13674803
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A flexible and scalable high-throughput platform for recombinant membrane protein production
Methods in Molecular Biology, ISSN: 10643745
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Autophagy of Sensory Neurons in the Trigeminal and Dorsal Root Ganglia of Cynomolgus Monkeys (Macaca fascicularis)
Toxicologic Pathology, ISSN: 01926233
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Bromodomains: a new target class for drug development
Nature Reviews Drug Discovery, ISSN: 14741776
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Design of a brain-penetrant CDK4/6 inhibitor for glioblastoma
Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X
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Discovery of a C-8 hydroxychromene as a potent degrader of estrogen receptor alpha with improved rat oral exposure over GDC-0927
Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X
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High-throughput protein analysis using negative stain electron microscopy and 2D classification
Methods in Molecular Biology, ISSN: 10643745
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Identification and characterization of an octameric PEG-protein conjugate system for intravitreal long-acting delivery to the back of the eye
PLoS ONE,
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Impact of Surfactant and Surfactant-Polymer Interaction on Desupersaturation of Clotrimazole
Journal of Pharmaceutical Sciences, ISSN: 00223549
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Semiautomated small-scale purification method for high-throughput expression analysis of recombinant proteins
Methods in Molecular Biology, ISSN: 10643745
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Time-to-Event Modeling of Peripheral Neuropathy: Platform Analysis of Eight Valine-Citrulline-Monomethylauristatin E Antibody–Drug Conjugates
CPT: Pharmacometrics and Systems Pharmacology,
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Journal of Clinical Oncology, ISSN: 15277755 0732183X
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Science, ISSN: 10959203 00368075
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A Rapid High-Sensitivity Reversed -Phase Ultra High Performance Liquid Chromatography Mass Spectrometry Method for Assessing Polysorbate 20 Degradation in Protein Therapeutics
Journal of Pharmaceutical Sciences, ISSN: 00223549
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mAbs, ISSN: 19420870 19420862
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Cellular mechanisms of etrolizumab treatment in inflammatory bowel disease
Frontiers in Pharmacology,
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Haemophilia, ISSN: 13652516 13518216
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Current Medical Research and Opinion, ISSN: 14734877 03007995
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Trends in Cancer, ISSN: 24058033
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