Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 251 - 300 OF 11911 RESULTS

Durable remissions with obinutuzumab-based chemoimmunotherapy: Long-term follow-up of the phase 1b GALTON trial in CLL
Blood, ISSN: 00064971
Jennifer R. Brown; Susan O'Brien; C. Daniel Kingsley; Herbert Eradat; John M. Pagel; Jamie Hirata; Tammy McIver; Rodica Morariu-Zamfir; Thomas J. Kipps
EMBO Journal, ISSN: 14602075 02614189
David Castillo-Azofeifa; Elena N Fazio; Roy Nattiv; Hayley J Good; Tomas Wald; Michael A Pest; Frederic De Sauvage; Ophir D Klein; Samuel Asfaha
Characterizing and enhancing virus removal by protein A chromatography
Biotechnology and Bioengineering, ISSN: 00063592
Chinwei Pan; Alejandro Becerra-Arteaga; Ben Tran; Michael Chinn; Hua Wang; Qi Chen; Herbert Lutz; Min Zhang
Cambridge Quarterly of Healthcare Ethics, ISSN: 14692147 09631801
Ariella Kelman; Anna Kang; Brian Crawford
Journal of Proteome Research, ISSN: 15353907 15353893
Veronica Anania; Kebing Yu; Francesco Pingitore; Qingling Li; Christopher M. Rose; Peter Liu; Wendy Sandoval; Ann E. Herman; Jennie Lill; Rod Mathews
Journal of Biological Chemistry, ISSN: 1083351X 00219258
Aaron Nile; Rami Hannoush
American Journal of Physiology - Renal Physiology, ISSN: 15221466 03636127
Luke Xie; Georgios Koukos; Kai Barck; Oded Foreman; Wyne P. Lee; Bob Brendza; Jeff Eastham; Brent S. McKenzie; Andy Peterson; Rick Carano
Journal of Allergy and Clinical Immunology, ISSN: 10976825 00916749
Nicola A. Hanania; Bradley E. Chipps; Noelle Griffin; Bongin Yoo; Ahmar Iqbal; Thomas B. Casale
Quantitative neuroimaging measures of myelin in the healthy brain and in multiple sclerosis
Human Brain Mapping, ISSN: 10659471
Jonathan O'Muircheartaigh; Irene Vavasour; Emil Ljungberg; David K. B. Li; Alexander Rauscher; Victoria Levesque; Hideki Garren; David Clayton; Roger Tam; Traboulsee; Shannon Kolind
The Escherichia coli -barrel assembly machinery is sensitized to perturbations under high membrane fluidity
Journal of Bacteriology, ISSN: 00219193
Kelly M. Storek; Rajesh Vij; Dawei Sun; Peter Smith; James T. Koerber; Steven T. Rutherford
Tumor-Infiltrating Lymphocytes in Patients Receiving Trastuzumab/Pertuzumab-Based Chemotherapy: A TRYPHAENA Substudy
Journal of the National Cancer Institute,
Michail Ignatiadis; Gert G.G.M. Van Den Eynden; Salgado Roberto; Marco Fornili; Yacine Bareche; Christine Desmedt; Rothé; Maetens; David Venet; Esther Holgado; Virginia McNally; Astrid Kiermaier; Heidi Savage; Tim Wilson; Javier Cortes; Andreas Schneeweiss; Karen Willard-Gallo; Elia Biganzoli; Christos Sotiriou
Biotechnology Progress, ISSN: 15206033 87567938
Tomofumi Tadauchi; Cynthia Lam; Laura Liu; Yizhou Zhou; Danming Tang; Salina Louie; Brad Snedecor; Shahram Misaghi
Investigation of the absolute bioavailability and human mass balance of navoximod, a novel IDO1 inhibitor
British Journal of Clinical Pharmacology, ISSN: 03065251
Shuguang Ma; Julia Suchomel; Evelyn Yanez; Edward Yost; Xiaorong Liang; Rui Zhu; Hoa Le; Nicholas Siebers; Lori Joas; Roland Morley; Stephanie Royer Joo; Andrea Pirzkall; Laurent Salphati; Joseph A. Ware; Kari M. Morrissey
Production, characterization, and in vivo half-life extension of polymeric IgA molecules in mice
mAbs, ISSN: 19420862
Twyla Lombana; Sharmila Rajan; Julie A. Zorn; Danielle Mandikian; Eugene C. Chen; Alberto Estevez; Victor Yip; Daniel D. Bravo; Wilson Phung; Farzam Farahi; Sharon Viajar; Sophia Lee; Avinash Gill; Wendy Sandoval; Jianyong Wang; Claudio Ciferri; Andy Boswell; Marissa Matsumoto; Christoph Spiess
Protein conjugates and fusion proteins as ocular therapeutics
Drug Discovery Today, ISSN: 13596446
Shrenik C. Mehta; Robert Kelley; Devin Tesar
Safety analysis of rFVIIa with emicizumab dosing in congenital hemophilia A with inhibitors: Experience from the HAVEN clinical program
Journal of Thrombosis and Haemostasis, ISSN: 15387933
Gallia Levy; Elina Asikanius; Peter Kuebler; Soraya Benchikh El Fegoun; Sille Esbjerg; Stephanie Seremetis
Methods in Pharmacology and Toxicology, ISSN: 19406053 15572153
Jake Luoma; Graham Magill; Lokesh Kumar; Zakaria Yusoff
Enantioselective synthesis of GNE-6688, a potent and selective inhibitor of interleukin-2 inducible T-cell kinase (ITK)
Tetrahedron Letters, ISSN: 00404039
Jared Moore; Kevin Lau; Xiaofeng Xu; Yamin Zhang; Jason Burch
Bioinformatics, ISSN: 14602059 13674803
Kevin Y.X. Wang; Alexander M. Menzies; Ines P. Silva; James S. Wilmott; Yibing Yan; Matthew Wongchenko; Richard F. Kefford; Richard A. Scolyer; Georgina V. Long; Garth Tarr; Samuel Mueller; Jean Y.H. Yang
A flexible and scalable high-throughput platform for recombinant membrane protein production
Methods in Molecular Biology, ISSN: 10643745
Hui Xu; Thomas Clairfeuille; Christine C. Jao; Hoangdung Ho; Zach Sweeney; Jian Payandeh; Chris Koth
Autophagy of Sensory Neurons in the Trigeminal and Dorsal Root Ganglia of Cynomolgus Monkeys (Macaca fascicularis)
Toxicologic Pathology, ISSN: 01926233
Mark T. Butt; Reina Fuji; Mike Reichelt; Alok K. Sharma; Sarah Cramer
Bromodomains: a new target class for drug development
Nature Reviews Drug Discovery, ISSN: 14741776
Andrea Cochran; Andrew R. Conery; Robert J. Sims
Design of a brain-penetrant CDK4/6 inhibitor for glioblastoma
Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X
Sarah M. Bronner; Karl A. Merrick; Jeremy Murray; Laurent Salphati; John Moffat; Jodie Pang; Christopher Sneeringer; Nick Dompe; Patrick Cyr; Hans Purkey; Gladys de Leon Boenig; Jun Li; Aleksandr Kolesnikov; Larouche-Gauthier; Kwong Wah Lai; Xiaoli Shen; Samuel Aubert-Nicol; Yi-Chen Chen; Jonathan Cheong; James Crawford; Marc Hafner; Pouyan Haghshenas; Araz Jakalian; Jean-Philippe Leclerc; Ngiap-Kie Lim; Thomas O'Brien; Emile Plise; Shalan; Claudio Sturino; John Wai; Yang Xiao; Peter Yin; Zhao; Stephen Gould; Alan Olivero; Tim Heffron
Discovery of a C-8 hydroxychromene as a potent degrader of estrogen receptor alpha with improved rat oral exposure over GDC-0927
Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X
Sharada Labadie; Jun Li; Robert Blake; Jae H. Chang; Simon Goodacre; Steven J. Hartman; Weiling Liang; James Kiefer; Tracy Kleinheinz; Tommy Lai; Jiangpeng Liao; Dan Ortwine; Vidhi Mody; Nicholas C. Ray; Fabien Roussel; Maia Vinogradova; Siew Kuen Yeap; Birong Zhang; Xiaoping Zheng; Jason Zbieg; Jun Liang; Gina Wang
High-throughput protein analysis using negative stain electron microscopy and 2D classification
Methods in Molecular Biology, ISSN: 10643745
Chris Arthur; Claudio Ciferri
Identification and characterization of an octameric PEG-protein conjugate system for intravitreal long-acting delivery to the back of the eye
PLoS ONE,
Whitney Shatz; Phil Hass; Nikhil Peer; Maciej Paluch; Craig Blanchette; Guanghui Han; Wendy Sandoval; Ashley Morando; Kelly Loyet; Vladimir Bantseev; Helen Booler; Susan Crowell; Amrita Kamath; Justin Scheer; Robert Kelley
Impact of Surfactant and Surfactant-Polymer Interaction on Desupersaturation of Clotrimazole
Journal of Pharmaceutical Sciences, ISSN: 00223549
Wei Zhang; Siddhi S. Hate; David J. Russell; Hao Helen Hou; Karthik Nagapudi
Semiautomated small-scale purification method for high-throughput expression analysis of recombinant proteins
Methods in Molecular Biology, ISSN: 10643745
Edward Kraft; Yvonne Franke; Katharine Heeringa; Stephanie Shriver; Inna Zilberleyb; Christine Kugel; Trisha Dela Vega; Athena Wong; Bobby Brillantes; Claudio Ciferri; George Dutina; Grace Lee; Isabelle Lehoux; Zhong Rong Li; Lee Lior-Hoffmann; Jiyoung Hwang; Chris Lonergan; Lynn Martin; Kyle Mortara; Lananh Nguyen; Jian Payandeh; Andrew Perez; Jun Sampang; Lovejit Singh; Kurt Schroeder; Christine Tam; Shu Ti; Ye Naing Win; Krista Bowman
Time-to-Event Modeling of Peripheral Neuropathy: Platform Analysis of Eight Valine-Citrulline-Monomethylauristatin E Antibody–Drug Conjugates
CPT: Pharmacometrics and Systems Pharmacology,
Kagedal; Divya Samineni; Gillespie; Dan Lu; Bernard Fine; Sandhya Girish; Chunze Li; Jin Y. Jin
Journal of Experimental Medicine, ISSN: 15409538 00221007
Quang T. Le; Jonathan J. Lyons; Andrea N. Naranjo; Ana Olivera; Bob Lazarus; Dean D. Metcalfe; Joshua D. Milner; Lawrence B. Schwartz
Journal of Pharmacology and Experimental Therapeutics, ISSN: 15210103 00223565
Nicholas Steven Jones; Helen Winter; Tamiko R. Katsumoto; Marilyn Florero; Elaine Murray; Helen Walker; Nand Singh; Leslie Chinn
Drug Metabolism and Disposition, ISSN: 1521009X 00909556
Donglu Zhang; Aimee Fourie-O'Donohue; Peter Dragovich; Thomas Pillow; Jack D. Sadowsky; Kathy Kozak; Robert T. Cass; Liling Liu; Yuzhong Deng; Yichin Liu; Marcel Hop; Cyrus Khojasteh
Journal of Comparative Effectiveness Research, ISSN: 20426313 20426305
Tricia Luhn; Stephen Y. Chui; Angela Fu-Chi Hsieh; Jingbo Yi; Almut Mecke; Preeti S. Bajaj; Waseem Hasnain; Adeline Falgas; Thanh G.N. Ton; Allison W. Kurian
Drug Metabolism and Disposition, ISSN: 1521009X 00909556
Donglu Zhang; Peter Dragovich; Shang-Fan Yu; Yong Ma; Thomas Pillow; Jack D. Sadowsky; Dian Su; Wei Wang; Andy Polson; Cyrus Khojasteh; Marcel Hop
PLoS Biology, ISSN: 15457885 15449173
Vande Walle; Irma Stowe; Pavel Šácha; Bettina L. Lee; Dieter Demon; Amelie Fossoul; Filip Van Hauwermeiren; Pedro H.V. Saavedra; Petr Šimon; Vladimír Šubrt; Libor Kostka; Craig Stivala; Victoria C. Pham; Steven Staben; Sayumi Yamazoe; Jan Konvalinka; Nobuhiko Kayagaki; Mohamed Lamkanfi
Journal of Biological Chemistry, ISSN: 1083351X 00219258
Suman Rao; Guangyan Du; Marc Hafner; Kartik Subramanian; Peter K. Sorger; Nathanael S. Gray
A Quantitative Systems Pharmacology Consortium Approach to Managing Immunogenicity of Therapeutic Proteins
CPT: Pharmacometrics and Systems Pharmacology,
Andrzej M. Kierzek; Timothy P. Hickling; Isabel Figueroa; Kalvass; Marjoleen JMA Nijsen; Krithika Mohan; Geertruida M. Veldman; Akihiro Yamada; Hiroyuki Sayama; Sachiko Yokoo; Abhishek Gulati; Renu S. Dhanikula; Jochem Gokemeijer; Tarek A. Leil; Craig J. Thalhauser; Mario Giorgi; Maciej J. Swat; Vijayalakshmi Chelliah; Ben G. Small; Neil Benson; Michael Walker; Kapil Gadkar; Valerie Quarmby; Rong Deng; Andrea Ferrante; Gemma L. Dickinson; Jan-Stefan Van Der Walt; Lian Zhou; Xiaoying Chen; Hannah M. Jones; Jatin Narula; Sophie Tourdot; Thierry Lavé; Ribba; Van Der Graaf
Cell and Tissue Research, ISSN: 14320878 0302766X
Webster; Sara F. Santagostino; Oded Foreman
Clinical Pharmacology and Therapeutics, ISSN: 15326535 00099236
Nicholas Steven Jones; Kenta Yoshida; Laurent Salphati; Jane Kenny; Matthew Durk; Leslie Chinn
Current Medical Research and Opinion, ISSN: 14734877 03007995
Patrick W. Sullivan; Qianyi Li; S. Pinar Bilir; Joseph Dang; Abhishek Kavati; Ming Yang; Yamina Rajput
De Novo Versus Recurrent HER2-Positive Metastatic Breast Cancer: Patient Characteristics, Treatment, and Survival from the SystHERs Registry
Oncologist, ISSN: 10837159
Debasish Tripathy; Adam Brufsky; Melody A. Cobleigh; Mohammad Jahanzeb; Peter A. Kaufman; Ginny Mason; O'Shaughnessy; Hope S. Rugo; Sandra M. Swain; Denise A. Yardley; Laura Chu; Haocheng Li; Vince Antao; Sara A. Hurvitz
ACS Symposium Series, ISSN: 19475918 00976156
James Crawford; Haiming Zhang
ACS Symposium Series, ISSN: 19475918 00976156
Stefan Koenig; Thomas Pillow
Drug Metabolism and Disposition, ISSN: 1521009X 00909556
Donglu Zhang; Marcel Hop; Gabriela Patilea-Vrana; Gautham Gampa; Herana Kamal Seneviratne; Jashvant D. Unadkat; Jane Kenny; Karthik Nagapudi; Li Di; Lian Zhou; Mark Zak; Matthew Wright; Namandjé N. Bumpus; Richard Zang; Xingrong Liu; Yurong Lai; Cyrus Khojasteh
Efficacy, Safety, and Tolerability of Pertuzumab, Trastuzumab, and Docetaxel for Patients with Early or Locally Advanced ERBB2-Positive Breast Cancer in Asia: The PEONY Phase 3 Randomized Clinical Trial
JAMA Oncology, ISSN: 23742437
Zhimin Shao; Da Pang; Hongjian Yang; Wei Li; Shusen Wang; Shude Cui; Ning Liao; Yongsheng Wang; Chuan Wang; Yuan-Ching Chang; Hwei-Chung Wang; Seok Yun Kang; Jae Hong Seo; Kunwei Shen; Suphawat Laohawiriyakamol; Zefei Jiang; Junjie Li; Julian Zhou; Betsy Althaus; Yixiang Mao; Jennifer Eng-Wong
Leukemia and Lymphoma, ISSN: 10292403 10428194
Rong Deng; Leonid Gibiansky; Tong Lu; Xiaobin Li; Dan Lu; Chunze Li; Sandhya Girish; Jue Wang; Michelle Boyer; Noopur Shankar; Kathryn Humphrey; Kevin J. Freise; Ahmed Hamed Salem; John F. Seymour; Kater; Dale Miles
Fibroblastic reticular cells enhance T cell metabolism and survival via epigenetic remodeling
Nature Immunology, ISSN: 15292908
Flavian D. Brown; Debattama R. Sen; Martin LaFleur; Jernej Godec; Veronika Lukacs-Kornek; Frank A Schildberg; Hye-Jung Kim; Kathleen B. Yates; Ricoult; Kevin Bi; Justin D. Trombley; Varun N. Kapoor; Illana A. Stanley; Viviana Cremasco; Nika N. Danial; Brendan D. Manning; Arlene H. Sharpe; W. Nicholas Haining; Shannon Turley
ACS Symposium Series, ISSN: 19475918 00976156
Remy Angelaud; Steven Staben; Tim Heffron; Andreas M. Schuster; Frederic St-Jean
Bioconjugate Chemistry, ISSN: 15204812 10431802
Amin Famili; Susan Crowell; Kelly Loyet; Danielle Mandikian; Andy Boswell; David Cain; Joyce Chan; Laetitia Comps-Agrar; Amrita Kamath; Karthik Rajagopal
ACS Sustainable Chemistry and Engineering, ISSN: 21680485
Benjamin F. Mann; Holst M. Halsey; Mohammad Al-Sayah; Archana Kumar; Tina Nguyen; Kevin Crossley; Preeti Sejwal; Yuwen Wang; Heewon Lee; Dana Ostrowski; Alan Katz; Frank Bernardoni; Simon Hamilton; Erik L. Regalado