Scientists / Publications

Publications

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DISPLAYING 251 - 300 OF 15667 RESULTS

Brain Chimeroids reveal individual susceptibility to neurotoxic triggers
Nature, ISSN: 00280836
Noelia Antón-Bolaños; Irene Faravelli; Tyler Faits; Sophia Andreadis; Rahel Kastli; Sebastiano Trattaro; Xian Adiconis; Anqi Wei; Abhishek Sampath Kumar; Daniela J. Di Bella; Matthew Tegtmeyer; Ralda Nehme; Joshua Z. Levin; Aviv Regev; Paola Arlotta
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Evaluating the Improvement of Blend Potency Measurements in the Feed Frame of a Rotary Tablet Press Using Combined NIR and Raman Spectroscopy
Analytical Chemistry, ISSN: 00032700
Alexander De Man; Lisa De Souter; Zhenqi Shi; Chen Mao; Thomas De Beer
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Improving laboratory animal genetic reporting: LAG-R guidelines
Nature Communications,
Lydia Teboul; James Amos-Landgraf; Fernando J. Benavides; Marie-Christine Birling; Steve D M Brown; Elizabeth Bryda; Rosie Bunton-Stasyshyn; Hsian-Jean Chin; Martina Crispo; Fabien Delerue; Michael Dobbie; Craig L. Franklin; Ernst-Martin Fuchtbauer; Xiang Gao; Christelle Golzio; Rebecca Haffner; Yann Hérault; Martin Hrabe de Angelis; Kevin C Kent Lloyd; Terry R. Magnuson; Lluis Montoliu; Stephen A. Murray; Ki-Hoan Nam; Lauryl M J Nutter; Eric Pailhoux; Fernando Pardo Manuel de Villena; Kevin Peterson; Laura Reinholdt; Radislav Sedlacek; Je Kyung Seong; Toshihiko Shiroishi; Cynthia L. Smith; Toru Takeo; Louise Tinsley; Jean-Luc Vilotte; Søren Warming; Sara Wells; C Bruce Whitelaw; Atsushi Yoshiki; Guillaume Pavlovic
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IMpassion132 double-blind randomised phase III trial of chemotherapy with or without atezolizumab for early relapsing unresectable locally advanced or metastatic triple-negative breast cancer
Annals of Oncology, ISSN: 09237534
Rebecca Dent; Fabrice Andre; Anthony Gonçalves; Miguel Martin; Schmid; Schutz; Sherko Kuemmel; Sandra M. Swain; Bilici; Loirat; Villalobos Valencia; Seock-Ah Im; Yeon Hee Park; De Laurentis; Colleoni; Guarneri; Giampaolo Bianchini; Li; Kirchmayer Machackova; Mouta; Regula Deurloo; Xinxin Gan; Fan; Aruna Mani; Swat; Javier Cortés
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Survey of Pharmaceutical Industry’s Best Practices around In Vitro Transporter Assessment and Implications for Drug Development: Considerations from the International Consortium for Innovation and Quality for Pharmaceutical Development Transporter Working Group
Drug Metabolism and Disposition, ISSN: 00909556
Helen E. Rollison; Pallabi Mitra; Hugues Chanteux; Zhizhou Fang; Xiaomin Liang; Seong Hee Park; Chester L. Costales; Imad Hanna; Nilay Thakkar; James Vergis; Daniel A.J. Bow; Kathleen M. Hillgren; Jochen Brumm; Xiaoyan Chu; Cornelis E. Hop; Yurong Lai; Cindy Yanfei Li; Kelly M. Mahar; Laurent Salphati; Rucha Sane; Shen; Kunal S. Taskar; Mitchell E. Taub; Kimio Tohyama; Christine Xu; Fenner
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Promoting diversity in clinical trials: insights from planning the ALUMNI AD study in historically underrepresented US populations with early symptomatic Alzheimer's disease
EClinicalMedicine,
Wise-Brown; Sharon A. Brangman; J. Neil Henderson; Monica Willis-Parker; Stephanie Monroe; Mintzer; Michael Grundman; Janice Smith; Rachelle S. Doody; Helen Lin; Beverly Assman; Gregory A. Rippon; Rozanno Gonzales; Sheila Seleri Assunção
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Generality of Enhancing the Dissolution Rates of Free Acid Amorphous Solid Dispersions by the Incorporation of Sodium Hydroxide
Molecular Pharmaceutics, ISSN: 15438384
Helen J. Zhang; Cheng W. Chiang; Tristan Maschmeyer-Tombs; Breanna Conklin; José G. Napolitano; Joseph W. Lubach; Karthik Nagapudi; Chen Mao; Yinshan Chen
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Toxigenic Clostridium perfringens Isolated from At-Risk Paediatric Inflammatory Bowel Disease Patients
Journal of Crohn's and Colitis, ISSN: 18739946
James Kuo; Jasmina Uzunovic; Amanda Jacobson; Michelle Dourado; Sarah Gierke; Manohary Rajendram; Daniela Keilberg; Jordan S. Mar; Emily Stekol; Joanna Curry; Sofia Verstraete; Jessica Lund; Yuxin Liang; Fiona B Tamburini; Natalie S. Omattage; Matthieu Masureel; Steven T. Rutherford; David Hackos; Man-Wah Tan; Allyson L. Byrd; Mary E. Keir; Elizabeth Skippington; Kelly M. Storek
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Author Correction: c-Maf-dependent Treg cell control of intestinal TH17 cells and IgA establishes host–microbiota homeostasis (Nature Immunology, (2019), 20, 4, (471-481), 10.1038/s41590-019-0316-2)
Nature Immunology, ISSN: 15292908
Christian Neumann; Jonas Blume; Urmi Roy; Peggy P. Teh; Ajithkumar Vasanthakumar; Alexander Beller; Yang Liao; Frederik Heinrich; Teresita L. Arenzana; Jason A. Hackney; Celine Eidenschenk; Eric J. C. Gálvez; Christina Stehle; Gitta A. Heinz; Patrick Maschmeyer; Tom Sidwell; Yifang Hu; Derk Amsen; Chiara Romagnani; Hyun-Dong Chang; Andrey Kruglov; Mir-Farzin Mashreghi; Wei Shi; Till Strowig; Sascha Rutz; Axel Kallies; Alexander Scheffold
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Reconstitution of the alternative pathway of the complement system enables rapid delineation of the mechanism of action of novel inhibitors
Journal of Biological Chemistry, ISSN: 00219258
Andrew C. Goodrich; Norbert P. LeClair; Nita Shillova; William D. Morton; Arthur J. Wittwer; Kelly M. Loyet; Rami N. Hannoush
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Cost-effectiveness of large-panel next-generation sequencing in guiding first-line treatment decisions for patients with nonsquamous advanced non-small cell lung cancer
Journal of Managed Care and Specialty Pharmacy, ISSN: 23760540
Ibrahim Abbass; Daniel Sheinson; Anuj Shah; Adam Gondos; Sarika Ogale
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Outcomes of the EMDataResource cryo-EM Ligand Modeling Challenge
Nature Methods, ISSN: 15487091
Catherine L. Lawson; Andriy Kryshtafovych; Grigore Pintilie; Stephen K. Burley; Jiří Černý; Vincent B. Chen; Paul Emsley; Alberto Gobbi; Andrzej Joachimiak; Sigrid Noreng; Michael G. Prisant; Randy J. Read; Jane S. Richardson; Alexis Rohou; Bohdan Schneider; Benjamin D. Sellers; Chenghua Shao; Elizabeth Sourial; Chris I. Williams; Christopher J. Williams; Ying Yang; Venkat Abbaraju; Pavel V. Afonine; Matthew L. Baker; Paul S. Bond; Tom L. Blundell; Tom Burnley; Arthur Campbell; Renzhi Cao; Jianlin Cheng; Grzegorz Chojnowski; Cowtan; Frank DiMaio; Reza Esmaeeli; Nabin Giri; Helmut Grubmüller; Soon Wen Hoh; Jie Hou; Corey F. Hryc; Carola Hunte; Maxim Igaev; Agnel P. Joseph; Wei-Chun Kao; Daisuke Kihara; Dilip Kumar; Lijun Lang; Sean Lin; Sai R. Maddhuri Venkata Subramaniya; Sumit Mittal; Arup Mondal; Nigel W. Moriarty; Andrew Muenks; Garib Murshudov; Robert A. Nicholls; Mateusz Olek; Colin M. Palmer; Alberto Perez; Emmi Pohjolainen; Karunakar R. Pothula; Christopher N. Rowley; Daipayan Sarkar; Luisa U. Schäfer; Christopher J. Schlicksup; Gunnar F. Schröder; Mrinal Shekhar; Dong Si; Abhishek Singharoy; Oleg V. Sobolev; Genki Terashi; Andrea C. Vaiana; Sundeep C. Vedithi; Jacob Verburgt; Xiao Wang; Rangana Warshamanage; Martyn D. Winn; Simone Weyand; Keitaro Yamashita; Minglei Zhao; Michael F. Schmid; Helen Berman; Wah Chiu
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Matching-adjusted indirect comparison from the Lymphoma Epidemiology of Outcomes Consortium for Real World Evidence (LEO CReWE) study to a clinical trial of mosunetuzumab in relapsed or refractory follicular lymphoma
Haematologica, ISSN: 03906078
Matthew J. Maurer; Carla Casulo; Melissa C Larson; Thomas M. Habermann; Izidore S. Lossos; Yucai Wang; Loretta J. Nastoupil; Christopher Strouse; Dai Chihara; Peter Martin; Jonathon B Cohen; Wojciech Jurczak; W. Richard Burack; Jean L. Koff; Yong Mun; Anthony Masaquel; Mei Wu; Michael C. Wei; Ashwini Shewade; Jia Li; James R. Cerhan; Brian K. Link; Christopher R. Flowers
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The association of histopathologic features after neoadjuvant chemo-immunotherapy with clinical outcome: Sub-analyses from the randomized double-blinded, placebo-controlled, Phase III IMagyn050/GOG3015/ENGOT-ov39 study
Gynecologic Oncology, ISSN: 00908258
Paulette Mhawech-Fauceglia; Denis McCarthy; Akiko Tonooka; Giovanni Scambia; Yolanda Garcia; Pavel Dundr; Anne M. Mills; Kevin L. Moore; Sakiko Sanada; Leslie Bradford; Giulia Carlo Stella; Michael A. Bookman; Sudarshan K. Sharma; Frederic Selle; Luciana L. Molinero; Yvette He; Victor K. Khor; Charles N. Landen; Yvonne G. Lin
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Entrectinib in ROS1-positive advanced non-small cell lung cancer: the phase 2/3 BFAST trial
Nature Medicine, ISSN: 1546170X 10788956
Solange Peters; Shirish M. Gadgeel; Tony Mok; Ernest Nadal; Saadettin Kilickap; Aurélie Swalduz; Jacques Cadranel; Shunichi Sugawara; Chao-Hua Chiu; Chong-Jen Yu; Mor Moskovitz; Tomohiro Tanaka; Rhea Nersesian; Sarah M. Shagan; Margaret Maclennan; Michael Mathisen; Vijay Bhagawati-Prasad; Cheick Diarra; Zoe June Assaf; Venice Archer; Rafal Dziadziuszko
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Accelerated drug-resistant variant discovery with an enhanced, scalable mutagenic base editor platform
Cell Reports,
Kristel Dorighi; Anqi Zhu; Jean-Philippe Fortin; Jerry Hung-Hao Lo; Jawahar Sudhamsu; Timothy J. Wendorff; Durinck; Marinella G. Callow; Scott A. Foster; Benjamin Haley
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CRISPR activation screens identify the SWI/SNF ATPases as suppressors of ferroptosis
Cell Reports,
Kamakoti P. Bhat; Jinchu Vijay; Caroline K. Vilas; Jyoti Asundi; Jun Zou; Ted Lau; Xiaoyu Cai; Musaddeque Ahmed; Michal Kabza; Julie Weng; Jean-Philippe Fortin; Aaron T. L. Lun; Durinck; Marc Hafner; Michael Costa; Xin Ye
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Development of a First-Generation Stereocontrolled Manufacturing Process of TRPA1 Inhibitor GDC-6599
Organic Process Research and Development, ISSN: 10836160
Allen Y. Hong; Katarzyna A. Piechowicz; Jacob C. Timmerman; Haiming Zhang; Carmela Molinaro; Francis Gosselin
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Optimization of a Novel DEL Hit That Binds in the Cbl-b SH2 Domain and Blocks Substrate Binding
ACS Medicinal Chemistry Letters,
Jun Liang; Michael J. Lambrecht; Teresita L. Arenzana; Samuel Aubert-Nicol; Linda Bao; Broccatelli; Jianping Cai; Celine Eidenschenk; Christine Everett; Thomas Garner; Felix Gruber; Pouyan Haghshenas; Malcolm P. Huestis; Peter L. Hsu; Ponien Kou; Araz Jakalian; Larouche-Gauthier; Jean-Philippe Leclerc; Dennis H. Leung; Aaron Martin; Jeremy Murray; Madeleine S. Prangley; Sascha Rutz; Satoko Kakiuchi-Kiyota; Alexander Lee Satz; Nicholas J. Skelton; Micah Steffek; Daniel Stoffler; Jawahar Sudhamsu; Sophia Tan; Jian Wang; Shouliang Wang; Qiuyue Wang; Timothy J. Wendorff; Moreno Wichert; Arun Yadav; Christine Yu; Xiaojing Wang
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Publisher Correction: Anti-TIGIT antibody improves PD-L1 blockade through myeloid and Treg cells(Nature, 10.1038/s41586-024-07121-9)
Nature, ISSN: 00280836
Xiangnan Guan; Ruozhen Hu; Yoonha Choi; Shyam Srivats; Barzin Y. Nabet; John Silva; Lisa M McGinnis; Robert Hendricks; Katherine Nutsch; Karl L. Banta; Ellen Duong; Alexis D. Dunkle; Patrick Chang; Chia-Jung Han; Stephanie Mittman; Nandini Molden; Pallavi Daggumati; Wendy Connolly; Melissa L. Johnson; Rodriguez-Abreu; Byoung Chul Cho; Antoine Italiano; Ignacio Gil-Bazo; Enriqueta Felip; Ira Mellman; Sanjeev Mariathasan; David S. Shames; Raymond D. Meng; Eugene Y. Chiang; Robert J. Johnston; Namrata S. Patil
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Potency-Enhanced Peptidomimetic VHL Ligands with Improved Oral Bioavailability
Journal of Medicinal Chemistry, ISSN: 00222623
Hao Wu; Jeremy Murray; Noriko Ishisoko; Alexandra Frommlet; Gauri Deshmukh; Antonio G. DiPasquale; Melinda M. Mulvihill; Donglu Zhang; John Quinn; Robert A. Blake; Wayne J. Fairbrother; Jakob Fuhrmann
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Context-Specific Stress Causes Compartmentalized SARM1 Activation and Local Degeneration in Cortical Neurons
Journal of Neuroscience, ISSN: 02706474
Flora I. Hinz; Carmela Louise M. Villegas; Jasmine Roberts; Heming Yao; Shreya Gaddam; Anton Delwig; Samantha A. Green; Craig Fredrickson; Max Adrian; Raymond Asuncion; Tommy K. Cheung; Margaret Hayne; David Hackos; Christopher M. Rose; David Richmond; Casper C Hoogenraad
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Umpolung Flow Chemistry for the Synthesis of a 3-Oxo-3H-spiro[benzofuran-2,4′-piperidine] Building Block
Journal of Organic Chemistry, ISSN: 00223263
Matthew M. Pompeo; Sean M. Kelly; Frederic St-Jean; Thomas M. Bass; Derek M. Dalton; Daniel Zell; Chong Han; Lauren E. Sirois; Francis Gosselin
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The Exonuclease TREX1 Constitutes an Innate Immune Checkpoint Limiting cGAS/STING-Mediated Antitumor Immunity
Cancer immunology research, ISSN: 23266066
Junghyun Lim; Ryan Rodriguez; Katherine Williams; John Silva; Alan G. Gutierrez; Paul Tyler; Faezzah Baharom; Tao Sun; Eva Lin; Scott E. Martin; Brandon D. Kayser; Robert J. Johnston; Ira Mellman; Lélia Delamarre; Nathaniel West; Sören Müller; Yan Qu; Klaus D. Heger
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Challenges and gaps in immunosafety evaluation of therapeutics: An IQ DruSafe survey
Regulatory Toxicology and Pharmacology, ISSN: 10960295 02732300
Mark Collinge; Haley Neff-LaFord; Surekha Akella; Birgit Fogal; Kathryn Fraser; Jacob Jabbour; Kirsty Harper; Curtis Maier; Laurent Malherbe; Nikki Marshall; Gautham K. Rao; Kavita Raman; Hollie Skaggs; Felix Weber; Claudette L. Fuller
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Accelerated Predictive Stability Study of a Pediatric Drug Product for a Supplemental New Drug Application
AAPS PharmSciTech,
Viktoria Rakers; Jin Wang; Dawen Kou
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Clinical Value of Timely Targeted Therapy for Patients With Advanced Non–Small Cell Lung Cancer With Actionable Driver Oncogenes
Oncologist, ISSN: 10837159
Thomas Stricker; Neha Jain; Esprit Ma; Elaine B. Yu; Rongrong Wang; Robert Schuldt; Richard Price; Szado; Jesse Sussell; Sarika Ogale; Victor Lin; Arrowsmith; Slater; Daniel Vaena; Harry Staszewski; Bruno Fang; Lasika Seneviratne; Davey B Daniel
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A randomized, double-blind study of zinpentraxin alfa in patients with myelofibrosis who were previously treated with or ineligible for ruxolitinib: stage 2 of a phase II trial
Haematologica, ISSN: 03906078
Srdan Verstovsek; Moshe Talpaz; Martha Wadleigh; Alessandro Isidori; Peter te Boekhorst; Michael Savona; Prithviraj Bose; Olga Pozdnyakova; Ruben Mesa; Tarec C. El-Galaly; Jennifer O’Sullivan; Katia Gamel; Higgins; Sudhakar Katakam; Boyan Todorov; Kerstin Trunzer; Claire N. Harrison
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Impact of P-gp inhibition on systemic exposure of pralsetinib and dosing considerations
Clinical and Translational Science, ISSN: 17528054
Julia Suchomel; Priya Agarwal; Doreen Anders; Kevin Hughes; Yang Tang; Rucha Sane; Astrid Scalori; Sunil Sharma; Sravanthi Cheeti
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Optimizing Messenger RNA Analysis Using Ultra-Wide Pore Size Exclusion Chromatography Columns
International Journal of Molecular Sciences, ISSN: 16616596
Valentina D'Atri; Honorine Lardeux; Alexandre Goyon; Mateusz Imiołek; Szabolcs Fekete; Matthew A Lauber; Kelly Zhang; Davy Guillarme
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HER2 Gene Expression Levels Are Predictive and Prognostic in Patients with Metastatic Colorectal Cancer Enrolled in CALGB/SWOG 80405
Journal of Clinical Oncology, ISSN: 0732183X
Francesca Battaglin; Fang-Shu Ou; Xueping Qu; Hochster; Donna Niedzwiecki; Richard M. Goldberg; Robert J. Mayer; Karam Ashouri; Tyler J. Zemla; Charles D. Blanke; Alan P. Venook; Omar Kabbarah; Heinz-Josef Lenz; Federico Innocenti
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Quantitative analysis of bone marrow fibrosis highlights heterogeneity in myelofibrosis and augments histological assessment: An Insight from a phase II clinical study of zinpentraxin alfa
HemaSphere,
Hosuk Ryou; Korsuk Sirinukunwattana; Ruby Wood; Alan Aberdeen; Jens Rittscher; Olga Weinberg; Robert P. Hasserjian; Olga Pozdnyakova; Franklin V. Peale Jr.; Higgins; Pontus Lundberg; Kerstin Trunzer; Claire N. Harrison; Daniel Royston
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Population pharmacokinetics and CD20 binding dynamics for mosunetuzumab in relapsed/refractory B-cell non-Hodgkin lymphoma
Clinical and Translational Science, ISSN: 17528054
Brendan C. Bender; Chi-Chung Li; Mathilde Marchand; Turner; Feifei Li; Shweta Vadhavkar; Wang; Rong Deng; James Lu; Jin Jin; Chunze Li; Shen Yin; Michael C. Wei; Pascal Chanu
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Aqueous humour interleukin-6 and vision outcomes with anti-vascular endothelial growth factor therapy
Eye,
Yasir J. Sepah; Diana V. Do; Marina Mesquida; Bann-Mo Day; Steven Blotner; Rubbia Afridi; Muhammad Sohail Halim; Kyu Hong; Eric Wakshull; Sascha Fauser; Ivaylo Stoilov; Quan Dong Nguyen
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Implementation of a Three-Way Comparability Assessment for a Bioanalytical Anti-Drug Antibody Method
AAPS Journal,
Rosanna S. Kwok; Ihsan Nijem; Ann Brady; Robert Hendricks
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Adaptive and Innate Immunity Are Key Drivers of Age at Onset of Multiple Sclerosis
Neurology: Genetics,
Elina Misicka; Yunfeng Huang; Stephanie J. Loomis; Nilanjana Sadhu; Fisher; Arie R. Gafson; Heiko Runz; Ellen Tsai; Xiaoming Jia; Ann E. Herman; Paola G. Bronson; Tushar Bhangale; Farren B. Briggs
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Molecular underpinnings of dedifferentiation and aggressiveness in chromophobe renal cell carcinoma
JCI insight,
Payal Kapur; Hua Zhong; Daniel Le; Ratna Mukhopadhyay; Jeffrey Miyata; Deyssy Carrillo; Dinesh Rakheja; Satwik Rajaram; Durinck; Zora Modrusan; James Brugarolas
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The inactivation of tolC sensitizes Escherichia coli to perturbations in lipopolysaccharide transport
iScience,
Shawna Zhu; Mary Kate Alexander; Telmo O. Paiva; Kenneth Rachwalski; Anh Miu; Yiming Xu; Vishal A. Verma; Mike Reichelt; Yves F. Dufrêne; Eric D. Brown; Georgina Cox
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Using the Dynamic Well-Stirred Model to Extrapolate Hepatic Clearance of Organic Anion-Transporting Polypeptide Transporter Substrates without Assuming Albumin-Mediated Hepatic Drug Uptake
Drug Metabolism and Disposition,
Zhengyin Yan; Li Ma; Nicky Hwang; Julie Huang; Jane R. Kenny; Cornelis E. Hop
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N4BP1 coordinates ubiquitin-dependent crosstalk within the IκB kinase family to limit Toll-like receptor signaling and inflammation
Immunity, ISSN: 10747613
Alexander D. Gitlin; Maltzman; Yuzuka Kanno; Klaus D. Heger; Rohit Reja; Alexander F Schubert; Linsey J. Wierciszewski; Homer Pantua; Sharookh B. Kapadia; Seth F. Harris; Webster; Kim Newton; Vishva M. Dixit
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Human Pharmacokinetic and CYP3A DDI Prediction of GDC-2394 using PBPK Modeling and Biomarker Assessment
Drug Metabolism and Disposition, ISSN: 00909556
Jesse Yu; Fei Tang; Fang Ma; Susan C. Wong; Jing Wang; Justin Ly; Liuxi Chen; Jialin Mao
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An Integrated Hepatocyte Stability Assay for Simultaneous Metabolic Stability Assessment and Metabolite Profiling
Drug Metabolism and Disposition, ISSN: 1521009X 00909556
Christian Leung; Joyce Liu; Katherine Cunico; Kevin Johnson; Zhengyin Yan; Jingwei Cai
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A Minimal PBPK/PD Model with Expansion-Enhanced Target-Mediated Drug Disposition to Support a First-in-Human Clinical Study Design for a FLT3L-Fc Molecule
Pharmaceutics,
Iraj Hosseini; Brett Fleisher; Jennifer A. Getz; Jérémie Decalf; Mandy Kwong; Meric A. Ovacik; Travis W. Bainbridge; Christine Moussion; Gautham K. Rao; Kapil Gadkar; Amrita Kamath; Ramanujan
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Alternative Splicing Is a Major Factor Shaping Transcriptome Diversity in Mild and Severe Chronic Obstructive Pulmonary Disease
American Journal of Respiratory Cell and Molecular Biology,
Dmitry Khalenkow; Brandsma; Timens; David F. Choy; Michele A. Grimbaldeston; Carrie M. Rosenberger; Dirk-Jan Slebos; Kerstjens; Alen Faiz; Gerard H. Koppelman; Nawijn; van den Berge; Victor Guryev
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Deep Learning Approaches for Detecting of Nascent Geographic Atrophy in Age-Related Macular Degeneration
Ophthalmology Science,
Heming Yao; Zhichao Wu; Simon S. Gao; Robyn H. Guymer; Verena Steffen; Hao Chen; Mohsen Hejrati; Miao Zhang
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Graph-pMHC: graph neural network approach to MHC class II peptide presentation and antibody immunogenicity
Briefings in bioinformatics, ISSN: 14675463
William John Thrift; Jason Perera; Sivan Cohen; Nicolas Lounsbury; Hem R. Gurung; Christopher M. Rose; Jieming Chen; Suchit Jhunjhunwala; Kai Liu
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Six-year follow-up and subgroup analyses of a phase 2 trial of venetoclax for del(17p) chronic lymphocytic leukemia
Blood advances, ISSN: 24739529
Stephan Stilgenbauer; Eugen Tausch; Andrew W. Roberts; Matthew S. Davids; Barbara Eichhorst; Michael Hallek; Hillmen; Christof Schneider; Johannes Schetelig; Sebastian Böttcher; Kater; Yanwen Jiang; Michelle Boyer; Relja Popovic; Majd T. Ghanim; Michael Moran; Wendy J. Sinai; Xifeng Wang; Nabanita Mukherjee; Brenda Chyla; William G. Wierda; John F. Seymour
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TRBC1-targeting antibody–drug conjugates for the treatment of T cell cancers
Nature, ISSN: 14764687 00280836
Tushar D. Nichakawade; Jiaxin Ge; Brian J. Mog; Bum Seok Lee; Alex Pearlman; Michael S. Hwang; Sarah R. DiNapoli; Nicolas Wyhs; Nikita Marcou; Stephanie Glavaris; Maximilian F. Konig; Sandra B. Gabelli; Evangeline Watson; Cole Sterling; Nina D. Wagner-Johnston; Sima Rozati; Lode J. Swinnen; Ephraim Fuchs; Drew M. Pardoll; Kathy Gabrielson; Nickolas Papadopoulos; Chetan Bettegowda; Kenneth W. Kinzler; Shibin Zhou; Surojit Sur; Bert Vogelstein; Suman Paul
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Cullin-RING ligases employ geometrically optimized catalytic partners for substrate targeting
Molecular Cell, ISSN: 10974164 10972765
Jerry Li; Nicholas Purser; Joanna Liwocha; Daniel C. Scott; Holly A. Byers; Barbara Steigenberger; Spencer Hill; Ishita Tripathi-Giesgen; Trent Hinkle; Fynn M. Hansen; J. Rajan Prabu; Senthil K. Radhakrishnan; Donald S. Kirkpatrick; Kurt M. Reichermeier; Brenda A. Schulman; Gary Kleiger
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Genome-wide characterization of circulating metabolic biomarkers
Nature, ISSN: 14764687 00280836
Minna Karjalainen; Savita Karthikeyan; Clare Oliver-Williams; Eeva Sliz; Elias Allara; Wing Tung Fung; Praveen Surendran; Weihua Zhang; Pekka Jousilahti; Kati Kristiansson; Veikko Salomaa; Matt Goodwin; David A. Hughes; Mike Boehnke; Lilian Fernandes Silva; Xianyong Yin; Anubha Mahajan; Matt J. Neville; Natalie van Zuydam; Renée de Mutsert; Ruifang Li-Gao; Dennis Mook-Kanamori; Ayse Demirkan; Jun Liu; Raymond Noordam; Stella Trompet; Zhengming Chen; Christiana Kartsonaki; Liming Li; Kuang Lin; Fiona A. Hagenbeek; Jouke-Jan Hottenga; René Pool; M Arfan Ikram; Joyce B.J. Van Meurs; Toomas Haller; Yuri Milaneschi; Mika Kähönen; Pashupati P. Mishra; Peter K Joshi; Erin Macdonald-Dunlop; Massimo Mangino; Jonas Zierer; Ilhan E. Acar; Carel Hoyng; Yara T. E. Lechanteur; Lude Franke; Alexander Kurilshikov; Alexandra Zhernakova; Marian Beekman; Erik van den Akker; Ivana Kolcic; Ozren Polasek; Igor Rudan; Christian Gieger; Melanie Waldenberger; Folkert W Asselbergs; Caroline Hayward; Jingyuan Fu; Anneke I. den Hollander; Cristina Menni; Tim D. Spector; James F. Wilson; Terho Lehtimäki; Olli T. Raitakari; Brenda Penninx; Tõnu Esko; Robin G. Walters; J Wouter Jukema; Naveed Sattar; Mohsen Ghanbari; Ko Willems van Dijk; Fredrik Karpe; Mark I. McCarthy; Markku Laakso; Marjo-Riitta Jarvelin; Nicholas J. Timpson; Markus Perola; Jaspal S Kooner; John C Chambers; Cornelia M. van Duijn; P. Eline Slagboom; Dorret I. Boomsma; John Danesh; Mika Ala-Korpela; Adam S. Butterworth; Johannes Kettunen
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