Scientists / Publications

Publications

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DISPLAYING 4801 - 4850 OF 16681 RESULTS

Immunoaffinity LC-MS/MS to quantify a PEGylated anti-Factor D Fab biotherapeutic in cynomolgus monkey serum
Bioanalysis, ISSN: 17576199 17576180
Luna Liu; Yanqiu Liu; Lu Dai; Cinzia Stella; Morse Faria; Junlong Shao; Jamie L Hicks; Diego F. Cortes; William R. Mylott; Eric Wakshull; Surinder Kaur; Keyang Xu
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Phase i Study of DSTP3086S, an antibody-drug conjugate targeting six-transmembrane epithelial antigen of prostate 1, in metastatic castration-resistant prostate cancer
Journal of Clinical Oncology, ISSN: 15277755 0732183X
Daniel C. Danila; Russell Z. Szmulewitz; Ulka Vaishampayan; Celestia S. Higano; Ari Baron; Houston N. Gilbert; Flavia Brunstein; Marija Milojic-Blair; Wang; Omar Kabbarah; Michael Mamounas; Bernard M. Fine; Daniel Maslyar; Alexander Ungewickell; Scher
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Healthcare costs of potential glucocorticoid-associated adverse events in patients with giant cell arteritis
ClinicoEconomics and Outcomes Research, ISSN: 11786981
Jennie Best; Amanda M. Kong; David Smith; Ibrahim Abbass; Margaret Michalska
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Cisplatin Ineligibility for Patients with Metastatic Urothelial Carcinoma: A Survey of Clinical Practice Perspectives among US Oncologists
Bladder Cancer, ISSN: 23523735 23523727
Matthew D. Galsky; Esprit Ma; Bijal Shah-Manek; Rosalina Mills; Long Ha; Craig Krebsbach; Eric Blouin; Darren Tayama; Sarika Ogale
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Homogeneity in the association of body mass index with type 2 diabetes across the UK Biobank: A Mendelian randomization study
Nature Methods, ISSN: 15491676 15491277
Michael Wainberg; Anubha Mahajan; Anshul Kundaje; Mark I. McCarthy; Erik Ingelsson; Nasa Sinnott-Armstrong; Manuel Rivas
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Disposable bioreactors
Comprehensive Biotechnology,
Oosterhuis; Terry Hudson; Alberto D’Avino; Zijlstra; Ashraf Amanullah
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Process validation
Comprehensive Biotechnology,
David H. Reifsnyder; Nathan McKnight; Kelley
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Omalizumab Effectiveness by Biomarker Status in Patients with Asthma: Evidence From PROSPERO, A Prospective Real-World Study
Journal of Allergy and Clinical Immunology: In Practice, ISSN: 22132198
Thomas B. Casale; Allan T. Luskin; William W. Busse; Robert S. Zeiger; Benjamin L. Trzaskoma; Ming Yang; Noelle M. Griffin; Bradley E. Chipps
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Consistently very poorly controlled asthma is associated with greater activity and school impairment in children with severe or difficult-to-treat asthma
Journal of Allergy and Clinical Immunology: In Practice, ISSN: 22132198
Leonard B. Bacharier; Ronina A. Covar; Tmirah Haselkorn; Ahmar Iqbal; Cynthia Alvarez; David R. Mink; Hubert Chen; Robert S. Zeiger
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Change in biomarkers of type-2 inflammation following severe exacerbations of asthma
Thorax, ISSN: 14683296 00406376
Ruth Semprini; Nick Shortt; Stefan Ebmeier; Alex Semprini; Rachel Varughese; Cécile T.J. Holweg; Matthews; James Fingleton; Mark Weatherall; Beasley; Irene Braithwaite
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Advanced imaging findings in progressive solitary sclerosis: a single lesion or a global disease?
Multiple Sclerosis Journal - Experimental, Translational and Clinical, ISSN: 20552173
Lisa Eunyoung Lee; Jillian K. Chan; Emilie Nevill; Adam Soares; Irene Vavasour; Erin L MacMillan; Hideki Garren; David Clayton; B. Mark Keegan; Roger Tam; Traboulsee; Shannon Kolind; Robert L. Carruthers
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Advanced imaging findings in progressive solitary sclerosis: a single lesion or a global disease?
Multiple Sclerosis Journal - Experimental, Translational and Clinical,
Lisa Eunyoung Lee; Jillian K. Chan; Emilie Nevill; Adam Soares; Irene Vavasour; Erin L MacMillan; Hideki Garren; David Clayton; B. Mark Keegan; Roger Tam; Traboulsee; Shannon Kolind; Robert L. Carruthers
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Bioprinted liver provides early insight into the role of Kupffer cells in TGF-β1 and methotrexate-induced fibrogenesis
PLoS ONE, ISSN: 19326203
Leah M. Norona; Deborah G. Nguyen; David A. Gerber; Sharon Collins Presnell; Merrie Mosedale; Paul B. Watkins
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2019 White Paper on Recent Issues in Bioanalysis: FDA Immunogenicity Guidance, Gene Therapy, Critical Reagents, Biomarkers and Flow Cytometry Validation (Part 3-Recommendations on 2019 FDA Immunogenicity Guidance, Gene Therapy Bioanalytical Challenges, Strategies for Critical Reagent Management, Biomarker Assay Validation, Flow Cytometry Validation & CLSI H62)
Bioanalysis, ISSN: 17576199 17576180
Steven Piccoli; Devangi Mehta; Alessandra Vitaliti; John Allinson; Shashi Amur; Steven Eck; Cherie Green; Michael Hedrick; Shirley Hopper; Allena Ji; Alison Joyce; Virginia Litwin; Kevin Maher; Joel Mathews; Kun Peng; Afshin Safavi; Yow-Ming C. Wang; Yan Zhang; Lakshmi Amaravadi; Nisha Palackal; Sai Thankamony; Chris Beaver; Eris Bame; Thomas Emrich; Grimaldi; Jonathan Haulenbeek; Vellalore Kakkanaiah; David Lanham; Andrew Mayer; Paul C Trampont; Laurent Vermet; Naveen Dakappagari; Catherine Aversa Fleener; Fabio Garofolo; Cynthia Rogers; Shabnam Tangri; Yuanxin Xu; Meina Liang; Manoj Rajadhyaksha; Richards; Becky Schweighardt; Shobha Purushothama; Daniel Baltrukonis; Jochen Brumm; Elana Cherry; Jason Delcarpini; Carol Gleason; Susan Kirshner; Robert J Kubiak; Luying Pan; Michael A. Partridge; Joao Pedras-Vasconcelos; Qiang Qu; Venke Skibeli; Therese Solstad Saunders; Roland F Staack; Kay Stubenrauch; Albert Torri; Verthelyi; Haoheng Yan; Boris Gorovits; Rachel Palmer; Milton; Brian Long; Bart Corsaro; Vahid Farrokhi; Michele Fiscella; Neil Henderson; Vibha Jawa; Jim McNally; Rocio Murphy; Hanspeter Waldner; Tong-Yuan Yang
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Biotransformation and bioactivation reactions–2018 literature highlights
Drug Metabolism Reviews, ISSN: 10979883 03602532
Siamak Cyrus Khojasteh; Namandjé N. Bumpus; James P. Driscoll; Grover Paul Miller; Kaushik Mitra; Ivonne M.C.M. Rietjens; Donglu Zhang
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A Patient-Reported Outcome Instrument to Assess Symptom Burden and Predict Survival in Patients with Advanced Cancer: Flipping the Paradigm to Improve Timing of Palliative and End-of-Life Discussions and Reduce Unwanted Health Care Costs
Oncologist, ISSN: 1549490X 10837159
Stuart L. Goldberg; Dhakshila Paramanathan; Raya Khoury; Shilpen Patel; Dayo Jagun; Srikesh Arunajadai; Victoria DeVincenzo; Ruth Pe Benito; Brooke Gruman; Sukhi Kaur; Scott Paddock; Andrew D. Norden; Eric V. Schultz; John Hervey; Terrill Jordan; Andre Goy; Andrew L. Pecora
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Micro-CT imaging and structural analysis of glomeruli in a model of adriamycin-induced nephropathy
American Journal of Physiology - Renal Physiology, ISSN: 15221466 1931857X
Luke Xie; Georgios Koukos; Kai H. Barck; Oded Foreman; Wyne P. Lee; Robert Brendza; Jeffrey Eastham-Anderson; Brent Mckenzie; Andrew S. Peterson; Richard A. D. Carano
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HPLC and UHPLC for biopharmaceutical analysis
HPLC and UHPLC for Practicing Scientists,
Jennifer C. Rea; Taylor Zhang
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Magnetic resonance spectroscopy evidence for declining gliosis in MS patients treated with ocrelizumab versus interferon beta-1a
Multiple Sclerosis Journal - Experimental, Translational and Clinical, ISSN: 20552173
Erin L MacMillan; Julia J Schubert; Irene Vavasour; Roger Tam; Alexander Rauscher; Carolyn Taylor; Rick White; Hideki Garren; David Clayton; Victoria Levesque; David K. B. Li; Shannon Kolind; Traboulsee
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Poly-ICLC, a TLR3 agonist, induces transient innate immune responses in patients with treated HIV-infection: A randomized double-blinded placebo controlled trial
Frontiers in Immunology, ISSN: 16643224
Mansi Saxena; Rachel L. Sabado; Melissa La Mar; Hiroshi Mohri; Andres M. Salazar; Hanqing Dong; Joel Correa Da Rosa; Martin Markowitz; Nina Bhardwaj; Elizabeth Miller
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Real-world usage and clinical outcomes of alectinib among post-crizotinib progression anaplastic lymphoma kinase positive non-small-cell lung cancer patients in the USA
OncoTargets and Therapy, ISSN: 11786930
Marco Dacosta DiBonaventura; William B. Wong; Bijal M. Shah-Manek; Mathias Schulz
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Green Chemistry Articles of Interest to the Pharmaceutical Industry
Organic Process Research and Development, ISSN: 1520586X 10836160
Marie-Gabrielle Braun; Alba Díaz-Rodríguez; Louis Diorazio; Zhongbo Fei; Kenneth Fraunhoffer; John Hayler; Matthew Hickey; Shaun Hughes; Mark McLaws; Paul Richardson; Markus Schober; Austin G. Smith; Alan Steven; Jack A. Terrett; Timothy White; Jingjun Yin
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Changes in the Synaptic Proteome in Tauopathy and Rescue of Tau-Induced Synapse Loss by C1q Antibodies
Neuron, ISSN: 10974199 08966273
Borislav Dejanovic; Melanie A. Huntley; Ann De Mazière; William J. Meilandt; Tiffany Wu; Karpagam Srinivasan; Zhiyu Jiang; Vineela D. Gandham; Brad A. Friedman; Hai Ngu; Oded Foreman; Richard A. D. Carano; Ben Chih; Judith Klumperman; Corey Bakalarski; Jesse E. Hanson; Morgan Sheng
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The Dendritic Cell Strikes Back
Immunity, ISSN: 10974180 10747613
Christine Moussion; Ira Mellman
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Serum periostin levels in adults of Chinese descent: An observational study ACTRN12614000122651 ACTRN 11 Medical and Health Sciences 1102 Cardiorespiratory Medicine and Haematology
Allergy, Asthma and Clinical Immunology, ISSN: 17101492 17101484
Evan Tan; Rachel Varughese; Ruth Semprini; Barney Montgomery; Cecile Holweg; Julie Olsson; Caswell-Smith; James Fingleton; Mark Weatherall; Beasley; Irene Braithwaite
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ORAI1, STIM1/2, and RYR1 shape subsecond Ca 2+ microdomains upon T cell activation
Science Signaling, ISSN: 19379145 19450877
Björn-Philipp Diercks; René Werner; Paula Weidemüller; Frederik Czarniak; Lola Hernandez; Cari Lehmann; Annette Rosche; Aileen Krüger; Ulrike Kaufmann; Martin Vaeth; Antonio V. Failla; Bernd Zobiak; Farid I. Kandil; Daniel Schetelig; Alexandra Ruthenbeck; Chris Meier; Dmitri Lodygin; Alexander Flügel; Dejian Ren; Insa M.A. Wolf; Stefan Feske; Andreas H. Guse
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IFNg-induced Chemokines Are Required for CXCR3-mediated T-Cell Recruitment and Antitumor Efficacy of Anti-HER2/CD3 Bispecific Antibody
Clinical Cancer Research, ISSN: 15573265 10780432
Ji Li; Ryan Ybarra; Judy Mak; Aurelie Herault; Patricia De Almeida; Alfonso Arrazate; James Ziai; Klara Totpal; Melissa Junttila; Kevin B. Walsh; Teemu T. Junttila
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Current status and future opportunities in lung precision medicine research with a focus on biomarkers: An American Thoracic Society/National Heart, Lung, and Blood Institute Research Statement
American Journal of Respiratory and Critical Care Medicine, ISSN: 15354970 1073449X
Ann Chen Wu; James P. Kiley; Patricia J. Noel; Shashi Amur; Esteban G. Burchard; John P. Clancy; Joshua Galanter; Maki Inada; Tiffanie K. Jones; Jonathan A Kropski; James E. Loyd; Lawrence M. Nogee; Benjamin A. Raby; Angela J. Rogers; David A. Schwartz; Don D. Sin; Avrum Spira; Weiss; Lisa R. Young; Blanca E Himes
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Germline genetic polymorphisms influence tumor gene expression and immune cell infiltration
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 10916490 00278424
Yoong Wearn Lim; Haiyin Chen-Harris; Oleg Mayba; Steve Lianoglou; Arthur Wuster; Tushar Bhangale; Zia Khan; Sanjeev Mariathasan; Anneleen Daemen; Jens Reeder; Peter M. Haverty; William F. Forrest; Matthew J. Brauer; Ira Mellman; Matthew L. Albert
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CD226 regulates natural killer cell antitumor responses via phosphorylation-mediated inactivation of transcription factor FOXO1
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 10916490 00278424
Xiangnan Du; Patricia De Almeida; Nicholas A. Manieri; Denise De Almeida Nagata; Thomas D Wu; Kristin Harden Bowles; Vidhyalakshmi Arumugam; Jill Schartner; Rafael Cubas; Stephanie Mittman; Vincent Javinal; Keith R. Anderson; Søren Warming; Jane L. Grogan; Eugene Y. Chiang
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First-line atezolizumab plus chemotherapy in extensive-stage small-cell lung cancer
New England Journal of Medicine, ISSN: 15334406 00284793
Leora Horn; Mansfield; Szczȩsna; Havel; Maciej J Krzakowski; Hochmair; Huemer; György Losonczy; Melissa L. Johnson; Makoto Nishio; Martin Reck; Tony Mok; Lam; David S. Shames; Juan Liu; Beiying Ding; Ariel Lopez-Chavez; Fairooz F. Kabbinavar; Wei Lin; Alan Sandler; Stephen V. Liu
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More is not always better: hyperglutamylation leads to neurodegeneration
EMBO Journal, ISSN: 14602075 02614189
Anna Akhmanova; Casper C Hoogenraad
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Hippo pathway inhibition by blocking the YAP/TAZ–TEAD interface: a patent review
Expert Opinion on Therapeutic Patents, ISSN: 17447674 13543776
James J. Crawford; Sarah M. Bronner; Jason R. Zbieg
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Manic Fringe deficiency imposes Jagged1 addiction to intestinal tumor cells
Nature Communications, ISSN: 20411723
Erika López-Arribillaga; Verónica Rodilla; Carlota Colomer; Anna Vert; Amy Shelton; Jason H. Cheng; Bing Yan; Abel Gonzalez-Perez; Melissa Junttila; Mar Iglesias; Ferran Torres; Joan Albanell; Alberto Villanueva; Anna Bigas; Christian W. Siebel; Lluis Espinosa
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Erratum to: Classical and alternative complement activation on photoreceptor outer segments drives monocyte-dependent retinal atrophy (Scientific Reports, (2018), 8, 1, (7348), 10.1038/s41598-018-25557-8)
Scientific Reports, ISSN: 20452322
Kenneth J. Katschke Jr.; Hongkang Xi; Christian Cox; Tom Truong; Yann Malato; Wyne P. Lee; Brent Mckenzie; Rommel Arceo; Jianhua Tao; Linda Rangell; Mike Reichelt; Laurie Diehl; Justin Elstrott; Robby M. Weimer; Menno Van Lookeren Campagne
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Erratum to: Comprehensive analysis of single molecule sequencing-derived complete genome and whole transcriptome of Hyposidra talaca nuclear polyhedrosis virus (Scientific Reports, (2018), 8, 1, (8924), 10.1038/s41598-018-27084-y)
Scientific Reports, ISSN: 20452322
Thong T Nguyen; Kushal Suryamohan; Boney Kuriakose; Vasantharajan Janakiraman; Mike Reichelt; Subhra Chaudhuri; Joseph Guillory; Neethu Divakaran; Rabins; Ridhi Goel; Bhabesh Deka; Suman Sarkar; Preety Ekka; Yu-Chih Tsai; Derek Vargas; Sam Santhosh; Sangeetha Mohan; Chen-Shan Chin; Jonas Korlach; George Thomas; Azariah Babu; Somasekar Seshagiri
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Prophylactic and therapeutic inhibition of allergic airway inflammation by probiotic Escherichia coli O83
Journal of Allergy and Clinical Immunology, ISSN: 10976825 00916749
Christian Zwicker; Priya Sarate; Mirjana Drinić; Katharina Ambroz; Elke Korb; Ursula Smole; Cordula Köhler; Mark S. Wilson; Hana Kozakova; Peter Sebo; Miloslav Kverka; Ursula Wiedermann; Irma Schabussova
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Higher ambient synaptic glutamate at inhibitory versus excitatory neurons differentially impacts NMDA receptor activity
Nature Communications, ISSN: 20411723
Lulu Yao; Teddy Grand; Jesse E. Hanson; Pierre Paoletti; Qiang Zhou
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Erratum to: Clinical activity and molecular correlates of response to atezolizumab alone or in combination with bevacizumab versus sunitinib in renal cell carcinoma (Nature Medicine, (2018), 24, 6, (749-757), 10.1038/s41591-018-0053-3)
Nature Medicine, ISSN: 1546170X 10788956
David McDermott; Mahrukh Huseni; Michael B. Atkins; Robert J. Motzer; Brian I. Rini; Bernard Escudier; Lawrence Fong; Richard W. Joseph; Sumanta Kumar Pal; James A. Reeves; Mario Sznol; John Hainsworth; W. Kimryn Rathmell; Walter M. Stadler; Thomas E. Hutson; Martin E. Gore; Alain Ravaud; Sergio Bracarda; Cristina Suárez; Riccardo Danielli; Viktor Gruenwald; Toni K. Choueiri; Dorothee Nickles; Suchit Jhunjhunwala; Elisabeth Piault-Louis; Alpa Thobhani; Jiaheng Qiu; Daniel S. Chen; Priti Hegde; Christina Schiff; Gregg D. Fine; Thomas Powles
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Application of a Novel ‘Make and Test in Parallel’ Strategy to Investigate the Effect of Formulation on the Pharmacokinetics of GDC-0810 in Healthy Subjects
Pharmaceutical Research, ISSN: 1573904X 07248741
Sravanthi Cheeti; Hao Helen Hou; Eric Nelson; Helen Walker; Buyun Chen; Roland Morley; Mary Gates; Luna Musib; Sandhya Girish; Srikumar Sahasranaman; Lichuan Liu
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Atezolizumab Treatment Beyond Progression in Advanced NSCLC: Results From the Randomized, Phase III OAK Study
Journal of Thoracic Oncology, ISSN: 15561380 15560864
David R. Gandara; Joachim Von Pawel; Julien Mazieres; Richard Sullivan; Åslaug Helland; Ji-Youn Han; Santiago Ponce Aix; Achim Rittmeyer; Fabrice Barlesi; Toshio Kubo; Keunchil Park; Jerome H Goldschmidt; Mayank Gandhi; Cindy Yun; Wei Yu; Christina Matheny; Pei He; Alan Sandler; Ballinger; Louis Fehrenbacher
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Clinical utility of a blood-based EGFR mutation test in patients receiving first-line erlotinib therapy in the ENSURE, FASTACT-2, and ASPIRATION studies
Lung Cancer, ISSN: 18728332 01695002
Yi-Long Wu; Victor Lee; Chong-Kin Liam; Shun Lu; Keunchil Park; Vichien Srimuninnimit; Jie Wang; Caicun Zhou; Anita Appius; Peter Button; Gregory Hooper; John F. Palma; Katja Schulze; Sidney Scudder; David S. Shames; Anny-Yue Yin; Guili Zhang; Tony Mok
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Computer-Based Intensity Measurement Assists Pathologists in Scoring Phosphatase and Tensin Homolog Immunohistochemistry — Clinical Associations in NSCLC Patients of the European Thoracic Oncology Platform Lungscape Cohort
Journal of Thoracic Oncology, ISSN: 15561380 15560864
Undine Rulle; Zoi Tsourti; Ruben Casanova; Karl-Friedrich Deml; Eric K. Verbeken; Erik Thunnissen; Arne Warth; Richard Cheney; Aleksandra Sejda; Ernst Jan M. Speel; Line Bille Madsen; Daisuke Nonaka; Atilio Navarro; Irene Sansano; Antonio Marchetti; Stephen P. Finn; Kim Monkhorst; Keith M. Kerr; Martina Haberecker; Chengguang Wu; Panagiota Zygoura; Roswitha Kammler; Thomas R. Geiger; Steven Gendreau; Katja Schulze; Bart Vrugt; Peter Wild; Holger Moch; Weder; Ata Tuna Ciftlik; Urania Dafni; Solange Peters; Lukas Bubendorf; Rolf A Stahel; Alex Soltermann
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Correction to: Application of a Novel ‘Make and Test in Parallel’ Strategy to Investigate the Effect of Formulation on the Pharmacokinetics of GDC-0810 in Healthy Subjects (Pharmaceutical Research, (2018), 35, 12, (233), 10.1007/s11095-018-2516-0)
Pharmaceutical Research, ISSN: 1573904X 07248741
Sravanthi Cheeti; Hao Helen Hou; Eric Nelson; Helen Walker; Buyun Chen; Roland Morley; Mary Gates; Luna Musib; Sandhya Girish; Srikumar Sahasranaman; Lichuan Liu
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Development and Validation of a High-Quality Composite Real-World Mortality Endpoint
Health Services Research, ISSN: 14756773 00179124
Melissa D. Curtis; Sandra D. Griffith; Melisa Tucker; Michael D. Taylor; William B. Capra; Gillis Carrigan; Ben Holzman; Aracelis Z. Torres; Paul You; Brandon Arnieri; Amy P. Abernethy
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Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events: Methods for item selection in industry-sponsored oncology clinical trials
Clinical Trials, ISSN: 17407753 17407745
Peter C. Trask; Amylou Dueck; Elisabeth Piault; Alicyn Campbell
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Harnessing the Potential of Emerging Digital Health and Biological Sampling Technologies for Clinical Drug Development: Promise to Reality
Clinical Pharmacology and Therapeutics, ISSN: 15326535 00099236
Prajakti A. Kothare; Pravin R. Jadhav; Pankaj Gupta; Jane Croft Harrelson; Leslie Dickmann
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Calpain-mediated tau fragmentation is altered in Alzheimer’s disease progression
Scientific Reports, ISSN: 20452322
Hsu-Hsin Chen; Peter S. Liu; Paul Auger; Seung-Hye Lee; Oskar Adolfsson; Lorianne Rey-Bellet; Julien Lafrance-Vanasse; Brad A. Friedman; Maria Pihlgren; Andreas Muhs; Andrea Pfeifer; James A. Ernst; Gai Ayalon; Kristin R. Wildsmith; Thomas G. Beach; Marcel P Van Der Brug
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TBK1 and IKKε restrain cell death
Nature Cell Biology, ISSN: 14764679 14657392
Klaus D. Heger; Vishva M. Dixit
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Nonclinical safety assessment of a human interleukin-22FC IG fusion protein demonstrates in vitro to in vivo and cross-species translatability
Pharmacology Research and Perspectives, ISSN: 20521707
Donna W. Lee; Shelly Zhong; Rama Pai; Julie Rae; Siddharth Sukumaran; Stefanich; Jeff Lutman; Estelle Doudement; Xiaoting Wang; Brandon Harder; Annemarie N. Lekkerkerker; Ann E. Herman; Wenjun Ouyang; Dimitry Danilenko
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