Unlocking A Cancer Paradox
Genentech scientists discovered a cancer paradox. How can blocking the same pathway have the opposite effect in two different types of cells?
June 2nd, 2013 - Drs. Shiva Malek and Georgia Hatzivassiliou came across a boggling observation. Blocking the BRAF pathway in cancer cells stopped them from growing, like it should. But when the same pathway was blocked in normal cells the opposite happened and cells started growing. Take a deeper look at this discovery that may have important implications for cancer drug discovery and personalized medicine.