Adeyemi Adedeji
Distinguished Scientist-Pathologist, Head of Clinical Pathology, Translational Safety Pathology, Development Sciences
8
Years at Genentech
26
Publications at Genentech
15
Awards & Honors
I obtained my Doctor of Veterinary Medicine (DVM) degree from University of Ibadan in Nigeria, following which I relocated to the United States to pursue my PhD in Molecular Microbiology at the University of Missouri-Columbia. Following the completion of my PhD, I was accepted for a residency training program in veterinary clinical pathology at the University of California-Davis. After the completion of my residency training program, I became a Diplomate of American College of Veterinary Pathologists after passing the board certification exam. Subsequently, I joined the College of Veterinary Medicine, Midwestern University, Glendale, Arizona, as an Assistant Professor of Clinical pathology (tenure-track), where I developed my research lab, mentored professional students interested in biomedical research and also taught clinical pathology courses. I joined Genentech in 2016 as a clinical pathologist to provide scientific support for oncology and non-oncology therapeutic safety and development, along with translational biomarker development.
Featured Publication
Investigating the value of urine volume, creatinine and cystatin c for urinary biomarkers normalization for drug development studies.
Int J Toxicol., 38 (1):12-22. (2019 American College of Toxicology Best Paper Award which was awarded in 2020; Also selected for issue cover).
Adedeji AO*, Pourmohamad T, Chen Y, Burkey J, Betts CJ, Bickerton SJ, Sonee M, McDuffie JE (2019).
My Focus
- Providing clinical pathology expertise to research and preclinical safety studies through well-written reports that accurately reflect data derived from standard clinical pathology endpoints as well as investigative biomarkers and immunotoxicological assessments.
- Serve as investigative toxicologic pathologist on programs with unexpected toxicologic findings
- Serve as Project Pathologist on assigned compounds, targets, and therapeutic areas.
- Effectively assess for pharmacological and toxicological effects of small molecules and biologics in preclinical studies, with a focus on clinical pathology, soluble biomarkers, and immunotoxicology.
- Collaborate with global team of pathologists and other scientists in design of preclinical safety studies and interpretation and communication of study findings, including the impact of the data on the safety profile and clinical development
- In conjunction with the study teams, I contribute an integrated assessment of the significance of study findings to human safety within regulatory submission packages (IND and NDA).
- Provide oversight of review of protocols, data, and reports generated at contract laboratories and maintain effective relationships with CRO clinical pathologists, scientists, and technical staff to ensure high quality, on-time reporting.
- Actively participates in the global drug development process through contributions as Project Pathologist on assigned drug targets
- Work collaboratively within our pathology and investigative safety teams to build our scientific and technical expertise in translational biomarkers and technologies used to support safety studies and in-vivo safety models.
- Drive scientific and technical support for identification, development, qualification, and validation of translational biomarkers and immunological-based endpoints through collaboration with global biomarker and immunotoxicology teams and internal and external expert working groups.
Genentech Publications
Toxicological Sciences, ISSN: 10966080
Leslie J. Valencia; Min Tseng; Mei-Lan Chu; Lanlan Yu; Adedeji; Tomomi Kiyota
Toxicology and Applied Pharmacology, ISSN: 0041008X
Kai Connie Wu; Adedeji; Tanja S. Zabka; Iraj Hosseini; Radhika Kenkre; Jennifer A. Getz; Tien Nguyen; Jérémie Decalf; Travis W. Bainbridge; Jennifer A. Chilton; Christine Moussion; Gautham K. Rao
EXCLI Journal,
Wael Naboulsi; Hannes Planatscher; Felix F. Schmidt; Andreas Steinhilber; Thomas Joos; Adedeji; James E. McDuffie; Oliver Poetz
Altex, ISSN: 1868596X
Roxanne Andaya; Ruth Sullivan; Tony Pourmohamad; Matthew Hayes; Pierre Maliver; Steven T. Laing; Catrin Hasselgren; Noel Dybdal; Adedeji; Lennart T. Anger
Toxicologic Pathology, ISSN: 01926233
Adedeji; Fiona Zhong; Janice Corpuz; Fangyao Hu; Xiaofeng Zhao; Dewakar Sangaraju; Catherine F. Ruff; Noel Dybdal
Animals,
Jessica Graham; Lisa Wong; Adeyemi O. Adedeji; Aija Kusi; Becky Lee; Donna Lee; Noel Dybdal
International Journal of Toxicology, ISSN: 1092874X 10915818
Adedeji; Manisha Sonee; Yafei Chen; Karen Lynch; Katrina Peron; Nicholas King; James E. McDuffie; Petra Vinken
Journal of Pathology Informatics, ISSN: 22295089
Smadar Shiffman; Edgar A. Rios Piedra; Adedeji; Catherine F. Ruff; Rachel N. Andrews; Paula Katavolos; Evan Liu; Ashley Forster; Jochen Brumm; Reina N. Fuji; Ruth Sullivan
Toxicologic Pathology, ISSN: 01926233
Adedeji; Tony Pourmohamad; Niraj K. Tripathi; Shelly Zhong; Kenna R. Degner; Fiona Zhong; Dewakar Sangaraju; Kevin Williams; Noel Dybdal
Toxicologic Pathology, ISSN: 15331601 01926233
Adedeji; Fiona Zhong; Jennifer A. Getz; Zoe Zhong; Wendy Halpern
AAPS Journal, ISSN: 15507416
Hao Cai; Satoko Kakiuchi-Kiyota; Robert Hendricks; Shelly Zhong; Luna Liu; Adedeji; Pamela Chan; Melissa Schutten; Amrita Kamath; Meric A. Ovacik
AAPS Journal,
Hao Cai; Satoko Kakiuchi-Kiyota; Robert Hendricks; Shelly Zhong; Luna Liu; Adedeji; Pamela Chan; Melissa Schutten; Amrita Kamath; Meric A. Ovacik
Veterinary Clinical Pathology, ISSN: 1939165X 02756382
William Siska; A. Eric Schultze; Daniela Ennulat; Kathleen Biddle; Michael Logan; Adedeji; Tara Arndt; Adam Aulbach
Toxicologic Pathology, ISSN: 15331601 01926233
William Siska; A. Eric Schultze; Daniela Ennulat; Kathleen Biddle; Michael Logan; Adedeji; Tara Arndt; Adam Aulbach
Leukemia, ISSN: 14765551 08876924
Satoko Kakiuchi-Kiyota; Thorsten Ross; Heidi J. A. Wallweber; James R. Kiefer; Melissa Schutten; Adedeji; Hao Cai; Robert Hendricks; Sivan Cohen; Srividya Myneni; Luna Liu; Aaron Fullerton; Nick Corr; Lanlan Yu; Denise De Almeida Nagata; Shelly Zhong; Leong; Ji Li; Rin Nakamura; Teiko Sumiyoshi; Jinze Li; Ayse Meric Ovacik; Bing Zheng; Michael Dillon; Christoph Spiess; Susanne Wingert; Erich Rajkovic; Kristina Ellwanger; Uwe Reusch; Andrew G. Polson
Veterinary Clinical Pathology, ISSN: 1939165X 02756382
William Siska; A. Eric Schultze; Daniela Ennulat; Kathleen Biddle; Michael Logan; Adedeji; Tara Arndt; Adam Aulbach
Veterinary Clinical Pathology, ISSN: 02756382
William Siska; A. Eric Schultze; Daniela Ennulat; Kathleen Biddle; Michael Logan; Adedeji; Tara Arndt; Adam Aulbach
Toxicologic Pathology, ISSN: 15331601 01926233
William Siska; A. Eric Schultze; Daniela Ennulat; Kathleen Biddle; Michael Logan; Adedeji; Tara Arndt; Adam Aulbach
Toxicologic Pathology, ISSN: 01926233
William Siska; A. Eric Schultze; Daniela Ennulat; Kathleen Biddle; Michael Logan; Adedeji; Tara Arndt; Adam Aulbach
Leukemia, ISSN: 14765551 08876924
Satoko Kakiuchi-Kiyota; Thorsten Ross; Heidi J. A. Wallweber; James R. Kiefer; Melissa Schutten; Adedeji; Hao Cai; Robert Hendricks; Sivan Cohen; Srividya Myneni; Luna Liu; Aaron Fullerton; Nick Corr; Lanlan Yu; Denise De Almeida Nagata; Shelly Zhong; Steven R. Leong; Ji Li; Rin Nakamura; Teiko Sumiyoshi; Jinze Li; Ayse Meric Ovacik; Bing Zheng; Michael Dillon; Christoph Spiess; Susanne Wingert; Erich Rajkovic; Kristina Ellwanger; Uwe Reusch; Andrew G. Polson
Veterinary Pathology, ISSN: 15442217 03009858
Sara F. Santagostino; Charles-Antoine Assenmacher; James C. Tarrant; Adedeji; Enrico Radaelli
International Journal of Toxicology, ISSN: 1092874X 10915818
Adedeji; Yi-Zhong Gu; Tony Pourmohamad; Justin Kanerva; Yafei Chen; Elnaz Atabakhsh; Michael R. Tackett; Feifei Chen; Bhavana Bhatt; Thierry Gury; Olivier Dorchies; Manisha Sonee; Michelle Morgan; Jennifer Burkey; Jean-Charles Gautier; James E. McDuffie
Journal of Leukocyte Biology, ISSN: 19383673 07415400
Webster; Youngsu C. Kwon; Summer Park; Hua Zhang; Nick Corr; Nina Ljumanovic; Adedeji; Eugene Varfolomeev; Tatiana Goncharov; Jessica Preston; Sara F. Santagostino; Snahel Patel; Min Xu; Jonathan M. Maher; Brent Mckenzie; Domagoj Vucic
Toxicological Sciences, ISSN: 10960929 10966080
Mayur S. Mitra; Karla Lancaster; Adedeji; Gopinath S. Palanisamy; Rutwij A. Dave; Fiona Zhong; Matthew S. Holdren; Shannon J. Turley; Wei-Ching Liang; Yan Wu; Y. Gloria Meng; Jean-Michel Vernes; Melissa Schutten
Veterinary Clinical Pathology, ISSN: 1939165X 02756382
Adedeji; Vimala Vemireddi; Niraj K. Tripathi; Durinck; Jonathan M. Maher; Domagoj Vucic; Wendy Halpern
International Journal of Toxicology, ISSN: 1092874X 10915818
Adedeji; Tony Pourmohamad; Yafei Chen; Jennifer Burkey; Catherine J. Betts; Susan J. Bickerton; Manisha Sonee; James E. McDuffie
Education
- University of California-Davis, Veterinary Clinical Pathology Residency – 2015
- American College of Veterinary Pathologists, Clinical Pathology Diplomate – 2015
- University of Missouri-Columbia, PhD in Molecular Microbiology – 2012
- University of Ibadan, Nigeria, Doctor of Veterinary Medicine – 2005
Awards & Honors
- 3Rs Genentech 1st place Award, Refinement category: Applying the 3Rs to urinalysis assessments in toxicity studies: refining procedures and adopting a case-by-case approach – 2024
- Society of Toxicology, Biotechnology Specialty Section (SOT-BTSS) Award for the Best Paper published in Toxicological Sciences: Zoledronic acid and ibandronate-ind – 2023
- 3Rs Global Roche 1st place award, Lab animal care category: Reduced Fasting Duration in Cynomolgus Monkeys Enhances Animal Welfare During Toxicology Studies – 2023
- Development Sciences end of the year award: “The power of we” (Safety Biomarker Expert Resources) – 2022
- American College of Toxicology (ACT) Best Paper Award: “Investigating the Value of Urine Volume, Creatinine, and Cystatin C for Urinary Biomarkers Normalization for Drug Development Studies – 2020
- Genentech Development Sciences Recognition Award for a high performing employee – 2020
- Genentech RIP1 program Creative Genius Award for innovative investigation and creative hypotheses generation – 2018
- Genentech RIP1 program Creative Genius Award for innovative investigation and creative hypotheses generation – 2017
- University of Missouri Recognition Award for Innovation: Suppression of SARS replication by SARS helicase inhibitors – 2016
- Linda Munson Memorial Award Recipient – 2015
- CL Davis Award – 2015
- Resident Externship Training in Industry scholarship – 2014
- Dr. Liman Ciroma Prize for the Best Student with the Highest GPA during the DVM Degree Program – 2005
- The Nupemeco Prize for All-round Best Student. i.e. highest departmental prizes in the Faculty – 2005
- Mr. Olagoke Oladinni Prize for the Best Final Year DVM Student In Veterinary Medicinex – 2005