Anwesha Dey
Principal Scientist and Director, Discovery Oncology
Postdoc Mentor
"Genentech offers the incredible opportunity to pursue curiosity-driven intellectual inquiry and touch the lives of patients."
13
Years at Genentech
27
Publications at Genentech
4
Awards & Honors
The focus of my lab is to gain new insights into signaling pathways in cancer biology. We are interested in identifying and validating new targets to contribute to the oncology drug discovery efforts. Working at Genentech offers the unique opportunity to focus on both cutting edge basic biology and translating our basic science discoveries for therapeutic intervention to potentially help patients.
Postdoctoral Mentor
I know first hand how enriching and rewarding the postdoc program at Genentech is. Joining Genentech as a postdoctoral fellow in Vishva Dixit’s lab was one of the best career decisions I ever took. The postdoc program at Genentech offers the opportunity to immerse oneself in the best science possible and collaborate with excellent scientists across multiple disciplines. Postdoc projects advance basic science, which often lays the foundation for key therapeutic discoveries. I feel very fortunate to have the opportunity to be a postdoc mentor.
Featured Publication
NeuCode Proteomics Reveals Bap1 Regulation of Metabolism.
Cell Rep. 2016 Jun 30. pii: S2211-1247(16)30738-0. doi: 10.1016/j.celrep.2016.05.096. [Epub ahead of print]
Baughman JM, Rose CM, Kolumam G, Webster JD, Wilkerson EM, Merrill AE, Rhoads TW, Noubade R, Katavolos P, Lesch J, Stapleton DS, Rabaglia ME, Schueler KL, Asuncion R, Domeyer M, Zavala-Solorio J, Reich M, DeVoss J, Keller MP, Attie AD, Hebert AS, Westphall MS, Coon JJ, Kirkpatrick DS, Dey A.
Loss of the tumor suppressor BAP1 causes myeloid transformation.
Science 2012, Aug. 9.
Dey A, Seshasayee D, Noubade R, French DM, Liu J, Chaurushiya MS, Kirkpatrick DS, Pham VC, Lill JR, Bakalarski CE, Wu J, Phu L, Katavolos P, Saunders LM, Abdel-Wahab O, Modrusan Z, Seshagiri S, Dong K, Lin Z, Balazs M, Suriben R, Newton K, Hymowitz S, Garcia-Manero G, Martin F, Levine RL, Dixit VM.
My Focus
My lab currently has two focus areas: (a) Understanding the basic biology of the hippo signaling pathway and how it is deregulated in various cancers; and (b) investigating the tumor suppressor BAP1 and uncovering its roles in cancer, metabolism and development. Broadly, my lab uses a variety of biochemical and proteomics tools, cellular and mouse models to investigate how signaling pathways are deregulated in cancers.
Genentech Publications
Cancer Discovery, ISSN: 21598290 21598274
Kyung W. Song; Kyle A. Edgar; Emily J. Hanan; Marc Hafner; Jason Oeh; Mark Merchant; Deepak Sampath; Michelle Nannini; Rebecca Hong; Lilian Phu; William F. Forrest; Eric Stawiski; Stephen Schmidt; Nicholas F. Endres; Jane Guan; Jeffery J. Wallin; Jonathan Cheong; Emile G. Plise; Gail D. Lewis Phillips; Laurent Salphati; Timothy P. Heffron; Alan G. Olivero; Shiva Malek; Steven T. Staben; Donald S. Kirkpatrick; Anwesha Dey; Lori S. Friedman
Cancer Discovery, ISSN: 21598290 21598274
Trang Pham; Thijs Hagenbeek; Ho-June Lee; Jason Li; Christopher M. Rose; Eva Lin; Mamie Yu; Scott E. Martin; Robert Piskol; Jennifer A. Lacap; Deepak Sampath; Victoria Pham; Zora Modrusan; Jennie R. Lill; Christiaan N. Klijn; Shiva Malek; Matthew T. Chang; Anwesha Dey
Journal of the American Society of Nephrology, ISSN: 15333450 10466673
Jun-Jae Chung; Leonard D. Goldstein; Ying-Jiun J. Chen; Jiyeon Lee; Webster; Merone Roose-Girma; Sharad C. Paudyal; Zora Modrusan; Anwesha Dey; Andrey S. Shaw
Trends in Cancer, ISSN: 24058033
Aishwarya Kulkarni; Matthew T. Chang; Joseph H.A. Vissers; Anwesha Dey; Kieran F. Harvey
Nature Reviews Drug Discovery, ISSN: 14741784 14741776
Anwesha Dey; Xaralabos Varelas; Kun-Liang Guan
Journal of Clinical Investigation, ISSN: 15588238 00219738
Wei Zou; Nidhi Rohatgi; Jonathan R. Brestoff; John R. Moley; Yongjia Li; Jesse W. Williams; Yael Alippe; Hua Pan; Terri A. Pietka; Gabriel Mbalaviele; Elizabeth P. Newberry; Nicholas O. Davidson; Anwesha Dey; Kooresh I. Shoghi; Richard D. Head; Samuel A. Wickline; Gwendalyn J. Randolph; Nada A. Abumrad; Steven L. Teitelbaum
Cancer Research, ISSN: 15387445 00085472
Ho-June Lee; Trang Pham; Matthew T. Chang; Dwight Barnes; Allen G. Cai; Rajkumar Noubade; Klara Totpal; Xu Chen; Christopher Tran; Thijs Hagenbeek; Xiumin Wu; Jeffrey Eastham-Anderson; Janet Tao; Wyne P. Lee; Boris C. Bastian; Carbone; Webster; Anwesha Dey
Frontiers in Cell and Developmental Biology, ISSN: 2296634X
Satoko Kakiuchi-Kiyota; Melissa Schutten; Yu Zhong; James J. Crawford; Anwesha Dey
JCI insight, ISSN: 23793708
Tianhe Sun; Zhiyu Huang; Hua Zhang; Clara Posner; Guiquan Jia; Thirumalai R. Ramalingam; Min Xu; Hans D. Brightbill; Jackson G. Egen; Anwesha Dey; Joseph R. Arron
Trends in Cancer, ISSN: 24058033
Philamer C. Calses; James J. Crawford; Jennie R. Lill; Anwesha Dey
The tumor suppressor BAP1 cooperates with BRAFV600E to promote tumor formation in cutaneous melanoma
Pigment Cell and Melanoma Research, ISSN: 1755148X 17551471
Webster; Trang Pham; Xiumin Wu; Nicolas W. Hughes; Zhongwu Li; Klara Totpal; Ho-June Lee; Philamer C. Calses; Mira S. Chaurushiya; Eric Stawiski; Zora Modrusan; Matthew T. Chang; Christopher Tran; Wyne P. Lee; Sreedevi Chalasani; Jeffrey Hung; Neeraj Sharma; Sara M. Chan; Kathy Hötzel; Eric Talevich; Alan Shain; Mengshu Xu; Jennie R. Lill; Vishva M. Dixit; Boris C. Bastian; Anwesha Dey
Science, ISSN: 10959203 00368075
Meng He; Mira S. Chaurushiya; Webster; Sarah K. Kummerfeld; Rohit Reja; Subhra Chaudhuri; Ying-Jiun Chen; Zora Modrusan; Benjamin Haley; Dugger; Jeffrey Eastham-Anderson; Shari Lau; Anwesha Dey; Roger Caothien; Merone Roose-Girma; Kim Newton; Vishva M. Dixit
npj Precision Oncology, ISSN: 2397768X
Kwame Okrah; Somayeh S. Tarighat; Bonnie Liu; Koeppen; Marie-Claire Wagle; Cheng; Sun; Anwesha Dey; Chang; Teiko Sumiyoshi; Zineb Mounir; Cummings; Garret M. Hampton; Lukas Amler; Jane Fridlyand; Priti Hegde; Shannon J. Turley; Lackner; Shih-Min A. Huang
npj Precision Oncology, ISSN: 2397768X
Kwame Okrah; Somayeh S. Tarighat; Bonnie Liu; Koeppen; Marie-Claire Wagle; Cheng; Sun; Anwesha Dey; Chang; Sumiyoshi; Zineb Mounir; Cummings; Garret M. Hampton; Lukas Amler; Jane Fridlyand; Priti Hegde; Shannon J. Turley; Lackner; Shih-Min A. Huang
Science Signaling, ISSN: 19379145 19450877
Thijs Hagenbeek; Webster; Noelyn Kljavin; Matthew T. Chang; Trang Pham; Ho-June Lee; Christiaan N. Klijn; Allen G. Cai; Klara Totpal; Buvana Ravishankar; Nai-Ying Yang; Da-Hye Lee; Kevin B. Walsh; Georgia Hatzivassiliou; Cecile C. de la Cruz; Stephen Gould; Xiumin Wu; Wyne P. Lee; Shuqun Yang; Zhixiang Zhang; Qingyang Gu; Qunsheng Ji; Erica L. Jackson; Dae-Sik Lim; Anwesha Dey
Science immunology, ISSN: 24709468
Teresita L. Arenzana; Steve Lianoglou; Akiko Seki; Celine Eidenschenk; Tommy K. Cheung; Dhaya Seshasayee; Thijs Hagenbeek; Arivazhagan Sambandam; Rajkumar Noubade; Ivan Peng; Justin Lesch; Jason Devoss; Xiumin Wu; Wyne P. Lee; Patrick Caplazi; Webster; Jinfeng Liu; Victoria Pham; David Arnott; Jennie R. Lill; Zora Modrusan; Anwesha Dey; Sascha Rutz
Cancer Discovery, ISSN: 21598290 21598274
Yi-Feng Gu; Shannon Cohn; Alana Christie; Tiffani McKenzie; Nicholas Wolff; Quyen N. Do; Ananth J. Madhuranthakam; Ivan Pedrosa; Tao Wang; Anwesha Dey; Meinrad Busslinger; Xian-Jin Xie; Robert E. Hammer; Renée M. McKay; Payal Kapur; James Brugarolas
Cell Reports, ISSN: 22111247
Joshua M. Baughman; Christopher M. Rose; Ganesh Kolumam; Webster; Emily M. Wilkerson; Anna E Merrill; Timothy W. Rhoads; Rajkumar Noubade; Paula Katavolos; Justin Lesch; Donald S. Stapleton; Mary E. Rabaglia; Kathy L. Schueler; Raymond Asuncion; Melanie Domeyer; Jose Zavala-Solorio; Michael Reich; Jason Devoss; Mark P. Keller; Alan D. Attie; Alexander S. Hebert; Michael S. Westphall; Joshua J Coon; Donald S. Kirkpatrick; Anwesha Dey
Oncogene, ISSN: 14765594 09509232
Napolitano; Pellegrini; Anwesha Dey; Larson; Tanji; Flores; Kendrick; Lapid; Powers; Kanodia; Pastorino; Pass; Vishva M. Dixit; Yang; Carbone
Structure, ISSN: 18784186 09692126
Cameron Noland; Sarah Gierke; Paul D. Schnier; Jeremy Murray; Wendy N. Sandoval; Meredith Sagolla; Anwesha Dey; Rami N. Hannoush; Wayne J. Fairbrother; Christian N. Cunningham
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 10916490 00278424
Shan-Shan Wang; Yi-Feng Gu; Nicholas Wolff; Karoliina Stefanius; Alana Christie; Anwesha Dey; Robert E. Hammer; Xian-Jin Xie; Dinesh Rakheja; Ivan Pedrosa; Thomas Carroll; Renée M. McKay; Payal Kapur; James Brugarolas
Methods in Molecular Biology, ISSN: 10643745
Anwesha Dey; Jiansheng Wu; Donald S. Kirkpatrick
Methods in Molecular Biology, ISSN: 10643745
Anwesha Dey; Jiansheng Wu; Donald S. Kirkpatrick
Journal of Experimental Medicine, ISSN: 00221007 15409538
Omar Abdel-Wahab; Jie Gao; Mazhar Adli; Anwesha Dey; Thomas Trimarchi; Young Rock Chung; Cem Kuscu; Todd Hricik; Delphine Ndiaye-Lobry; Lindsay M. LaFave; Richard Koche; Alan H. Shih; Olga A. Guryanova; Eunhee Kim; Sheng Li; Suveg Pandey; Joseph Y. Shin; Leon Telis; Jinfeng Liu; Parva K. Bhatt; Sebastien Monette; Xinyang Zhao; Christopher E Mason; Christopher Y. Park; Bradley E. Bernstein; Iannis Aifantis; Ross L. Levine
Leukemia, ISSN: 08876924 14765551
Omar Abdel-Wahab; Anwesha Dey
Science, ISSN: 10959203 00368075
Anwesha Dey; Dhaya Seshasayee; Rajkumar Noubade; French; Jinfeng Liu; Mira S. Chaurushiya; Donald S. Kirkpatrick; Victoria Pham; Jennie R. Lill; Corey Bakalarski; Jiansheng Wu; Lilian Phu; Paula Katavolos; Lindsay M. LaFave; Omar Abdel-Wahab; Zora Modrusan; Somasekar Seshagiri; Ken Dong; Zhonghua Lin; Mercedesz Balazs; Rowena Suriben; Kim Newton; Sarah G. Hymowitz; Guillermo Garcia-Manero; Flavius Martin; Ross L. Levine; Vishva M. Dixit
Nature Cell Biology, ISSN: 14657392
Yaron Pereg; Bob Y. Liu; Karen M. O'Rourke; Meredith Sagolla; Anwesha Dey; László Kömüves; French; Vishva M. Dixit
Education
- Genentech 2009-2012, Postdoctoral Fellow – 2009-2012
- Institute of Molecular and Cell Biology, ASTAR Singapore, Postdoctoral Fellow – 2005-2009
- University of Maryland at Baltimore County, HHMI , Ph.D – 2001-2004
- National University of Singapore, B.Sc. – 1998-2000
Awards & Honors
- 1st Place, Graduate Research Conference, University of Maryland – 2003 & 2004
- National Science Scholarship, Agency for Science Technology and Research (ASTAR), Singapore – 2001-2004
- Dean’s list, Faculty of Science, National University of Singapore – 2000
- 1st. Place in Undergraduate Chemistry and Biological Sciences Symposium, University of Maryland – 2000