Jawahar Sudhamsu

My area of expertise is protein biochemistry and structural biology. My group utilizes various structural methods (X-ray crystallography, Cryo-EM) and protein biochemistry to study interactions of macromolecules and contribute to better understanding of signaling events in human disease and to drug discovery. In addition, we identify bottlenecks and develop technology to accelerate research processes in an effort to enable and speed up basic research and drug discovery.

My research interests focus on molecular mechanisms of signaling in cancer. These signaling cascades are tightly regulated and fine-tuned for promoting growth when needed. Not surprisingly, cancer cells take advantage of these effective cascades by overcoming multiple regulatory mechanisms. By understanding the molecular mechanisms of signaling in a healthy and cancerous cell, my hope is that we will be better able to design more effective therapies.

• Genentech, Department of Structural Biology, Postdoctoral Fellow – 2014
• Cornell University, Chemistry and Chemical Biology, Ph. D. – 2009
• Indian Institute of Technology, Chemistry, Integrated M. Sc – 2003