Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 1 - 50 OF 11054 RESULTS

Optimization of a two-dimensional liquid chromatography-supercritical fluid chromatography-mass spectrometry (2D-LC-SFS-MS) system to assess “in-vivo” inter-conversion of chiral drug molecules
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, ISSN: 15700232
Meenakshi Goel; Eli Larson; C.J. Venkatramani; Mohammad Al-Sayah
Pharmaceutical Research, ISSN: 1573904X 07248741
Rosa Chan; Tom De Bruyn; Matthew Wright; Broccatelli
Inhibition of Endothelial NOTCH1 Signaling Attenuates Inflammation by Reducing Cytokine-Mediated Histone Acetylation at Inflammatory Enhancers
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN: 10795642
Lars La Cour Poulsen; Reidunn Jetne Edelmann; Stig Krüger; Rodrigo Diéguez-Hurtado; Akshay Shah; Tor Espen Stav-Noraas; Anastasia Renzi; Monika Szymanska; Junbai Wang; Manuel Ehling; Rui Benedito; Monika Kasprzycka; Espen Bækkevold; Olav Sundnes; Kim S. Midwood; Helge Scott; Philippe Collas; Chris Siebel; Ralf H. Adams; Guttorm Haraldsen; Eirik Sundlisæter; Johanna Hol
Journal of the American Academy of Dermatology, ISSN: 10976787 01909622
Thomas B. Casale; Patrick H. Win; Jonathan A. Bernstein; Karin Rosen; Michael Holden; Ahmar Iqbal; Ben Trzaskoma; Ming Yang; Jenya Antonova; Thomas Murphy; Mark D. Scarupa; Howard Sofen; Allen P. Kaplan
Stem Cell Research, ISSN: 18767753 18735061
Ioana Neagoe; Chang Liu; Alexander Stumpf; Yanmei Lu; Dongping He; Ross Francis; Jun Chen; Paul Reynen; Moulay Hicham Alaoui-Ismaili; Hirokazu Fukui
Discovery of GDC-0853: A Potent, Selective, and Noncovalent Bruton's Tyrosine Kinase Inhibitor in Early Clinical Development
Journal of Medicinal Chemistry, ISSN: 00222623
James J. Crawford; Adam Johnson; Misner; Lisa Belmont; Georgette Castanedo; Regina Choy; Melis Coraggio; Liming Dong; Charles Eigenbrot; Rebecca Erickson; Nico Ghilardi; Jonathan Hau; Arna Katewa; Pawan Bir Kohli; Wendy Lee; Joe Lubach; Brent McKenzie; Dan Ortwine; Leah Schutt; Suzanne Brown; Binqing Wei; Karin Reif; Lichuan Liu; Harvey Wong; Wendy Young
Health-related quality of life impact of cobimetinib in combination with vemurafenib in patients with advanced or metastatic BRAFV600 mutation-positive melanoma
British Journal of Cancer, ISSN: 00070920
Brigitte Dréno; Paolo A. Ascierto; Victoria Atkinson; Gabriella Liszkay; Michele Maio; Mario Mandala; Lev Demidov; Daniil Stroyakovskiy; Luc Thomas; Luis De La Cruz-Merino; Caroline Dutriaux; Claus Garbe; Karen Bartley; Thomas Karagiannis; Ilsung Chang; Isabelle Rooney; Daniel Koralek; James Larkin; McArthur; Antoni Ribas
Targeting the hippo pathway and cancer through the TEAD family of transcription factors
Cancers,
Jeffrey K. Holden; Christian Cunningham
Previously reported placebo-response-associated variants do not predict patient outcomes in inflammatory disease Phase III trial placebo arms
Genes and Immunity, ISSN: 14664879
Asher Haug-Baltzell; Tushar Bhangale; Diana Chang; Amy Dressen; Brian Yaspan; Ward Ortmann; Matt Brauer; Julie Hunkapiller; Jens Reeder; Kiran Mukhyala; Karen T. Cuenco; Jennifer A. Tom; Amy Cowgill; Jan Vogel; Bill Forrest; Timothy W. Behrens; Rob Graham; Art Wuster
Organic Process Research and Development, ISSN: 1520586X 10836160
Chong Han; Keena Green; Kathrin Oehring; Arthur Meili; Eugen Pfeifer; Michelangelo Scalone; Francis Gosselin
In vitro model for predicting bioavailability of subcutaneously injected monoclonal antibodies
Journal of Controlled Release, ISSN: 01683659
Hanne Kinnunen Bown; Catherine Bonn; Stefan Yohe; Daniela Yadav; Thomas Patapoff; Ann Daugherty; Randall J. Mrsny
Molecular Pharmaceutics, ISSN: 15438392 15438384
Paroma Chakravarty; Keyur Pandya; Karthik Nagapudi
Molecular Pharmaceutics, ISSN: 15438392 15438384
Abbe Haser; Tu Cao; Joe Lubach; Feng Zhang
Cancer Research, ISSN: 15387445 00085472
Benjamin R. Leadem; Ioannis Kagiampakis; Catherine Wilson; Tommy K Cheung; David Arnott; Patrick Trojer; Marie Classon; Hariharan Easwaran; Stephen B. Baylin
Journal of Rheumatology, ISSN: 14992752 0315162X
Jennie Best; Amanda M. Kong; Gregory M. Lenhart; Khaled Sarsour; Marni Stott-Miller; Yong Hwang
Cell Death and Disease, ISSN: 20414889
Marinella Callow; Colin Watanabe; Kate Wickliffe; Russell Bainer; Sarah Kummerfield; Julie Weng; Trinna Cuellar; Vasant Janakiraman; Honglin Chen; Ben Chih; Yuxin Liang; Benjamin Haley; Kim Newton; Mike Costa
Pharmaceutical Research, ISSN: 1573904X 07248741
Ming Lei; Cynthia Quan; John Wang; Yung-Hsiang Kao; Christian Schöneich
Journal of Physical Chemistry B, ISSN: 15205207 15206106
Gennady Khirich; Michael J. Holliday; Jasper Lin; Aditya Nandy
Journal of Experimental Medicine, ISSN: 15409538 00221007
Akiko Seki; Sascha Rutz
Journal of Investigative Medicine, ISSN: 17088267 10815589
Shuqian Liu; Daphne T. Adelman; Yaping Xu; Jillone Sisco; Susan Begelman; Susan M. Webb; Xavier Badia; Tina K. Thethi; Vivian Fonseca; Lizheng Shi
AAPS Journal, ISSN: 15507416
Ian Templeton; Nicholas S. Jones; Luna Musib
Pharmaceutical Research, ISSN: 1573904X 07248741
Joe Lubach; Jonathan Hau
Rheumatology, ISSN: 14620332 14620324
Ernest Choy; Roberto Caporali; Ricardo Xavier; Bruno Fautrel; Raimón Sanmarti; Min Bao; Corrado Bernasconi; Attila Pethö-Schramm
Veterinary Pathology, ISSN: 15442217 03009858
Yu Zhong; Donna Dambach; Jonathan M. Maher
Nature Immunology, ISSN: 15292916 15292908
Etienne Patin; Milena Hasan; Jacob Bergstedt; Vincent Rouilly; Valentina Libri; Alejandra Urrutia; Cécile Alanio; Petar Scepanovic; Christian Hammer; Friederike Jönsson; Benoît Beitz; Hélène Quach; Yoong Wearn Lim; Julie Hunkapiller; Magge Zepeda; Cherie Green; Barbara Piasecka; Claire Leloup; Lars Rogge; François Huetz; Isabelle Peguillet; Olivier Lantz; Magnus Fontes; James P. Santo; Stéphanie Thomas; Jacques Fellay; Darragh Duffy; Lluis Quintana-Murci; Matthew Albert; Laurent Abel; Andres Alcover; Kalla Astrom; Philippe Bousso; Pierre Bruhns; Ana Cumano; Caroline Demangel; Ludovic Deriano; James P. Di Santo; Françoise Dromer; Gérard Eberl; Jost Enninga; Antonio Freitas; Odile Gelpi; Ivo Gomperts Boneca; Serge Hercberg; Claude Leclerc; Hugo Mouquet; Sandra Pellegrini; Stanislas Pol; Anavaj Sakuntabhai; Olivier Schwartz; Benno Schwikowski; Spencer Shorte; Vassili Soumelis; Frédéric Tangy; Eric Tartour; Antoine Toubert; Marie-Noëlle Ungeheuer
The Lancet Oncology, ISSN: 14745488 14702045
Jennifer L. McQuade; Carrie R. Daniel; Kenneth R. Hess; Carmen Mak; Daniel Y. Wang; Rajat R. Rai; John J. Park; Lauren Haydu; Christine Spencer; Matthew Wongchenko; Stephen Lane; Dung-Yang Lee; Mathilde Kaper; Meredith McKean; Kathryn E. Beckermann; Samuel M. Rubinstein; Isabelle Rooney; Luna Musib; Nageshwar Budha; Jessie Hsu; Theodore S. Nowicki; Alexandre Avila; Tomas Haas; Maneka Puligandla; Sandra Lee; Shenying Fang; Jennifer A. Wargo; Jeffrey E. Gershenwald; Jeffrey E Lee; Patrick Hwu; Paul B. Chapman; Jeffrey A Sosman; Dirk Schadendorf; Jean-Jacques Grob; Keith Flaherty; Dana Walker; Yibing Yan; Edward McKenna; Jeffrey J. Legos; Matteo S. Carlino; Antoni Ribas; John M. Kirkwood; Georgina V. Long; Douglas B. Johnson; Alexander M. Menzies; Michael A. Davies
Pharmacological Research, ISSN: 10961186 10436618
Daqi Xu; Marissa L. Matsumoto; Brent McKenzie; Ali Zarrin
Exploring Molecular Speciation and Crystallization Mechanism of Amorphous 2-Phenylamino Nicotinic Acid
Pharmaceutical Research, ISSN: 07248741
Arjun Kalra; Joe Lubach; Eric Munson; Tonglei Li
Chemistry - A European Journal, ISSN: 15213765 09476539
Xin Linghu; Nathaniel Segraves; Ifat Abramovich; Nicholas Wong; Barbara Müller; Nadja Neubauer; Serena M. Fantasia; Sebastian Rieth; Stephan Bachmann; Michael Jansen; C. Gregory Sowell; David Askin; Stefan Koenig; Francis Gosselin
Journal of Physical Chemistry B, ISSN: 15205207 15206106
Wenhua Wang; Wayne Lilyestrom; Zhi Yu Hu; Tom Scherer
Nature, ISSN: 14764687 00280836
Sanjeev Mariathasan; Shannon Turley; Dorothee Nickles; Alessandra Castiglioni; Kobe Yuen; Yulei Wang; Edward E. Kadel III; Hartmut Koeppen; Jillian Astarita; Rafael Cubas; Suchit Jhunjhunwala; Romain Banchereau; Yagai Yang; Yinghui Guan; Cecile Chalouni; James Ziai; Yasin Senbabaoglu; Stephen Santoro; Daniel Sheinson; Jeffrey Hung; Jennifer Giltnane; Andrew A Pierce; Kathryn Mesh; Steve Lianoglou; Johannes Riegler; Rick Carano; Pontus Eriksson; Mattias Höglund; Loan Somarriba; Daniel L Halligan; Michiel S Van Der Heijden; Yohann Loriot; Jonathan E. Rosenberg; Lawrence Fong; Ira Mellman; Daniel Chen; Marjorie Green; Christina L. Derleth; Gregg Fine; Priti Hegde; Richard Bourgon; Thomas Powles
Bioconjugate Chemistry, ISSN: 15204812 10431802
Rachana Ohri; Sunil Bhakta; Aimee Fourie-O'Donohue; Josefa Dela Cruz Chuh; Siao Ping Tsai; Ryan Cook; Binqing Wei; Carl Ng; Athena Wong; Aaron Bos; Farzam Farahi; Jiten Bhakta; Thomas Pillow; Helga Raab; Dick Vandlen; Paul Polakis; Yichin Liu; Hans Erickson; Jagath Reddy Junutula; Kathy Kozak
Bioconjugate Chemistry, ISSN: 15204812 10431802
Donglu Zhang; Hoa Le; Josefa Dela Cruz-Chuh; Sudheer Bobba; Jun Guo; Leanna Staben; Chenghong Zhang; Yong Ma; Kathy Kozak; Gail Phillips; Breanna S. Vollmar; Jack D. Sadowsky; Dick Vandlen; Binqing Wei; Dian Su; Peter Fan; Peter Dragovich; Cyrus Khojasteh; Marcel Hop; Thomas Pillow
Journal of Clinical Oncology, ISSN: 15277755 0732183X
John Hainsworth; Funda Meric-Bernstam; Charles Swanton; Herbert Hurwitz; David Spigel; Christopher J. Sweeney; Howard A. Burris; Ron Bose; Bongin Yoo; Alisha Stein; Beattie; Razelle Kurzrock
Neuro-Oncology, ISSN: 15235866 15228517
Tim Heffron
Organic Letters, ISSN: 15237052 15237060
Ngiap-Kie Lim; Theresa Cravillion; Scott Savage; Andrew McClory; Chong Han; Haiming Zhang; Antonio Dipasquale; Francis Gosselin
Organic Letters, ISSN: 15237052 15237060
Cosme Sandoval; Ngiap-Kie Lim; Haiming Zhang
Molecular Cell, ISSN: 10974164 10972765
Tanya Goncharov; Stefanie Hedayati; Melinda M. Mulvihill; Anita Izrael-Tomasevic; Kerry Zobel; Surinder Jeet; Anna Fedorova; Celine Eidenschenk; Jason DeVoss; Kebing Yu; Andrey S. Shaw; Don Kirkpatrick; Wayne Fairbrother; Kurt Deshayes; Domagoj Vucic
Nature Chemical Biology, ISSN: 15524469 15524450
Ruedi Aebersold; Jeffrey N Agar; I Jonathan Amster; Mark S Baker; Carolyn Bertozzi; Emily S Boja; Catherine E Costello; Benjamin F Cravatt; Catherine Fenselau; Benjamin A. Garcia; Ying Ge; Jeremy Gunawardena; Ronald C Hendrickson; Paul J Hergenrother; Christian G Huber; Alexander R Ivanov; Ole N Jensen; Michael C Jewett; Neil L Kelleher; Laura Kiessling; Nevan J. Krogan; Martin R Larsen; Joseph A Loo; Rachel R Ogorzalek Loo; Emma Lundberg; Michael J. MacCoss; Parag Mallick; Vamsi K Mootha; Milan Mrksich; Tom W Muir; Steven M Patrie; James J Pesavento; Sharon J Pitteri; Henry Rodriguez; Alan Saghatelian; Wendy Sandoval; Hartmut Schlüter; Salvatore Sechi; Sarah A Slavoff; Lloyd M Smith; Michael Snyder; Paul M Thomas; Mathias Uhlén; Jennifer E Van Eyk; Marc Vidal; David R Walt; Forest M. White; Evan R Williams; Therese Wohlschlager; Vicki H Wysocki; Nathan A Yates; Nicolas L Young; Bing Zhang
BMC Medical Genetics, ISSN: 14712350
Viswanathan Mohan; Venkatesan Radha; Thong Tom Nguyen; Eric Stawiski; Kanika Bajaj Pahuja; Leonard Goldstein; Jennifer A. Tom; Ranjit Mohan Anjana; Monica Beltran; Tushar Bhangale; Suresh Jahnavi; Radhakrishnan Chandni; Vijay Gayathri; Paul George; Na Zhang; Sakthivel Murugan; Sameer Phalke; Subhra Chaudhuri; Ravi Gupta; Jingli Zhang; Sam Santhosh; Jeremy Stinson; Zora Modrusan; Vedam Laxmi Ramprasad; Somasekar Seshagiri; Andrew Peterson
Journal of Medicinal Chemistry, ISSN: 15204804 00222623
Binqing Wei; Janet Gunzner-Toste; Hui Yao; Tao Wang; Jing Wang; Zijin Xu; Jinhua Chen; John Wai; Jim Nonomiya; Siao Ping Tsai; Josefa Chuh; Kathy Kozak; Yichin Liu; Shang-Fan Yu; Jeffrey Lau; Ginny Li; Gail D. Phillips; Douglas Leipold; Amrita Kamath; Dian Su; Keyang Xu; Charles Eigenbrot; Stefan Steinbacher; Rachana Ohri; Helga Raab; Leanna Staben; Guiling Zhao; John Flygare; Thomas Pillow; Vishal Verma; Luke Masterson; Philip W. Howard; Brian Safina
eLife, ISSN: 2050084X
Daniel J. Fazakerley; Rima Chaudhuri; Pengyi Yang; Ghassan J. Maghzal; Kristen C. Thomas; James R. Krycer; Sean J. Humphrey; Benjamin L. Parker; Kelsey H. Fisher-Wellman; Christopher C. Meoli; Nolan J. Hoffman; Ciana Diskin; James G. Burchfield; Mark J. Cowley; Warren Kaplan; Zora Modrusan; Ganesh Kolumam; Jean Y. H. Yang; Daniel L. Chen; Samocha-Bonet; Jerry R. Greenfield; Kyle L. Hoehn; Roland Stocker; David E. James
Grking the smoothened signal
Science Signaling, ISSN: 19450877
Hayley Sharpe; Frederic De Sauvage
Oncologist, ISSN: 1549490X 10837159
Leslie Dickmann; Jennifer L. Schutzman
Regulatory Toxicology and Pharmacology, ISSN: 10960295 02732300
Jinze Li; Eric Morinello; Thomas Larsen; Denzil Frost; Ivor Caro; Stephen Gould; Lisa Wong; Angela Hendricks; Noel Dybdal; Donna Dambach; Melissa Schutten
Clinical Pharmacology and Therapeutics, ISSN: 15326535 00099236
Edna Choo; Laurent Salphati
Pharmacokinetics and exposure-response analysis of RG7667, a combination of two anticytomegalovirus monoclonal antibodies, in a phase 2a randomized trial to prevent cytomegalovirus infection in high-risk kidney transplant recipients
Antimicrobial Agents and Chemotherapy, ISSN: 00664804
Rong Deng; Yehong Wang; Mauricio Maia; Tracy Burgess; Jacqueline McBride; X. Charlene Liao; Jorge Tavel; William D. Hanley
Pharmaceutical Research, ISSN: 1573904X 07248741
Lin Zhang; Sandeep Yadav; John Wang; Olivier Mozziconacci; Christian Schӧneich