Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 701 - 750 OF 15166 RESULTS

Drug–Drug Interaction Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Ipatasertib in Combination with Darolutamide in Patients with Advanced Prostate Cancer
Pharmaceutics, ISSN: 19994923
Dhruvitkumar S. Sutaria; Grozdana Rasuo; Adam Harris; Ryan Johnson; Dale Miles; Jorge Daniel Gallo; Rucha Sane
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Event-Free Survival in Patients with Early HER2-Positive Breast Cancer with a Pathological Complete Response after HER2-Targeted Therapy: A Pooled Analysis
Cancers, ISSN: 20726694
Sandra M. Swain; Harrison Macharia; Javier Cortés; Chau T. Dang; Luca Gianni; Sara A. Hurvitz; Christian Jackisch; Andreas Schneeweiss; Dennis J. Slamon; Pinuccia Valagussa; du Toit; Dominik Heinzmann; Adam Knott; Chunyan Song; Patricia Cortazar
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Altered Bioavailability and Pharmacokinetics in Crohn’s Disease: Capturing Systems Parameters for PBPK to Assist with Predicting the Fate of Orally Administered Drugs
Clinical Pharmacokinetics, ISSN: 11791926 03125963
Sarah Alrubia; Jialin Mao; Yuan Chen; Jill Barber; Amin Rostami-Hodjegan
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Airway remodelling rather than cellular infiltration characterizes both type2 cytokine biomarker-high and -low severe asthma
Allergy: European Journal of Allergy and Clinical Immunology, ISSN: 13989995 01054538
Latifa Khalfaoui; Fiona A. Symon; Simon Couillard; Beverley Hargadon; Rekha Chaudhuri; Steve Bicknell; Adel Mansur; Rahul Shrimanker; Timothy S.C. Hinks; Ian D. Pavord; Stephen J. Fowler; Vanessa Brown; Lorcan P. McGarvey; Liam G. Heaney; Cary D. Austin; Peter Howarth; Joseph R. Arron; David F. Choy; Peter Bradding
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DIALOGUE maps multicellular programs in tissue from single-cell or spatial transcriptomics data
Nature Biotechnology, ISSN: 15461696 10870156
Livnat Jerby-Arnon; Aviv Regev
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The CRISPR Revolution in the Drug Discovery Workflow: An Industry Perspective
CRISPR Journal, ISSN: 25731602 25731599
Annalisa Lattanzi; Danilo Maddalo
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Entrectinib in children and young adults with solid or p y g,, aberrations (STARTRK-NG)
Neuro-Oncology, ISSN: 15228517
Ami V. Desai; Giles W. Robinson; Karen Gauvain; Ellen M. Basu; Margaret E. Macy; Luke Maese; Nicholas S. Whipple; Amit J. Sabnis; Jennifer H. Foster; Suzanne Shusterman; Janet Yoon; Brian D. Weiss; Mohamed S. Abdelbaki; Amy E. Armstrong; Thomas Cash; Christine A. Pratilas; Nadège Corradini; Lynley V. Marshall; Mufiza Farid-Kapadia; Saibah Chohan; Clare Devlin; Georgina Meneses-Lorente; Alison Cardenas; Katherine E. Hutchinson; Guillaume Bergthold; Hubert Caron; Edna Chow Maneval; Gajjar; Elizabeth Fox
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Western-Style Diet, pks Island-Carrying Escherichia coli, and Colorectal Cancer: Analyses From Two Large Prospective Cohort Studies
Gastroenterology, ISSN: 15280012 00165085
Kota Arima; Rong Zhong; Tomotaka Ugai; Melissa Zhao; Koichiro Haruki; Naohiko Akimoto; Mai Chan Lau; Kazuo Okadome; Raaj S. Mehta; Juha P. Väyrynen; Junko Kishikawa; Tyler S. Twombly; Shanshan Shi; Kenji Fujiyoshi; Keisuke Kosumi; Yoko Ogata; Hideo Baba; Fenglei Wang; Kana Wu; Mingyang Song; Xuehong Zhang; Charles Fuchs; Cynthia L. Sears; Walter C. Willett; Edward L. Giovannucci; Jeffrey A. Meyerhardt; Wendy S. Garrett; Curtis Huttenhower; Andrew T. Chan; Jonathan A. Nowak; Marios Giannakis; Shuji Ogino
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ABCL-073 Polatuzumab Vedotin Plus Rituximab, Cyclophosphamide, Doxorubicin, and Prednisone (Pola-R-CHP) Versus Rituximab, Cyclophosphamide, Doxorubicin, Vincristine and Prednisone (R-CHOP) Therapy in Patients With Previously Untreated Diffuse Large B-Cell Lymphoma (DLBCL): Results From the Phase III POLARIX Study
Clinical Lymphoma, Myeloma and Leukemia, ISSN: 21522669 21522650
Christopher R. Flowers; Herve Tilly; Morschhauser; Laurie H. Sehn; Jonathan W. Friedberg; Marek Trneny; Jeff P. Sharman; Charles Herbaux; John M. Burke; Matthew Matasar; Shinya Rai; Koji Izutsu; Neha Mehta-Shah; Lucie Oberic; Adrien Chauchet; Wojciech Jurczak; Yuqin Song; Greil; Larysa Mykhalska; Juan M. Bergua-Burgués; Matthew C. Cheung; Antonio Pinto; Ho-Jin Shin; Greg Hapgood; Eduardo Munhoz; Pau Abrisqueta; Jyh-Pyng Gau; Jamie Hirata; Yanwen Jiang; Mark Yan; Calvin Lee; Gilles Salles
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CLL-410 Adherence and Discontinuation Among Medicare Beneficiaries Initiating Venetoclax versus BTKis for Relapsed/Refractory Chronic Lymphocytic Leukemia
Clinical Lymphoma, Myeloma and Leukemia, ISSN: 21522669 21522650
Scott F Huntington; Beenish S. Manzoor; Justin T Puckett; Sachin Kamal-Bahl; Hasan Alhasani; Arliene Ravelo; Mahesh Fuldeore; Jalpa A Doshi
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IBCL-249 Mosunetuzumab Monotherapy Is an Effective and Well-Tolerated Treatment Option for Patients With Relapsed/Refractory (R/R) Follicular Lymphoma (FL) Who Have Received ≥2 Prior Lines of Therapy: Pivotal Results From a Phase I/II Study
Clinical Lymphoma, Myeloma and Leukemia, ISSN: 21522669 21522650
Elizabeth L Budde; Laurie H. Sehn; Matthew Matasar; Stephen J. Schuster; Sarit E. Assouline; Pratyush Giri; Kuruvilla; Miguel Canales; Sascha Dietrich; Keith Fay; Matthew Ku; Loretta J. Nastoupil; Michael C. Wei; Shen Yin; Michelle Y. Doral; Chi-Chung Li; Huang Huang; Raluca Negricea; Elicia M. Penuel; Carol E. O'Hear; Nancy L. Bartlett
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Genome-wide association study identifies kallikrein 5 in type 2 inflammation-low asthma
Journal of Allergy and Clinical Immunology, ISSN: 10976825 00916749
Janet Jackman; Amy Stockwell; David F. Choy; Markus M. Xie; Peipei Lu; Guiquan Jia; Hong Li; Abbas Alexander; Paola G. Bronson; Wei-Yu Lin; Cecilia P.C. Chiu; Henry R. Maun; Merone Roose-Girma; Lucinda Tam; Juan Zhang; Zora Modrusan; Robert R. Graham; Timothy Behrens; Steven R. White; Ted Naureckas; Carole Ober; Manuel A. R. Ferreira; Radislav Sedlacek; Jiansheng Wu; Wyne P. Lee; Robert A. Lazarus; James T. Koerber; Joseph R. Arron; Brian L. Yaspan; Tangsheng Yi
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CLL-410 Adherence and Discontinuation Among Medicare Beneficiaries Initiating Venetoclax versus BTKis for Relapsed/Refractory Chronic Lymphocytic Leukemia
Clinical Lymphoma, Myeloma and Leukemia, ISSN: 21522650
Scott F Huntington; Beenish S. Manzoor; Justin T Puckett; Sachin Kamal-Bahl; Hasan Alhasani; Arliene Ravelo; Mahesh Fuldeore; Jalpa A Doshi
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Determination of BET Specific Surface Area of Hydrate-Anhydrate Systems Susceptible to Phase Transformation Using Inverse Gas Chromatography
AAPS PharmSciTech, ISSN: 15309932
Minhthi Bui; Karthik Nagapudi; Paroma Chakravarty
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Drusen Characteristics and Age-Related Macular Degeneration in Fellow Eyes
Ophthalmology Retina, ISSN: 24686530
Caroline R. Baumal; Steven Blotner; Anne E. Fung; Carlos Quezada Ruiz
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ABCL-073 Polatuzumab Vedotin Plus Rituximab, Cyclophosphamide, Doxorubicin, and Prednisone (Pola-R-CHP) Versus Rituximab, Cyclophosphamide, Doxorubicin, Vincristine and Prednisone (R-CHOP) Therapy in Patients With Previously Untreated Diffuse Large B-Cell Lymphoma (DLBCL): Results From the Phase III POLARIX Study
Clinical Lymphoma, Myeloma and Leukemia, ISSN: 21522650
Christopher R. Flowers; Herve Tilly; Morschhauser; Laurie H. Sehn; Jonathan W. Friedberg; Marek Trneny; Jeff P. Sharman; Charles Herbaux; John M. Burke; Matthew Matasar; Shinya Rai; Koji Izutsu; Neha Mehta-Shah; Lucie Oberic; Adrien Chauchet; Wojciech Jurczak; Yuqin Song; Greil; Larysa Mykhalska; Juan M. Bergua-Burgués; Matthew C. Cheung; Antonio Pinto; Ho-Jin Shin; Greg Hapgood; Eduardo Munhoz; Pau Abrisqueta; Jyh-Pyng Gau; Jamie Hirata; Yanwen Jiang; Mark Yan; Calvin Lee; Gilles Salles
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IBCL-249 Mosunetuzumab Monotherapy Is an Effective and Well-Tolerated Treatment Option for Patients With Relapsed/Refractory (R/R) Follicular Lymphoma (FL) Who Have Received ≥2 Prior Lines of Therapy: Pivotal Results From a Phase I/II Study
Clinical Lymphoma, Myeloma and Leukemia, ISSN: 21522650
Elizabeth L Budde; Laurie H. Sehn; Matthew Matasar; Stephen J. Schuster; Sarit E. Assouline; Pratyush Giri; Kuruvilla; Miguel Canales; Sascha Dietrich; Keith Fay; Matthew Ku; Loretta J. Nastoupil; Michael C. Wei; Shen Yin; Michelle Y. Doral; Chi-Chung Li; Huang Huang; Raluca Negricea; Elicia M. Penuel; Carol E. O'Hear; Nancy L. Bartlett
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Direct Tie2 Agonists Stabilize Vasculature for the Treatment of Diabetic Macular Edema
Translational Vision Science and Technology, ISSN: 21642591
Nick Agard; Gu Zhang; John Ridgeway; Danielle DiCara; Phillip Y. Chu; Rachana Ohri; Sarah Sanowar; Jean-Michel Vernes; Hannah Chi; Jiameng Zhang; Emily Holz; Maciej Paluch; Guannan He; Yingjia Benson; Jianhuan Zhang; Pamela Chan; Nga Tang; Prachi Javale; Blair Wilson; Kathy Barrett; Rebecca K. Rowntree; Julie Hang; Y. Gloria Meng; Hass; Fuh; Robert Piskol; Vlad Bantseev; Kelly M. Loyet; John C. Tran; Cong Wu; Vahan B. Indjeian; Vittal Shivva; Minhong Yan
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Pharmacokinetics of the Port Delivery System with Ranibizumab in the Ladder Phase 2 Trial for Neovascular Age-Related Macular Degeneration
Ophthalmology and Therapy, ISSN: 21936528 21938245
Charles C. Wykoff; Peter A. Campochiaro; Dante Joseph Pieramici; Arshad M. Khanani; Shamika Gune; Mauricio Maia; Kagedal; Han Ting Ding; Katie F. Maass
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Activity and safety of ipatasertib (ipat) for AKT activating mutation and/ or PTEN loss/loss of function solid tumors from MyTACTIC
European Journal of Cancer, ISSN: 09598049
Ari VanderWalde; David Spigel; Darbonne; Yu; Kim; Whitehead; Szado; Slater; Zuniga; Arrowsmith
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Direct Tie2 Agonists Stabilize Vasculature for the Treatment of Diabetic Macular Edema
Translational Vision Science and Technology,
Nick Agard; Gu Zhang; John Ridgeway; Danielle DiCara; Phillip Y. Chu; Rachana Ohri; Sarah Sanowar; Jean-Michel Vernes; Hannah Chi; Jiameng Zhang; Emily Holz; Maciej Paluch; Guannan He; Yingjia Benson; Jianhuan Zhang; Pamela Chan; Nga Tang; Prachi Javale; Blair Wilson; Kathy Barrett; Rebecca K. Rowntree; Julie Hang; Y. Gloria Meng; Hass; Fuh; Robert Piskol; Vlad Bantseev; Kelly M. Loyet; John C. Tran; Cong Wu; Vahan B. Indjeian; Vittal Shivva; Minhong Yan
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Western-Style Diet, pks Island-Carrying Escherichia coli, and Colorectal Cancer: Analyses From Two Large Prospective Cohort Studies
Gastroenterology, ISSN: 00165085
Kota Arima; Rong Zhong; Tomotaka Ugai; Melissa Zhao; Koichiro Haruki; Naohiko Akimoto; Mai Chan Lau; Kazuo Okadome; Raaj S. Mehta; Juha P. Väyrynen; Junko Kishikawa; Tyler S. Twombly; Shanshan Shi; Kenji Fujiyoshi; Keisuke Kosumi; Yoko Ogata; Hideo Baba; Fenglei Wang; Kana Wu; Mingyang Song; Xuehong Zhang; Charles Fuchs; Cynthia L. Sears; Walter C. Willett; Edward L. Giovannucci; Jeffrey A. Meyerhardt; Wendy S. Garrett; Curtis Huttenhower; Andrew T. Chan; Jonathan A. Nowak; Marios Giannakis; Shuji Ogino
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Development of a pediatric physiologically-based pharmacokinetic model to support recommended dosing of atezolizumab in children with solid tumors
Frontiers in Pharmacology, ISSN: 16639812
Weize Huang; Felix Stader; Phyllis Chan; Colby S. Shemesh; Yuan Chen; Katherine L. Gill; Hannah M. Jones; Linzhong Li; Gianluca Rossato; Benjamin Wu; Jin Y. Jin; Pascal Chanu
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Development of a pediatric physiologically-based pharmacokinetic model to support recommended dosing of atezolizumab in children with solid tumors
Frontiers in Pharmacology,
Weize Huang; Felix Stader; Phyllis Chan; Colby S. Shemesh; Yuan Chen; Katherine L. Gill; Hannah M. Jones; Linzhong Li; Gianluca Rossato; Benjamin Wu; Jin Y. Jin; Pascal Chanu
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Giredestrant reverses progesterone hypersensitivity driven by estrogen receptor mutations in breast cancer
Science Translational Medicine, ISSN: 19466242 19466234
Jackson Liang; Ellen Ingalla; Xiaosai Yao; Bu-Er Wang; Lisa Tai; Jennifer M. Giltnane; Yuxin Liang; Anneleen Daemen; Heather M. Moore; Junko Aimi; Ching-Wei Chang; Mary R. Gates; Jennifer Eng-Wong; Lucinda Tam; Natasha Bacarro; Merone Roose-Girma; Meritxell Bellet; Marc Hafner; Ciara Metcalfe
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Giredestrant reverses progesterone hypersensitivity driven by estrogen receptor mutations in breast cancer
Science Translational Medicine, ISSN: 19466242
Jackson Liang; Ellen Ingalla; Xiaosai Yao; Bu-Er Wang; Lisa Tai; Jennifer M. Giltnane; Yuxin Liang; Anneleen Daemen; Heather M. Moore; Junko Aimi; Ching-Wei Chang; Mary R. Gates; Jennifer Eng-Wong; Lucinda Tam; Natasha Bacarro; Merone Roose-Girma; Meritxell Bellet; Marc Hafner; Ciara Metcalfe
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Giredestrant reverses progesterone hypersensitivity driven by estrogen receptor mutations in breast cancer
Science Translational Medicine,
Jackson Liang; Ellen Ingalla; Xiaosai Yao; Bu-Er Wang; Lisa Tai; Jennifer M. Giltnane; Yuxin Liang; Anneleen Daemen; Heather M. Moore; Junko Aimi; Ching-Wei Chang; Mary R. Gates; Jennifer Eng-Wong; Lucinda Tam; Natasha Bacarro; Merone Roose-Girma; Meritxell Bellet; Marc Hafner; Ciara Metcalfe
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Deletion of a previously uncharacterized lipoprotein lirL confers resistance to an inhibitor of type II signal peptidase in Acinetobacter baumannii
Proceedings of the National Academy of Sciences of the United States of America,
Ke-Jung Huang; Homer Pantua; Jingyu Diao; Elizabeth Skippington; Michael Volny; Wendy N. Sandoval; Varnesh Tiku; Yutian Peng; Meredith Sagolla; Donghong Yan; Jing Kang; Anand K. Katakam; Nairie Michaelian; Mike Reichelt; Man-Wah Tan; Cary D. Austin; Min Xu; Emily J. Hanan; Sharookh B. Kapadia
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Analysis of therapeutic nucleic acids by capillary electrophoresis
Journal of Pharmaceutical and Biomedical Analysis, ISSN: 07317085
Bingchuan Wei; Alexandre Goyon; Kelly Zhang
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Analysis of therapeutic nucleic acids by capillary electrophoresis
Journal of Pharmaceutical and Biomedical Analysis, ISSN: 1873264X 07317085
Bingchuan Wei; Alexandre Goyon; Kelly Zhang
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Deletion of a previously uncharacterized lipoprotein lirL confers resistance to an inhibitor of type II signal peptidase in Acinetobacter baumannii
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 10916490 00278424
Ke-Jung Huang; Homer Pantua; Jingyu Diao; Elizabeth Skippington; Michael Volny; Wendy N. Sandoval; Varnesh Tiku; Yutian Peng; Meredith Sagolla; Donghong Yan; Jing Kang; Anand K. Katakam; Nairie Michaelian; Mike Reichelt; Man-Wah Tan; Cary D. Austin; Min Xu; Emily J. Hanan; Sharookh B. Kapadia
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Assessment of KRAS G12C Target Engagement by a Covalent Inhibitor in Tumor Biopsies Using an Ultra-Sensitive Immunoaffinity 2D-LC-MS/MS Approach
Analytical Chemistry, ISSN: 15206882 00032700
Lingyao Meng; Emily W. Chan; Carl Ng; Junko Aimi; John C. Tran; Angela J. Oh; Mark Merchant; Hans E. Purkey; Timothy P. Heffron; Surinder Kaur; Keyang Xu; Zhen Shi; Jintang He
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Nonclinical Pharmacokinetics, Pharmacodynamics, and Translational Model of RO7297089, A Novel Anti-BCMA/CD16A Bispecific Tetravalent Antibody for the Treatment of Multiple Myeloma
AAPS Journal,
Hao Cai; Satoko Kakiuchi-Kiyota; Robert Hendricks; Shelly Zhong; Luna Liu; Adedeji; Pamela Chan; Melissa Schutten; Amrita Kamath; Meric A. Ovacik
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Clinico-Genomic Characterization of Patients with Metastatic Urothelial Carcinoma in Real-World Practice Identifies a Novel Bladder Immune Performance Index (BIPI)
Clinical Cancer Research,
Bernadett Szabados; Mariano Ponz-Sarvisé; Robson Machado; Diego Saldana; Edward E. Kadel III; Romain Banchereau; Fanny Bouquet; Marius Garmhausen; Thomas Powles; Carsten Schröder
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Clinico-Genomic Characterization of Patients with Metastatic Urothelial Carcinoma in Real-World Practice Identifies a Novel Bladder Immune Performance Index (BIPI)
Clinical Cancer Research, ISSN: 15573265
Bernadett Szabados; Mariano Ponz-Sarvisé; Robson Machado; Diego Saldana; Edward E. Kadel III; Romain Banchereau; Fanny Bouquet; Marius Garmhausen; Thomas Powles; Carsten Schröder
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NKG2A and HLA-E define an alternative immune checkpoint axis in bladder cancer
Cancer Cell, ISSN: 18783686 15356108
Bérengère Salomé; John P. Sfakianos; Daniel Ranti; Jorge Daza; Christine Bieber; Andrew Charap; Christian Hammer; Romain Banchereau; Adam M. Farkas; Dan Fu Ruan; Sudeh Izadmehr; Daniel Geanon; Geoffrey Kelly; Ronaldo M. de Real; Brian Lee; Kristin G. Beaumont; Sanjana Shroff; Yuanshuo A. Wang; Ying-chih Wang; Tin Htwe Thin; Monica Garcia-Barros; Everardo Hegewisch-Solloa; Emily M. Mace; Li Wang; Timothy O'Donnell; Diego Chowell; Ruben Fernandez-Rodriguez; Mihaela Skobe; Nicole Taylor; Seunghee Kim-Schulze; Robert Sebra; Doug Palmer; Eleanor Clancy-Thompson; Scott A. Hammond; Alice O. Kamphorst; Karl-Johan Malmberg; Emanuela Marcenaro; Pedro Romero; Rachel Brody; Mathias Viard; Yuko Yuki; Maureen Martin; Mary Carrington; Reza Mehrazin; Peter Wiklund; Ira Mellman; Sanjeev Mariathasan; Jun Zhu; Matthew D. Galsky; Nina Bhardwaj; Amir Horowitz
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NKG2A and HLA-E define an alternative immune checkpoint axis in bladder cancer
Cancer Cell, ISSN: 15356108
Bérengère Salomé; John P. Sfakianos; Daniel Ranti; Jorge Daza; Christine Bieber; Andrew Charap; Christian Hammer; Romain Banchereau; Adam M. Farkas; Dan Fu Ruan; Sudeh Izadmehr; Daniel Geanon; Geoffrey Kelly; Ronaldo M. de Real; Brian Lee; Kristin G. Beaumont; Sanjana Shroff; Yuanshuo A. Wang; Ying-chih Wang; Tin Htwe Thin; Monica Garcia-Barros; Everardo Hegewisch-Solloa; Emily M. Mace; Li Wang; Timothy O'Donnell; Diego Chowell; Ruben Fernandez-Rodriguez; Mihaela Skobe; Nicole Taylor; Seunghee Kim-Schulze; Robert Sebra; Doug Palmer; Eleanor Clancy-Thompson; Scott A. Hammond; Alice O. Kamphorst; Karl-Johan Malmberg; Emanuela Marcenaro; Pedro Romero; Rachel Brody; Mathias Viard; Yuko Yuki; Maureen Martin; Mary Carrington; Reza Mehrazin; Peter Wiklund; Ira Mellman; Sanjeev Mariathasan; Jun Zhu; Matthew D. Galsky; Nina Bhardwaj; Amir Horowitz
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Turning the Other Cheek: Influence of the cis-Tetrafluorocyclohexyl Motif on Physicochemical and Metabolic Properties
ACS Medicinal Chemistry Letters, ISSN: 19485875
Yong Wang; Wendy Lee; Yi-Chen Chen; Yuhui Zhou; Emile G. Plise; Madyson M. Migliozzi; James J. Crawford
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Structural basis for SHOC2 modulation of RAS signalling
Nature, ISSN: 14764687 00280836
Nicholas P. D. Liau; Matthew C. Johnson; Saeed Izadi; Luca Gerosa; Michal Hammel; John M. Bruning; Timothy J. Wendorff; Wilson Phung; Sarah G. Hymowitz; Jawahar Sudhamsu
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Attribute Analytics Performance Metrics from the MAM Consortium Interlaboratory Study
Journal of the American Society for Mass Spectrometry, ISSN: 18791123 10440305
Trina Mouchahoir; John Schiel; Richard S. Rogers; Alan Heckert; Benjamin J. Place; Aaron Ammerman; Xiaoxiao Li; Tom Robinson; Brian Schmidt; Chris M. Chumsae; Xinbi Li; Anton V. Manuilov; Bo Yan; Gregory O. Staples; Da Ren; Alexander J. Veach; Dongdong Wang; Wael Yared; Zoran Sosic; Yan Wang; Li Zang; Anthony M. Leone; Peiran Liu; Richard Ludwig; Li Tao; Wei Wu; Ahmet Cansizoglu; Andrew Hanneman; Greg W. Adams; Irina Perdivara; Hunter Walker; Margo Wilson; Arnd Brandenburg; Nick Degraan-Weber; Stefano Gotta; Joe Shambaugh; Melissa Alvarez; X. Christopher Yu; Li Cao; Chun Shao; Andrew Mahan; Hirsh Nanda; Kristen Nields; Nancy Nightlinger; Ben Niu; Jihong Wang; Wei Xu; Gabriella Leo; Nunzio Sepe; Yan-Hui Liu; Bhumit A. Patel; Douglas D. Richardson; Yi Wang; Daniela Tizabi; Oleg V. Borisov; Yali Lu; Ernest L. Maynard; Albrecht Gruhler; Kim F. Haselmann; Thomas N. Krogh; Carsten P. Sönksen; Simon Letarte; Sean Shen; Kristin Boggio; Keith Johnson; Wenqin Ni; Himakshi Patel; David Ripley; Jason C. Rouse; Ying Zhang; Carly Daniels; Andrew Dawdy; Olga Friese; Thomas W. Powers; Justin B. Sperry; Josh Woods; Eric Carlson; K. Ilker Sen; St John Skilton; Michelle Busch; Anders Lund; Martha Stapels; Xu Guo; Sibylle Heidelberger; Harini Kaluarachchi; Sean Mccarthy; John Kim; Jing Zhen; Ying Zhou; Sarah Rogstad; Xiaoshi Wang; Jing Fang; Weibin Chen; Ying Qing Yu; John G. Hoogerheide; Rebecca Scott; Hua Yuan
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A WISP1 antibody inhibits MRTF signaling to prevent the progression of established liver fibrosis
Cell Metabolism, ISSN: 19327420 15504131
Ying Xi; Ryan LaCanna; Hsiao-Yen Ma; Elsa N. N'Diaye; Sarah Gierke; Patrick Caplazi; Meredith Sagolla; Zhiyu Huang; Laura Lucio; Alexander Arlantico; Surinc Er Jeet; Hans D. Brightbill; Claire Emson; Aaron Wong; Katrina B. Morshead; Daryle J. DePianto; Merone Roose-Girma; Charles Yu; Lucinda Tam; Guiquan Jia; Thirumalai R. Ramalingam; Scot A. Marsters; Avi Ashkenazi; Si Hyun Kim; Ryan Kelly; Shuang Wu; Paul J. Wolters; Ariel E. Feldstein; Jason A. Vander Heiden; Ning Ding
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A WISP1 antibody inhibits MRTF signaling to prevent the progression of established liver fibrosis
Cell Metabolism,
Ying Xi; Ryan LaCanna; Hsiao-Yen Ma; Elsa N. N'Diaye; Sarah Gierke; Patrick Caplazi; Meredith Sagolla; Zhiyu Huang; Laura Lucio; Alexander Arlantico; Surinc Er Jeet; Hans D. Brightbill; Claire Emson; Aaron Wong; Katrina B. Morshead; Daryle J. DePianto; Merone Roose-Girma; Charles Yu; Lucinda Tam; Guiquan Jia; Thirumalai R. Ramalingam; Scot A. Marsters; Avi Ashkenazi; Si Hyun Kim; Ryan Kelly; Shuang Wu; Paul J. Wolters; Ariel E. Feldstein; Jason A. Vander Heiden; Ning Ding
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Sources of Cancer Neoantigens beyond Single-Nucleotide Variants
International Journal of Molecular Sciences, ISSN: 14220067
Aude-Hélène Capietto; Reyhane Hoshyar; Lélia Delamarre
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Sources of Cancer Neoantigens beyond Single-Nucleotide Variants
International Journal of Molecular Sciences,
Aude-Hélène Capietto; Reyhane Hoshyar; Lélia Delamarre
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Complementary Roles for Tissue- and Blood-Based Comprehensive Genomic Profiling for Detection of Actionable Driver Alterations in Advanced NSCLC
JTO Clinical and Research Reports, ISSN: 26663643
Lee S. Schwartzberg; Gerald Li; Khaled Tolba; Ariel B. Bourla; Katja Schulze; Rujuta Gadgil; Alexander Fine; Katherine T. Lofgren; Ryon P. Graf; Geoffrey R. Oxnard; Davey B Daniel
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IAP antagonist GDC-0917 is more potent than Debio1143 in promoting cell death, c-IAP1 degradation and tumor growth inhibition
Cell Death and Disease, ISSN: 20414889
Bruno Alicke; Eugene Varfolomeev; Shi Hui Kaylee Lee; Alexandra Frommlet; Savita Ubhayakar; John G. Quinn; Wayne J. Fairbrother; Robert Jones; Stephen Gould; Domagoj Vucic
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Physiologically Based Pharmacokinetic Models Can Be Used to Predict the Unique Nonlinear Absorption Profiles of Vismodegib
Drug Metabolism and Disposition, ISSN: 1521009X 00909556
Louis Lin; Matthew Wright; Cornelis E. Hop; Harvey Wong
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Complementary Roles for Tissue- and Blood-Based Comprehensive Genomic Profiling for Detection of Actionable Driver Alterations in Advanced NSCLC
JTO Clinical and Research Reports,
Lee S. Schwartzberg; Gerald Li; Khaled Tolba; Ariel B. Bourla; Katja Schulze; Rujuta Gadgil; Alexander Fine; Katherine T. Lofgren; Ryon P. Graf; Geoffrey R. Oxnard; Davey B Daniel
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Hydroxypropyl methyl cellulose derivatives stabilize fragment antibody against aggregation in spray dried formulations at elevated temperature and resist pH changes
European Journal of Pharmaceutics and Biopharmaceutics, ISSN: 18733441 09396411
Purnendu K. Nayak; Karthikan Rajagopal; Debby P. Chang
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Exacerbation Profile and Risk Factors in a Type-2-Low Enriched Severe Asthma Cohort A Clinical Trial to Assess Asthma Exacerbation Phenotypes
American Journal of Respiratory and Critical Care Medicine, ISSN: 15354970 1073449X
Pamela Jane McDowell; John Busby; Catherine E. Hanratty; Ratko Djukanovic; Ashley Woodcock; Samantha Walker; Tim Hardman; Joseph R. Arron; David F. Choy; Peter Bradding; Chris E. Brightling; Rekha Chaudhuri; Douglas Cowan; Adel Mansur; Stephen J. Fowler; Sarah Diver; Peter Howarth; James Lordan; Andrew Menzies-Gow; Timothy Harrison; Douglas S. Robinson; Cécile T.J. Holweg; Matthews; Ian D. Pavord; Liam G. Heaney; Martyn Partridge; Mike Morgan; Anne Millar; Mark Stafford-Watson; Gabriella Cooper
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