Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 51 - 100 OF 10835 RESULTS

Pirfenidone reduces respiratory-related hospitalizations in idiopathic pulmonary fibrosis
American Journal of Respiratory and Critical Care Medicine, ISSN: 1073449X
Brett Ley; Jeffrey J. Swigris; Bann-mo Day; John L. Stauffer; Karina Raimundo; Willis Chou; Harold R. Collard
Single-cell dynamics determines response to CDK4/6 inhibition in triple-negative breast cancer
Clinical Cancer Research, ISSN: 10780432
Uzma S. Asghar; Alexis R. Barr; Rosalind J. Cutts; Matthew Beaney; Irina Babina; Deepak Sampath; Jennifer Giltnane; Jennifer Lacap; Lisa Crocker; Amy Young; Alex Pearson; Maria Teresa Herrera-Abreu; Chris Bakal; Nicholas C. Turner
Design of Selective Benzoxazepin PI3Kδ Inhibitors Through Control of Dihedral Angles
ACS Medicinal Chemistry Letters,
Brian Safina; Richard Elliott; Andrew K. Forrest; Robert Heald; Jeremy Murray; Jim Nonomiya; Jodie Pang; Laurent Salphati; Eileen M. Seward; Steven Staben; Mark Ultsch; Binqing Wei; Wenqian Yang; Dan Sutherlin
Protein engineering to increase the potential of a therapeutic antibody Fab for long-acting delivery to the eye
mAbs, ISSN: 19420862
Devin Tesar; Jacob Luoma; Emily A. Wyatt; Catherine Shi; Whitney Shatz; Phil Hass; Mary Mathieu; Li Yi; Jacob E. Corn; Katie F. Maass; Kathryn Wang; Michelle Z. Dion; Nisana Andersen; Kelly Loyet; Menno van Lookeren Campagne; Karthik Rajagopal; Leslie Dickmann; Justin Scheer; Robert F. Kelley
Randomized phase III trial of trastuzumab plus capecitabine with or without pertuzumab in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer who experienced disease progression during or after trastuzumab-based therapy
Journal of Clinical Oncology, ISSN: 0732183X
Ander Urruticoechea; Mohammed Rizwanullah; Seock-Ah Im; Antonio Carlos Sánchez Ruiz; István Láng; Gianluca Tomasello; Hannah Douthwaite; Tanja Badovinac Crnjevic; Sarah Heeson; Jennifer Eng-Wong; Montserrat Muñoz
Journal of the American Chemical Society, ISSN: 15205126 00027863
Kyle A. Mack; Andrew McClory; Haiming Zhang; Francis Gosselin; David B. Collum
Autophagy, ISSN: 15548635 15548627
Marianne R. Spalinger; Silvia Lang; Claudia Gottier; Xuezhi Dai; David J. Rawlings; Andrew C. Chan; Gerhard Rogler; Michael Scharl
Lung Cancer, ISSN: 18728332 01695002
Lukas Bubendorf; Urania Dafni; Martin Schöbel; Stephen P. Finn; Verena Tischler; Aleksandra Sejda; Antonio Marchetti; Erik Thunnissen; Eric K. Verbeken; Arne Warth; Irene Sansano; Richard Cheney; Ernst Jan M. Speel; Daisuke Nonaka; Kim Monkhorst; Henrik Hager; Miguel Martorell; Spasenija Savic; Keith M. Kerr; Qiang Tan; Zoi Tsourti; Thomas R. Geiger; Roswitha Kammler; Katja Schulze; Ashis Das-Gupta; David Shames; Solange Peters; Rolf A Stahel
Protein Engineering, Design and Selection, ISSN: 17410134 17410126
Mark Ultsch; Andrew Charles Braisted; Henry Maun; Charles Eigenbrot
Respiration, ISSN: 14230356 00257931
Ulrich Costabel; Carlo Albera; Lisa H Lancaster; Chin-Yu Lin; Philip Hormel; Henry N. Hulter; Paul W Noble
Protein Engineering, Design and Selection, ISSN: 17410134 17410126
Hok Seon Kim; Diana Ronai Dunshee; Angie Yee; Raymond Tong; Ingrid Kim; Farzam Farahi; Jo-Anne Hongo; James Ernst; Jun Sonoda; Christoph Spiess
A phase ib dose-escalation study of the safety, tolerability, and pharmacokinetics of cobimetinib and duligotuzumab in patients with previously treated locally advanced ormetastatic cancers with mutant KRAS
Oncologist, ISSN: 10837159
Christopher H. Lieu; Manuel Hidalgo; Jordan Berlin; Andrew H. Ko; Andrés Cervantes; Patricia M. LoRusso; David E. Gerber; Paul Eder; Gail Eckhardt; Amy Kapp; Amy Tsuhako; Bruce McCall; Andrea Pirzkall; Anne Uyei; Tabernero
Cotargeting of MEK and PDGFR/STAT3 pathways to treat pancreatic ductal adenocarcinoma
Molecular Cancer Therapeutics, ISSN: 15357163
Nisebita Sahu; Emily Chan; Felix Chu; Thinh Pham; Hartmut Koeppen; Bill Forrest; Mark Merchant; Jeffrey Settleman
Gene expression profiling in BRAF-mutated melanoma reveals patient subgroups with poor outcomes to vemurafenib that may be overcome by cobimetinib plus vemurafenib
Clinical Cancer Research, ISSN: 10780432
Matthew Wongchenko; Grant A. McArthur; Brigitte Dréno; James Larkin; Paolo A. Ascierto; Jeffrey A. Sosman; Luc Andries; Mark Kockx; Stephen D. Hurst; Ivor Caro; Isabelle Rooney; Priti Hegde; Luciana Molinero; Huibin Yue; Ilsung Chang; Lukas Amler; Yibing Yan; Antoni Ribas
Veterinary Pathology, ISSN: 15442217 03009858
Cindy A. Farman; Chris Schuetz; Florence Lorget; Vladimir Bantseev; David Calise; Evan Thackaberry
Vision-related functional burden of diabetic retinopathy across severity levels in the United States
JAMA Ophthalmology, ISSN: 21686165
Jeffrey R. Willis; Quan V. Doan; Michelle Gleeson; Zdenka Haskova; Pradeep Ramulu; Lawrence S. Morse; Ronald Cantrell
Advances in Therapy, ISSN: 18658652 0741238X
Lin Pan; Paula Belloni; Han Ting Ding; Jianshuang Wang; Christopher M. Rubino; Wendy Putnam
Nature Genetics, ISSN: 15461718 10614036
Rebecca Sims; Sven J. Van Der Lee; Adam C. Naj; Celine Bellenguez; Nandini Badarinarayan; Johanna Jakobsdottir; Brian W. Kunkle; Anne Boland; Rachel Raybould; Joshua C. Bis; Eden R. Martin; Benjamin Grenier-Boley; Stefanie Heilmann-Heimbach; Vincent Chouraki; Amanda B. Kuzma; Kristel Sleegers; Maria Vronskaya; Agustin Ruiz; Robert R. Graham; Robert Olaso; Per Hoffmann; Megan L. Grove; Badri N. Vardarajan; Mikko Hiltunen; Markus M. Nöthen; Charles C. White; Kara L. Hamilton-Nelson; Jacques Epelbaum; Wolfgang Maier; Seung-Hoan Choi; Gary W. Beecham; Cécile Dulary; Stefan Herms; Albert V. Smith; Cory C. Funk; Céline Derbois; Andreas J. Forstner; Shahzad Ahmad; Hongdong Li; Delphine Bacq; Denise Harold; Claudia L. Satizabal; Otto Valladares; Alessio Squassina; Rhodri Thomas; Jennifer Brody; Liming Qu; Pascual Sánchez-Juan; Taniesha Morgan; Frank J Wolters; Yi Zhao; Florentino Sanchez Garcia; Nicola Denning; Myriam Fornage; John Malamon; Maria Candida Deniz Naranjo; Elisa Majounie; Thomas H Mosley; Beth A. Dom
New England Journal of Medicine, ISSN: 15334406 00284793
Johannes Oldenburg; Johnny N. Mahlangu; Benjamin Kim; Christophe Schmitt; Michael U. Callaghan; Guy Young; Elena Santagostino; Rebecca Krusejarres; Claude Negrier; Craig Kessler; Nancy Valente; Elina Asikanius; Gallia G. Levy; Jerzy Windyga; Midori Shima
Nature, ISSN: 14764687 00280836
Mohamed Lamkanfi; Vishva Dixit
AAPS Journal, ISSN: 15507416
Andre Hermans; Andreas M. Abend; Filippos Kesisoglou; Talia Flanagan; Michael J. Cohen; Dorys A. Diaz; Mao; Limin Zhang; Gregory K. Webster; Yiqing Lin; David Hahn; Carrie A. Coutant; Haiyan Grady
Journal of Clinical Oncology, ISSN: 15277755 0732183X
Solange Peters; Scott Gettinger; Melissa L. Johnson; Pasi A. Jänne; Marina C. Garassino; Daniel Christoph; Chee Keong Toh; Naiyer A. Rizvi; Jamie E. Chaft; Enric Carcereny Costa; Jyoti D. Patel; Laura Q.M. Chow; Marianna Koczywas; Cheryl Ho; Martin Früh; Michel Van Den Heuvel; Jeffrey Rothenstein; Martin Reck; Luis Paz-Ares; Frances A. Shepherd; Takayasu Kurata; Zhengrong Li; Jiaheng Qiu; Marcin Kowanetz; Simonetta Mocci; Geetha Shankar; Alan Sandler; Enriqueta Felip
Bioconjugate Chemistry, ISSN: 15204812 10431802
Jack Sadowsky; Thomas Pillow; Jinhua Chen; Fang Fan; Changrong He; Yanli Wang; Gang Yan; Hui Yao; Zijin Xu; Shanique Martin; Donglu Zhang; Phillip Chu; Josefa Dela Cruz Chuh; Aimee O'Donohue; Ginny (Guangmin) Li; Geoff Del Rosario; Jintang He; Luna Liu; Carl Ng; Dian Su; Gail Phillips; Kathy Kozak; Shang-Fan Yu; Keyang Xu; Douglas Leipold; John Wai
Science Translational Medicine, ISSN: 19466242 19466234
Claire Le Pichon; Bill Meilandt; Sara Dominguez; Hilda Solanoy; Han Lin; Hai Ngu; Alvin Gogineni; Arundhati Sengupta Ghosh; Zhiyu Jiang; Seung-Hye Lee; Janice Maloney; Vineela Gandham; Christine Pozniak; Bei Wang; Sebum Lee; Mike Siu; Snahel Patel; Zora Modrusan; Xingrong Liu; York Rudhard; Miriam Baca; Amy Gustafson; Josh Kaminker; Rick Carano; Eric J. Huang; Oded Foreman; Robby Weimer; Kimberly Scearce-Levie; Joe Lewcock
Pharmaceutical Research, ISSN: 1573904X 07248741
Jialin Mao; Peter Fan; Susan Wong; Jonathan Wang; Moulay Hicham Alaoui Ismaili; Brian Dean; Marcel Hop; Matthew Wright; Yuan Chen
Journal of Immunology, ISSN: 15506606 00221767
Jonathan Sitrin; Eric Suto; Arthur Wuster; Jeff Eastham Anderson; Jeong Kim; Cary Austin; Wyne Lee; Tim Behrens
Cancer Cell, ISSN: 18783686 15356108
Gulfem Guler; Charles Tindell; Bob Pitti; Catherine Wilson; Katrina Nichols; Tommy KaiWai Cheung; Hyo-jin Kim; Matthew Wongchenko; Yibing Yan; Benjamin Haley; Trinna Cuellar; Webster; Navneet Alag; Ganapati Hegde; Erica Jackson; Tracy Leah Nance; Paul Garrett Giresi; Kuan-Bei Chen; Jinfeng Liu; Suchit Jhunjhunwala; Jeffrey Settleman; Jean-Philippe Stephan; David Arnott; Marie Classon
Health and Quality of Life Outcomes, ISSN: 14777525
Mark S. Walker; Wong; Arliene Ravelo; Paul J. E. Miller; Lee S. Schwartzberg
Advancements in Understanding Immunogenicity of Biotherapeutics in the Intraocular Space
AAPS Journal,
Eric Wakshull; Valerie Quarmby; Hanns-Christian Mahler; Hongwen Rivers; Dhananjay Jere; Meg Ramos; Piotr Szczesny; Karoline Bechtold-Peters; Sharmila Masli; Swati Gupta
Highly Stereoselective Synthesis of Tetrasubstituted Acyclic All-Carbon Olefins via Enol Tosylation and Suzuki-Miyaura Coupling
Journal of the American Chemical Society, ISSN: 00027863
Beryl X. Li; Diane N. Le; Kyle A. Mack; Andrew McClory; Ngiap-Kie Lim; Theresa Cravillion; Scott Savage; Chong Han; David B. Collum; Haiming Zhang; Francis Gosselin
Introduction of Trifluoroethylamine as Amide Isostere by C-H Functionalization of Heteroarenes
Organic Letters, ISSN: 15237060
Marie-Gabrielle Braun; Georgette Castanedo; Ling Qin; Patrick Salvo; Samir Z. Zard
Journal of Clinical Oncology, ISSN: 15277755 0732183X
Manish A. Shah; Rui-hua Xu; Yung-Jue Bang; Paulo M. Hoff; Tianshu Liu; Luis A. Herráez-Baranda; Fan Xia; Amit Garg; Mona Shing; Tabernero
Nuclear Medicine and Biology, ISSN: 18729614
Tang Tang; Herman Gill; Annie Ogasawara; Jeff Tinianow; Alex Vanderbilt; Simon Williams; Georgia Hatzivassiliou; Sharla White; Wendy Sandoval; Kevin DeMent; Mengling Wong; Jan Marik
European Journal of Pharmaceutics and Biopharmaceutics, ISSN: 18733441
Ajit Narang; Anand Balakrishnan; John Morrison; Jinjiang Li; Jennifer Wang; Huidong Gu; Katrina Taylor; Kenneth Santone; Jon Ehrmann; Sophie Beyer; Xujin Lu; Rod Ketner; Jennifer Pizzano; Tami Orcutt; Eric Shields; Heidi Dulac; Sharon Aborn; Margaret Batchelder; Kimberley Lentz
Investigative Ophthalmology and Visual Science, ISSN: 15525783 01460404
Evan Thackaberry; Cindy A. Farman; Fiona Zhong; Florence Lorget; Karin Staflin; Angelique Cercillieux; Paul E. Miller; Chris Schuetz; Debby Chang; Amin Famili; Ann Daugherty; Karthik Rajagopal; Vladimir Bantseev
Bioanalysis, ISSN: 17576199 17576180
Kathi Williams; Rich Erickson; Sally Fischer
SNP-mediated disruption of CTCF binding at the IFITM3 promoter is associated with risk of severe influenza in humans
Nature Medicine, ISSN: 10788956
Emma Kaitlynn Allen; Adrienne G. Randolph; Tushar Bhangale; Pranay Dogra; Maikke B. Ohlson; Christine M. Oshansky; Anthony E. Zamora; John P. Shannon; David Finkelstein; Amy Dressen; John DeVincenzo; Miguela Caniza; Ben Youngblood; Carrie Rosenberger; Paul G. Thomas
Journal of Experimental Medicine, ISSN: 15409538 00221007
Arturo I. Machuca-Parra; Alexander A. Bigger-Allen; Angie V. Sanchez; Anissa Boutabla; Jonathan Cardona-Vélez; Dhanesh Amarnani; Magali Saint-Geniez; Chris Siebel; Leo A. Kim; Patricia A. D'Amore; Joseph F. Arboleda-Velasquez
Archives of Toxicology, ISSN: 14320738 03405761
Will Proctor; Alison J. Foster; Jennifer Vogt; Claire Summers; Brian Middleton; Mark A. Pilling; Daniel Shienson; Monika Kijanska; Simon Ströbel; Jens M. Kelm; Paul Morgan; Simon Messner; Dominic Williams
Current Opinion in Structural Biology, ISSN: 1879033X
Thomas Clairfeuille; Hui Xu; Chris Koth; Jian Payandeh
A phase 1, randomized, double-blind, placebo-controlled, single-ascending-dose study to investigate the safety, tolerability, and pharmacokinetics of an anti-influenza B virus monoclonal antibody, MHAB5553A, in healthy volunteers
Antimicrobial Agents and Chemotherapy, ISSN: 00664804
Jeremy Lim; Michael Derby; Yaping Zhang; Rong Deng; Richard Larouche; Malia Anderson; Mauricio Maia; Stephanie Carrier; Isabelle Pelletier; Johanne Girard; Priya Kulkarni; Elizabeth Newton; Jorge Tavel
Journal of the American Society for Mass Spectrometry, ISSN: 18791123
E. Ellen Jones; Cristine Quiason-Huynh; Stephanie Dale; Sheerin Latham
Multiplexed ion beam imaging analysis for quantitation of protein expresssion in cancer tissue sections
Laboratory Investigation, ISSN: 00236837
Sandra Rost; Jennifer Giltnane; Jennifer M. Bordeaux; Chuck Hitzman; Hartmut Koeppen; Scot D. Liu
SeqArray-a storage-efficient high-performance data format for WGS variant calls
Bioinformatics, ISSN: 13674803
Xiuwen Zheng; Stephanie M. Gogarten; Michael Lawrence; Adrienne Stilp; Matthew P. Conomos; Bruce S. Weir; Cathy C. Laurie; David Levine
Nature Reviews Drug Discovery, ISSN: 14741784 14741776
John Moffat; Fabien Vincent; Jonathan A. Lee; Jörg Eder; Marco Prunotto
Effect of Aggregation on the Hydrodynamic Properties of Bovine Serum Albumin
Pharmaceutical Research, ISSN: 07248741
Masha Pindrus; James L. Cole; Japneet Kaur; Steve Shire; Sandeep Yadav; Devendra S. Kalonia
Sustainable Practices in Medicinal Chemistry Part 2: Green by Design
Journal of Medicinal Chemistry, ISSN: 00222623
Ignacio Aliagas; Raphaëlle Berger; Kristin Goldberg; Rachel T. Nishimura; John Reilly; Paul Richardson; Daniel Richter; Edward C. Sherer; Brian A. Sparling; Callie Bryan
Trial of tocilizumab in giant-cell arteritis
New England Journal of Medicine, ISSN: 00284793
John H. Stone; Katie Tuckwell; Sophie Dimonaco; Micki Klearman; Aringer; Daniel Blockmans; Elisabeth Brouwer; Maria C. Cid; Bhaskar Dasgupta; Juergen Rech; Carlo Salvarani; Schett; Schulze-Koops; Spiera; Sebastian Unizony; Neil Collinson
Structural insights into lipoprotein N-acylation by Escherichia coli apolipoprotein N-acyltransferase
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Cameron Noland; Michele D. Kattke; Jingyu Diao; Susan Gloor; Homer Pantua; Mike Reichelt; Anand Kumar Katakam; Donghong Yan; Jing Kang; Inna Zilberleyb; Min Xu; Sharookh Kapadia; Jeremy Murray
BMC Bioinformatics, ISSN: 14712105
Jennifer A. Tom; Jens Reeder; Bill Forrest; Robert R. Graham; Julie Hunkapiller; Tim Behrens; Tushar Bhangale