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Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

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Improving the translation of organic anion transporting polypeptide substrates using hek293 cell data in the presence and absence of human plasma via physiologically based pharmacokinetic modelings
Drug Metabolism and Disposition, ISSN: 00909556
Christine M. Bowman; Buyun Chen; Jonathan Cheong; Liling Liu; Yuan Chen; Jialin Mao
Investigating the utility of humanized pregnane X receptor-constitutive androstane receptor-CYP3A4/7 mouse model to assess CYP3A-Mediated Induction
Drug Metabolism and Disposition, ISSN: 00909556
Justin Ly; Susan Wong; Liling Liu; Ruina Li; Kirsten Messick; Jae Chang
PLoS Computational Biology, ISSN: 15537358 1553734X
MacIej Migdal; Dan Fu Ruan; Bill Forrest; Amir Horowitz; Christian Hammer
The Lancet Oncology, ISSN: 14745488 14702045
Peter R. Galle; Richard S. Finn; Shukui Qin; Masafumi Ikeda; Andrew X. Zhu; Tae-You Kim; Masatoshi Kudo; Valeriy Breder; Philippe Merle; Ahmed Kaseb; Daneng Li; Sohail Mulla; Wendy Verret; D-Z Xu; Sairy Hernandez; Beiying Ding; Juan Liu; Chen Huang; Ho Yeong Lim; Ann Lii Cheng; Michel Ducreux
Translational Oncology, ISSN: 19365233
Pankaj Dwivedi
Nature, ISSN: 14764687 00280836
Toni M. Delorey; Carly G. K. Ziegler; Graham Heimberg; Rachelly Normand; Yiming Yang; Asa Segerstolpe; Domenic Abbondanza; Stephen J. Fleming; Ayshwarya Subramanian; Daniel T. Montoro; Karthik A. Jagadeesh; Kushal K. Dey; Pritha Sen; Michal Slyper; Yered H. Pita-Juárez; Devan Phillips; Jana Biermann; Zohar Bloom-Ackermann; Nick Barkas; Andrea Ganna; James Gomez; Johannes C. Melms; Igor Katsyv; Erica Normandin; Pourya Naderi; Yury V. Popov; Siddharth S. Raju; Sebastian Niezen; Linus T.-Y. Tsai; Katherine J. Siddle; Malika Sud; Victoria M. Tran; Shamsudheen K. Vellarikkal; Yiping Wang; Liat Amir-Zilberstein; Deepak S. Atri; Joseph M. Beechem; Olga R. Brook; Jonathan Chen; Prajan Divakar; Phylicia Dorceus; Jesse M. Engreitz; Adam Essene; Donna M. Fitzgerald; Robin Fropf; Steven Gazal; Joshua Gould; John Grzyb; Tyler Harvey; Jonathan Hecht; Tyler Hether; Judit Jané-Valbuena; Michael Leney-Greene; Hui Ma; Cristin McCabe; Daniel E. McLoughlin; Eric M. Miller; Christoph Muus; Mari E. Niemi; Robert Padera; Liuliu P
European Journal of Clinical Pharmacology, ISSN: 14321041 00316970
Benjamin Wu; Stephanie Liu; Marcus Ballinger; Nitzan Sternheim; Hina Patel; Julien Mazieres; Rene A. Bruno
Nature, ISSN: 14764687 00280836
Karen O. Dixon; Marcin Tabaka; Markus A. Schramm; Sheng Xiao; Ruihan Tang; Danielle Dionne; Ana C. Anderson; Orit Rozenblatt-Rosen; Aviv Regev; Vijay K. Kuchroo
TrAC - Trends in Analytical Chemistry, ISSN: 18793142 01659936
Paroma Chakravarty; Karthik Nagapudi
Journal of Pathology, ISSN: 10969896 00223417
Mark Kockx; Mark McCleland; Hartmut Koeppen
New England Journal of Medicine, ISSN: 15334406 00284793
Werth; Joly; Daniel Mimouni; Emanual Maverakis; Caux; Lehane; Gearhart; Audrey Kapre; Pooneh Pordeli; Diana M Chen
BMJ Open, ISSN: 20446055
Sanjoy Ketan Paul; Olga Montvida; Jennie Best; Sara Gale; Attila Pethö-Schramm; Khaled Sarsour
Toxicology and Applied Pharmacology, ISSN: 10960333 0041008X
Rebecca L. Best; Nichole E. LaPointe; Olga Azarenko; Herb Miller; Genualdi; Stephen Chih; Ben-Quan Shen; Mary Ann Jordan; Leslie Wilson; Stuart C. Feinstein; Nicola Stagg
Journal of Clinical Oncology, ISSN: 15277755 0732183X
Moore; Michael A. Bookman; Jalid Sehouli; Austin Miller; Charles Anderson; Giovanni Scambia; Tashanna Myers; Cagatay Taskiran; Katina Robison; Johanna Mäenpää; Lyndsay Willmott; Nicoletta Colombo; Jessica Thomes-Pepin; Michalis Liontos; Michael A. Gold; Yolanda Garcia; Sudarshan K. Sharma; Christopher J. Darus; Carol Aghajanian; Aikou Okamoto; Xiaohua Wu; Rustem Safin; Fan Wu; Luciana Molinero; Maiya; Victor K. Khor; Yvonne G. Lin; Sandro Pignata
eLife, ISSN: 2050084X
Timurs Maculins; Erik Verschueren; Trent Hinkle; Meena Choi; Patrick Chang; Cecile Chalouni; Shilpa Rao; Youngsu Kwon; Junghyun Lim; Anand Kumar Katakam; Ryan C. Kunz; Brian K. Erickson; Ting Huang; Tsung-Heng Tsai; Olga Vitek; Mike Reichelt; Yasin Senbabaoglu; Brent McKenzie; John R. Rohde; Ivan Dikic; Donald S. Kirkpatrick; Aditya Murthy
Journal of Visualized Experiments, ISSN: 1940087X
Dorota Wypych; Daniel Kierecki; Filip M. Golebiowski; Alexis Rohou
Clinical Cancer Research, ISSN: 15573265 10780432
Petrylak; Yohann Loriot; David R. Shaffer; Fadi S. Braiteh; John D. Powderly; Lauren C. Harshman; Paul Conkling; Delord; Michael S. Gordon; Joseph W. Kim; Indrani Sarkar; Kobe Yuen; Edward E. Kadel III; Sanjeev Mariathasan; Carol E. O'Hear; Sujata Narayanan; Marcella Fasso; Susheela Carroll; Thomas Powles
Nature Medicine, ISSN: 1546170X 10788956
Seyedeh M. Zekavat; Shu-Hong Lin; Alexander G. Bick; Aoxing Liu; Kaavya Paruchuri; Chen Wang; Md Mesbah Uddin; Yixuan Ye; Zhaolong Yu; Xiaoxi Liu; Yoichiro Kamatani; Romit Bhattacharya; James P. Pirruccello; Akhil Pampana; Po-Ru Loh; Puja Kohli; Steven A. McCarroll; Krzysztof Kiryluk; Benjamin M. Neale; Iuliana Ionita-Laza; Eric A. Engels; Derek W. Brown; Jordan W. Smoller; Robert C. Green; Elizabeth W. Karlson; Matthew Lebo; Patrick T. Ellinor; Scott T. Weiss; Mark J. Daly; Satoshi Koyama; Kaoru Ito; Yukihide Momozawa; Koichi Matsuda; Yuji Yamanashi; Yoichi Furukawa; Takayuki Morisaki; Yoshinori Murakami; Kaori Muto; Akiko Nagai; Wataru Obara; Ken Yamaji; Kazuhisa Takahashi; Satoshi Asai; Yasuo Takahashi; Takao Suzuki; Nobuaki Sinozaki; Hiroki Yamaguchi; Shiro Minami; Shigeo Murayama; Kozo Yoshimori; Satoshi Nagayama; Daisuke Obata; Masahiko Higashiyama; Akihide Masumoto; Yukihiro Koretsune; Aarno Palotie; Adam Ziemann; Adele Mitchell; Adriana Huertas-Vazquez; Aino Salminen; Airi Jussila; Aki S. Havulinna; A
Clinical Cancer Research, ISSN: 15573265 10780432
Christopher J.M. Williams; Jenny F. Seligmann; Faye Elliott; Michael Shires; Susan D. Richman; Sarah R. Brown; Liping Zhang; Shalini Singh; Judith Pugh; Xiao-Meng Xu; Andrea Muranyi; Christoph Guetter; Auranuch Lorsakul; Uday Kurkure; Zuo Zhao; Jim Martin; Xingwei Wang; Trung Kien Nguyen; Wen-Wei Liu; Dongyao Yan; Nicholas P. West; Jenny Barrett; Michael Barnes; Isaac Bai; Matthew T. Seymour; Philip Quirke; Kandavel Shanmugam
Molecules, ISSN: 14203049
Wei Wang; Cyrus Khojasteh; Dian Su
Comparative Efficacy (DAS28 Remission) of Targeted Immune Modulators for Rheumatoid Arthritis: A Network Meta-Analysis
Rheumatology and Therapy, ISSN: 21986576
Jennie Best; Yuting Kuang; Yilin Jiang; Rajpal Singh; Andreas Karabis; Jennifer Uyei; Joseph Dang; Bill Reiss
Nature Genetics, ISSN: 15461718
Ji Chen; Cassandra N Spracklen; Gaëlle Marenne; Arushi Varshney; Laura J. Corbin; Jian’an Luan; Sara M. Willems; Ying Wu; Xiaoshuai Zhang; Momoko Horikoshi; Thibaud S. Boutin; Reedik Mägi; Johannes Waage; Ruifang Li-Gao; Kei Hang Katie Chan; Jie Yao; Mila D. Anasanti; Audrey Y. Chu; Annique A.J. Claringbould; Jani Heikkinen; Jaeyoung Hong; Jouke-Jan Hottenga; Shaofeng Huo; Marika A. Kaakinen; Tin Louie; Winfried März; Hortensia Moreno-Macías; Anne Ndungu; Sarah C. Nelson; Ilja M Nolte; Kari E. North; Chelsea K. Raulerson; Debashree Ray; Rebecca Rohde; Denis Rybin; Claudia Schurmann; Xueling Sim; Lorraine Southam; Isobel D. Stewart; Carol A Wang; Yujie Wang; Peitao Wu; Weihua Zhang; Tarunveer S. Ahluwalia; Emil V R Appel; Lawrence F Bielak; Jennifer A Brody; Noel Burtt; Claudia P. Cabrera; Brian E. Cade; Jin-Fang Chai; Xiaoran Chai; Li-Ching Chang; Chien-Hsiun Chen; Brian H. Chen; Kumaraswamy Naidu Chitrala; Yen-Feng Chiu; Hugoline G de Haan; Graciela E Delgado; Ayse Demirkan; Qing Duan; Jorgen Engmann;
Diabetologia, ISSN: 14320428 0012186X
Jamie R. J. Inshaw; Carlo Sidore; Francesco Cucca; M. Irina Stefana; Daniel J. M. Crouch; Mark McCarthy; Anubha Mahajan; John A. Todd
Cancer Chemotherapy and Pharmacology, ISSN: 14320843 03445704
Stephanie Liu; Chunze Li
Breast Cancer Research and Treatment, ISSN: 15737217 01676806
Joyce A. O’shaughnessy; Nicholas J. Robert; Srinivas Annavarapu; Jie Zhou; Jesse Sussell; Anna Cheng; Fung Cheng
Calicheamicin antibody-drug conjugates with improved properties
Molecular Cancer Therapeutics, ISSN: 15357163
Breanna S. Vollmar; Chris Frantz; Melissa Schutten; Fiona Zhong; Geoff Del Rosario; MaryAnn Go; Shang-Fan Yu; Douglas Leipold; Amrita Kamath; Carl Ng; Keyang Xu; Josefa Dela Cruz Chuh; Kathy Kozak; Jinhua Chen; Zijin Xu; John Wai; Pragya Adhikari; Hans Erickson; Peter Dragovich; Andy Polson; Thomas Pillow
Inhibition of escherichia coli lipoprotein diacylglyceryl transferase is insensitive to resistance caused by deletion of Braun's lipoprotein
Journal of Bacteriology, ISSN: 00219193
Jingyu Diao; Rie Komura; Tatsuya Sano; Homer Pantua; Kelly Storek; Hiroko Inaba; Haruhiko Ogawa; Cameron Noland; Connie Peng; Susan Gloor; Donghong Yan; Jing Kang; Anand Kumar Katakam; Michael Volny; Peter Liu; Nicholas Nickerson; Wendy Sandoval; Cary Austin; Jeremy Murray; Steven Rutherford; Mike Reichelt; Yiming Xu; Min Xu; Hayato Yanagida; Junichi Nishikawa; Patrick C. Reid; Christian Cunningham; Sharookh Kapadia
Nature, ISSN: 14764687 00280836
Matthew B. Buechler; Rachana Pradhan; Akshay T. Krishnamurty; Christian Cox; Aslihan Karabacak Calviello; Amber W. Wang; Yeqing Angela Yang; Lucinda Tam; Roger Caothien; Meron Roose-Girma; Zora Modrusan; Joe Arron; Richard Bourgon; Sören Müller; Shannon Turley
Simplifying Johanson's roller compaction model to build a “Virtual Roller Compactor” as a predictive tool – Theory and practical application
International Journal of Pharmaceutics, ISSN: 03785173
Chi So; Lap Yin Leung; Ariel Muliadi; Ajit Narang; Chen Mao
Blood, ISSN: 15280020 00064971
Chris Bolen; Federico Mattiello; Michael Herold; Wolfgang Hiddemann; Sarah Huet; Wolfram Klapper; Robert Marcus; Farheen Mir; Gilles Salles; Oliver Weigert; Tina Nielsen; Mikkel Z. Oestergaard; Jeffrey M. Venstrom
Science Translational Medicine, ISSN: 19466242 19466234
Gai Ayalon; Seung-Hye Lee; Oskar Adolfsson; Corinne Foo-Atkins; Jasi Atwal; Mira Blendstrup; Helen Booler; Joseph Bravo; Bob Brendza; Flavia Brunstein; Ruby Chan; Priya Chandra; Jessica Couch; Akash Datwani; Barthelemy Demeule; Danielle DiCara; Rich Erickson; James A. Ernst; Oded Foreman; Dongping He; Isidro Hotzel; Michael Keeley; Michael C M Kwok; Julien Lafrance-Vanasse; Han Lin; Yanmei Lu; Wilman Luk; Paul T. Manser; Andreas Muhs; Hai Ngu; Andrea Pfeifer; Maria Pihlgren; Gautham K. Rao; Kimberly Scearce-Levie; Stephen Schauer; William B. Smith; Hilda Solanoy; Edmond Teng; Kristin Wildsmith; Daniela Bumbaca Yadav; Yong Ying; Reina Fuji; Geoffrey A. Kerchner
Fibroblast-macrophage reciprocal interactions in health, fibrosis, and cancer
Immunity, ISSN: 10747613
Matthew B. Buechler; Wenxian Fu; Shannon Turley
Journal of Organic Chemistry, ISSN: 15206904 00223263
Katherine Townsend; Malcolm Huestis; John C. Tellis
Frontiers in Pharmacology, ISSN: 16639812
Vittal Shivva; Andy Boswell; Hanine Rafidi; Bob Kelley; Amrita Kamath; Susie Crowell
Science immunology, ISSN: 24709468
Christian Cox; Elaine E. Storm; Varun N. Kapoor; Joseph Chavarria-Smith; David L. Lin; Lifen Wang; Yun Li; Noelyn Kljavin; Neko Ota; Travis Bainbridge; Keith Anderson; Meron Roose-Girma; Soren Warming; Joe Arron; Shannon Turley; Frederic De Sauvage; Menno van Lookeren Campagne
Bioinformatics, ISSN: 14602059 13674803
Janina Reeder; Mo Huang; Josh Kaminker; Joe Paulson
Journal of Thoracic Oncology, ISSN: 15561380
Makoto Nishio; Diana Mendus; Lijia Wang; Mark A. Socinski
Nature Cancer, ISSN: 26621347
Alexander H. Pearlman; Michael Hwang; Maximilian F. Konig; Emily Han-Chung Hsiue; Jacqueline Douglass; Sarah R. DiNapoli; Brian J. Mog; Chetan Bettegowda; Drew M. Pardoll; Sandra B. Gabelli; Nicholas Papadopoulos; Kenneth W. Kinzler; Bert Vogelstein; Shibin Zhou
Assessment of low volume sampling technologies: Utility in nonclinical and clinical studies
Bioanalysis, ISSN: 17576180
Kathi Williams; Jeff Lutman; Cynthia McCaughey; Sally Fischer
CPT: Pharmacometrics and Systems Pharmacology, ISSN: 21638306
Gengbo Liu; Dan Lu; James Lu
Gremlin 1+ fibroblastic niche maintains dendritic cell homeostasis in lymphoid tissues
Nature Immunology, ISSN: 15292908
Varun N. Kapoor; Sören Müller; Shilpa Keerthivasan; Markus Brown; Cecile Chalouni; Elaine E. Storm; Alessandra Castiglioni; Ryan Lane; Maximilian Nitschke; Claudia Dominguez; Jillian Astarita; Akshay T. Krishnamurty; Catherine B. Carbone; Yasin Senbabaoglu; Amber W. Wang; Xiumin Wu; Viviana Cremasco; Meron Roose-Girma; Lucinda Tam; Jonas Martin Doerr; Mark Z. Chen; Wyne P. Lee; Zora Modrusan; Yeqing Angela Yang; Richard Bourgon; Wendy Sandoval; Andrey S. Shaw; Frederic De Sauvage; Ira Mellman; Christine Moussion; Shannon Turley
Toxicology and Applied Pharmacology, ISSN: 10960333 0041008X
Kai Connie Wu; Gary Cain; Janice Corpuz; Daqi Xu; Nina Ljumanovic; Ali Zarrin
Clinical Lung Cancer, ISSN: 19380690 15257304
Wong; Ning Wu; Ravi USMA Gupta; Mansfield
International Journal of Pharmaceutical Compounding, ISSN: 10924221
Ada Hui; Jian Yin; Wei Liu; Kai Zheng
Frontiers in Oncology, ISSN: 2234943X
Tony Lima; Danilo Maddalo
Blood, ISSN: 15280020 00064971
Michael U. Callaghan; Claude Negrier; Ido Paz-Priel; Sue Tiffany; Sammy Chebon; Michaela Lehle; Johnny N. Mahlangu; Guy Young; Kruse-Jarres; Mancuso; Markus Niggli; Monet Howard; Nives Selak Bienz; Midori Shima; Jiménez-Yuste; Christophe Schmitt; Elina Asikanius; Gallia Levy; Steven W Pipe; Johannes Oldenburg
Neuron, ISSN: 10974199 08966273
Seung-Hye Lee; Bill Meilandt; Luke Xie; Vineela Gandham; Hai Ngu; Kai Barck; Mitchell G. Rezzonico; Jose Imperio; Guita Lalehzadeh; Melanie Huntley; Kimberly Stark; Oded Foreman; Rick Carano; Brad A. Friedman; Morgan Sheng; Amy Easton; Christopher J. Bohlen; David Hansen
Gaining Efficiency in Clinical Trials With Cardiac Biomarkers: JACC Review Topic of the Week
Journal of the American College of Cardiology, ISSN: 07351097
James L. Januzzi; John M. Canty; Saumya Das; Christopher R. DeFilippi; Gary Gintant; David E. Gutstein; Allan Jaffe; Emily P. Kaushik; Chris Leptak; Cyrus Mehta; Ileana Pina; Thomas J. Povsic; Curtis Rambaran; Rhonda F. Rhyne; Maribel Salas; Victor C. Shi; Jacob A. Udell; Ellis F. Unger; Tanja Zabka; Jonathan H. Seltzer
International Journal of Pharmaceutics, ISSN: 18733476 03785173
Yuchen Fan; Chun-Wan Yen; Hsiu-Chao Lin; Weijia Hou; Alberto Estevez; Apoorva Sarode; Alexandre Goyon; Juan Bian; Jessica Lin; Stefan G. Koenig; Dennis Leung; Karthik Nagapudi; Kelly Zhang
Journal of Pharmaceutical and Biomedical Analysis, ISSN: 1873264X 07317085
Elizabeth S. Hecht; Geoffrey Yeh; Kelly Zhang