Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 101 - 150 OF 10966 RESULTS

ACS Medicinal Chemistry Letters, ISSN: 19485875
Leanna Staben; Shang-Fan Yu; Jinhua Chen; Gang Yan; Zijin Xu; Geoff Del Rosario; Jeffrey Lau; Luna Liu; Jun Guo; Bing Zheng; Josefa Dela Cruz-Chuh; Byoung Chul Lee; Rachana Ohri; Wenwen Cai; Hongxiang Zhou; Kathy Kozak; Keyang Xu; Gail Phillips; Jiawei Lu; John Wai; Andy Polson; Thomas Pillow
New England Journal of Medicine, ISSN: 15334406 00284793
John H. Stone; Micki Klearman; Neil Collinson
Cancer Chemotherapy and Pharmacology, ISSN: 14320843 03445704
Chunze Li; Bei Wang; Shang-Chiung Chen; Russell D. Wada; Dan Lu; Xin Wang; Daniel Polhamus; Jonathan French; Shweta Vadhavkar; Alexander Strasak; Melanie Smitt; Amita Joshi; Meghna Samant; Angelica Quartino; Jin Jin; Sandhya Girish
Protein and Cell, ISSN: 16748018 1674800X
Grace Wang; Mary Mathieu; Randall Brezski
Nature Structural and Molecular Biology, ISSN: 15459985 15459993
Yingnan Zhang; Mark Ultsch; Nicholas Skelton; Dan Burdick; Maureen Beresini; Wei Li Lee; Monica Beltran; Andy Peterson; John Quinn; Cecilia Chiu; Yan Wu; Steven Shia; Paul Moran; Paola Di Lello; Charles Eigenbrot; Daniel Kirchhofer
Molecular Pharmaceutics, ISSN: 15438392 15438384
Dawen Kou; Sudharsan Dwaraknath; Yannick Fischer; Daniel Nguyen; Myeonghui Kim; Hiuwing Yiu; Preeti Patel; Tania Ng; Chen Mao; Matthew Durk; Leslie Chinn; Helen Winter; Larry Wigman; Peter Yehl
Bioanalysis, ISSN: 17576199 17576180
Sally Fischer
Retina, ISSN: 15392864 0275004X
Robert L. Avery; Alessandro A. Castellarin; Nathan C. Steinle; Dilsher S. Dhoot; Dante Joseph Pieramici; Robert See; Stephen Couvillion; MA'An A. Nasir; Melvin D. Rabena; Mauricio Maia; Sherri A. Van Everen; Kha Le; William D. Hanley
Drug Discovery Today, ISSN: 18785832 13596446
Harvey Wong; Tonika Bohnert; Valeriu Damian-Iordache; Christopher Gibson; Cheng-Pang Hsu; Anu Shilpa Krishnatry; Bianca Liederer; Jing Lin; Qiang Lu; Jerome T Mettetal; Daniel R Mudra; Marjoleen JMA Nijsen; Patricia Schroeder; Edgar Schuck; Satyendra Suryawanshi; Patrick Trapa; Alice Tsai; Haiqing Wang; Fan Wu
Advances in Therapy, ISSN: 18658652 0741238X
Gilles Salles; Martin Barrett; Robin Foà; Joerg Maurer; Susan O’Brien; Nancy Valente; Michael Wenger; David G. Maloney
Nature Genetics, ISSN: 15461718 10614036
Diana Chang; Michael A. Nalls; Ingileif B. Hallgrímsdottir; Julie Hunkapiller; Marcel van der Brug; Fang Cai; Geoffrey A. Kerchner; Gai Ayalon; Baris Bingol; Morgan Sheng; David Hinds; Tim Behrens; Andy Singleton; Tushar Bhangale; Robert R. Graham
PLoS ONE, ISSN: 19326203
Mark Merchant; John Moffat; Gabriele Schaefer; Jocelyn Chan; Xiangdan Wang; Christine Orr; Jason Cheng; Thomas Hunsaker; Lily Shao; Stephanie J. Wang; Marie-Claire Wagle; Eva Lin; Pete Haverty; Sheerin Latham; Hai Ngu; Margaret Solon; Jeff Eastham Anderson; Hartmut Koeppen; Shih-Min A. Huang; Jacob Schwarz; Marcia Belvin; Kirouac; Melissa Junttila
EMBO Reports, ISSN: 14693178 1469221X
Mariano Oppikofer; Tianyi Bai; Yutian Gan; Benjamin Haley; Peter Liu; Wendy Sandoval; Claudio Ciferri; Andrea Cochran
European Journal of Immunology, ISSN: 15214141 00142980
Andrea Cossarizza; Hyun-Dong Chang; Andreas Radbruch; Immanuel Andrä; Francesco Annunziato; Petra Bacher; Vincenzo Barnaba; Luca Battistini; Wolfgang M. Bauer; Sabine Baumgart; Burkhard Becher; Wolfgang Beisker; Claudia Berek; Alfonso Blanco; Giovanna Borsellino; Philip E. Boulais; Ryan R. Brinkman; Martin Büscher; Dirk H. Busch; Timothy P. Bushnell; Xuetao Cao; Andrea Cavani; Pratip K. Chattopadhyay; Qingyu Cheng; Sue Chow; Mario Clerici; Anne Cooke; Antonio Cosma; Lorenzo Cosmi; Ana Cumano; Van Duc Dang; Derek Davies; Sara De Biasi; Genny Del Zotto; Silvia Della Bella; Paolo Dellabona; Günnur Deniz; Mark Dessing; Andreas Diefenbach; James P. Di Santo; Francesco Dieli; Andreas Dolf; Vera S. Donnenberg; Thomas Dörner; Götz R. A. Ehrhardt; Elmar Endl; Pablo Engel; Britta Engelhardt; Charlotte Esser; Bart Everts; Christine S. Falk; Todd A. Fehniger; Andrew Filby; Simon Fillatreau; Marie Follo; Irmgard Förster; John Foster; Gemma A. Foulds; Paul S. Frenette; David Galbraith; Natalio Garbi; Maria Dolores Ga
Clinical Immunology, ISSN: 15217035 15216616
Darragh Duffy; Vincent Rouilly; Cecile Braudeau; Véronique Corbière; Raouf Djebali; Marie-Noëlle Ungeheuer; Regis Josien; Samuel T. LaBrie; Olivier Lantz; Delphine Louis; Eva Martinez-Caceres; Francoise Mascart; Jose G. Ruiz de Morales; Catherine Ottone; Lydia Redjah; Nina Salabert-Le Guen; Alain Savenay; Manfred Schmolz; Antoine Toubert; Matthew Albert
CYP1A1-mediated intramolecular rearrangement of aminoazepane in GDC-0339
Drug Metabolism and Disposition, ISSN: 00909556
Ryan Takahashi; Gina Wang; Nathaniel Segraves; Jing Wang; Jae Chang; Cyrus Khojasteh; Shuguang Ma
Pulmonary Pharmacology and Therapeutics, ISSN: 15229629 10945539
Rui Zhu; Yanan Zheng; Nathanael L. Dirks; Shweta Vadhavkar; Jin Yan Jin; Kate Peng; Cecile Holweg; Julie Olsson; John Matthews; Wendy Putnam
Physiological Reviews, ISSN: 15221210 00319333
Chris Siebel; Urban Lendahl
Experimental Biology and Medicine, ISSN: 15353699 15353702
Lorna Ewart; Kristin Fabre; Ananthsrinivas Chakilam; Dragan; David B Duignan; Jeetu Eswaraka; Jinping Gan; Peggy Guzzie-Peck; Monicah A. Otieno; Claire G Jeong; Douglas A. Keller; Sonia M de Morais; Jonathan A. Phillips; Will Proctor; Radhakrishna Sura; Terry Van Vleet; David E. Watson; Yvonne Will; Danilo Tagle; Brian R. Berridge
Haematologica, ISSN: 15928721 03906078
Weihuan Wang; Shuiliang Yu; Jay Myers; Yiwei Wang; William Xin; Marwah Albakri; Alison W. Xin; Ming Li; Alex Y. Huang; Wei Xin; Chris Siebel; Hillard M. Lazarus; Lan Zhou
Ubiquilin1 promotes antigen-receptor mediated proliferation by eliminating mislocalized mitochondrial proteins
eLife,
Alexandra M. Whiteley; Miguel A. Prado; Ivan Peng; Alexander Abbas; Benjamin Haley; Joao A. Paulo; Mike Reichelt; Anand Kumar Katakam; Meredith Sagolla; Zora Modrusan; Dong Yun Lee; Meron Roose-Girma; Don Kirkpatrick; Brent McKenzie; Steven P. Gygi; Daniel Finley; Eric Brown
Xenobiotica, ISSN: 13665928 00498254
Molly Lin; Justin Ly; Ryan Takahashi; John Chen; Alan Deese; Sarah Robinson; Aleksandr Kolesnikov; Susan Wong; Gina Wang; Jae Chang
Preclinical pharmacokinetic characterization of an adipose tissue-targeting monoclonal antibody in obese and non-obese animals
mAbs, ISSN: 19420862
Sharmila Rajan; Danielle Mandikian; Amos Baruch; Tom Gelzleichter; Dale Stevens; Jun Sonoda; Kyra Cowan; Andy Boswell; Eric Stefanich
Photodegradation Pathways of Protein Disulfides: Human Growth Hormone
Pharmaceutical Research, ISSN: 07248741
Daniel Steinmann; Olivier Mozziconacci; Rupesh Bommana; John F. Stobaugh; John Wang; Christian Schöneich
Platform model describing pharmacokinetic properties of vc-MMAE antibody–drug conjugates
Journal of Pharmacokinetics and Pharmacodynamics, ISSN: 1567567X
Kagedal; Leonid Gibiansky; Jian Xu; Xin Wang; Divya Samineni; Shang-Chiung Chen; Dan Lu; Priya Agarwal; Wang; Ola Saad; Neelima Koppada; Bernard Fine; Jin Y. Jin; Sandhya Girish; Chunze Li
Asymmetric Synthesis of Akt Kinase Inhibitor Ipatasertib
Organic Letters, ISSN: 15237060
Chong Han; Scott Savage; Mohammad Al-Sayah; Herbert Yajima; Travis Remarchuk; Reinhard Reents; Beat Wirz; Hans Iding; Stephan Bachmann; Serena M. Fantasia; Michelangelo Scalone; André Hell; Pirmin Hidber; Francis Gosselin
Kumada-Corriu Heteroaryl Cross-Coupling for Synthesis of a Pharmaceutical Intermediate: Comparison of Batch Versus Continuous Reaction Modes
Organic Process Research and Development, ISSN: 10836160
Xin Linghu; Nicholas Wong; Vera Jost; Serena M. Fantasia; Greg Sowell; Francis Gosselin
Pirfenidone reduces respiratory-related hospitalizations in idiopathic pulmonary fibrosis
American Journal of Respiratory and Critical Care Medicine, ISSN: 1073449X
Brett Ley; Jeffrey J. Swigris; Bann-mo Day; John L. Stauffer; Karina Raimundo; Willis Chou; Harold R. Collard
Single-cell dynamics determines response to CDK4/6 inhibition in triple-negative breast cancer
Clinical Cancer Research, ISSN: 10780432
Uzma S. Asghar; Alexis R. Barr; Rosalind J. Cutts; Matthew Beaney; Irina Babina; Deepak Sampath; Jennifer Giltnane; Jennifer Lacap; Lisa Crocker; Amy Young; Alex Pearson; Maria Teresa Herrera-Abreu; Chris Bakal; Nicholas C. Turner
Design of Selective Benzoxazepin PI3Kδ Inhibitors Through Control of Dihedral Angles
ACS Medicinal Chemistry Letters,
Brian Safina; Richard Elliott; Andrew K. Forrest; Robert Heald; Jeremy Murray; Jim Nonomiya; Jodie Pang; Laurent Salphati; Eileen M. Seward; Steven Staben; Mark Ultsch; Binqing Wei; Wenqian Yang; Dan Sutherlin
Protein engineering to increase the potential of a therapeutic antibody Fab for long-acting delivery to the eye
mAbs, ISSN: 19420862
Devin Tesar; Jacob Luoma; Emily A. Wyatt; Catherine Shi; Whitney Shatz; Phil Hass; Mary Mathieu; Li Yi; Jacob E. Corn; Katie F. Maass; Kathryn Wang; Michelle Z. Dion; Nisana Andersen; Kelly Loyet; Menno van Lookeren Campagne; Karthik Rajagopal; Leslie Dickmann; Justin Scheer; Robert F. Kelley
Randomized phase III trial of trastuzumab plus capecitabine with or without pertuzumab in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer who experienced disease progression during or after trastuzumab-based therapy
Journal of Clinical Oncology, ISSN: 0732183X
Ander Urruticoechea; Mohammed Rizwanullah; Seock-Ah Im; Antonio Carlos Sánchez Ruiz; István Láng; Gianluca Tomasello; Hannah Douthwaite; Tanja Badovinac Crnjevic; Sarah Heeson; Jennifer Eng-Wong; Montserrat Muñoz
Journal of the American Chemical Society, ISSN: 15205126 00027863
Kyle A. Mack; Andrew McClory; Haiming Zhang; Francis Gosselin; David B. Collum
Autophagy, ISSN: 15548635 15548627
Marianne R. Spalinger; Silvia Lang; Claudia Gottier; Xuezhi Dai; David J. Rawlings; Andrew C. Chan; Gerhard Rogler; Michael Scharl
Lung Cancer, ISSN: 18728332 01695002
Lukas Bubendorf; Urania Dafni; Martin Schöbel; Stephen P. Finn; Verena Tischler; Aleksandra Sejda; Antonio Marchetti; Erik Thunnissen; Eric K. Verbeken; Arne Warth; Irene Sansano; Richard Cheney; Ernst Jan M. Speel; Daisuke Nonaka; Kim Monkhorst; Henrik Hager; Miguel Martorell; Spasenija Savic; Keith M. Kerr; Qiang Tan; Zoi Tsourti; Thomas R. Geiger; Roswitha Kammler; Katja Schulze; Ashis Das-Gupta; David Shames; Solange Peters; Rolf A Stahel
RMD Open, ISSN: 20565933
Strand; Margaret Michalska; Christine Birchwood; Jinglan Pei; Katie Tuckwell; Rebecca Finch; Cem Gabay; Arthur Kavanaugh; Graeme Jones
Protein Engineering, Design and Selection, ISSN: 17410134 17410126
Mark Ultsch; Andrew Charles Braisted; Henry Maun; Charles Eigenbrot
Respiration, ISSN: 14230356 00257931
Ulrich Costabel; Carlo Albera; Lisa H Lancaster; Chin-Yu Lin; Philip Hormel; Henry N. Hulter; Paul W Noble
Protein Engineering, Design and Selection, ISSN: 17410134 17410126
Hok Seon Kim; Diana Ronai Dunshee; Angie Yee; Raymond Tong; Ingrid Kim; Farzam Farahi; Jo-Anne Hongo; James Ernst; Jun Sonoda; Christoph Spiess
A phase ib dose-escalation study of the safety, tolerability, and pharmacokinetics of cobimetinib and duligotuzumab in patients with previously treated locally advanced ormetastatic cancers with mutant KRAS
Oncologist, ISSN: 10837159
Christopher H. Lieu; Manuel Hidalgo; Jordan Berlin; Andrew H. Ko; Andrés Cervantes; Patricia M. LoRusso; David E. Gerber; Paul Eder; Gail Eckhardt; Amy Kapp; Amy Tsuhako; Bruce McCall; Andrea Pirzkall; Anne Uyei; Tabernero
Cotargeting of MEK and PDGFR/STAT3 pathways to treat pancreatic ductal adenocarcinoma
Molecular Cancer Therapeutics, ISSN: 15357163
Nisebita Sahu; Emily Chan; Felix Chu; Thinh Pham; Hartmut Koeppen; Bill Forrest; Mark Merchant; Jeffrey Settleman
Gene expression profiling in BRAF-mutated melanoma reveals patient subgroups with poor outcomes to vemurafenib that may be overcome by cobimetinib plus vemurafenib
Clinical Cancer Research, ISSN: 10780432
Matthew Wongchenko; Grant A. McArthur; Brigitte Dréno; James Larkin; Paolo A. Ascierto; Jeffrey A. Sosman; Luc Andries; Mark Kockx; Stephen D. Hurst; Ivor Caro; Isabelle Rooney; Priti Hegde; Luciana Molinero; Huibin Yue; Ilsung Chang; Lukas Amler; Yibing Yan; Antoni Ribas
Veterinary Pathology, ISSN: 15442217 03009858
Cindy A. Farman; Chris Schuetz; Florence Lorget; Vladimir Bantseev; David Calise; Evan Thackaberry
Vision-related functional burden of diabetic retinopathy across severity levels in the United States
JAMA Ophthalmology, ISSN: 21686165
Jeffrey R. Willis; Quan V. Doan; Michelle Gleeson; Zdenka Haskova; Pradeep Ramulu; Lawrence S. Morse; Ronald Cantrell
Advances in Therapy, ISSN: 18658652 0741238X
Lin Pan; Paula Belloni; Han Ting Ding; Jianshuang Wang; Christopher M. Rubino; Wendy Putnam
Nature Genetics, ISSN: 15461718 10614036
Rebecca Sims; Sven J. Van Der Lee; Adam C. Naj; Celine Bellenguez; Nandini Badarinarayan; Johanna Jakobsdottir; Brian W. Kunkle; Anne Boland; Rachel Raybould; Joshua C. Bis; Eden R. Martin; Benjamin Grenier-Boley; Stefanie Heilmann-Heimbach; Vincent Chouraki; Amanda B. Kuzma; Kristel Sleegers; Maria Vronskaya; Agustin Ruiz; Robert R. Graham; Robert Olaso; Per Hoffmann; Megan L. Grove; Badri N. Vardarajan; Mikko Hiltunen; Markus M. Nöthen; Charles C. White; Kara L. Hamilton-Nelson; Jacques Epelbaum; Wolfgang Maier; Seung-Hoan Choi; Gary W. Beecham; Cécile Dulary; Stefan Herms; Albert V. Smith; Cory C. Funk; Céline Derbois; Andreas J. Forstner; Shahzad Ahmad; Hongdong Li; Delphine Bacq; Denise Harold; Claudia L. Satizabal; Otto Valladares; Alessio Squassina; Rhodri Thomas; Jennifer Brody; Liming Qu; Pascual Sánchez-Juan; Taniesha Morgan; Frank J Wolters; Yi Zhao; Florentino Sanchez Garcia; Nicola Denning; Myriam Fornage; John Malamon; Maria Candida Deniz Naranjo; Elisa Majounie; Thomas H Mosley; Beth A. Dom
New England Journal of Medicine, ISSN: 15334406 00284793
Johannes Oldenburg; Johnny N. Mahlangu; Benjamin Kim; Christophe Schmitt; Michael U. Callaghan; Guy Young; Elena Santagostino; Rebecca Krusejarres; Claude Negrier; Craig Kessler; Nancy Valente; Elina Asikanius; Gallia G. Levy; Jerzy Windyga; Midori Shima
Nature, ISSN: 14764687 00280836
Mohamed Lamkanfi; Vishva Dixit
AAPS Journal, ISSN: 15507416
Andre Hermans; Andreas M. Abend; Filippos Kesisoglou; Talia Flanagan; Michael J. Cohen; Dorys A. Diaz; Mao; Limin Zhang; Gregory K. Webster; Yiqing Lin; David Hahn; Carrie A. Coutant; Haiyan Grady
Journal of Clinical Oncology, ISSN: 15277755 0732183X
Solange Peters; Scott Gettinger; Melissa L. Johnson; Pasi A. Jänne; Marina C. Garassino; Daniel Christoph; Chee Keong Toh; Naiyer A. Rizvi; Jamie E. Chaft; Enric Carcereny Costa; Jyoti D. Patel; Laura Q.M. Chow; Marianna Koczywas; Cheryl Ho; Martin Früh; Michel Van Den Heuvel; Jeffrey Rothenstein; Martin Reck; Luis Paz-Ares; Frances A. Shepherd; Takayasu Kurata; Zhengrong Li; Jiaheng Qiu; Marcin Kowanetz; Simonetta Mocci; Geetha Shankar; Alan Sandler; Enriqueta Felip