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Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

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Journal of Clinical Oncology, ISSN: 15277755
Stephen V. Liu; Martin Reck; Mansfield; Tony Mok; Arnaud Scherpereel; Niels Reinmuth; Marina C. Garassino; Javier De Castro Carpeno; Califano; Makoto Nishio; Orlandi; Jorge Alatorre-Alexander; Leal; Ying Cheng; Jong-Seok Lee; Lam; Mark McCleland; Deng; See Phan; Leora Horn
Journal of Pharmaceutical and Biomedical Analysis, ISSN: 1873264X 07317085
Steven Chin; Tao Chen; Rami Hannoush; Christopher M. Crittenden
Science, ISSN: 10959203 00368075
Ramesh A. Shivdasani; Hans Clevers; Frederic De Sauvage
Organic Process Research and Development, ISSN: 1520586X 10836160
Sayyeda Zeenat A. Razvi; Isabelle Kamm; Tina Nguyen; Jackson Pellett; Archana Kumar
Clinical Cancer Research, ISSN: 15573265 10780432
Anneleen Daemen; Jonathan E. Cooper; Szymon Myrta; Matthew Wongchenko; Eva Lin; Jason E. Long; Oded Foreman; Zora Modrusan; Jarrod Tremayne; Cecile de la Cruz; Mark Merchant; Scott E. Martin; Yibing Yan; Melissa Junttila
Exploring Human Skin Aging at the Single-Cell Level
Developmental Cell, ISSN: 15345807
Mary Mohrin; Heinrich Jasper
Analyst, ISSN: 13645528 00032654
Julien Camperi; Alexandre Goyon; Davy Guillarme; Kelly Zhang; Cinzia Stella
A phase 2 study of venetoclax plus R-CHOP as first-line treatment for patients with diffuse large B-cell lymphoma
Blood, ISSN: 00064971
Morschhauser; Pierre Feugier; Ian Flinn; Robin Gasiorowski; Greil; Illés; Nathalie A. Johnson; Jean-François Larouche; Pieternella J. Lugtenburg; Caterina Patti; Gilles Salles; Marek Trněný; Sven De Vos; Farheen Mir; Divya Samineni; Su Young Kim; Yanwen Jiang; Elizabeth Punnoose; Arijit Sinha; Emma Clark; Nathalie Spielewoy; Kathryn Humphrey; Alexandra Bazeos; Zelenetz
2020 White Paper on Recent Issues in Bioanalysis: BMV of Hybrid Assays, Acoustic MS, HRMS, Data Integrity, Endogenous Compounds, Microsampling and Microbiome (<underline>Part 1</underline> - Recommendations on Industry/Regulators Consensus on BMV of Biotherapeutics by LCMS, Advanced Application in Hybrid Assays, Regulatory Challenges in Mass Spec, Innovation in Small Molecules, Peptides and Oligos)
Bioanalysis, ISSN: 17576180
Hendrik Neubert; Stephen C. Alley; Anita Lee; Wenying Jian; Michael H. Buonarati; Anna Edmison; Fabio Garofolo; Boris Gorovits; Sam Haidar; Bill Mylott; Parya Nouri; Mark Qian; Stephen Vinter; Voelker; Jan Welink; Jiang Wu; Eric Yang; Hongbin Yu; Christopher Evans; Scott Summerfield; Jian Wang; Kevin Bateman; Jason Boer; Brian Dean; Lieve Dillen; Patrick Faustino; Luca Ferrari; Nicola Hughes; Lina Luo; Timothy Olah; Noah Post; Spellman; Jens Sydor; Hui Zhang; Jenny Zhang; Jinhui Zhang; Christine Fandozzi; Amanda Wilson; Daniela Fraier; Chris Beaver; Suman Dandamudi; Arindam Dasgupta; Rebecca Elliott; Allena Ji; Wenkui Li; Michael McGuinness; Gustavo Mendes Lima Santos; Tahseen Mirza; Natasha Savoie; Diaa Shakleya; Sune Sporring; Susan Stojdl; Phillip Sundman; Nilufer Tampal; Eric Woolf
An anti–CD22-seco-CBI-dimer antibody–drug conjugate (ADC) for the treatment of non-hodgkin lymphoma that provides a longer duration of response than auristatin-based ADCs in preclinical models
Molecular Cancer Therapeutics, ISSN: 15357163
Shang-Fan Yu; Donna Lee; Bing Zheng; Geoff Del Rosario; Douglas Leipold; Helen Booler; Fiona Zhong; Montse Carrasco-Triguero; Kyu Hong; Peter Yan; Rebecca K. Rowntree; Melissa Schutten; Thomas Pillow; Jack D. Sadowsky; Peter Dragovich; Andy Polson
An expanded analysis framework for multivariate GWAS connects inflammatory biomarkers to functional variants and disease
European Journal of Human Genetics, ISSN: 10184813
Sanni E. Ruotsalainen; Juulia J. Partanen; Anna Cichonska; Jake Lin; Christian Benner; Ida Surakka; Aarno Palotie; Mark Daly; Howard Jacob; Heiko Runz; Sally John; Robert M. Plenge; Mark I. McCarthy; Dawn Waterworth; Caroline Fox; Anders Mälarstig; Kathy Klinger; Kathy Call; Tomi Mäkelä; Jaakko Kaprio; Petri Virolainen; Kari Pulkki; Terhi Kilpi; Markus Perola; Jukka Partanen; Anne Pitkäranta; Riitta Kaarteenaho; Seppo Vainio; Veli-Matti Kosma; Urho Kujala; Jeff Waring; Heiko Runz; Jimmy Liu; Shameek Biswas; Dawn Waterworth; Meg Ehm; Caroline S. Fox; Anders Malarstig; Catherine Marshall; Xinli Hu; Kathy Call; Kathy Klinger; Matthias Gossel; Samuli Ripatti; Johanna Schleutker; Markus Perola; Mikko Arvas; Olli Carpen; Reetta Hinttala; Johannes Kettunen; Reijo Laaksonen; Arto Mannermaa; Juha Paloneva; Urho Kujala; Outi Tuovila; Minna Hendolin; Raimo Pakkanen; Hilkka Soininen; Valtteri Julkunen; Anne Remes; Reetta Kälviäinen; Mikko Hiltunen; Jukka Peltola; Pentti Tienari; Juha Rinne; Adam Ziemann; Jeffrey Wa
Characterization of robust immune responses to a bispecific antibody, a novel class of antibody therapeutics
Bioanalysis, ISSN: 17576180
Kate Peng; Ketevan Siradze; Sally Fischer
Gut CD4+ T cell phenotypes are a continuum molded by microbes, not by TH archetypes
Nature Immunology, ISSN: 15292908
Elijah Willie; Hugo Schmutz; Jodie Chandler; Alexandra Schnell; Pratiksha I. Thakore; Graham LeGros; Sara Mostafavi; Mathis; Christophe Benoist; Oscar Aguilar; Rhys Allan; Jillian Astarita; K Frank Austen; Nora A. Barrett; Alev Baysoy; Christophe Benoist; Brian D. Brown; Matthew B. Buechler; Jason D. Buenrostro; Maria Acebes Casanova; Kyunghee Choi; Kaitavjeet Chowdhary; Marco Colonna; Ty Crowl; Tianda Deng; Jigar V. Desai; Fiona Desland; Maxime Dhainaut; Jiarui Ding; Claudia Dominguez; Daniel F. Dwyer; Michela Frascoli; Shani Gal-Oz; Ananda Goldrath; Ricardo Grieshaber-Bouyer; Baosen Jia; Tim Johanson; Stefan Jordan; Joonsoo Kang; Varun N. Kapoor; Ephriam Kenigsberg; Joel Kim; Ki wook Kim; Evgeny Kiner; Mitchell Kronenberg; Lewis Lanier; Catherine Laplace; Caleb A. Lareau; Andrew Leader; Jisu Lee; Assaf Magen; Barbara Maier; Alexandra Maslova; Diane Mathis; Adelle McFarland; Miriam Merad; Etienne Meunier; Monach; Sara Mostafavi; Sören Müller; Christoph Muus; Hadas Ner-Gaon; Quyhn Nguyen; Peter A. Nigrovi
Improving cryo-EM structure validation
Nature Methods,
Alexis Rohou
NRF2 Activation promotes aggressive lung cancer and associates with poor clinical outcomes
Clinical Cancer Research, ISSN: 10780432
Anju Singh; Anneleen Daemen; Dorothee Nickles; Sang-Min Jeon; Oded Foreman; Kuladeep Sudini; Florian Gnad; Stephane Lajoie; Naina Gour; Wayne Mitzner; Samit Chatterjee; Eun-Ji Choi; Buvana Ravishankar; Amy Rappaport; Namrata S. Patil; Mark McCleland; Leisa Johnson; George Acquaah-Mensah; Edward Gabrielson; Shyam Biswal; Georgia Hatzivassiliou
Phase 2 trial to assess lebrikizumab in patients with idiopathic pulmonary fibrosis
European Respiratory Journal, ISSN: 09031936
Toby M. Maher; Ulrich Costabel; Marilyn K Glassberg; Yasuhiro Kondoh; Takashi Ogura; Mary Beth Scholand; David Kardatzke; Monet Howard; Julie Olsson; Margaret Neighbors; Paula Belloni; Jeffrey J. Swigris
Ophthalmic Surgery Lasers and Imaging Retina, ISSN: 23258179 23258160
Roger A. Goldberg; Lauren Hill; Tatiana Davis; Carlos Quezada Ruiz
Nature Medicine, ISSN: 1546170X 10788956
Livnat Jerby-Arnon; Cyril Neftel; Marni E. Shore; Hannah R. Weisman; Nathan D. Mathewson; Matthew J. McBride; Brian Haas; Benjamin Izar; Angela Volorio; Gaylor Boulay; Luisa Cironi; Alyssa R. Richman; Liliane C. Broye; Joseph M. Gurski; Christina C. Luo; Ravindra Mylvaganam; Lan Nguyen; Shaolin Mei; Johannes C. Melms; Christophe Georgescu; Ofir Cohen; Jorge E. Buendia-Buendia; Asa Segerstolpe; Malika Sud; Michael S. Cuoco; Danny Labes; Simon Gritsch; Daniel R. Zollinger; Nicole Ortogero; Joseph M. Beechem; Petur Nielsen; Ivan Chebib; Tu Nguyen-Ngoc; Michael Montemurro; Gregory M. Cote; Edwin Choy; Igor Letovanec; Stéphane Cherix; Nikhil Wagle; Peter K. Sorger; Alex B. Haynes; John T. Mullen; Ivan Stamenkovic; Miguel N. Rivera; Cigall Kadoch; Kai W. Wucherpfennig; Orit Rozenblatt-Rosen; Mario L. Suvà; Nicolò Riggi; Aviv Regev
American Journal of Physiology - Cell Physiology, ISSN: 15221563 03636143
Elsa-Noah N’Diaye; Ryan Cook; Hua Wang; Ping Wu; Ryan LaCanna; Cong Wu; Zhengmao Ye; Dhaya Seshasayee; Meredith Hazen; WeiYu Lin; Tulika Tyagi; Isidro Hotzel; Lucinda Tam; Robert J (Research) Newman; Meron Roose-Girma; Paul J. Wolters; Ning Ding
Journal of Clinical Oncology, ISSN: 15277755
Scott Kopetz; Katherine A. Guthrie; Van Morris; Heinz-Josef Lenz; Anthony Magliocco; Dipen Maru; Yibing Yan; Richard Lanman; Ganiraju Manyam; David Hong; Alexey V. Sorokin; Chloe E. Atreya; Luis A. Diaz; Carmen Allegra; Kanwal P. Raghav; Stephen E. Wang; Christopher H. Lieu; Shannon L. McDonough; Philip A. Philip; Hochster
Nature Cancer, ISSN: 26621347
Jianzhu Ma; Samson H. Fong; Yunan Luo; Christopher J. Bakkenist; John Paul Shen; Soufiane Mourragui; Lodewyk F. A. Wessels; Marc Hafner; Roded Sharan; Jian Peng; Trey Ideker
JAMA Ophthalmology, ISSN: 21686173 21686165
Michael Javaheri; Lauren Hill; Avanti Ghanekar; Ivo Stoilov
Journal of Prevention of Alzheimer&#39;s Disease, ISSN: 24260266 22745807
Fiona McDougall; Edgar; Mertes; Paul Delmar; Fontoura; Danielle Abi-Saab; Lansdall; Mercè Boada; Rachelle Doody
European Journal of Organic Chemistry, ISSN: 10990690 1434193X
Malcolm Huestis; Jean-Philippe Leclerc; Larouche-Gauthier; Samuel Aubert-Nicol; Arun Yadav; Koilpitchai Sivamuthuraman
Phase I basket study of taselisib, an isoform-selective PI3K inhibitor, in patients with PIK3CA-mutant cancers
Clinical Cancer Research, ISSN: 10780432
Komal Jhaveri; Matthew T. Chang; Dejan Juric; Saura; Valentina Gambardella; Anton Melnyk; Manish R. Patel; Vincent Ribrag; Cynthia X. Ma; Raid Aljumaily; Philippe L. Bedard; Jasgit C. Sachdev; Lara Dunn; Helen Won; John Bond; Surai Jones; Heidi Savage; Maurizio Scaltriti; Tim Wilson; Michael C. Wei; David M. Hyman
New England Journal of Medicine, ISSN: 15334406 00284793
Carlos Salama; Jian Han; Linda Yau; Bill Reiss; Benjamin Kramer; Jeffrey D. Neidhart; Gerard J. Criner; Emma Kaplan-Lewis; Rachel Baden; Lavannya Pandit; Miriam L. Cameron; Julia Garcia-Diaz; Victoria Chávez; Martha Mekebeb-Reuter; Ferdinando Lima De Menezes; Reena Shah; Maria F. González-Lara; Beverly Assman; Jamie Freedman; Shalini V. Mohan
An Approach to Bioactivity Assessment for Critical Quality Attribute Identification Based on Antibody-Antigen Complex Structure
Journal of Pharmaceutical Sciences, ISSN: 00223549
Xuan Gao; Weiru Wang; Devin Tesar; Bingchuan Wei; John Eschelbach; Robert F. Kelley; Guoying Jiang
Cell death pathways: intricate connections and disease implications
EMBO Journal, ISSN: 02614189
Matthias Kist; Domagoj Vucic
Annals of Oncology, ISSN: 15698041 09237534
Helen Gogas; Dréno; James Larkin; Lev Demidov; Daniil Stroyakovskiy; Eroglu; Francesco Ferrucci; Pigozzo; Rutkowski; Mackiewicz; Isabelle Rooney; Athina Voulgari; Troutman; Bethany Pitcher; Guo; Yibing Yan; Marcela Castro; Sohail Mulla; Keith Flaherty; Arance
The Lancet Respiratory Medicine, ISSN: 22132619 22132600
Liam G. Heaney; John Busby; Catherine E. Hanratty; Ratko Djukanovic; Ashley Woodcock; Samantha M Walker; Tim Hardman; Joe Arron; David Choy; Peter Bradding; Chris E. Brightling; Rekha Chaudhuri; Douglas Cowan; Adel Mansur; Stephen J. Fowler; Robert Niven; Peter H. Howarth; James Lordan; Andrew Menzies-Gow; Tim W Harrison; Douglas S Robinson; Cecile Holweg; John Matthews; Ian D. Pavord; Ian Adcock; Adnam Azim; Mary Bellamy; Catherine Borg; Michelle Bourne; Clare Connolly; Richard W. Costello; Chris Corrigan; Sarah Davies; Gareth Davies; Kian Fan Chung; Gainsborough; Traceyanne Grandison; Beverley Hargadon; Horn; Val Hudson; David Jackson; Sebastian Johnston; Geraldine Jones; Paula McCourt; Maria Nunez; Dominic E Shaw; Katherine Smith; Joel Solis; Roisin Stone; Freda Yang
Journal of Immunological Methods, ISSN: 18727905 00221759
Kathryn E. Yoh; Christopher J. Lowe; Shilpi Mahajan; Becky Suttmann; Trung Nguy; Mike Reichelt; Jenny Yang; Rachel Melendez; Yijin Li; Luciana Molinero; Jane Ruppel; Wenfeng Xu; Vicki Plaks
Journal of the American Chemical Society, ISSN: 15205126 00027863
Tyler J. Fulton; Alexander Q. Cusumano; Eric J. Alexy; Yun E. Du; Haiming Zhang; Houk; Brian M. Stoltz
Nature Immunology, ISSN: 15292916 15292908
Meidi Gu; Xiaofei Zhou; Jee Hyung Sohn; Lele Zhu; Zuliang Jie; Jin-Young Yang; Xiaofeng Zheng; Xiaoping Xie; Jie Yang; Yaoyao Shi; Hans Brightbill; Jae Bum Kim; Jing Wang; Xuhong Cheng; Shao-Cong Sun
NINJ1 mediates plasma membrane rupture during lytic cell death
Nature, ISSN: 00280836
Nobuhiko Kayagaki; Opher S. Kornfeld; Bettina L. Lee; Irma Stowe; Karen O’Rourke; Qingling Li; Wendy Sandoval; Donghong Yan; Jing Kang; Min Xu; Juan Zhang; Wyne P. Lee; Brent McKenzie; Gözde Ulas; Jian Payandeh; Meron Roose-Girma; Zora Modrusan; Rohit Reja; Meredith Sagolla; Joshua D. Webster; Vicky Cho; T. Daniel Andrews; Lucy X. Morris; Lisa A. Miosge; Christopher C. Goodnow; Edward M. Bertram; Vishva Dixit
mAbs, ISSN: 19420870 19420862
Josefa Dela Cruz Chuh; MaryAnn Go; Yvonne Chen; Jun Guo; Hanine Rafidi; Danielle Mandikian; Yonglian Sun; Zhonghua Lin; Kellen Schneider; Pamela Zhang; Rajesh Vij; Danielle Sharpnack; Pamela Chan; Cecile de la Cruz; Jack D. Sadowsky; Dhaya Seshasayee; JT Koerber; Thomas Pillow; Gail D. Phillips; Rebecca K. Rowntree; Andy Boswell; Kathy Kozak; Andy Polson; Paul Polakis; Shang-Fan Yu; Peter Dragovich; Nick Agard
Ubiquitination in the regulation of inflammatory cell death and cancer
Cell Death and Differentiation, ISSN: 13509047
Peter E. Cockram; Matthias Kist; Sumit Prakash; Si-Han Chen; Ingrid Wertz; Domagoj Vucic
American Journal of Respiratory and Critical Care Medicine, ISSN: 15354970 1073449X
Johan Kolmert; Cristina Gomez; David Balgoma; Marcus Sjödin; Johan Bood; Jon Konradsen; Magnus Ericsson; John-Olof Thörngren; James; Maria Mikus; Ana R. Sousa; John Riley; Stewart Bates; Per Bakke; Ioannis Pandis; Massimo Caruso; Pascal Chanez; Stephen J. Fowler; Thomas Geiser; Peter H. Howarth; Ildikó Horváth; Norbert Krug; Paolo Montuschi; Marek Sanak; Annelie F. Behndig; Dominick E. Shaw; Richard G. Knowles; Cecile Holweg; Asa M. Wheelock; Barbro Dahlén; Björn Nordlund; Alving; Gunilla Hedlin; Kian Fan Chung; Ian Adcock; Peter J. Sterk; Ratko Djukanovic; Sven-Erik Dahlen; Craig E. Wheelock
Journal of Allergy and Clinical Immunology, ISSN: 10976825 00916749
Philippe Gevaert; Jonathan Corren; Joaquim Mullol; Joseph Han; Stella E. Lee; Monica Ligueros-Saylan; Kit Wong; Ted Omachi; Claus Bachert
Xenobiotica, ISSN: 13665928 00498254
Qin Yue; S. Cyrus Khojasteh; Sungjoon Cho; Shuguang Ma; Teresa Mulder; John Chen; Jodie Pang; Xiao Ding; Alan Deese; Jackson D. Pellet; Nicholas Siebers; Lori Joas; Laurent Salphati; Joseph A. Ware
Annals of Oncology, ISSN: 15698041 09237534
Eleftherios P. Mamounas; Untch; Max Mano; Chiun-Sheng Huang; Charles E. Geyer Jr.; von Minckwitz; Wolmark; Pivot; Sherko Kuemmel; Michael P. DiGiovanna; Kaufman; Georg Kunz; Alison K. Conlin; Juan Carlos Alcedo; Kuehn; Irene L. Wapnir; Fontana; Hackmann; Jonathan Polikoff; Saghatchian; Adam Brufsky; Yang; Zimovjanova; Thomas Boulet; Haiying Liu; David Tesarowski; Lisa H. Lam; Chunyan Song; Melanie Smitt; Sibylle Loibl
Journal of Allergy and Clinical Immunology, ISSN: 10976825 00916749
Steven G. Kelsen; Ioana Agache; Weily Soong; Elliot Israel; Geoffrey L. Chupp; Dorothy S. Cheung; Wiebke Theess; Xiaoying Yang; Tracy Staton; David Choy; Alice Fong; Ajit Dash; Michael J. Dolton; Rajita Pappu; Chris E. Brightling
European Urology, ISSN: 18737560 03022838
Michiel S Van Der Heijden; Yohann Loriot; Ignacio Durán; Alain Ravaud; Margitta M. Retz; Nicholas J. Vogelzang; Betty Nelson; Jingjing Wang; Xiaodong Shen; Thomas Powles
JCO Clinical Cancer Informatics, ISSN: 24734276
Carsten Schröder; Marcus Lawrance; Chen Li; Christelle Lenain; Shivani K. Mhatre; Marwan Fakih; Irmarie Reyes-Rivera; Michael T. Bretscher
Journal of Diabetes Science and Technology, ISSN: 19322968
Sonoko Kawakatsu; Xiaohan Liu; Brandon Tran; Brittany P. Tran; Lucy Manzanero; Eric Shih; Allen Shek; Jeremy Lim
Organic Process Research and Development, ISSN: 1520586X 10836160
Charlotte Dalton; Louis Diorazio; Jaika Doerfler; Oliver D. Engl; Zhengxu S. Han; Gareth Howell; Jonathan Latham; Wei Li; Mark McLaws; Rachel Munday; Antonio Navarro; Michael Parmentier; Jan Pawlas; Paul Richardson; Gheorghe-Doru Roiban; Alan Steven; Jack Terrett; Daniel S. Treitler; Mingshuo Zeng
Population pharmacokinetic and exploratory exposure–response analysis of the fixed-dose combination of pertuzumab and trastuzumab for subcutaneous injection in patients with HER2-positive early breast cancer in the FeDeriCa study
Cancer Chemotherapy and Pharmacology, ISSN: 03445704
Wang; Rong Deng; Stefanie Hennig; Tanja Badovinac-Crnjevic; Monika Kaewphluk; Kagedal; Angelica Quartino; Sandhya Girish; Chunze Li; Whitney P. Kirschbrown
ACS Medicinal Chemistry Letters, ISSN: 19485875
Malcolm Huestis; Matthew Durk; Charles Eigenbrot; Paul Gibbons; Thomas Hunsaker; Hank La; Dennis H. Leung; Wendy Liu; Shiva Malek; Mark Merchant; John Moffat; Christine S. Muli; Christine Orr; Brendan T. Parr; Frances Shanahan; Christopher Sneeringer; Weiru Wang; Ivana Yen; Peter Yin; Joachim Rudolph; Mike Siu
Cancer Chemotherapy and Pharmacology, ISSN: 14320843 03445704
Mathilde Marchand; Rong Zhang; Phyllis Chan; Valerie Quarmby; Marcus Ballinger; Nitzan Sternheim; Benjamin Wu; Jin Yan Jin; Rene A. Bruno
Translational and pharmacokinetic-pharmacodynamic application for the clinical development of GDC-0334, a novel TRPA1 inhibitor
Clinical and Translational Science, ISSN: 17528054
Phyllis Chan; Han Ting Ding; Bianca Liederer; Jialin Mao; Paula Belloni; Liuxi Chen; Simon S. Gao; Victory Joseph; Xiaoying Yang; Joseph S. Lin; Mayur S. Mitra; Wendy Putnam; Angelica Quartino; Rebecca N. Bauer; Lin Pan
Treatment patterns in US patients hospitalized with COVID-19 and pulmonary involvement
Journal of Medical Virology, ISSN: 01466615
Jennie Best; Amanda M. Kong; Emma Kaplan-Lewis; Otis W. Brawley; Rachel Baden; James Zazzali; Karen S. Miller; James Loveless; Krutika Jariwala-Parikh; Shalini V. Mohan