Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 1 - 50 OF 11736 RESULTS

IL-17A is associated with the breakdown of the blood-brain barrier in relapsing-remitting multiple sclerosis
Journal of Neuroimmunology, ISSN: 01655728
Francesca Setiadi; Alexander Abbas; Surinder Jeet; Kit Wong; Antje Bischof; Ivan Peng; James Lee; Meire Bremer; Erica L. Eggers; Jason DeVoss; Tracy Staton; Ann Herman; H. -Christian von Büdingen; Michael Townsend
The Lancet Oncology, ISSN: 14745488 14702045
Howard West; Michael McCleod; Maen Hussein; Alessandro Morabito; Achim Rittmeyer; Henry J Conter; Hans-Georg Kopp; Davey B Daniel; Steven McCune; Tarek Mekhail; Alona Zer; Niels Reinmuth; Ahad Sadiq; Alan Sandler; Wei Lin; Tania Ochi Lohmann; Venice Archer; Lijia Wang; Marcin Kowanetz; Federico Cappuzzo
Effects of PI3K Inhibition on Afucosylated Antibody-Driven FcγRIIIa Events and Phospho-S6 Activity in NK Cells
Journal of Immunology,
Valentina Romeo; Sarah Gierke; Kyle A. Edgar; Scot D. Liu
The Lancet Oncology, ISSN: 14745488 14702045
Herve Tilly; Morschhauser; Nancy L. Bartlett; Amitkumar Mehta; Gilles Salles; Corinne Haioun; Javier Munoz; Andy I Chen; Kathryn S. Kolibaba; Dan Lu; Mark Yan; Elicia Penuel; Jamie Hirata; Calvin Lee; Jeff P. Sharman
Prognostic risk score for patients with relapsed or refractory chronic lymphocytic leukaemia treated with targeted therapies or chemoimmunotherapy: a retrospective, pooled cohort study with external validations
The Lancet Haematology,
Jacob D Soumerai; Ai Ni; Mohamed Darif; Anil Londhe; Guan Xing; Yong Mun; Neil E Kay; Tait D Shanafelt; Kari G Rabe; John C. Byrd; Chanan-Khan; Richard Furman; Hillmen; Jeffrey Jones; John F. Seymour; Jeff P. Sharman; Lucille Ferrante; Mehrdad Mobasher; Thomas Stark; Vijay Reddy; Lyndah K Dreiling; Pankaj Bhargava; Angela Howes; Danelle F James; Zelenetz
AAPS PharmSciTech, ISSN: 15309932
Samarth D. Thakore; Poonam Singh Thakur; Ganesh Shete; Rahul Gangwal; Ajit Narang; Abhay T. Sangamwar; Arvind Kumar Bansal
Effect of concomitant dosing with acid-reducing agents and vemurafenib dose on survival in patients with BRAFV600 mutation–positive metastatic melanoma treated with vemurafenib ± cobimetinib
European Journal of Cancer, ISSN: 09598049
Karl Lewis; Axel Hauschild; James Larkin; Antoni Ribas; Keith Flaherty; Grant A. McArthur; Brigitte Dréno; Edward McKenna; Qian Zhu; Yong Mun; Paolo A. Ascierto
Mechanisms of immune-related adverse events associated with immune checkpoint blockade: Using germline genetics to develop a personalized approach
Genome Medicine,
Zia Khan; Christian Hammer; Ellie Guardino; G. Scott Chandler; Matthew Albert
Atezolizumab plus bevacizumab versus sunitinib in patients with previously untreated metastatic renal cell carcinoma (IMmotion151): a multicentre, open-label, phase 3, randomised controlled trial
The Lancet, ISSN: 01406736
Brian I. Rini; Thomas Powles; Michael B. Atkins; Bernard Escudier; David McDermott; Cristina Suárez; Sergio Bracarda; Walter M. Stadler; Frede Donskov; Jae-Lyun Lee; Robert E. Hawkins; Alain Ravaud; Boris Alekseev; Michael D. Staehler; Motohide Uemura; Ugo De Giorgi; Begoña Mellado; Camillo Porta; Melichar; Howard Gurney; Jens Bedke; Toni K. Choueiri; Francis Parnis; Tarik Khaznadar; Alpa Thobhani; Shi Li; Elisabeth Piault-Louis; Gretchen Frantz; Mahrukh Huseni; Christina Schiff; Marjorie Green; Robert J. Motzer
Journal of Neuroscience, ISSN: 15292401
Daniel Fleck; Lilian Phu; Erik Verschueren; Trent Hinkle; Mike Reichelt; Tushar Bhangale; Benjamin Haley; Yuanyuan Wang; Rob Graham; Don Kirkpatrick; Morgan Sheng; Baris Bingol
Interlaboratory Comparison of Hydrogen-Deuterium Exchange Mass Spectrometry Measurements of the Fab Fragment of NISTmAb
Analytical Chemistry, ISSN: 00032700
Jeffrey W. Hudgens; Elyssia S. Gallagher; Ioannis Karageorgos; Kyle W. Anderson; James J. Filliben; Richard Y.-C. Huang; Guodong Chen; George M. Bou-Assaf; Alfonso Espada; Michael J. Chalmers; Eduardo Harguindey; Hui-Min Zhang; Ben Walters; Jennifer Zhang; John Venable; Caitlin Steckler; Inhee Park; Ansgar Brock; Xiaojun Lu; Ratnesh Pandey; Arun Chandramohan; Ganesh Srinivasan Anand; Sasidhar N. Nirudodhi; Justin B. Sperry; Jason C. Rouse; James A. Carroll; Kasper D. Rand; Ulrike Leurs; David D. Weis; Mohammed A. Al-Naqshabandi; Tyler S. Hageman; Daniel Deredge; Patrick L. Wintrode; Malvina Papanastasiou; John D. Lambris; Sheng Li; Sarah Urata
The Lancet Haematology, ISSN: 23523026
Steven W Pipe; Midori Shima; Michaela Lehle; Amy Shapiro; Sammy Chebon; Katsuyuki Fukutake; Nigel S. Key; Agnès Portron; Christophe Schmitt; Maria Podolak-Dawidziak; Nives Selak Bienz; Cedric Hermans; Avrita Campinha-Bacote; Anna Kiialainen; Kathelijne Peerlinck; Gallia Levy; Jiménez-Yuste
Journal of Pharmacology and Experimental Therapeutics, ISSN: 15210103
Harvey Wong; Lichuan Liu; Wenjun Ouyang; Yuzhong Deng; Matthew Wright; Marcel Hop
Cancer Chemotherapy and Pharmacology, ISSN: 14320843 03445704
Whitney P. Kirschbrown; Kagedal; Wang; Lars Lindbom; Adam Knott; Rachelle Mack; Sharareh Monemi; Ihsan Nijem; Sandhya Girish; Christie Freeman; Fumagalli; Robin McConnell; Guy Jerusalem; Chris Twelves; Baselga; Gunter Von Minckwitz; José Bines; Amit Garg
A phase 1, randomized, single-ascending-dose study to investigate the safety, tolerability, and pharmacokinetics of DSTA4637S, an anti-staphylococcus aureus thiomab antibody-antibiotic conjugate, in healthy volunteers
Antimicrobial Agents and Chemotherapy, ISSN: 00664804
Melicent Peck; Michael E. Rothenberg; Rong Deng; Nicholas Lewin-Koh; Gaohong She; Amrita Kamath; Montse Carrasco-Triguero; Ola Saad; Aide Castro; Lisa Teufel; Daniel S. Dickerson; Marisa Leonardelli; Jorge Tavel
Atezolizumab plus cobimetinib and vemurafenib in BRAF-mutated melanoma patients
Nature Medicine, ISSN: 10788956
Ryan J. Sullivan; Omid Hamid; Rene Gonzalez; Jeffery R. Infante; Manish R. Patel; F. Stephen Hodi; Karl Lewis; Hussein Tawbi; Genevive Hernandez; Matthew Wongchenko; YiMeng Chang; Louise Roberts; Marcus Ballinger; Yibing Yan; Edward Cha; Patrick Hwu
Atezolizumab with or without cobimetinib versus regorafenib in previously treated metastatic colorectal cancer (IMblaze370): a multicentre, open-label, phase 3, randomised, controlled trial
The Lancet Oncology, ISSN: 14702045
Cathy Eng; Tae Won Kim; Bendell; Guillem Argiles; Niall C. Tebbutt; Maria Di Bartolomeo; Alfredo Falcone; Marwan Fakih; Kozloff; Neil H. Segal; Alberto Sobrero; Yibing Yan; Ilsung Chang; Anne Uyei; Louise Roberts; Fortunato Ciardiello; Ahn; Jamil Asselah; Badarinath; Baijal; Begbie; Berry; Jean-Luc Canon; Carbone; Andrés Cervantes; Cha; Chang; Chaudhry; Chmielowska; Cho; Chu; Couture; Cultrera; David Cunningham; Eric Van Cutsem; Cuyle; Davies; Dowden; Dvorkin; Vinod Ganju; Garcia; Kerr; Kim; King; Kortmansky; Kozloff; Lam; Lee; Lee; Lesperance; Luppi; Ma; Evaristo Maiello; Mandanas; John Marshall; Marx; Mullamitha; Nechaeva; Park; Pavlakis; Ponce; Potemski; Raouf; James A. Reeves; Segal; Siena; Smolin; Streb; Strickland; Szutowicz-Zielinska; Tabernero; Tan; Valera; Van den Eynde; Vergauwe; Vickers; Womack; Wroblewska; Young
Coexpression of inhibitory receptors enriches for activated and functional CD8+ T cells in murine syngeneic tumor models
Cancer immunology research, ISSN: 23266066
Huizhong Xiong; Stephanie Mittman; Ryan Rodriguez; Patricia Pacheco-Sanchez; Marina Moskalenko; Yagai Yang; Justin Elstrott; Alex Ritter; Sören Müller; Dorothee Nickles; Teresita L. Arenzana; Aude-Helene Capietto; Lelia Delamarre; Zora Modrusan; Sascha Rutz; Ira Mellman; Rafael Cubas
Effects of concomitant glucocorticoids in TOZURA, a common-framework study programme of subcutaneous tocilizumab in rheumatoid arthritis
Rheumatology,
Ernest Choy; Roberto Caporali; Ricardo Xavier; Bruno Fautrel; Raimón Sanmarti; Bao; Jenny Devenport; Attila Pethö-Schramm
Genomic features of exceptional response in vemurafenib cobimetinib–treated patients with BRAFV600-mutated metastatic melanoma
Clinical Cancer Research, ISSN: 10780432
Yibing Yan; Matthew Wongchenko; Caroline Robert; James Larkin; Paolo A. Ascierto; Brigitte Dréno; Michele Maio; Claus Garbe; Paul B. Chapman; Jeffrey A. Sosman; Zhen Shi; Hartmut Koeppen; Jessie Hsu; Ilsung Chang; Ivor Caro; Isabelle Rooney; Grant A. McArthur; Antoni Ribas
In Vivo Assessment of Antibody-Dependent Enhancement of Influenza B Infection
Toxicological Sciences,
Gautham K. Rao; Rodney Prell; Steven Laing; Stefanie C M Burleson; Allen Nguyen; Jacqueline McBride; Crystal Zhang; Daniel Sheinson; Wendy Halpern
Phase I study of the indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor navoximod (GDC-0919) administered with PD-L1 inhibitor (atezolizumab) in advanced solid tumors
Clinical Cancer Research, ISSN: 10780432
Kyung Hae Jung; Patricia M. LoRusso; Howard A. Burris; Michael S. Gordon; Yung-Jue Bang; Matthew D. Hellmann; Andrés Cervantes; Maria Ochoa de Olza; Aurélien Marabelle; Stephen Hodi; Myung-Ju Ahn; Leisha A. Emens; Fabrice Barlesi; Omid Hamid; Calvo; David McDermott; Hatem Soliman; Ina Rhee; Ray Lin; Tony Pourmohamad; Julia Suchomel; Amy Tsuhako; Kari M. Morrissey; Sami Mahrus; Roland Morley; Andrea Pirzkall; Lindsey Davis
Molecular Genetics and Metabolism Reports, ISSN: 22144269
Kim R. Simpfendorfer; Wentian Li; Andrew Shih; Hongxiu Wen; Harini P. Kothari; Edward A. Einsidler; Art Wuster; Julie Hunkapiller; Tim Behrens; Rob Graham; Michael Townsend; Doron M. Behar; Rui Hu; Elliott Greenspan; Peter K. Gregersen
Cell Reports, ISSN: 22111247
Jieqiong Zhang; Webster; Debbie Dugger; Tanya Goncharov; Meron Roose-Girma; Jeffrey Hung; Youngsu Kwon; Domagoj Vucic; Kim Newton; Vishva Dixit
IRF2 transcriptionally induces GSDMD expression for pyroptosis
Science Signaling, ISSN: 19450877
Nobuhiko Kayagaki; Bettina L. Lee; Irma Stowe; Opher S. Kornfeld; Karen O'Rourke; Kathleen M. Mirrashidi; Benjamin Haley; Colin Watanabe; Meron Roose-Girma; Zora Modrusan; Sarah Kummerfeld; Rohit Reja; Yafei Zhang; Vicky Cho; Daniel Andrews; Lucy X. Morris; Christopher C. Goodnow; Edward M. Bertram; Vishva Dixit
Analytical and Bioanalytical Chemistry, ISSN: 16182650 16182642
Suk-Joon Hyung; Dongwei Li; Neelima Koppada; Surinder Kaur; Ola Saad
Organic Process Research and Development, ISSN: 1520586X 10836160
Travis Remarchuk; Remy Angelaud; David Askin; Archana Kumar; Andrew S. Thompson; Hua Cheng; John F. Reichwein; Yanping Chen; Frederic St-Jean
Organic Process Research and Development, ISSN: 1520586X 10836160
Kallakuri Suparna Rao; Frederic St-Jean; Archana Kumar
Bioconjugate Chemistry, ISSN: 15204812 10431802
Dian Su; Jinhua Chen; Ely Cosino; Josefa Dela Cruz Chuh; Helen Davis; Geoff Del Rosario; Isabel Figueroa; Leanne Goon; Jintang He; Amrita Kamath; Surinder Kaur; Kathy Kozak; Jeffrey Lau; Donna Lee; Violet Lee; Douglas Leipold; Luna Liu; Peter Liu; Guo-Liang Lu; Nelson; Carl Ng; Thomas Pillow; Paul Polakis; Andy Polson; Rebecca K. Rowntree; Ola Saad; Brian Safina; Nicola Stagg; Moana Tercel; Dick Vandlen; Breanna S. Vollmar; John Wai; Tao Wang; Binqing Wei; Keyang Xu; Juanjuan Xue; Zijin Xu; Gang Yan; Hui Yao; Shang-Fan Yu; Donglu Zhang; Fiona Zhong; Peter Dragovich
Blood, ISSN: 15280020
Marco Heestermans; Salam Salloum-Asfar; Tom Streef; El Houari Laghmani; Daniela Salvatori; Brenda M. Luken; Sacha S. Zeerleder; Henri M H Spronk; Suzanne J. Korporaal; Daniel Kirchhofer; Gerry T M Wagenaar; Henri H. Versteeg; Pieter H. Reitsma; Thomas Renné; Bart J M van Vlijmen
Hydrogen-deuterium exchange mass spectrometry (HDX-MS) centroid data measured between 3.6 oC and 25.4 OC for the Fab fragment of NiStmab
Journal of Research of the National Institute of Standards and Technology,
Jeffrey W. Hudgens; Elyssia S. Gallagher; Ioannis Karageorgos; Kyle W. Anderson; Richard Y.-C. Huang; Guodong Chen; George M. Bou-Assaf; Alfonso Espada; Michael J. Chalmers; Eduardo Harguindey; Hui-Min Zhang; Ben Walters; Jennifer Zhang; John Venable; Caitlin Steckler; Inhee Park; Ansgar Brock; Xiaojun Lu; Ratnesh Pandey; Arun Chandramohan; Ganesh Srinivasan Anand; Sasidhar N. Nirudodhi; Justin B. Sperry; Jason C. Rouse; James A. Carroll; Kasper D. Rand; Ulrike Leurs; David D. Weis; Mohammed A. Al-Naqshabandi; Tyler S. Hageman; Daniel Deredge; Patrick L. Wintrode; Malvina Papanastasiou; John D. Lambris; Sheng Li; Sarah Urata
Blood, ISSN: 15280020 00064971
Zelenetz; Gilles Salles; Kylie D. Mason; Carla Casulo; Le Gouill; Laurie H. Sehn; Herve Tilly; Guillaume Cartron; Martine E.D. Chamuleau; Andre Goy; Constantine S. Tam; Pieternella J. Lugtenburg; Adam M. Petrich; Arijit Sinha; Divya Samineni; Sylvia Herter; Ellen Ingalla; Edith Szafer-Glusman; Christian Klein; Deepak Sampath; Martin Kornacker; Mehrdad Mobasher; Morschhauser
Drug Metabolism and Disposition, ISSN: 1521009X 00909556
Shuai Wang; Buyun Chen; Peter Dragovich; Thomas Pillow; Leanna Staben; Jun Guo; Dian Su; Chenghong Zhang; Sudheer Bobba; Yong Ma; Jianshuang Wang; Dewakar Sangaraju; Binqing Wei; Gail Lewis Phillips; Cyrus Khojasteh; Donglu Zhang
The Lancet Respiratory Medicine, ISSN: 22132619 22132600
Martin Reck; Makoto Nishio; Jotte; Federico Cappuzzo; Orlandi; Daniil Stroyakovskiy; Nogami; Rodriguez-Abreu; Moro-Sibilot; Thomas; Fabrice Barlesi; Finley; Lee; Coleman; Deng; Marcin Kowanetz; Geetha Shankar; Wei Li; Mark A. Socinski; Tony S K Mok
Journal of Ocular Pharmacology and Therapeutics, ISSN: 15577732 10807683
Vladimir Bantseev; Paul E. Miller; T. Michael Nork; Carol A. Rasmussen; Aija McKenzie; Brian J. Christian; Helen Booler; Evan Thackaberry
Absence of PD-L1 expression on tumor cells in the context of an activated immune infiltrate may indicate impaired IFNγ signaling in nonsmall cell lung cancer
PLoS ONE,
Willemijn S.M.E. Theelen; Thomas Kuilman; Katja Schulze; Wei Zou; Oscar Krijgsman; Dennis D.G.C. Peters; Sten Cornelissen; Kim Monkhorst; Pranamee Sarma; Teiko Sumiyoshi; Lukas Amler; Stefan M. Willems; Johannes L.G. Blaauwgeers; Carel Jm van Noesel; Daniel S. Peeper; Michel Van Den Heuvel; Marcin Kowanetz
Stability evaluation of hydrogen peroxide uptake samples from monoclonal antibody drug product aseptically filled in vapor phase hydrogen peroxide-sanitized barrier systems: A case study
PDA Journal of Pharmaceutical Science and Technology, ISSN: 10797440
Devon Roshan Eisner; Ada Hui; Kirk Eppler; Vassia Tegoulia; Yuh-Fun Maa
AAPS Journal, ISSN: 15507416
Jinjiang Li; Mary E. Krause; Xiaodong Chen; Yuan Cheng; Weiguo Dai; John J. Hill; Min Huang; Susan Jordan; Daniel P. LaCasse; Linda O. Narhi; Evgenyi Shalaev; Ian Shieh; Justin C. Thomas; Raymond Tu; Songyan Zheng; Lily Zhu
Nature Materials, ISSN: 14764660 14761122
Barun Bhhatarai; W. Patrick Walters; Marcel Hop; Guido Lanza; Sean Ekins
Polatuzumab vedotin or pinatuzumab vedotin plus rituximab in patients with relapsed or refractory non-Hodgkin lymphoma: final results from a phase 2 randomised study (ROMULUS)
The Lancet Haematology,
Morschhauser; Ian W. Flinn; Ranjana H. Advani; Laurie H. Sehn; Catherine S. Diefenbach; Kathryn S. Kolibaba; Oliver W. Press; Gilles Salles; Herve Tilly; Andy I Chen; Sarit E. Assouline; Bruce D. Cheson; Dreyling; Anton Hagenbeek; Pier Luigi Zinzani; Surai Jones; Ji Cheng; Dan Lu; Elicia Penuel; Jamie Hirata; Michael Wenger; Yu-Waye Chu; Jeff P. Sharman
Journal of Immunological Methods, ISSN: 18727905 00221759
Lynn Kamen; Srividya Myneni; Chris Langsdorf; Elviza Kho; Ben Ordonia; Tara Thakurta; Kai Zheng; An Song; Shan Chung
British Journal of Dermatology, ISSN: 13652133 00070963
Pippa G. Corrie; Terheyden; ten Tije; Herbst; Jansen; Marples; Debus; Marconcini; Blasinska-Morawiec; Freivogel; Munson; Grant Goodman; Jessie Hsu; Natalia Sadetsky; Dawn Colburn; Piotr Rutkowski