Publications
Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.
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Murine double minute 2 inhibition alone or with cytarabine in acute myeloid leukemia: Results from an idasanutlin phase 1/1b study⋆
Leukemia Research, ISSN: 01452126
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Journal of Allergy and Clinical Immunology, ISSN: 10976825 00916749
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Curse or Cure? A Perspective on the Developability of Aldehydes as Active Pharmaceutical Ingredients
Journal of Medicinal Chemistry,
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Accurate assembly of the olive baboon (Papio anubis) genome using long-read and Hi-C data
GigaScience,
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Venetoclax-rituximab with or without bendamustine vs bendamustine-rituximab in relapsed/refractory follicular lymphoma
Blood,
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Integrated genomic analysis reveals mutated ELF3 as a potential gallbladder cancer vaccine candidate
Nature Communications, ISSN: 20411723
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Mitigating the risk of cytokine release syndrome in a Phase I trial of CD20/CD3 bispecific antibody mosunetuzumab in NHL: impact of translational system modeling
npj Systems Biology and Applications,
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Journal of Patient-Reported Outcomes, ISSN: 25098020
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Single-Cell Reconstruction of Human Basal Cell Diversity in Normal and Idiopathic Pulmonary Fibrosis Lungs
American Journal of Respiratory and Critical Care Medicine,
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Scientific Reports, ISSN: 20452322
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Nature Communications, ISSN: 20411723
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Activation of the IRE1 RNase through remodeling of the kinase front pocket by ATP-competitive ligands
Nature Communications,
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Bivalent antibody pliers inhibit β-tryptase by an allosteric mechanism dependent on the IgG hinge
Nature Communications,
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Calibrating the in vitro–in vivo correlation for OATP-mediated drug-drug interactions with rosuvastatin using static and PBPK models
Drug Metabolism and Disposition, ISSN: 00909556
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The role of polygenic risk and susceptibility genes in breast cancer over the course of life
Nature Communications,
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Scientific Reports, ISSN: 20452322
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Functional characterization of SMARCA4 variants identified by targeted exome-sequencing of 131,668 cancer patients
Nature Communications,
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Integrated digital pathology and transcriptome analysis identifies molecular mediators of T-cell exclusion in ovarian cancer
Nature Communications,
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Advances in Therapy, ISSN: 18658652 0741238X
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Scientific Reports, ISSN: 20452322
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Application of a risk-management framework for integration of stromal tumor-infiltrating lymphocytes in clinical trials
npj Breast Cancer,
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Communications Biology, ISSN: 23993642
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Nature Communications, ISSN: 20411723
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Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer
npj Breast Cancer,
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Nature Communications, ISSN: 20411723
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Drug Metabolism and Disposition, ISSN: 1521009X
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Application of a Two-Analyte Integrated Population Pharmacokinetic Model to Evaluate the Impact of Intrinsic and Extrinsic Factors on the Pharmacokinetics of Polatuzumab Vedotin in Patients with Non-Hodgkin Lymphoma
Pharmaceutical Research, ISSN: 07248741
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Development of an anti-drug antibody assay to detect anti-drug antibodies to protein and PEG in a PEGylated molecule
Bioanalysis,
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Communications Biology, ISSN: 23993642
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Pan-cancer population pharmacokinetics and exposure-safety and -efficacy analyses of atezolizumab in patients with high tumor mutational burden
Pharmacology Research and Perspectives,
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Phenotypic expression and clinical outcomes in a South Asian PRKAG2 cardiomyopathy cohort
Scientific Reports,
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Venetoclax Plus Rituximab in Relapsed Chronic Lymphocytic Leukemia: 4-Year Results and Evaluation of Impact of Genomic Complexity and Gene Mutations From the MURANO Phase III Study
Journal of Clinical Oncology,
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Nature Reviews Drug Discovery, ISSN: 14741784 14741776
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Biotechnology and Bioengineering, ISSN: 10970290 00063592
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Cell Reports, ISSN: 22111247
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Targeting Autophagy to Treat Cancer: Challenges and Opportunities
Frontiers in Pharmacology,
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Practical Early Development Synthesis of Nav17 Inhibitor GDC-0310
Synthesis (Germany), ISSN: 00397881
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Proceedings of the National Academy of Sciences of the United States of America, ISSN: 10916490 00278424
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Osteopontin Links Myeloid Activation and Disease Progression in Systemic Sclerosis
Cell Reports Medicine,
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Using differential scanning calorimetry for the development of non-reduced capillary electrophoresis sodium dodecyl sulfate methods for monoclonal antibodies
Analytical Biochemistry, ISSN: 00032697
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Frontiers in Immunology, ISSN: 16643224
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Improving Prediction of Free Fatty Acid Particle Formation in Biopharmaceutical Drug Products: Incorporating Ester Distribution during Polysorbate 20 Degradation
Molecular Pharmaceutics,
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Eye, ISSN: 14765454 0950222X
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Characterization of Tissue Distribution, Catabolism, and Elimination of an Anti-Staphylococcus aureus THIOMAB Antibody-Antibiotic Conjugate in Rats
Drug Metabolism and Disposition,
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Annals of the Rheumatic Diseases, ISSN: 14682060 00034967
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AAPS Journal, ISSN: 15507416
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Comparison of techniques to control ice nucleation during lyophilization
Processes,
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Urology, ISSN: 15279995 00904295
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Impact of Silicone Oil on Free Fatty Acid Particle Formation due to Polysorbate 20 Degradation
Pharmaceutical Research, ISSN: 07248741
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Water related impact of energy: Cost and carbon footprint analysis of water for biopharmaceuticals from tap to waste
Chemical Engineering Science: X,
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