Call Customer Service Monday through Friday, 9 am through 8pm EST at (800) 551-2231 for assistance, or find what you need here for ordering, returns and product issues.
Updated on 10/28/2025
We have resolved the technical issues with the Genentech Direct system. If you are still experiencing challenges accessing Direct ordering or Genentech Direct Returns, please try the troubleshooting steps below.
For Windows Users: to refresh your browser cache (all browsers): Press Ctrl + F5
For Mac Users: to refresh your browser cache:
 Chrome / Edge / Firefox: Press Command + Shift + R
 Safari: Press Command + R
If you prefer, you can direct your customers to call Genentech Customer Service from 9am to 8pm EST (6 am - 5 pm PST) at 1-800-551-2231.
Order deliveries may be affected due to severe weather including storms, tornados, and hurricanes sweeping through the U.S. We are monitoring the situation and will contact you directly if your order delivery is impacted.
If you have questions about the status of your order, please contact Genentech Customer Service at 1-800-551-2231 or your Channel Inventory (CIM) Manager.
The daily order deadline for next-day delivery, including small parcel Hemlibra, has been changed to 12 pm PST. Orders received after this time will be processed on the next business day.
While we strive to ship orders the next day, please be aware that we may experience delays due to our new SAP system change, and your order may arrive 1-3 days later than expected.
For product-specific quality questions:
For Tarceva
 Astellas Oncology
 Quality Department
 (800) 327-6449
Select option 2, then select the prompt for Adverse Event and Product Concerns.
All other Genentech products
 Genentech's Quality Department
 (800) 334-0290
Genentech Medical Communications:
 (800) 821-8590
For patients, caregivers and healthcare providers:
Patient Access
 We believe every person should get the Genentech medicine they need, and we offer programs to help make this happen.
 Learn More
Patient Resource Center
 Our patient resource center is dedicated to getting patients and caregivers to the right resources.
 Call us at (877) 436-3683 or (877) GENENTECH
 Monday – Friday, 6am-5pm PT
For general inquiries, please contact Legacy Pharma Inc at 1-800-727-7151.
For product returns purchased from Legacy Pharma Inc: Please contact Legacy Customer Service at [email protected] or 1-866-930-0188.
For product quality concerns, adverse events, medical inquiries, or counterfeit claims: Starting November 3, 2025, please contact Legacy Pharma Inc at [email protected] or 1-800-727-7151.