Kenta Yoshida
Distinguished Scientist, Clinical Pharmacology, Development Sciences
10
Years at Genentech
39
Publications at Genentech
6
Awards & Honors
I became part of Genentech's Clinical Pharmacology Modeling & Simulation group in 2016, following my Ph.D. in Pharmaceutical Sciences from the University of Tokyo and a postdoctoral fellowship at the FDA. Throughout my time at Genentech, I've had the chance to refine my expertise in various modeling and simulation approaches, applying them to make a meaningful impact on a wide array of clinical development projects.
Featured Publication
A mechanistic PK/PD model to enable dose selection of the potent anti-tryptase antibody (MTPS9579A) in patients with moderate-to-severe asthma.
Clin Transl Sci. 2023 Apr;16(4):694-703. doi: 10.1111/cts.13483. Epub 2023 Feb 8.
Sharon M Rymut, Lindsay M Henderson, Victor Poon, Tracy L Staton, Fang Cai, Siddharth Sukumaran, Horace Rhee, Ryan Owen, Saroja Ramanujan, Kenta Yoshida.
My Focus
My primary focuses are developing and implementing clinical pharmacology modeling and simulation strategies to optimize clinical drug development, ensuring precise drug administration aligned with patient needs. For these purposes, we perform diverse modeling & simulation approaches such as population pharmacokinetics/pharmacodynamics modeling, physiologically-based pharmacokinetic modeling, and statistical analysis including survival modeling.
Genentech Publications
npj Precision Oncology,
Matthew West; Yoshida; Jiajie Yu; Vincent Lemaire
CPT: Pharmacometrics and Systems Pharmacology, ISSN: 21638306
Kenta Yoshida; René A. Bruno; Pascal Chanu
Clinical and Translational Science, ISSN: 17528054
Victor Poon; Dhruvitkumar S. Sutaria; Prell; Wendy Halpern; Lisa Wong; Adam Harris; Justin Wilkins; Yoshida; Rucha Sane
Drug Metabolism and Disposition, ISSN: 00909556
Tomoki Koishikawa; Yukana Tomoda; Toshiaki Tsuchitani; Kunal S. Taskar; Yoshida; Jialin Mao; Tadayuki Takashima; Yurong Lai; Yuichi Sugiyama; Hiroyuki Kusuhara
Translational Vision Science and Technology, ISSN: 21642591
Yoshida; Neha Anegondi; Adam Pely; Miao Zhang; Frederic Debraine; Karthik Ramesh; Verena Steffen; Simon S. Gao; Catherine A. Cukras; Christina Rabe; Daniela Ferrara; Richard F. Spaide; Srinivas R. Sadda; Frank G. Holz; Qi Yang
Clinical Pharmacology and Therapeutics, ISSN: 15326535 00099236
Tomoki Koishikawa; Kaku Fujiwara; Kunal S. Taskar; Maciej J. Zamek-Gliszczynski; Kenta Yoshida; Xiaoyan Chu; Hideki Hirabayashi; Jialin Mao; Kevin T. Rockich; Tadayuki Takashima; Yoshiyuki Yamaura; Yurong Lai; Yukana Tomoda; Tomoko Kito; Kazuya Maeda; Kenichi Furihata; Yuichi Sugiyama; Hiroyuki Kusuhara
Clinical Pharmacology and Therapeutics, ISSN: 15326535 00099236
Joy C. Hsu; Michael Wu; Chloe J. Kim; Bianca Vora; Yi Ting Kayla Lien; Ashutosh Jindal; Kenta Yoshida; Sonoko Kawakatsu; Jeremy Gore; Jinyan Jin; Christina Lu; Bingyuan Chen; Benjamin M. Wu
CPT: Pharmacometrics and Systems Pharmacology, ISSN: 21638306
Kenta Yoshida; Victor Poon; Ajit Dash; Rebecca Kunder; Leslie Wei Chinn; Matts Kågedal
Nature Reviews Drug Discovery, ISSN: 14741784 14741776
Aleksandra Galetin; Kim L.R. Brouwer; Donald J. Tweedie; Kenta Yoshida; Noora Sjöstedt; Lauren M. Aleksunes; Xiaoyan Chu; Raymond Evers; Michael J. Hafey; Yurong Lai; Pär D. Matsson; Andrew M. Riselli; Hong Shen; Alex Sparreboom; Manthena V.S. Varma; Jia Yang; Xinning Yang; Sook Wah Yee; Maciej J. Zamek-Gliszczynski; Lei Zhang; Kathleen M. Giacomini
Allergy: European Journal of Allergy and Clinical Immunology, ISSN: 01054538
Horace Rhee; Lindsay M. Henderson; Rebecca N. Bauer; Kit Wong; Tracy Staton; David F. Choy; Prajna Banerjee; Victor Poon; Yoshida; Chen Chen; Keyi Long; Gizette Sperinde; Steven T. Laing; Nicholas Steven Jones; Sara Glickstein; Parul Dayal; Alice Fong; Ajit Dash; Grazyna Pulka; Brian Leaker; Dave Singh; Peter Bradding
British Journal of Cancer, ISSN: 15321827 00070920
René A. Bruno; Pascal Chanu; Matts Kågedal; François Mercier; Kenta Yoshida; Jérémie Y. Guedj; Chunze Li; Ulrich Beyer; Jinyan Jin
CPT: Pharmacometrics and Systems Pharmacology, ISSN: 21638306
Elise Oh; Russell D. Wada; Kha Le; Zheng; Jin Jin; Victor Poon; Kit Wong; Ryan Owen; Yoshida
Clinical and Translational Science, ISSN: 17528062 17528054
Logan Brooks; Michael J. Dolton; Jurgen Langenhorst; Yoshida; Yi Ting Lien; Vikram Malhi; Chunze Li; Pablo Perez-Moreno; John Bond; Ya-Chi Chen; Jiajie Yu
Clinical and Translational Science, ISSN: 17528062 17528054
Sharon M. Rymut; Lindsay M. Henderson; Victor Poon; Tracy Staton; Fang Cai; Siddharth Sukumaran; Horace Rhee; Ryan Owen; Ramanujan; Yoshida
JCO Clinical Cancer Informatics,
Rashed Harun; Rucha Sane; Kenta Yoshida; Dhruvitkumar S. Sutaria; Jin Y. Jin; James Lu
Clinical Cancer Research, ISSN: 15573265 10780432
Rene Bruno; Mathilde Marchand; Yoshida; Phyllis Chan; Haocheng Li; Wei Zou; François Mercier; Pascal Chanu; Benjamin Wu; Lee; Chunze Li; Jin Yan Jin; Michael Maitland; Martin Reck; Mark A. Socinski
British Journal of Clinical Pharmacology, ISSN: 13652125 03065251
Yoshida; Allan Jaochico; Jialin Mao; Dewakar Sangaraju
Clinical Pharmacology and Therapeutics, ISSN: 15326535 00099236
Xiaoyan Chu; Bhagwat Prasad; Sibylle Neuhoff; Kenta Yoshida; J. Steven Leeder; Dwaipayan Mukherjee; Kunal S. Taskar; Manthena V.S. Varma; Xinyuan Zhang; Xinning Yang; Aleksandra Galetin
Clinical Pharmacology and Therapeutics, ISSN: 15326535 00099236
Kunal S. Taskar; Xinning Yang; Sibylle Neuhoff; Mitesh Patel; Kenta Yoshida; Mary F. Paine; Kim L.R. Brouwer; Xiaoyan Chu; Yuichi Sugiyama; Jack A. Cook; Joseph W. Polli; Imad D. Hanna; Yurong Lai; Maciej J. Zamek-Gliszczynski
Clinical Pharmacology and Therapeutics, ISSN: 15326535 00099236
Tatsuki Mochizuki; Maciej J. Zamek-Gliszczynski; Kenta Yoshida; Jialin Mao; Kunal S. Taskar; Hideki Hirabayashi; Xiaoyan Chu; Yurong Lai; Tadayuki Takashima; Kevin T. Rockich; Yoshiyuki Yamaura; Kaku Fujiwara; Tadahaya Mizuno; Kazuya Maeda; Kenichi Furihata; Yuichi Sugiyama; Hiroyuki Kusuhara
Clinical and Translational Science, ISSN: 17528062 17528054
Tatsuki Mochizuki; Yasunori Aoki; Takashi Yoshikado; Kenta Yoshida; Yurong Lai; Hideki Hirabayashi; Yoshiyuki Yamaura; Kevin T. Rockich; Kunal S. Taskar; Tadayuki Takashima; Xiaoyan Chu; Maciej J. Zamek-Gliszczynski; Jialin Mao; Kazuya Maeda; Kenichi Furihata; Yuichi Sugiyama; Hiroyuki Kusuhara
AAPS Journal,
Yoshida; Phyllis Chan; Mathilde Marchand; Rong Zhang; Benjamin Wu; Ballinger; Nitzan Sternheim; Jin; Rene Bruno
Cancer Chemotherapy and Pharmacology, ISSN: 14320843 03445704
Jing Jing; Yuan Chen; Luna Musib; Jin Yan Jin; Kit Wun Kathy Cheung; Yoshida; Rucha Sane
Clinical and Translational Science, ISSN: 17528062 17528054
Sharon M. Rymut; Siddharth Sukumaran; Gizette Sperinde; Meire C. Bremer; Joshua Galanter; Yoshida; Jordan Smith; Prajna Banerjee; Viyia Sverkos; Fang Cai; Verena Steffen; Lindsay M. Henderson; Horace Rhee; Paula Belloni; Joseph Lin; Tracy Staton
Hepatology, ISSN: 15273350 02709139
Chin Wong; Ajit Dash; Jill Fredrickson; Nicholas Lewin-Koh; Shan Chen; Kenta Yoshida; Yanqiu Liu; Johnny Gutierrez; Rebecca Kunder
Cancer Chemotherapy and Pharmacology, ISSN: 03445704
Naoki Kotani; Justin Wilkins; Janet R. Wade; Steve Dang; Dhruvitkumar S. Sutaria; Kenta Yoshida; Sameer Sundrani; Hao Ding; Josep Garcia; Heather Hinton; Rucha Sane; Pascal Chanu
Journal of Clinical Pharmacology, ISSN: 15524604 00912700
Kenta Yoshida; Justin J. Wilkins; Julia Winkler; Janet R. Wade; Naoki Kotani; Nina Wang; Rucha S. Sane; Pascal Chanu
CPT: Pharmacometrics and Systems Pharmacology, ISSN: 21638306
Phyllis Chan; Mathilde Marchand; Yoshida; Shweta Vadhavkar; Nina Wang; Alyse Lin; Benjamin Wu; Ballinger; Nitzan Sternheim; Jin Yan Jin; Rene Bruno
CPT: Pharmacometrics and Systems Pharmacology, ISSN: 21638306
Yuan Chen; Fang Ma; Nicholas Steven Jones; Yoshida; Po-Chang Chiang; Matthew Durk; Matthew Wright; Jin Yan Jin; Leslie Chinn
Alzheimer's Research and Therapy, ISSN: 17589193
Yoshida; Anita Moein; Tobias Bittner; Ostrowitzki; Helen Lin; Lee Honigberg; Jin Y. Jin; Angelica Quartino
Clinical Pharmacology and Therapeutics, ISSN: 15326535 00099236
Nicholas Steven Jones; Yoshida; Laurent Salphati; Jane R. Kenny; Matthew Durk; Leslie Chinn
Drug Metabolism and Disposition, ISSN: 1521009X 00909556
Kit Wun Kathy Cheung; Yoshida; Sravanthi Cheeti; Buyun Chen; Roland Morley; Iris Chan; Srikumar Sahasranaman; Lichuan Liu
Journal of Clinical Pharmacology, ISSN: 15524604 00912700
Lichuan Liu; Sravanthi Cheeti; Yoshida; Edna F. Choo; Eugene C. Chen; Buyun Chen; Mary Gates; Stina M. Singel; Roland Morley; Joseph A. Ware; Srikumar Sahasranaman
Clinical Pharmacology and Therapeutics, ISSN: 15326535 00099236
Xiaoyan Chu; Mingxiang Liao; Hong Shen; Kenta Yoshida; Arik A. Zur; Vikram Arya; Aleksandra Galetin; Kathleen M. Giacomini; Imad D. Hanna; Hiroyuki Kusuhara; Yurong Lai; Amilcar David Rodrigues; Yuichi Sugiyama; Maciej J. Zamek-Gliszczynski; Lei Zhang
CPT: Pharmacometrics and Systems Pharmacology, ISSN: 21638306
Kenta Yoshida; Cen Guo; Rucha S. Sane
Clinical Pharmacology and Therapeutics, ISSN: 15326535 00099236
Mohamad Shebley; Punam Sandhu; Arian Emami-Riedmaier; Masoud Jamei; Rangaraj Narayanan; Aarti H. Patel; Sheila Annie Peters; Venkatesh Pilla-Reddy; Ming Zheng; Loeckie L. de Zwart; Maud Bénéton; François Bouzom; Jun Chen; Yuan Chen; Yumi Cleary; Christiane Collins; Gemma L. Dickinson; Nassim Djebli; Heidi J. Einolf; Iain B. Gardner; Felix Huth; Faraz Kazmi; Feras Khalil; Jing Lin; Aleksandrs Odinecs; Chirag G. Patel; Haojing Rong; Edgar L. Schuck; Pradeep Sharma; Shupei Wu; Yang Xu; Shinji Yamazaki; Kenta Yoshida; Malcolm M. Rowland
Clinical Pharmacology and Therapeutics, ISSN: 15326535 00099236
Mingliang Tan; Kenta Yoshida; Ping Zhao; Lei Zhang; Thomas D. Nolin; Micheline Piquette-Miller; Aleksandra Galetin; Shiew Mei Huang
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Dinko Rekic; Kellie Schoolar Reynolds; Ping Zhao; Lei Zhang; Kenta Yoshida; Madhav Sachar; Micheline Piquette-Miller; Shiew Mei Huang; Issam Zineh
Clinical Pharmacology and Therapeutics, ISSN: 15326535 00099236
Yoshida; Nageshwar Budha; Jin Y. Jin
Education
- Graduate School of Pharmaceutical Sciences, The University of Tokyo, Japan, Ph.D. in Pharmaceutical Sciences – 2014
- Graduate School of Pharmaceutical Sciences, The University of Tokyo, Japan, Master of Pharmaceutical Sciences – 2011
- Faculty of Pharmaceutical Sciences, The University of Tokyo, Japan, Bachelor of Pharmaceutical Sciences – 2009
Awards & Honors
- Hartmut Derendorf Young Scientists Award, 13th Marbach Castle DDI Workshop – 2023
- International Society of Pharmacometrics (ISoP) Outstanding Research Manuscript Award – 2019
- International Society of Pharmacometrics (ISoP) Unsung Hero Award – 2019
- ASCPT Pharmacometrics Skills Competition finalist (professional team category) – 2018
- Best Presentation Award First Prize, Japanese Society for Alternative to Animal Experiments – 2012
- APSTJ Global Education Seminar Presentation Award 2012, Academy of Pharmaceutical Science and Technology, Japan – 2012