Lyndsay Murrow
Principal Scientist Single Cell Genomics, Cellular and Tissue Genomics, Research Biology
"I come to work every day motivated by the opportunity to make a real difference in patients’ lives, and inspired by the colleagues and collaborators that make Genentech a truly special place."
I joined CTG Oncology, in the Department of Cellular and Tissue Genomics, in 2022. My lab focuses on applying and developing high-resolution technologies and computational tools for target discovery, with a focus on breast cancer and tumor- microenvironment interactions. During my postdoctoral training at UCSF, I studied how hormone signaling across menstrual cycles coordinates cell growth and remodeling at the tissue-scale in the human breast. As part of this work, I co-developed computational (DoubletFinder, DECIPHERseq) and experimental (MULTIseq) tools where needed to further biological insights.
At Genentech, I am excited to apply this expertise to projects that can directly impact patients, and to pursue cross-functional projects with collaborators across functional domains including research oncology, translational/biomarker research, computational biology, and ML/AI.
Postdoctoral Mentor
My postdoctoral training shaped me into the scientist I am today. I am excited to provide that same opportunity to the next generation of scientists who want to understand disease biology to improve patient outcomes.
Featured Publication
Mapping hormone-regulated cell-cell interaction networks in the human breast at single-cell resolution.
Cell Systems, 2022
DoubletFinder: doublet detection in single-cell RNA sequencing data using artificial nearest neighbors.
Cell Systems, 2019