Mike Costa - Senior Scientist, Discovery Oncology

Mike Costa

Senior Scientist, Discovery Oncology

"I am inspired by my daily interactions here with like-minded scientists driven by a passion for discovery and commitment to translating a deeper understanding of biologic processes into novel disease therapies."
13
Years at Genentech
13
Publications
3
Awards & Honors

I transitioned to Genentech in 2004 to extend my research focus from invertebrate genetics of developmental pathways to signal transduction biology in mammalian cancer models. Previously I led a C. elegans genetics group at Exelixis that identified novel regulators in several signaling pathways. At Genentech, a critical mass of talented scientists and extensive resources provide for a collaborative research environment that enables discovery of novel molecular mechanisms driving human diseases and translation of these discoveries into targeted therapies. I am inspired by my daily interactions here with like-minded scientists driven by a passion for discovery and commitment to translating a deeper understanding of biological processes into novel disease therapies.

Featured Publication

A Novel Tankyrase Small-Molecule Inhibitor Suppresses APC Mutation-Driven Colorectal Tumor Growth.

Cancer Res. 2013 May 15;73(10):3132-3144.

Lau T, Chan E, Callow M, Waaler J, Boggs J, Blake RA, Magnuson S, Sambrone A, Schutten M, Firestein R, Machon O, Korinek V, Choo E, Diaz D, Merchant M, Polakis P, Holsworth DD, Krauss S, Costa M.