Sally Fischer
Distinguished Scientist, Senior Director and Senior Fellow, BioAnalytical Sciences, Assay Development and Technology, Development Sciences
Fellow
"Genentech is an incredibly innovative and rewarding place to work. During my time here, I have had the privilege to contribute to multiple projects and have interacted with many incredibly dedicated, smart and talented scientists. I am inspired every day by knowing that our efforts in addressing unmet medical needs may have a positive impact on patient lives."
25
Years at Genentech
54
Publications at Genentech
I joined Genentech in May 2000 as a Scientist contributing to the small molecule discovery effort. In 2003 I had the opportunity to join the Development Sciences department and learn about drug development. I am a Protein Scientist by training so was fascinated by our antibody therapeutic portfolio and was thrilled to be able to contribute to this effort. I am currently a Principal Scientist and Group Leader in the Assay Development and Technology group within the BioAnalytical Sciences department. The members of my team are integrated into various project teams and are responsible for development of assay strategies and methods to evaluate the pharmacokinetics (PK), anti-therapeutic antibodies as well as biomarkers to support our studies and enable filing of IND, BLA, NDA and related filings. Our focus is to provide data that will potentially enable development of novel therapeutics in both immunology and neuroscience therapeutic areas.
Featured Publication
The assay design used for measurement of therapeutic antibody concentrations can affect pharmacokinetic parameters: Case studies.
MAbs. 2012 Sep-Oct;4(5):623-31
Fischer SK, Yang J, Anand B, Cowan K, Hendricks R, Li J, Nakamura G, Song A.
My Focus
Data generated from a study can only be as good as the bioanalytical strategy and methods used to generate them. Development of bioanalytical methods have become increasingly more challenging with new therapeutic areas/patient populations as well as when developing novel engineered molecules. My focus is to ensure we have the right tools and strategies for our work across Genentech Research and Early Development (gRED). I lead the gIANT (gRed Immunoassay Novel Technology) forum that focuses on evaluation of novel and emerging immunoassay technologies and their implementation across gRED.
Genentech Publications
AAPS Journal,
Gizette Sperinde; Yenny Webb-Vargas; Zicheng Hu; Ashis Saha; Christian Hammer; Rich Erickson; Christopher Eden; Deanna Galloway; Rhian Jacob-Moffatt; Ketevan A. Siradze; Van Nguyen; Saloumeh Kadkhodayan Fischer
Bioanalysis, ISSN: 17576199 17576180
Saloumeh Kadkhodayan Fischer; Xiaome Xu; Hayeun Ji; Bingqing Zhang; Jeongsup Shim
Journal of Pharmaceutical and Biomedical Analysis, ISSN: 07317085
Xiaoyun Yang; Evelin Logis; Kathi Williams; X Rebecca Sheng; Saloumeh Kadkhodayan Fischer
Journal of Pharmaceutical and Biomedical Analysis, ISSN: 07317085
Hao Li; Alejandro R Foley; Jeongsup Shim; Ketevan A. Siradze; Yenny Webb-Vargas; Gizette Sperinde; Saloumeh Kadkhodayan Fischer
Bioanalysis,
Alejandro R. Foley; Gizette Sperinde; Saloumeh Kadkhodayan Fischer
AAPS Journal,
Audrey Arjomandi; Ketevan A. Siradze; Melissa Cheu; Teresa Davancaze; Rajbharan Yadav; Gautham K. Rao; Lisa Wong; Saloumeh Kadkhodayan Fischer
AAPS Journal,
Maoyin Li; Audrey Arjomandi; Xiaowei Sun; Erhu Lu; Tulika Tyagi; WeiYu Lin; Saloumeh Kadkhodayan Fischer; Surinder Kaur; Keyang Xu
Clinical Pharmacology and Therapeutics, ISSN: 00099236
Sandhya Mandlekar; Dhruvitkumar S. Sutaria; Xiaoyun Yang; Ryan Johnson; Yixuan Zou; Brian J. Dean; Liuxi Chen; Rucha Sane; Kathi Williams; Alison Cardenas; Mary Simon; Saloumeh Kadkhodayan Fischer
Bioanalysis,
Xiaoyun Yang; Kathi Williams; Rebecca Elliott; Martha Hokom; Janis Allen; Saloumeh Kadkhodayan Fischer
Bioanalysis,
Gizette Sperinde; Michael J. Dolton; Wenhui Zhang; Joel Mathews; Wendy Putnam; Saloumeh Kadkhodayan Fischer
Journal of Immunological Methods, ISSN: 00221759
Xiaoyun Yang; Ketevan A. Siradze; Gizette Sperinde; Audrey Arjomandi; Saloumeh Kadkhodayan Fischer
AAPS Journal,
Jeongsup Shim; Jessica Chen; Montserrat Carrasco-Triguero; Saloumeh Kadkhodayan Fischer
EBioMedicine,
Amit Bar-Or; Gian-Andrea Thanei; Chris Harp; Corrado Bernasconi; Ulrike Bonati; Anne Cross; Saloumeh Kadkhodayan Fischer; Laura Gaetano; Stephen L. Hauser; Robert Hendricks; Ludwig Kappos; Jens Kuhle; Leppert; Fabian Model; Sauter; Harold Koendgen; Xiaoming Jia; Ann E. Herman
AAPS Journal, ISSN: 15507416
A F. Setiadi; Gizette Sperinde; Melissa Cheu; Wei-Ching Liang; WeiYu Lin; Connie Mahood; Saloumeh Kadkhodayan Fischer
Bioanalysis, ISSN: 17576199 17576180
Gizette Sperinde; Luna Liu; Keyang Xu; Tracy Bentley; Sid Sukumaran; Jeff Lutman; Catherine Huang; Kathi Williams; Martha Hokom; Saloumeh Kadkhodayan Fischer
Bioanalysis, ISSN: 17576199 17576180
Kathi Williams; Jeff Lutman; Cynthia McCaughey; Saloumeh Kadkhodayan Fischer
Bioanalysis, ISSN: 17576199 17576180
Kun Peng; Ketevan A. Siradze; Saloumeh Kadkhodayan Fischer
Bioanalysis, ISSN: 17576199 17576180
Saloumeh Kadkhodayan Fischer; Kathi Williams; Ian Harmon; Bryan Bothwell; Hua Xu; Emmanuel Capio; Mikhail Briman
Bioanalysis, ISSN: 17576199 17576180
Gizette Sperinde; Meire C. Bremer; Henry R. Maun; Amos Baruch; Lazarus; James T. Koerber; Rajesh Vij; Tangsheng Yi; Saloumeh Kadkhodayan Fischer; Tracy Staton
Bioanalysis, ISSN: 17576199 17576180
Saloumeh Kadkhodayan Fischer
Bioanalysis, ISSN: 17576199 17576180
Saloumeh Kadkhodayan Fischer; Kathi Williams; Ling Wang; Emmanuel Capio; Mikhail Briman
Bioanalysis, ISSN: 17576199 17576180
Robert Hendricks; Baker; Jochen Brumm; Teresa Davancaze; Chris Harp; Ann E. Herman; H-Christian von Büdingen; Michael J. Townsend; Saloumeh Kadkhodayan Fischer
mAbs, ISSN: 19420870 19420862
Shan Chung; Van Nguyen; Yuwen L. Lin; Julien Lafrance-Vanasse; Suzie J. Scales; Kevin Lin; Rong Deng; Kathi Williams; Gizette Sperinde; Juan Jenny Li; Kai Zheng; Siddharth Sukumaran; Devin B. Tesar; James A. Ernst; Saloumeh Kadkhodayan Fischer; Greg A. Lazar; Saileta Prabhu; An Song
Bioanalytical challenges in development of ultrasensitive Home Brew assays: A case study using IL-13
Bioanalysis, ISSN: 17576199 17576180
Gizette Sperinde; Martha Hokom; Kun Peng; Saloumeh Kadkhodayan Fischer
Bioanalysis, ISSN: 17576199 17576180
Brian Booth; Lauren Stevenson; Renuka Pillutla; Michael H. Buonarati; Chris Beaver; Daniela Fraier; Fabio Garofolo; Sam Haidar; Rafiqul Islam; Christopher James; John Kadavil; Olga Kavetska; Li; Christina Satterwhite; Natasha Savoie; Sriram Subramaniam; Nilufer Tampal; Theingi Thway; Eric Woolf; Olivier Le Blaye; Matthew Andisik; Chad Briscoe; Stephanie Cape; Arindam Dasgupta; Saloumeh Kadkhodayan Fischer; Roger Hayes; John Kamerud; Gustavo Mendes Lima Santos; Corey Nehls; Catherine Soo; Stephen Vinter; Emma Whale; Keyang Xu; Seongeun Julia Cho; Anna Edmison; Sean Kassim; Thais Correa Rocha; Jan Welink; Shashi Amur; Abbas Bandukwala; Elana Cherry; Shirley Hopper; Akiko Ishii-Watabe; Susan Kirshner; Kevin Maher; Joao Pedras-Vasconcelos; Yoshiro Saito; Therese Solstad Saunders; Venke Skibeli; Verthelyi; Yow-Ming C. Wang; Haoheng Yan
AAPS Journal, ISSN: 15507416
Kun Peng; Yehong Wang; Ketevan A. Siradze; Erickson; Saloumeh Kadkhodayan Fischer; Tracy Staton
Bioanalysis, ISSN: 17576199 17576180
Lauren Stevenson; Richards; Renuka Pillutla; Albert Torri; John Kamerud; Devangi Mehta; Steve Keller; Shobha Purushothama; Boris Gorovits; Virginia Litwin; Christopher C. Stebbins; Joseph Marini; Chris Beaver; Gizette Sperinde; Patricia Siguenza; Roland F Staack; Yongchang Qiu; Lakshmi Amaravadi; Shashi Amur; Catherine Aversa Fleener; Daniel Baltrukonis; Ian Catlett; Elana Cherry; Shan Chung; Isabelle Cludts; Lorella Di Donato; Saloumeh Kadkhodayan Fischer; Stephanie Fraser; Fabio Garofolo; Cherie Green; George R. Gunn; Sam Haidar; Jonathan Haulenbeek; Neil Henderson; Shirley Hopper; Akiko Ishii-Watabe; Rafiqul Islam; Brian Janelsins; Vibha Jawa; Vellalore Kakkanaiah; Szilard Kamondi; Gerry Kolaitis; Robert J Kubiak; Seema Kumar; Pekka Kurki; Meina Liang; Patrick Liu; Kimberly Maxfield; Heather Myler; Nisha Palackal; Rachel Palmer; Joao Pedras-Vasconcelos; Steven Piccoli; Paul Rhyne; Yoshiro Saito; Natasha Savoie; Eginhard Schick; Becky Schweighardt; Judy Shih; An Song; Priya Sriraman; Ludovicus Staelens; Giane Sumner; Yongliang Sun; Martin Ullmann; Verthelyi; Meenu Wadhwa; Yow-Ming C. Wang; Yuanxin Xu; Haoheng Yan; Tong-Yuan Yang; Rong Zeng
AAPS Journal, ISSN: 15507416
Allison Given Chunyk; Alison Joyce; Saloumeh Kadkhodayan Fischer; Mark Dysinger; Alvydas Mikulskis; Andreas Jeromin; Rosemary Lawrence-Henderson; Baker; David Yeung
Bioanalysis, ISSN: 17576199 17576180
Shalini Gupta; Richards; Lakshmi Amaravadi; Steven Piccoli; Binodh DeSilva; Renuka Pillutla; Lauren Stevenson; Devangi Mehta; Montserrat Carrasco-Triguero; Robert J. Neely; Michael A. Partridge; Roland F Staack; Xuemei Zhao; Boris Gorovits; Gerry Kolaitis; Giane Sumner; Kay Stubenrauch; Zou; Shashi Amur; Chris Beaver; Isabella Berger; Flora Berisha; Herbert Birnboeck; Joe Bower; Seongeun Julia Cho; Isabelle Cludts; Cocea; Lorella Di Donato; Saloumeh Kadkhodayan Fischer; Stephanie Fraser; Fabio Garofolo; Sam Haidar; Jonathan Haulenbeek; Charles Hottenstein; Jenny Hu; Akiko Ishii-Watabe; Rafiqul Islam; Darshana Jani; John Kadavil; John Kamerud; Daniel Kramer; Pekka Kurki; Stephen MacMannis; Jim McNally; Ashley Mullan; Apollon Papadimitriou; Joao Pedras-Vasconcelos; Soma Ray; Afshin Safavi; Yoshiro Saito; Natasha Savoie; Marianne Scheel Fjording; Kara Scheibner; John Smeraglia; An Song; Bruce C. Stouffer; Nilufer Tampal; Barry Van Der Strate; Thorsten Verch; Jan Welink; Yuanxin Xu; Tong-Yuan Yang; Lilian Yengi; Jianing Zeng; Yan Zhang; Yanhua Zhang; Stephen Zoog
Bioanalysis, ISSN: 17576199 17576180
Saloumeh Kadkhodayan Fischer
Bioanalysis, ISSN: 17576199 17576180
Kathi Williams; Erickson; Saloumeh Kadkhodayan Fischer
AAPS Journal, ISSN: 15507416
Saloumeh Kadkhodayan Fischer; Melissa Cheu; Kun Peng; John Lowe; James Araujo; Elaine R. Murray; Mcclintock; Matthews; Patricia Siguenza; An Song
Bioanalysis, ISSN: 17576199 17576180
Saloumeh Kadkhodayan Fischer; Montserrat Carrasco-Triguero; Kyu Hong; Jeremy Good; Teresa Davancaze; Trung Nguy; Jessica Li; Darbonne; Alyssa M. Morimoto; Yuda Zhu
Bioanalysis, ISSN: 17576199 17576180
Cheryl A. Schofield; Saloumeh Kadkhodayan Fischer; Michael J. Townsend; Mosesova; Kun Peng; A F. Setiadi; An Song; Amos Baruch
The Lancet Respiratory Medicine, ISSN: 22132619 22132600
Nicola A. Hanania; Phillip Korenblat; Kenneth R Chapman; Eric D Bateman; Petr Kopecky; Pierluigi Paggiaro; Akihito Yokoyama; Julie Olsson; Sarah Gray; Cécile T.J. Holweg; Mark D. Eisner; Charles Asare; Saloumeh Kadkhodayan Fischer; Kun Peng; Wendy Putnam; Matthews
AAPS Journal, ISSN: 15507416
Baker; Nakamura; Henry B. Lowman; Saloumeh Kadkhodayan Fischer
Journal of Biological Chemistry, ISSN: 1083351X 00219258
Daniela Bumbaca; Vikas Sharma; C. Andrew Boswell; Isidro Hötzel; Devin B. Tesar; Yonglei Shang; Yong Ying; Saloumeh Kadkhodayan Fischer; Jane L. Grogan; Eugene Y. Chiang; Konnie Urban; Sheila Ulufatu; Leslie A. Khawli; Saileta Prabhu; Sean B. Joseph; Robert F. Kelley
Thorax, ISSN: 14683296 00406376
Nicola A. Hanania; Michael Noonan; Jonathan Corren; Phillip Korenblat; Zheng; Saloumeh Kadkhodayan Fischer; Melissa Cheu; Wendy Putnam; Elaine R. Murray; Heleen Scheerens; Cécile T.J. Holweg; Romeo MacIuca; Sarah Gray; Ramona Doyle; Mcclintock; Julie Olsson; Matthews; Karl Yen
Bioanalysis, ISSN: 17576199 17576180
Zhihua Julia Qiu; Yong Ying; Sock-Cheng Lewin-Koh; Daniel A. Coleman; Suzanne Brignoli; Robert Hendricks; Patricia Siguenza; Quarmby; Saloumeh Kadkhodayan Fischer; An Song
AAPS Journal, ISSN: 15507416
Saloumeh Kadkhodayan Fischer; Alison Joyce; Mark Spengler; Tong-Yuan Yang; Yao Zhuang; Marianne Scheel Fjording; Alvydas Mikulskis
mAbs, ISSN: 19420870 19420862
Kun Peng; Keyang Xu; Luna Liu; Robert Hendricks; Reginald Delarosa; Erickson; Nageshwar Budha; Maya Leabman; An Song; Surinder Kaur; Saloumeh Kadkhodayan Fischer
Current Medical Research and Opinion, ISSN: 14734877 03007995
Baker; Kun Peng; Melissa Cheu; Saloumeh Kadkhodayan Fischer
Arthritis Research and Therapy, ISSN: 14786362 14786354
Glynn Dennis Jr; Cécile T.J. Holweg; Sarah K. Kummerfeld; David F. Choy; A F. Setiadi; Jason A. Hackney; Matthias Peter; Houston N. Gilbert; Wei Lin; Laurie Diehl; Saloumeh Kadkhodayan Fischer; An Song; David Musselman; Micki Klearman; Cem Gabay; Arthur Kavanaugh; Judith Endres; David A. Fox; Flavius Martin; Michael J. Townsend
Current Medical Research and Opinion, ISSN: 14734877 03007995
Baker; Kun Peng; Melissa Cheu; Saloumeh Kadkhodayan Fischer
AAPS Journal, ISSN: 15507416
Kun Peng; Baker; Suzanne Brignoli; Janis Cabuhat; Saloumeh Kadkhodayan Fischer
mAbs, ISSN: 19420862 19420870
Deborah L. Mortensen; Saileta Prabhu; Stefanich; Saloumeh Kadkhodayan Fischer; Thomas R. Gelzleichter; Baker; Jenny Jiang; Kristin Wallace; Suhasini Iyer; Fielder; Wendy Putnam
Bioanalysis, ISSN: 17576180 17576199
Kyra J. Cowan; Erickson; Brian Sue; Reginald Delarosa; Bert Gunter; Daniel A. Coleman; Houston N. Gilbert; An Song; Saloumeh Kadkhodayan Fischer
mAbs, ISSN: 19420862 19420870
Saloumeh Kadkhodayan Fischer; Yang; Banmeet S. Anand; Kyra J. Cowan; Robert Hendricks; Jing Li; Nakamura; An Song
AAPS Journal, ISSN: 15507416
Frank P. Spriggs; Zhandong Don Zhong; Afshin Safavi; Darshana Jani; Narasaiah Dontha; Anita Kant; Jenny Ly; Lia Brilando; Karolina Österlund; Nathalie Rouleau; Saloumeh Kadkhodayan Fischer; Martin Boissonneault; Chad Ray
Journal of Pharmaceutical and Biomedical Analysis, ISSN: 07317085 1873264X
James Araujo; Marcel Zocher; Kristin Wallace; Kun Peng; Saloumeh Kadkhodayan Fischer
Journal of Pharmaceutical and Biomedical Analysis, ISSN: 07317085
Kun Peng; Ketevan A. Siradze; Quarmby; Saloumeh Kadkhodayan Fischer
Clinical Pharmacology and Therapeutics, ISSN: 00099236 15326535
Zheng; Heleen Scheerens; John C. Davis; Rong Deng; Saloumeh Kadkhodayan Fischer; Cynthia Woods; Fielder; Stefanich
AAPS Journal, ISSN: 15507416
Wendy Putnam; Jing Li; Jonas Haggstrom; Chee Ng; Saloumeh Kadkhodayan Fischer; Melissa Cheu; Yamo Deniz; Henry B. Lowman; Fielder; Jennifer Visich; Amita Joshi; Nelson L'ntshotsholé Jumbe
Assay and Drug Development Technologies, ISSN: 1540658X
Saloumeh Kadkhodayan Fischer; Linda O. Elliott; Grace Mausisa; Heidi J. A. Wallweber; Deshayes; Bainian Feng; Wayne J. Fairbrother
Education
- University of South Carolina, Ph.D. in Biochemistry – 1992