Sally Fischer
Principal Scientist, BioAnalytical Sciences, Assay Development and Technology, Department of Development Sciences
"Genentech is an incredibly innovative and rewarding place to work. During my time here, I have had the privilege to contribute to multiple projects and have interacted with many incredibly dedicated, smart and talented scientists. I am inspired every day by knowing that our efforts in addressing unmet medical needs may have a positive impact on patient lives."
19
Years at Genentech
28
Publications
I joined Genentech in May 2000 as a Scientist contributing to the small molecule discovery effort. In 2003 I had the opportunity to join the Development Sciences department and learn about drug development. I am a Protein Scientist by training so was fascinated by our antibody therapeutic portfolio and was thrilled to be able to contribute to this effort. I am currently a Principal Scientist and Group Leader in the Assay Development and Technology group within the BioAnalytical Sciences department. The members of my team are integrated into various project teams and are responsible for development of assay strategies and methods to evaluate the pharmacokinetics (PK), anti-therapeutic antibodies as well as biomarkers to support our studies and enable filing of IND, BLA, NDA and related filings. Our focus is to provide data that will potentially enable development of novel therapeutics in both immunology and neuroscience therapeutic areas.
Featured Publication
The assay design used for measurement of therapeutic antibody concentrations can affect pharmacokinetic parameters: Case studies.
MAbs. 2012 Sep-Oct;4(5):623-31
Fischer SK, Yang J, Anand B, Cowan K, Hendricks R, Li J, Nakamura G, Song A.
My Focus
Data generated from a study can only be as good as the bioanalytical strategy and methods used to generate them. Development of bioanalytical methods have become increasingly more challenging with new therapeutic areas/patient populations as well as when developing novel engineered molecules. My focus is to ensure we have the right tools and strategies for our work across Genentech Research and Early Development (gRED). I lead the gIANT (gRed Immunoassay Novel Technology) forum that focuses on evaluation of novel and emerging immunoassay technologies and their implementation across gRED.
Publications
AAPS Journal, ISSN: 15507416
Kate Peng; Yehong Wang; Ketevan Siradze; Rich Erickson; Sally Fischer; Tracy Staton
mAbs, ISSN: 19420870 19420862
Shan Chung; Van Nguyen; Linda Lin; Julien Lafrance-Vanasse; Suzie Scales; Kevin Lin; Rong Deng; Kathi Williams; Gizette Sperinde; Juan Jenny Li; Kai Zheng; Sid Sukumaran; Devin Tesar; James A. Ernst; Sally Fischer; Greg Lazar; Saileta Prabhu; An Song
Bioanalytical challenges in development of ultrasensitive Home Brew assays: A case study using IL-13
Bioanalysis, ISSN: 17576199 17576180
Gizette Sperinde; Martha Hokom; Kate Peng; Sally Fischer
Bioanalysis, ISSN: 17576199 17576180
Lauren Stevenson; Richards; Renuka Pillutla; Albert Torri; John Kamerud; Devangi Mehta; Stephen Keller; Shobha Purushothama; Boris Gorovits; Virginia Litwin; Christopher Stebbins; Joseph Marini; Chris Beaver; Gizette Sperinde; Patty Siguenza; Roland F Staack; Yongchang Qiu; Lakshmi Amaravadi; Shashi Amur; Catherine Aversa Fleener; Daniel Baltrukonis; Ian Catlett; Elana Cherry; Shan Chung; Isabelle Cludts; Lorella Di Donato; Sally Fischer; Stephanie Fraser; Fabio Garofolo; Cherie Green; George R. Gunn; Sam Haidar; Jonathan Haulenbeek; Neil Henderson; Shirley Hopper; Akiko Ishii-Watabe; Rafiq Islam; Brian Janelsins; Vibha Jawa; Vellalore Kakkanaiah; Szilard Kamondi; Gerry Kolaitis; Robert J Kubiak; Seema Kumar; Pekka Kurki; Meina Liang; Patrick Liu; Kimberly Maxfield; Heather Myler; Nisha Palackal; Rachel Palmer; Joao Pedras-Vasconcelos; Steven Piccoli; Paul Rhyne; Yoshiro Saito; Natasha Savoie; Eginhard Schick; Becky Schweighardt; Judy Shih; An Song; Priya Sriraman; Ludovicus Staelens; Giane Sumner; Yongliang
AAPS Journal, ISSN: 15507416
Allison Given Chunyk; Alison Joyce; Sally Fischer; Mark Dysinger; Alvydas Mikulskis; Andreas Jeromin; Rosemary Lawrence-Henderson; Dana Baker; David Yeung
Bioanalysis, ISSN: 17576199 17576180
Shalini Gupta; Richards; Lakshmi Amaravadi; Steven Piccoli; Binodh DeSilva; Renuka Pillutla; Lauren Stevenson; Devangi Mehta; Montse Carrasco-Triguero; Robert J. Neely; Michael A. Partridge; Roland F Staack; Xuemei Zhao; Boris Gorovits; Gerry Kolaitis; Giane Sumner; Kay Stubenrauch; Zou; Shashi Amur; Chris Beaver; Isabella Berger; Flora Berisha; Herbert Birnboeck; Joe Bower; Seongeun Julia Cho; Isabelle Cludts; Cocea; Lorella Di Donato; Sally Fischer; Stephanie Fraser; Fabio Garofolo; Sam Haidar; Jonathan Haulenbeek; Charles Hottenstein; Jenny Hu; Akiko Ishii-Watabe; Rafiq Islam; Darshana Jani; John Kadavil; John Kamerud; Daniel Kramer; Pekka Kurki; Stephen MacMannis; Jim McNally; Ashley Mullan; Apollon Papadimitriou; Joao Pedras-Vasconcelos; Soma Ray; Afshin Safavi; Yoshiro Saito; Natasha Savoie; Marianne Scheel Fjording; Kara Scheibner; John Smeraglia; An Song; Bruce C. Stouffer; Nilufer Tampal; Barry Van Der Strate; Thorsten Verch; Jan Welink; Yuanxin Xu; Tong-Yuan Yang; Lilian Yengi; Jianing Zeng; Yan
Bioanalysis, ISSN: 17576199 17576180
Sally Fischer
Bioanalysis, ISSN: 17576199 17576180
Kathi Williams; Rich Erickson; Sally Fischer
AAPS Journal, ISSN: 15507416
Sally Fischer; Melissa Cheu; Kate Peng; John Lowe; James Araujo; Elaine Murray; Mcclintock; John Matthews; Patty Siguenza; An Song
Bioanalysis, ISSN: 17576199
Cheryl Schofield; Sally Fischer; Michael Townsend; Sofia Mosesova; Kate Peng; Francesca Setiadi; An Song; Amos Baruch
Bioanalysis, ISSN: 17576199
Sally Fischer; Montse Carrasco-Triguero; Kyu Hong; Jeremy Good; Teresa Davancaze; Trung Nguy; Jessica Li; Walter Darbonne; Alyssa Morimoto; Yuda Zhu
The Lancet Respiratory Medicine, ISSN: 22132619
Nicola A. Hanania; Phillip Korenblat; Kenneth R Chapman; Eric D Bateman; Petr Kopecky; Pierluigi Paggiaro; Akihito Yokoyama; Julie Olsson; Sarah Gray; Cecile Holweg; Mark Eisner; Charles Asare; Sally Fischer; Kate Peng; Wendy Putnam; John Matthews
AAPS Journal, ISSN: 15507416
Dana Baker; Gerry Nakamura; Henry Lowman; Sally Fischer
Journal of Biological Chemistry, ISSN: 1083351X
Daniela Yadav; Vikas Sharma; Andy Boswell; Isidro Hotzel; Devin Tesar; Yonglei Shang; Yong Ying; Sally Fischer; Jane Grogan; Eugene Chiang; Konnie Urban; Sheila Ulufatu; Leslie Khawli; Saileta Prabhu; Sean Joseph; Robert F. Kelley
Thorax, ISSN: 14683296
Nicola A. Hanania; Michael Noonan; Jonathan Corren; Phillip Korenblat; Yanan Zheng; Sally Fischer; Melissa Cheu; Wendy Putnam; Elaine Murray; Heleen Scheerens; Cecile Holweg; Romeo Maciuca; Sarah Gray; Ramona Doyle; Mcclintock; Julie Olsson; John Matthews; Karl Yen
AAPS Journal, ISSN: 15507416
Sally Fischer; Alison Joyce; Mark Spengler; Tong-Yuan Yang; Yao Zhuang; Marianne Scheel Fjording; Alvydas Mikulskis
Bioanalysis, ISSN: 17576199
Julia Qiu; Yong Ying He; Sock-Cheng Lewin-Koh; Daniel Coleman; Sue Brignoli; Robert Hendricks; Patty Siguenza; Valerie Quarmby; Sally Fischer; An Song
mAbs, ISSN: 19420870
Kate Peng; Keyang Xu; Luna Liu; Robert Hendricks; Reginald Delarosa; Rich Erickson; Nageshwar Budha; Maya Leabman; An Song; Surinder Kaur; Sally Fischer
Arthritis Research and Therapy, ISSN: 14786362
Glynn Dennis Jr; Cecile Holweg; Sarah Kummerfeld; David Choy; Francesca Setiadi; Jason Hackney; Pete Haverty; Houston Gilbert; Wei Lin; Lauri Diehl; Sally Fischer; An Song; David Musselman; Micki Klearman; Cem Gabay; Arthur Kavanaugh; Judith Endres; David A. Fox; Flavius Martin; Michael Townsend
Current Medical Research and Opinion, ISSN: 14734877
Dana Baker; Kate Peng; Melissa Cheu; Sally Fischer
Current Medical Research and Opinion, ISSN: 14734877
Dana Baker; Kate Peng; Melissa Cheu; Sally Fischer
AAPS Journal, ISSN: 15507416
Kate Peng; Dana Baker; Sue Brignoli; Janis Cabuhat; Sally Fischer
Bioanalysis, ISSN: 17576180
Kyra Cowan; Rich Erickson; Brian Sue; Reginald Delarosa; Bert Gunter; Daniel Coleman; Houston Gilbert; An Song; Sally Fischer
mAbs, ISSN: 19420862
Sally Fischer; Jihong Yang; Banmeet Anand; Kyra Cowan; Robert Hendricks; Jing Li; Gerry Nakamura; An Song
AAPS Journal, ISSN: 15507416
Frank P. Spriggs; Zhandong Don Zhong; Afshin Safavi; Darshana Jani; Narasaiah Dontha; Anita Kant; Jenny Ly; Lia Brilando; Karolina Österlund; Nathalie Rouleau; Sally Fischer; Martin Boissonneault; Chad Ray
Journal of Pharmaceutical and Biomedical Analysis, ISSN: 07317085
James Araujo; Marcel Zocher; Kristin Wallace; Kate Peng; Sally Fischer
Journal of Pharmaceutical and Biomedical Analysis, ISSN: 07317085
Kate Peng; Ketevan Siradze; Valerie Quarmby; Sally Fischer
Clinical Pharmacology and Therapeutics, ISSN: 00099236
Yanan Zheng; Heleen Scheerens; John C. Davis; Rong Deng; Sally Fischer; Woods; Paul Fielder; Eric Stefanich
Education
- University of South Carolina, Ph.D. in Biochemistry – 1992