Weiru Wang
Senior Principal Scientist (Technology), Structural Biology
Postdoc Mentor
16
Years at Genentech
66
Publications at Genentech
I started my lab at Genentech in June 2007. Being a scientist at Genentech is both exciting and challenging. I enjoy having the privilege of collaborating with many extremely talented colleagues. Together, we harness opportunities to discover basic science and to translate them into innovative medicine that we hope can make a difference in patients’ lives. My lab has interests in understanding the molecular basis of protein-drug interactions using biophysical methods, primarily macromolecular crystallography. At Genentech, our drug discovery efforts aim at tackling protein targets with “atomic precision”. My lab’s research provides structural insights into disease-related biological molecules, and enables structure-based design of small-molecule and antibody drugs.
Prior to Genentech, I was a senior scientist in Structural Biology at Plexxikon, a biotech start-up in Berkeley, CA, where I worked on drug discovery programs for cancer and metabolic disorder. Prior to Plexxikon, I was a staff scientist in the Physical Biosciences Division at Lawrence Berkeley National Laboratory, where I worked on structural genomics projects.
Featured Publication
Small-molecule ligands bind to a distinct pocket in RAS and inhibit nucleotide exchange activity.
(2012) Proc Natl Acad Sci USA, 109(14):5299-304
Maurer T, Garrenton LS, Oh A, Pitts K, Anderson DJ, Skelton NJ, Fauber BP, Pan B, Malek S, Stokoe D, Ludlam MJ, Bowman KK, Wu J, Giannetti AM, Starovasnik MA, Mellman I, Jackson PK, Rudolph J, Wang W, Fang G.
My Focus
My lab’s research activities are focused on the structure determination of drug targets, mostly in the field of oncology and neurodegeneration.
Co-crystallography is vital to structure-based drug design. We collaborate with Medicinal Chemistry and Antibody Engineering on multiple drug discovery projects.
On the basic research side, we have interests in gaining structural insights into biological molecules and molecular assemblies with therapeutic importance. We expect that such knowledge can provide the basis for developing future drug discovery strategy.
We also play a critical role in technology development. An important aspect of my lab’s activity is to improve and implement the high-throughput crystallography platform within the Structural Biology Department.
Genentech Publications
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 10916490 00278424
Siyu Feng; Marinella G. Callow; Jean-Philippe Fortin; Zia Khan; David Bray; Michael Costa; Shi; Weiru Wang; Marie Evangelista
Nature Biotechnology, ISSN: 15461696 10870156
Christopher W. Davies; Angela Oh; Rana Mroue; Micah Steffek; John M. Bruning; Yang Xiao; Siyu Feng; Sangeeta Jayakar; Emily Chan; Vidhyalakshmi Arumugam; Sean Carlo Uribe; Jake Drummond; Alexandra Frommlet; Cheng Lu; Yvonne Franke; Mark Merchant; Koeppen; John Quinn; Sushant Malhotra; Steven Do; Lewis Gazzard; Hans E. Purkey; Joachim Rudolph; Melinda M. Mulvihill; James T. Koerber; Weiru Wang; Marie Evangelista
ACS Medicinal Chemistry Letters, ISSN: 19485875
Bryan K. Chan; Eileen Seward; Michael Lainchbury; Thomas F. Brewer; Le An; Toby Blench; Matthew W. Cartwright; Grace Chan; Edna F. Choo; Jason H. Drummond; Richard Elliott; Emanuela Gancia; Lewis Gazzard; Baihua Hu; Graham Jones; Xifeng Luo; Andrew Madin; Sushant Malhotra; John Moffat; Jodie Pang; Laurent Salphati; Chris J. Sneeringer; Craig E. Stivala; Binqing Wei; Weiru Wang; Ping Wu; Timothy P. Heffron
Nature Biotechnology, ISSN: 15461696 10870156
Christopher W. Davies; Angela Oh; Rana Mroue; Micah Steffek; John M. Bruning; Yang Xiao; Siyu Feng; Sangeeta Jayakar; Emily Chan; Vidhyalakshmi Arumugam; Sean Carlo Uribe; Jake Drummond; Alexandra Frommlet; Cheng Lu; Yvonne Franke; Mark Merchant; Koeppen; John Quinn; Sushant Malhotra; Steven Do; Lewis Gazzard; Hans E. Purkey; Joachim Rudolph; Melinda M. Mulvihill; James T. Koerber; Weiru Wang; Marie Evangelista
Nature Communications, ISSN: 20411723
Adrien Le Thomas; Elena Ferri; Scot A. Marsters; Jonathan M. Harnoss; David Lawrence; Iratxe Zuazo-Gaztelu; Zora Modrusan; Sara M. Chan; Margaret Solon; Cecile Chalouni; Weihan Li; Koeppen; Joachim Rudolph; Weiru Wang; Thomas D Wu; Peter Walter; Avi Ashkenazi
Nature Communications, ISSN: 20411723
Adrien Le Thomas; Elena Ferri; Scot A. Marsters; Jonathan M. Harnoss; David Lawrence; Iratxe Zuazo-Gaztelu; Zora Modrusan; Sara Chan; Margaret Solon; Cecile Chalouni; Weihan Li; Koeppen; Joachim Rudolph; Weiru Wang; Thomas D Wu; Peter Walter; Avi Ashkenazi
ACS Medicinal Chemistry Letters, ISSN: 19485875
Malcolm P. Huestis; Matthew Durk; Eigenbrot; Paul Gibbons; Thomas Hunsaker; Hank La; Dennis H. Leung; Wendy Liu; Shiva Malek; Mark Merchant; John Moffat; Christine S. Muli; Christine Orr; Brendan T. Parr; Frances Shanahan; Chris J. Sneeringer; Weiru Wang; Ivana Yen; Jianping Yin; Joachim Rudolph; Michael Siu
Journal of Medicinal Chemistry, ISSN: 15204804 00222623
Malcolm P. Huestis; Darlene Dela Cruz; Antonio G. DiPasquale; Matthew Durk; Eigenbrot; Paul Gibbons; Alberto Gobbi; Thomas Hunsaker; Hank La; Dennis H. Leung; Wendy Liu; Shiva Malek; Mark Merchant; John Moffat; Christine S. Muli; Christine Orr; Brendan T. Parr; Frances Shanahan; Chris J. Sneeringer; Weiru Wang; Ivana Yen; Jianping Yin; Michael Siu; Joachim Rudolph
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Xuan Gao; Weiru Wang; Devin B. Tesar; Bingchuan Wei; John Eschelbach; Robert F. Kelley; Guoying Jiang
ACS Medicinal Chemistry Letters, ISSN: 19485875
Ramsay E. Beveridge; Heidi J. A. Wallweber; Avi Ashkenazi; Beresini; Clark; Paul Gibbons; Elise Ghiro; Susan Kaufman; Alexandre Larivée; Melissa Leblanc; Jean-Philippe Leclerc; Alexandre Lemire; Cuong Ly; Joachim Rudolph; Jacob B. Schwarz; Sanjay Srivastava; Weiru Wang; Zhao; Marie-Gabrielle Braun
ACS Medicinal Chemistry Letters, ISSN: 19485875
Ramsay E. Beveridge; Heidi J. A. Wallweber; Avi Ashkenazi; Beresini; Clark; Paul Gibbons; Elise Ghiro; Susan Kaufman; Alexandre Larivée; Melissa Leblanc; Jean-Philippe Leclerc; Alexandre Lemire; Cuong Ly; Joachim Rudolph; Jacob B. Schwarz; Sanjay Srivastava; Weiru Wang; Liang Zhao; Marie-Gabrielle Braun
Nature Communications, ISSN: 20411723
Elena Ferri; Adrien Le Thomas; Heidi J. A. Wallweber; Eric S. Day; Benjamin T. Walters; Susan Kaufman; Marie-Gabrielle Braun; Clark; Beresini; Kyle Mortara; Yung-Chia Ariel Chen; Breanna Canter; Wilson Phung; Peter S. Liu; Alfred Lammens; Avi Ashkenazi; Joachim Rudolph; Weiru Wang
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 10916490 00278424
Jonathan M. Harnoss; Adrien Le Thomas; Anna Shemorry; Scot A. Marsters; David Lawrence; Min Lu; Yung-Chia Ariel Chen; Jing Qing; Klara Totpal; David Kan; Ehud Segal; Mark Merchant; Mike Reichelt; Heidi J. A. Wallweber; Weiru Wang; Clark; Susan Kaufman; Beresini; Steven T. Laing; Wendy N. Sandoval; Maria N. Lorenzo; Jiansheng Wu; Justin Ly; Tom De Bruyn; Amy Heidersbach; Benjamin Haley; Alvin Gogineni; Robby M. Weimer; Dong Lee; Marie-Gabrielle Braun; Joachim Rudolph; Michael J. VanWyngarden; Daniel W. Sherbenou; Patricia Gomez-Bougie; Amiot; Diego Acosta-Alvear; Peter Walter; Avi Ashkenazi
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 10916490 00278424
Laurel M. Pegram; Jennifer C. Liddle; Yao Xiao; Maria Hoh; Johannes Rudolph; Dylan B. Iverson; Guy Vigers; Darin Smith; Hailong Zhang; Weiru Wang; John Moffat; Natalie G. Ahn
mAbs, ISSN: 19420870 19420862
Ayse Meric Ovacik; Ji Li; Marie Lemper; Dimitry Danilenko; Nicola J. Stagg; Mary Mathieu; Diego Ellerman; Vinita Gupta; Navdeep Kalia; Trung Nguy; Vicki Plaks; Clarissa David Johnson; Weiru Wang; Jochen Brumm; Bernard M. Fine; Teemu T. Junttila; Kedan Lin; Paul J. Carter; Saileta Prabhu; Christoph Spiess; Amrita Kamath
Bioconjugate Chemistry, ISSN: 15204812 10431802
Nicholas Vance; Neelie Zacharias; Ultsch; Guangmin Li; Aimee Fourie; Peter S. Liu; Julien Lafrance-Vanasse; James A. Ernst; Wendy N. Sandoval; Katherine R. Kozak; Gail L. Phillips; Weiru Wang; Jack D. Sadowsky
Structure, ISSN: 18784186 09692126
Ping Wu; Chris J. Sneeringer; Keith Pitts; Eric S. Day; Bryan K. Chan; Binqing Wei; Isabelle Lehoux; Kyle Mortara; Hong Li; Jiansheng Wu; Yvonne Franke; John Moffat; Jane L. Grogan; Timothy P. Heffron; Weiru Wang
Nature Chemical Biology, ISSN: 15524469 15524450
Aaron H Nile; Felipe de Sousa e Melo; Susmith Mukund; Robert Piskol; Simon Hansen; Lijuan Zhou; Yingnan Zhang; Yue Fu; Emily Gogol; László Kömüves; Zora Modrusan; Stephane Angers; Yvonne Franke; Christopher M. Koth; Wayne J. Fairbrother; Weiru Wang; Frederic J. De Sauvage; Rami N. Hannoush
Clinical Cancer Research, ISSN: 15573265 10780432
Bijay S. Jaiswal; Durinck; Eric Stawiski; Jianping Yin; Weiru Wang; Eva Lin; John Moffat; Scott E. Martin; Zora Modrusan; Somasekar Seshagiri
Nature Chemical Biology, ISSN: 15524469 15524450
Aaron H Nile; Felipe de Sousa e Melo; Susmith Mukund; Robert Piskol; Simon Hansen; Lijuan Zhou; Yingnan Zhang; Yue Fu; Emily Gogol; László Kömüves; Zora Modrusan; Stephane Angers; Yvonne Franke; Christopher M. Koth; Wayne J. Fairbrother; Weiru Wang; Frederic J. De Sauvage; Rami N. Hannoush
OMICS A Journal of Integrative Biology, ISSN: 15578100 15362310
Babylakshmi Muthusamy; Lakshmi Dhevi N. Selvan; Thong T Nguyen; Jesna Manoj; Eric Stawiski; Bijay S. Jaiswal; Weiru Wang; Remya Raja; Vedam Laxmi Ramprasad; Ravi Gupta; Sakthivel Murugan; Jayarama S. Kadandale; Keshava Prasad; Kavita Reddy; Andrew S. Peterson; Akhilesh Pandey; Somasekar Seshagiri; Satish Chandra Girimaji; Harsha Gowda
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 10916490 00278424
Aaron H Nile; Susmith Mukund; Karen Stanger; Weiru Wang; Rami N. Hannoush
Scientific Reports, ISSN: 20452322
Ultsch; Bing Li; Till Maurer; Mary Mathieu; Oskar Adolfsson; Andreas Muhs; Andrea Pfeifer; Maria Pihlgren; Travis W. Bainbridge; Mike Reichelt; James A. Ernst; Eigenbrot; Fuh; Jasvinder K. Atwal; Ryan J. Watts; Weiru Wang
Journal of Medicinal Chemistry, ISSN: 15204804 00222623
Mark Zak; Po-Wai Yuen; Xiongcai Liu; Snahel Patel; Deepak Sampath; Jason Oeh; Bianca M. Liederer; Weiru Wang; Thomas O'Brien; Yang Xiao; Nicholas J. Skelton; Rongbao Hua; Jasleen K. Sodhi; Yunli Wang; Lei Zhang; Guiling Zhao; Xiaozhang Zheng; Yen-Ching Ho; Kenneth W. Bair; Peter Dragovich
Journal of Medicinal Chemistry, ISSN: 15204804 00222623
James F. Blake; Michael Burkard; Jocelyn Chan; Huifen Chen; Kang-Jye Chou; Dolores Diaz; Danette Dudley; John J. Gaudino; Stephen Gould; Jonas Grina; Thomas Hunsaker; Lichuan Liu; Matthew Martinson; David Moreno; Lars Mueller; Christine Orr; Patricia Pacheco; Ann R. Qin; Kevin Rasor; Li Ren; Kirk D. Robarge; Sheerin Shahidi-Latham; Jeffrey Stults; Francis Sullivan; Weiru Wang; Jianping Yin; Aihe Zhou; Marcia Belvin; Mark Merchant; John Moffat; Jacob B. Schwarz
Journal of Medicinal Chemistry, ISSN: 15204804 00222623
Joachim Rudolph; Lesley J. Murray; Chudi O. Ndubaku; Thomas O'Brien; Elizabeth M. Blackwood; Weiru Wang; Ignacio Aliagas; Lewis Gazzard; James J. Crawford; Joy Drobnick; Wendy Lee; Xianrui Zhao; Klaus P. Hoeflich; David A. Favor; Ping Dong; Haiming Zhang; Christopher E. Heise; Angela Oh; Christy C. Ong; Hank La; Paroma Chakravarty; Connie Chan; Diana Jakubiak; Jennifer A. Epler; Sreemathy Ramaswamy; Roxanne Vega; Cain; Dolores Diaz; Yu Zhong
Bioorganic and Medicinal Chemistry Letters, ISSN: 14643405 0960894X
Wendy Lee; James J. Crawford; Ignacio Aliagas; Lesley J. Murray; Suzanne Tay; Weiru Wang; Christopher E. Heise; Klaus P. Hoeflich; Hank La; Simon Mathieu; Robert Mintzer; Sreemathy Ramaswamy; Lionel Rouge; Joachim Rudolph
ACS Medicinal Chemistry Letters, ISSN: 19485875
Chudi O. Ndubaku; James J. Crawford; Joy Drobnick; Ignacio Aliagas; David Campbell; Ping Dong; Laura M. Dornan; Sergio G. Duron; Jennifer A. Epler; Lewis Gazzard; Christopher E. Heise; Klaus P. Hoeflich; Diana Jakubiak; Hank La; Wendy Lee; Baiwei Lin; Joseph P. Lyssikatos; Jasna Maksimoska; Ronen Marmorstein; Lesley J. Murray; Thomas O'Brien; Angela Oh; Sreemathy Ramaswamy; Weiru Wang; Xianrui Zhao; Yu Zhong; Elizabeth M. Blackwood; Joachim Rudolph
Bioorganic and Medicinal Chemistry Letters, ISSN: 14643405 0960894X
Burdick; Shumei Wang; Christopher E. Heise; Borlan Pan; Jake Drummond; Jianping Yin; Lauren Goeser; Steven Magnuson; Jeff Blaney; John Moffat; Weiru Wang; Huifen Chen
Journal of Medicinal Chemistry, ISSN: 15204804 00222623
James J. Crawford; Wendy Lee; Ignacio Aliagas; Simon Mathieu; Klaus P. Hoeflich; Wei Zhou; Weiru Wang; Lionel Rouge; Lesley J. Murray; Hank La; Ning Liu; Peter W. Fan; Jonathan Cheong; Christopher E. Heise; Sreemathy Ramaswamy; Robert Mintzer; Yanzhou Liu; Qi Chao; Joachim Rudolph
ACS Medicinal Chemistry Letters, ISSN: 19485875
Joachim Rudolph; Ignacio Aliagas; James J. Crawford; Simon Mathieu; Wendy Lee; Qi Chao; Ping Dong; Lionel Rouge; Weiru Wang; Christopher E. Heise; Lesley J. Murray; Hank La; Yanzhou Liu; Gerard Manning; François Diederich; Klaus P. Hoeflich
Nature Chemical Biology, ISSN: 15524469 15524450
Hayley J. Sharpe; Weiru Wang; Rami N. Hannoush; Frederic J. De Sauvage
Journal of Medicinal Chemistry, ISSN: 15204804 00222623
Li Ren; Jonas Grina; David Moreno; James F. Blake; John J. Gaudino; Rustam Garrey; Andrew T. Metcalf; Michael Burkard; Matthew Martinson; Kevin Rasor; Huifen Chen; Brian J. Dean; Stephen Gould; Patricia Pacheco; Sheerin Shahidi-Latham; Jianping Yin; Kristina West; Weiru Wang; John Moffat; Jacob B. Schwarz
Bioorganic and Medicinal Chemistry Letters, ISSN: 14643405 0960894X
Mark Zak; Bianca M. Liederer; Deepak Sampath; Po-Wai Yuen; Kenneth W. Bair; Timm Baumeister; Alexandre J. Buckmelter; Karl H. Clodfelter; Eric Cheng; Lisa Crocker; Bang Fu; Bingsong Han; Guangkun Li; Yen-Ching Ho; Jian Lin; Xiongcai Liu; Justin Ly; Thomas O'Brien; Dominic J. Reynolds; Nicholas J. Skelton; Chase C. Smith; Suzanne Tay; Weiru Wang; Zhongguo Wang; Yang Xiao; Lei Zhang; Guiling Zhao; Xiaozhang Zheng; Peter Dragovich
Journal of Medicinal Chemistry, ISSN: 15204804 00222623
Joachim Rudolph; James J. Crawford; Klaus P. Hoeflich; Weiru Wang
Nature Genetics, ISSN: 15461718 10614036
Durinck; Eric W. Stawiski; Andrea Pavía-Jiménez; Zora Modrusan; Payal Kapur; Bijay S. Jaiswal; Na Zhang; Vanina Toffessi-Tcheuyap; Thong T Nguyen; Kanika Bajaj Pahuja; Ying-Jiun Chen; Sadia Saleem; Subhra Chaudhuri; Sherry Heldens; Marlena Jackson; Samuel Peña-Llopis; Joseph Guillory; Toy; Connie Ha; Corissa J Harris; Eboni Holloman; Haley M Hill; Stinson; Rivers; Vasantharajan Janakiraman; Weiru Wang; Lisa N Kinch; Nick V Grishin; Peter M. Haverty; Bernard Chow; Julian S Gehring; Jens Reeder; Gregoire Pau; Thomas D Wu; Vitaly Margulis; Yair Lotan; Arthur Sagalowsky; Ivan Pedrosa; Frederic J. De Sauvage; James Brugarolas; Somasekar Seshagiri
Nature Genetics, ISSN: 15461718 10614036
Durinck; Eric Stawiski; Andrea Pavía-Jiménez; Zora Modrusan; Payal Kapur; Bijay S. Jaiswal; Na Zhang; Vanina Toffessi-Tcheuyap; Thong T Nguyen; Kanika Bajaj Pahuja; Ying-Jiun J. Chen; Sadia Saleem; Subhra Chaudhuri; Sherry Heldens; Marlena Jackson; Samuel Peña-Llopis; Joseph Guillory; Toy; Connie Ha; Corissa J. Harris; Eboni Holloman; Haley M Hill; Stinson; Rivers; Vasantharajan Janakiraman; Weiru Wang; Lisa N. Kinch; Nick V Grishin; Matthias Peter; Bernard Chow; Julian S. Gehring; Jens Reeder; Gregoire Pau; Thomas D Wu; Vitaly Margulis; Yair Lotan; Arthur Sagalowsky; Ivan Pedrosa; Frederic J. De Sauvage; James Brugarolas; Somasekar Seshagiri
PLoS ONE, ISSN: 19326203
Weiru Wang; Kristi Elkins; Angela Oh; Yen-Ching Ho; Jiansheng Wu; Hong Li; Yang Xiao; Mandy Kwong; Mary Coons; Bobby Brillantes; Eric Cheng; Lisa Crocker; Peter Dragovich; Deepak Sampath; Xiaozhang Zheng; Kenneth W. Bair; Thomas O'Brien; Lisa D. Belmont
Bioorganic and Medicinal Chemistry Letters, ISSN: 14643405 0960894X
Benjamin P. Fauber; Olivier René; Gladys De Leon Boenig; Brenda Burton; Yuzhong Deng; Celine Eidenschenk; Christine Everett; Alberto Gobbi; Sarah G. Hymowitz; Adam R. Johnson; Hank La; Marya Liimatta; Peter Lockey; Maxine Norman; Wenjun Ouyang; Weiru Wang; Harvey Wong
Science Signaling, ISSN: 19379145 19450877
Juliane Mooz; Tripat Kaur Oberoi-Khanuja; Gregory S. Harms; Weiru Wang; Bijay S. Jaiswal; Somasekar Seshagiri; Ritva Tikkanen; Krishnaraj Rajalingam
Bioorganic and Medicinal Chemistry Letters, ISSN: 14643405 0960894X
James F. Blake; John J. Gaudino; Jason De Meese; Peter Mohr; Mark Chicarelli; Hongqi Tian; Rustam Garrey; Allen A. Thomas; Christopher S. Siedem; Michael Welch; Gabrielle Kolakowski; Robert Kaus; Michael Burkard; Matthew Martinson; Huifen Chen; Brian J. Dean; Danette Dudley; Stephen Gould; Patricia Pacheco; Sheerin Shahidi-Latham; Weiru Wang; Kristina West; Jianping Yin; John Moffat; Jacob B. Schwarz
ChemBioChem, ISSN: 14397633 14394227
Angela Oh; Yen-Ching Ho; Mark Zak; Yongbo Liu; Xukun Chen; Po-Wai Yuen; Xiaozhang Zheng; Yichin Liu; Peter Dragovich; Weiru Wang
Analytical Chemistry, ISSN: 15206882 00032700
Yi Yang; Cinzia Stella; Weiru Wang; Christian Schöneich; Lynn Gennaro
Clinical Cancer Research, ISSN: 15573265 10780432
Richard Bourgon; Shan Lu; Yibing Yan; Lackner; Weiru Wang; Victor Weigman; David Wang; Yinghui Guan; Lisa Ryner; Koeppen; Rajesh Patel; Garret M. Hampton; Lukas Amler; Wang
Journal of Medicinal Chemistry, ISSN: 00222623 15204804
Anthony M. Giannetti; Xiaozhang Zheng; Nicholas J. Skelton; Weiru Wang; Brandon Bravo; Kenneth W. Bair; Timm Baumeister; Eric Cheng; Lisa Crocker; Yezhen Feng; Janet Gunzner; Yen-Ching Ho; Rongbao Hua; Bianca M. Liederer; Yongbo Liu; Xiaolei Ma; Thomas O'Brien; Jason Oeh; Deepak Sampath; Youming Shen; Chengcheng Wang; Leslie Wang; Hongxing Wu; Yang Xiao; Po-Wai Yuen; Mark Zak; Guiling Zhao; Qiang Zhao; Peter Dragovich
Journal of Medicinal Chemistry, ISSN: 00222623 15204804
Steven T. Staben; Jianwen A. Feng; Karen Lyle; Marcia Belvin; Jason Boggs; Jason D. Burch; Ching-Ching Chua; Haifeng Cui; Antonio G. DiPasquale; Lori S. Friedman; Christopher E. Heise; Koeppen; Adrian Kotey; Robert Mintzer; Angela Oh; David Allen Roberts; Lionel Rouge; Joachim Rudolph; Christine Tam; Weiru Wang; Yisong Xiao; Amy Young; Yamin Zhang; Klaus P. Hoeflich
Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X 14643405
Peter Dragovich; Guiling Zhao; Timm Baumeister; Brandon Bravo; Anthony M. Giannetti; Yen-Ching Ho; Rongbao Hua; Guangkun Li; Xiaorong Liang; Xiaolei Ma; Thomas O'Brien; Angela Oh; Nicholas J. Skelton; Chengcheng Wang; Weiru Wang; Yunli Wang; Yang Xiao; Po-Wai Yuen; Mark Zak; Qiang Zhao; Xiaozhang Zheng
Annual Review of Pharmacology and Toxicology, ISSN: 15454304 03621642
Lingyan Jin; Weiru Wang; Guowei Fang
Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X 14643405
Xiaozhang Zheng; Timm Baumeister; Alexandre J. Buckmelter; Maureen Caligiuri; Karl H. Clodfelter; Bingsong Han; Yen-Ching Ho; Nikolai Kley; Jian Lin; Dominic J. Reynolds; Geeta Sharma; Chase C. Smith; Zhongguo Wang; Peter Dragovich; Angela Oh; Weiru Wang; Mark Zak; Yunli Wang; Po-Wai Yuen; Kenneth W. Bair
Current Opinion in Structural Biology, ISSN: 0959440X 1879033X
Weiru Wang; Yichin Liu; Lazarus
Tetrahedron Letters, ISSN: 00404039 18733581
Malcolm P. Huestis; Wendy Liu; Matthew Volgraf; Hans E. Purkey; Christine Yu; Weiru Wang; Darin Smith; Guy Vigers; Darrin Dutcher; Kevin W. Hunt; Michael Siu
Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X 14643405
Xiaozhang Zheng; Kenneth W. Bair; Paul Bauer; Timm Baumeister; Krista K. Bowman; Alexandre J. Buckmelter; Maureen Caligiuri; Karl H. Clodfelter; Yezhen Feng; Bingsong Han; Yen-Ching Ho; Nikolai Kley; Hong Li; Xiaorong Liang; Bianca M. Liederer; Jian Lin; Justin Ly; Thomas O'Brien; Jason Oeh; Angela Oh; Dominic J. Reynolds; Deepak Sampath; Geeta Sharma; Nicholas J. Skelton; Chase C. Smith; Jarrod Tremayne; Leslie Wang; Weiru Wang; Zhongguo Wang; Hongxing Wu; Jiansheng Wu; Yang Xiao; Guangxing Yang; Po-Wai Yuen; Mark Zak; Peter Dragovich
Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X 14643405
Peter Dragovich; Kenneth W. Bair; Timm Baumeister; Yen-Ching Ho; Bianca M. Liederer; Xiongcai Liu; Yongbo Liu; Thomas O'Brien; Jason Oeh; Deepak Sampath; Nicholas J. Skelton; Leslie Wang; Weiru Wang; Hongxing Wu; Yang Xiao; Po-Wai Yuen; Mark Zak; Lei Zhang; Xiaozhang Zheng
Journal of Medicinal Chemistry, ISSN: 00222623 15204804
Xiaozhang Zheng; Paul Bauer; Timm Baumeister; Alexandre J. Buckmelter; Maureen Caligiuri; Karl H. Clodfelter; Bingsong Han; Yen-Ching Ho; Nikolai Kley; Jian Lin; Dominic J. Reynolds; Geeta Sharma; Chase C. Smith; Zhongguo Wang; Peter Dragovich; Janet Gunzner; Bianca M. Liederer; Justin Ly; Thomas O'Brien; Angela Oh; Leslie Wang; Weiru Wang; Yang Xiao; Mark Zak; Guiling Zhao; Po-Wai Yuen; Kenneth W. Bair
Clinical Cancer Research, ISSN: 10780432 15573265
Cuiling Zhong; Jianyong Wang; Bing Li; Hong Xiang; Ultsch; Mary Coons; Wong; Nancy Y. Chiang; Suzanna Clark; Robyn Clark; Leah Quintana; Gribling; Eric Suto; Kai H. Barck; Corpuz; Jenny Yao; Rashi Takkar; Wyne P. Lee; Lisa A. Damico; Richard A. D. Carano; Adams; Robert F. Kelley; Weiru Wang; Napoleone Ferrara
Journal of Medicinal Chemistry, ISSN: 00222623 15204804
Xiaozhang Zheng; Paul Bauer; Timm Baumeister; Alexandre J. Buckmelter; Maureen Caligiuri; Karl H. Clodfelter; Bingsong Han; Yen-Ching Ho; Nikolai Kley; Jian Lin; Dominic J. Reynolds; Geeta Sharma; Chase C. Smith; Zhongguo Wang; Peter Dragovich; Angela Oh; Weiru Wang; Mark Zak; Janet Gunzner; Guiling Zhao; Po-Wai Yuen; Kenneth W. Bair
Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X 14643405
Janet Gunzner; Guiling Zhao; Paul Bauer; Timm Baumeister; Alexandre J. Buckmelter; Maureen Caligiuri; Karl H. Clodfelter; Bang Fu; Bingsong Han; Yen-Ching Ho; Nikolai Kley; Xiaorong Liang; Bianca M. Liederer; Jian Lin; Sophie Mukadam; Thomas O'Brien; Angela Oh; Dominic J. Reynolds; Geeta Sharma; Nicholas J. Skelton; Chase C. Smith; Jasleen K. Sodhi; Weiru Wang; Zhongguo Wang; Yang Xiao; Po-Wai Yuen; Mark Zak; Lei Zhang; Xiaozhang Zheng; Kenneth W. Bair; Peter Dragovich
Enzymes, ISSN: 18746047
Till Maurer; Weiru Wang
Bioorganic and Medicinal Chemistry Letters, ISSN: 14643405 0960894X
Weiru Wang; Guowei Fang; Joachim Rudolph
Nature, ISSN: 00280836 14764687
Somasekar Seshagiri; Eric Stawiski; Durinck; Zora Modrusan; Elaine E. Storm; Caitlin B. Conboy; Subhra Chaudhuri; Yinghui Guan; Vasantharajan Janakiraman; Bijay S. Jaiswal; Joseph Guillory; Connie Ha; Gerrit J. P. Dijkgraaf; Stinson; Florian Gnad; Melanie A. Huntley; Jeremiah D. Degenhardt; Matthias Peter; Richard Bourgon; Weiru Wang; Koeppen; Robert Gentleman; Timothy Starr; Zemin Zhang; David A. Largaespada; Thomas D Wu; Frederic J. De Sauvage
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424 10916490
Till Maurer; Lindsay S. Garrenton; Angela Oh; Keith Pitts; Daniel J Anderson; Nicholas J. Skelton; Benjamin P. Fauber; Borlan Pan; Shiva Malek; David Stokoe; Mary J. C. Ludlam; Krista K. Bowman; Jiansheng Wu; Anthony M. Giannetti; Melissa A. Starovasnik; Ira Mellman; Peter K Jackson; Joachim Rudolph; Weiru Wang; Guowei Fang
Genes and Development, ISSN: 08909369 15495477
Kevin J. Wright; Lisa M. Baye; Anique Olivier-Mason; Saikat Mukhopadhyay; Liyun Sang; Mandy Kwong; Weiru Wang; Pamela R. Pretorius; Val C. Sheffield; Piali Sengupta; Diane C. Slusarski; Peter K Jackson
Structure, ISSN: 09692126 18784186
Eric Bourhis; Weiru Wang; Christine Tam; Jiyoung Hwang; Yingnan Zhang; Didier Spittler; Oscar W Huang; Yan Gong; Alberto Estevez; Inna Zilberleyb; Lionel Rouge; Cecilia Chiu; Yan Wu; Michael Costa; Rami N. Hannoush; Yvonne Franke; Andrea G Cochran
Science Translational Medicine, ISSN: 19466234 19466242
Jasvinder K. Atwal; Yongmei Chen; Cecilia Chiu; Deborah L. Mortensen; William J. Meilandt; Yichin Liu; Christopher E. Heise; Kwame Hoyte; Wilman Luk; Yanmei Lu; Kun Peng; Ping Wu; Lionel Rouge; Yingnan Zhang; Lazarus; Kimberly Scearce-Levie; Weiru Wang; Yan Wu; Marc Tessier-Lavigne; Ryan J. Watts
Nature, ISSN: 00280836 14764687
Zhengyan Kan; Bijay S. Jaiswal; Stinson; Vasantharajan Janakiraman; Deepali Bhatt; Howard M. Stern; Peng Yue; Matthias Peter; Richard Bourgon; Jianbiao Zheng; Martin Moorhead; Subhra Chaudhuri; Lynn P. Tomsho; Brock A. Peters; Kanan Pujara; Shaun Cordes; David P. Davis; Victoria E. H. Carlton; Yuan; Li Li; Weiru Wang; Eigenbrot; Joshua S. Kaminker; Eberhard; Waring; Stephan C. Schuster; Zora Modrusan; Zemin Zhang; David Stokoe; Frederic J. De Sauvage; Malek Faham; Somasekar Seshagiri
Cancer Cell, ISSN: 15356108
Bijay S. Jaiswal; Vasantharajan Janakiraman; Noelyn Kljavin; Subhra Chaudhuri; Howard M. Stern; Weiru Wang; Zhengyan Kan; Hashem A. Dbouk; Brock A. Peters; Waring; Trisha Dela Vega; Denise M. Kenski; Krista K. Bowman; Maria N. Lorenzo; Hong Li; Jiansheng Wu; Zora Modrusan; Stinson; Mike Eby; Peng Yue; Joshua S. Kaminker; Frederic J. De Sauvage; Jonathan M. Backer; Somasekar Seshagiri
Education
- Cornell University, Ph.D. in Biophysics – 1999