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Publications

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DISPLAYING 5001 - 5050 OF 15583 RESULTS

A real-world study of patterns of Bacillus Calmette-Guerin (BCG) use and associated adverse events (AEs) in non-muscle invasive bladder cancer (NMIBC) patients in the United States
Annals of Oncology, ISSN: 15698041 09237534
Kathleen Wilson; Elisabetta Malangone-Monaco; Sacha Satram-Hoang; Diakun; Lin; Darren Tayama; Sarika Ogale
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PTEN loss as a predictive biomarker for the Akt inhibitor ipatasertib combined with abiraterone acetate in patients with metastatic castration-resistant prostate cancer (mCRPC)
Annals of Oncology, ISSN: 15698041 09237534
De Bono; De Giorgi; Christophe Massard; Sergio Bracarda; Nava Rodrigues; Ivo Kocak; Albert Font; J. Arranz Arija; Shih; George Daniel Radavoi; Yu; Wai Y. Chan; Steven Gendreau; Zhang; Ruth Riisnaes; Matthew Wongchenko; Daniel Maslyar; Viorel Jinga
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Second-line metastatic urothelial carcinoma treatment and survival in real-world patients in the US
Annals of Oncology, ISSN: 15698041 09237534
Sumanta Kumar Pal; Matthew D. Galsky; Shih Wen Lin; Sarika Ogale; Marko Zivkovic; Simpson; Christina L. Derleth; Guru Sonpavde
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Atezolizumab (atezo) in platinum (plat)-treated locally advanced/metastatic urothelial carcinoma (mUC): Updated OS, safety and biomarkers from the Ph II IMvigor210 study
Annals of Oncology, ISSN: 15698041 09237534
Yohann Loriot; Jonathan E. Rosenberg; Thomas Powles; Andrea Necchi; Syed Hussain; Morales; Margitta M. Retz; Günter Niegisch; Ignacio Durán; Christine Théodore; Jose Luis Perez-Gracia; Grande Pulido; AnnChristine Thåström; Bradford Danner; Sanjeev Mariathasan; Oyewale Abidoye; Michiel S Van Der Heijden
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Randomized phase 3 study in low-grade lymphoma comparing maintenance anti-CD20 antibody with observation after induction therapy: A trial of the ECOG-ACRIN cancer research group (E1496)
Cancer, ISSN: 10970142 0008543X
Stefan K. Barta; Hailun Li; Hochster; Fangxin Hong; Edie Weller; Randy D. Gascoyne; Thomas M. Habermann; Leo I. Gordon; Natalia Colocci; Elizabeth M. Bengtson; Sandra J. Horning; Wojciech Jurczak
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Somatic mutation, copy number and transcriptomic profiles of primary and matched metastatic estrogen receptor-positive breast cancers
Annals of Oncology, ISSN: 15698041 09237534
Fumagalli; Wilson; Roberto Salgado; Xuyang Lu; Yu; Carol O'Brien; Kimberly Walter; Huw; Carmen Criscitiello; Laios; Jose; Brown; Rothé; Maetens; Zardavas; Peter Savas; Denis Larsimont; Martine Piccart; Stefan Michiels; Lackner; Christos Sotiriou; Sherene Loi
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Comparison of lipid and lipid-associated cardiovascular risk marker changes after treatment with tocilizumab or adalimumab in patients with rheumatoid arthritis
Annals of the Rheumatic Diseases, ISSN: 14682060 00034967
Cem Gabay; McInnes; Arthur Kavanaugh; Katie Tuckwell; Micki Klearman; Jennifer Pulley; Naveed Sattar
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Practical Analysis and Visualization Tools for Benefit-Risk Assessment in Drug Development: A Review of Recent FDA Advisory Committee Meeting Packages
Statistics in Biopharmaceutical Research, ISSN: 19466315
Shihua Wen; Weili He; Scott R. Evans; George Quartey; Jonathan D. Norton; Christy Chuang-Stein; Qi Jiang; Haijun Ma; Mondira Bhattacharya
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Selecting and Integrating Data Sources in Benefit–Risk Assessment: Considerations and Future Directions
Statistics in Biopharmaceutical Research, ISSN: 19466315
Rachael L. DiSantostefano; Jesse A. Berlin; Christy Chuang-Stein; George Quartey; Gary Eichenbaum; Bennett Levitan
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Considerations on Endpoint Selection, Weighting Determination, and Uncertainty Evaluation in the Benefit-Risk Assessment of Medical Product
Statistics in Biopharmaceutical Research, ISSN: 19466315
Haijun Ma; Qi Jiang; Christy Chuang-Stein; Scott R. Evans; Weili He; George Quartey; John Scott; Shihua Wen; Ramin Arani
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Ritonavir-boosted danoprevir plus peginterferon alfa-2a and ribavirin in Asian chronic hepatitis C patients with or without cirrhosis
Journal of Gastroenterology and Hepatology (Australia), ISSN: 14401746 08159319
Jia-Horng Kao; Shui-Yi Tung; Younjae Lee; Satawat Thongsawat; Tanwandee; I.-Shyan Sheen; Jinzi J. Wu; Hui Li; Barbara J. Brennan; Julian Zhou; Sophie Le Pogam; Nájera; James A. Thommes; George Hill
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Using the HistoPress embedding tool to process murine colon samples for histopathology
Journal of Histotechnology, ISSN: 20460236 01478885
Susan Haller; Victor Nunez; Charles Havnar; Noa Safra; Oded Foreman
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Randomized phase 3 study in low-grade lymphoma comparing maintenance anti-CD20 antibody with observation after induction therapy: A trial of the ECOG-ACRIN cancer research group (E1496)
Cancer, ISSN: 10970142 0008543X
Stefan K. Barta; Hailun Li; Hochster; Fangxin Hong; Edie Weller; Randy D. Gascoyne; Thomas M. Habermann; Leo I. Gordon; Natalia Colocci; Elizabeth M. Bengtson; Sandra J. Horning; Brad Kahl
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Quantitative Prediction of Drug-Drug Interactions Involving Inhibitory Metabolites in Drug Development: How Can Physiologically Based Pharmacokinetic Modeling Help?
CPT: Pharmacometrics and Systems Pharmacology, ISSN: 21638306
Ian E. Templeton; Yuan Chen; Jialin Mao; Jian Lin; Hongbin Yu; Peters; Shebley; Varma
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Corticosteroid-related adverse events in patients with giant cell arteritis: A claims-based analysis
Seminars in Arthritis and Rheumatism, ISSN: 1532866X 00490172
Michael S. Broder; Khaled Sarsour; Eunice Chang; Neil Collinson; Katie Tuckwell; Pavel Napalkov; Micki Klearman
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Peripheral blood gene expression predicts clinical benefit from anti–IL-13 in asthma
Journal of Allergy and Clinical Immunology, ISSN: 10976825 00916749
David F. Choy; Guiquan Jia; Abbas Alexander; Katrina B. Morshead; Nicholas Lewin-Koh; Rajiv Dua; Pauline Rivera; Priscilla Moonsamy; Marcel Fontecha; Aarthi Balasubramanyam; Chris Santini; Ekaterina Bassett; Jill M. Ray; Christopher R. Cabanski; Mary S. Bradley; Romeo MacIuca; Mosesova; Heleen Scheerens; Joseph R. Arron
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Regulation of interleukin-10 expression
Advances in Experimental Medicine and Biology, ISSN: 22148019 00652598
Sascha Rutz; Wenjun Ouyang
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Clinical endpoints for the study of geographic atrophy secondary to age-related macular degeneration
Retina, ISSN: 15392864 0275004X
Srinivas Sadda; Usha Chakravarthy; David G. Birch; Giovanni Staurenghi; Erin C. Henry; Christopher Brittain
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Metabolic response to NAD depletion across cell lines is highly variable
PLoS ONE, ISSN: 19326203
Yang Xiao; Mandy Kwong; Anneleen Daemen; Marcia Belvin; Xiaorong Liang; Georgia Hatzivassiliou; Thomas O'Brien
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Ranibizumab Treatment for Pigment Epithelial Detachment Secondary to Neovascular Age-Related Macular Degeneration: Post Hoc Analysis of the HARBOR Study
Ophthalmology, ISSN: 15494713 01616420
David Sarraf; Nikolas J.S. London; Rahul N. Khurana; Pravin U. Dugel; Shamika Gune; Lauren Hill; Lisa Tuomi
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Non-cytochrome P450-mediated bioactivation and its toxicological relevance
Drug Metabolism Reviews, ISSN: 10979883 03602532
Jinping Gan; Shuguang Ma; Donglu Zhang
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Isolating the Role of Bevacizumab in Elderly Patients with Previously Untreated Nonsquamous Non-Small Cell Lung Cancer
American Journal of Clinical Oncology: Cancer Clinical Trials, ISSN: 1537453X 02773732
Corey Langer; Mark A. Socinski; Jyoti D. Patel; Alan Sandler; Joan H. Schiller; Larry Leon; Sebastien J. Hazard; Suresh Ramalingam
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Efficacy and safety of lebrikizumab in patients with uncontrolled asthma (LAVOLTA I and LAVOLTA II): replicate, phase 3, randomised, double-blind, placebo-controlled trials
The Lancet Respiratory Medicine, ISSN: 22132619 22132600
Nicola A. Hanania; Phillip Korenblat; Kenneth R Chapman; Eric D Bateman; Petr Kopecky; Pierluigi Paggiaro; Akihito Yokoyama; Julie Olsson; Sarah Gray; Cécile T.J. Holweg; Mark D. Eisner; Charles Asare; Saloumeh Kadkhodayan Fischer; Kun Peng; Wendy Putnam; Matthews
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An automated high-throughput metabolic stability assay using an integrated high-resolution accurate mass method and automated data analysis software
Drug Metabolism and Disposition, ISSN: 1521009X 00909556
Pranav Shah; Edward Kerns; Dac-Trung Nguyen; R. Scott Obach; Amy Q. Wang; Alexey Zakharov; John C. McKew; Anton Simeonov; Cornelis E. Hop; Xin Xu
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Clinical development of new drug-radiotherapy combinations
Nature Reviews Clinical Oncology, ISSN: 17594782 17594774
Ricky A. Sharma; Ruth Plummer; Julie K. Stock; Tessa A. Greenhalgh; Ozlem Ataman; Stephen Kelly; Robert Clay; Richard A. Adams; Richard Baird; Lucinda Billingham; Sarah R. Brown; Sean Buckland; Helen Bulbeck; Anthony J. Chalmers; Glen Clack; Aaron N. Cranston; Lars Damstrup; Roberta Ferraldeschi; Martin D. Forster; Julian Golec; Russell M. Hagan; Emma Hall; Axel-R. Hanauske; Kevin J. Harrington; Tom Haswell; Maria A. Hawkins; Tim Illidge; Hazel Jones; Andrew S. Kennedy; Fiona Mcdonald; Thorsten Melcher; James P.B. O'Connor; John R. Pollard; Mark P. Saunders; David Sebag-Montefiore; Melanie Smitt; John Staffurth; Ian J. Stratford; Stephen R. Wedge
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Reference ranges for serum periostin in a population without asthma or chronic obstructive pulmonary disease
Clinical and Experimental Allergy, ISSN: 13652222 09547894
Caswell-Smith; Hosking; Cripps; Cécile T.J. Holweg; Matthews; Holliday; Maillot; James Fingleton; Mark Weatherall; Irene Braithwaite; Beasley; Thomas Charles; Leonie Eastlake; Denise Fabian; Tony Mallon; Claire Munro; Janine Pilcher; Alison Pritchard; Michael Richards; Judith Riley; Philippa Shirtcliffe; Maureen Stretch; Mathew Williams; Jochen Brumm; Meghana Handigol; Julie Olsen; Karl Yen
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Carboxypeptidase D is the only enzyme responsible for antibody C-terminal lysine cleavage in Chinese hamster ovary (CHO) cells
Biotechnology and Bioengineering, ISSN: 10970290 00063592
Zhilan Hu; Henry Zhang; Benjamin Haley; Frank D. Macchi; Feng Yang; Shahram Misaghi; Joseph Elich; Renee Yang; Yun Tang; John C. Joly; Snedecor; Amy Shen
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1H, 13C and 15N backbone resonance assignment for the 40.5 kDa catalytic domain of Ubiquitin Specific Protease 7 (USP7)
Biomolecular NMR Assignments, ISSN: 1874270X 18742718
Paola Di Lello; Lionel Rouge; Borlan Pan; Till Maurer
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Metabolic plasticity underpins innate and acquired resistance to LDHA inhibition
Nature Chemical Biology, ISSN: 15524469 15524450
Aaron Boudreau; Hans E. Purkey; Anna Hitz; Kirk D. Robarge; David Peterson; Sharada Labadie; Mandy Kwong; Rebecca Hong; Min Gao; Christopher J. Del Nagro; Raju V. Pusapati; Shuguang Ma; Laurent Salphati; Jodie Pang; Aihe Zhou; Tommy Lai; Yingjie Li; Zhongguo Chen; Binqing Wei; Ivana Yen; Steve Sideris; Mark L. McCleland; Ron Firestein; Laura B. Corson; Alexander N. Vanderbilt; Simon P. Williams; Anneleen Daemen; Marcia Belvin; Eigenbrot; Peter K Jackson; Shiva Malek; Georgia Hatzivassiliou; Deepak Sampath; Marie Evangelista; Thomas O'Brien
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Antibody-drug conjugate characterization by chromatographic and electrophoretic techniques
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, ISSN: 1873376X 15700232
Tao Chen; Yan Chen; Cinzia Stella; Colin D. Medley; Jason Gruenhagen; Kelly Zhang
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Angioedema in the omalizumab chronic idiopathic/spontaneous urticaria pivotal studies
Annals of Allergy, Asthma and Immunology, ISSN: 15344436 10811206
James L. Zazzali; Allen P. Kaplan; Marcus Maurer; Karina Raimundo; Benjamin L. Trzaskoma; Paul G. Solari; Evgeniya Antonova; Meryl Mendelson; Karin Rosén
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A first-in-human phase I study to evaluate the MEK1/2 inhibitor, cobimetinib, administered daily in patients with advanced solid tumors
Investigational New Drugs, ISSN: 15730646 01676997
Lee Rosen; Patricia M. LoRusso; Wen Wee Ma; Jonathan W. Goldman; Amy Weise; A. Dimitrios Colevas; Alex Adjei; Salim Yazji; Angela Shen; Stuart H. Johnston; Hsin-Ju Hsieh; Iris Chan; Branimir I. Sikic
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Tocilizumab use in pregnancy: Analysis of a global safety database including data from clinical trials and post-marketing data
Seminars in Arthritis and Rheumatism, ISSN: 1532866X 00490172
Maria Hoeltzenbein; Evelin Beck; Richa Rajwanshi; Carina Gøtestam Skorpen; Erhan Berber; Christof Schaefer; Monika Østensen
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Investigation of low recovery in the free drug assay for antibody drug conjugates by size exclusion—reversed phase two dimensional-liquid chromatography
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, ISSN: 1873376X 15700232
Yi Li; Cinzia Stella; Laura Zheng; Charity Bechtel; Jason Gruenhagen; Fred Jacobson; Colin D. Medley
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Probing the Distribution of Water in a Multi-Component System by Solid-State NMR Spectroscopy
Pharmaceutical Research, ISSN: 1573904X 07248741
Pinal Mistry; Paroma Chakravarty; Joseph W. Lubach
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Development of a rapid RP-UHPLC–MS method for analysis of modifications in therapeutic monoclonal antibodies
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, ISSN: 1873376X 15700232
Bing Zhang; Justin Jeong; Braydon Burgess; Mansour Jazayri; Yun Tang; Taylor Zhang
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Characterization of therapeutic antibodies and related products by two-dimensional liquid chromatography coupled with UV absorbance and mass spectrometric detection
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, ISSN: 1873376X 15700232
Dwight R. Stoll; John Danforth; Kelly Zhang; Alain Beck
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Neoadjuvant Systemic Therapy for Breast Cancer: Factors Influencing Surgeons’ Referrals
Annals of Surgical Oncology, ISSN: 15344681 10689265
Eleftherios P. Mamounas; Christine Poulos; Hans-Peter Goertz; Juan Marcos González; Amy Pugh; Vincent Antao
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Developing HSCs become Notch independent by the end of maturation in the AGM region
Blood, ISSN: 15280020 00064971
Céline Souilhol; Javier G. Lendinez; Stanislav Rybtsov; Fiona Murphy; Heather Wilson; David Hills; Antoniana Batsivari; Anahí Binagui-Casas; Alison C. McGarvey; H. Robson MacDonald; Kageyama; Christian W. Siebel; Suling Zhao; Alexander Medvinsky
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Minimizing CYP2C9 Inhibition of Exposed-Pyridine NAMPT (Nicotinamide Phosphoribosyltransferase) Inhibitors
Journal of Medicinal Chemistry, ISSN: 15204804 00222623
Mark Zak; Po-Wai Yuen; Xiongcai Liu; Snahel Patel; Deepak Sampath; Jason Oeh; Bianca M. Liederer; Weiru Wang; Thomas O'Brien; Yang Xiao; Nicholas J. Skelton; Rongbao Hua; Jasleen K. Sodhi; Yunli Wang; Lei Zhang; Guiling Zhao; Xiaozhang Zheng; Yen-Ching Ho; Kenneth W. Bair; Peter Dragovich
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Interfering with the chronic immune response rescues chronic degeneration after traumatic brain injury
Journal of Neuroscience, ISSN: 15292401 02706474
Ali Ertürk; Susanne Mentz; Erik E. Stout; Maj Hedehus; Sara L. Dominguez; Lisa Neumaier; Franziska Krammer; Gemma Llovera; Karpagam Srinivasan; David V. Hansen; Arthur Liesz; Kimberly Scearce-Levie; Morgan Sheng
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Structural Characterization of Cross-Linked Species in Trastuzumab Emtansine (Kadcyla)
Bioconjugate Chemistry, ISSN: 15204812 10431802
Yan Chen; Michael Kim; Laura Zheng; Galahad Deperalta; Fred Jacobson
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Preparation of 2-Azabicyclo[21.1]hexane Hydrochloride
Synlett, ISSN: 14372096 09365214
Haili Liao; Aimin Li; Xingsong Chen; Kun Liang; Yang Shen; Qingfeng Liang; Kewei Xu; Daniel G. Shore; Elisia Villemure; Michael Siu; Malcolm P. Huestis
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Synthesis of Fused Imidazole-Containing Ring Systems via Dual Oxidative Amination of C(sp3)-H Bonds
Journal of Organic Chemistry, ISSN: 15206904 00223263
Georgette M. Castanedo; Yanzhou Liu; James J. Crawford; Marie-Gabrielle Braun
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A phase i dose-escalation study evaluating the safety tolerability and pharmacokinetics of CUDC-427, a potent, oral, monovalent IAP antagonist, in patients with refractory solid tumors
Clinical Cancer Research, ISSN: 15573265 10780432
Anthony W. Tolcher; Bendell; Kyriakos P. Papadopoulos; Howard A. Burris; Amita Patnaik; Wayne J. Fairbrother; Harvey Wong; Nageshwar Budha; Darbonne; Franklin V. Peale Jr.; Michael Mamounas; Stephanie Royer-Joo; Ron Yu; Chia C. Portera; Jeffery R. Infante
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Generation and Protective Ability of Influenza Virus-Specific Antibody-Dependent Cellular Cytotoxicity in Humans Elicited by Vaccination, Natural Infection, and Experimental Challenge
Journal of Infectious Diseases, ISSN: 15376613 00221899
Sinthujan Jegaskanda; Catherine Luke; Heather D. Hickman; Mark Y. Sangster; Wendy F. Wieland-Alter; Jacqueline McBride; Jon W. Yewdell; Peter Wright; John Treanor; Carrie M. Rosenberger; Kanta Subbarao
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Design and evaluation of 1,7-naphthyridones as novel KDM5 inhibitors
Bioorganic and Medicinal Chemistry Letters, ISSN: 14643405 0960894X
Sharada Labadie; Peter Dragovich; Richard T Cummings; Gauri Deshmukh; Amy Gustafson; Ning Han; Jean-Christophe Harmange; James R. Kiefer; Yue Li; Jun Liang; Bianca M. Liederer; Yichin Liu; Wanda Manieri; Weifeng Mao; Lesley J. Murray; Daniel F. Ortwine; Patrick Trojer; Erica Vanderporten; Maia Vinogradova; Li Wen
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Recent progress on nuclear receptor RORγ modulators
Bioorganic and Medicinal Chemistry Letters, ISSN: 14643405 0960894X
Patrick Cyr; Sarah M. Bronner; James J. Crawford
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Discovery of oxa-sultams as RORc inverse agonists showing reduced lipophilicity, improved selectivity and favorable ADME properties
Bioorganic and Medicinal Chemistry Letters, ISSN: 14643405 0960894X
Olivier René; Benjamin P. Fauber; Adrian Barnard; Kerry Chapman; Yuzhong Deng; Celine Eidenschenk; Christine Everett; Alberto Gobbi; Adam R. Johnson; Hank La; Maxine Norman; Gary Salmon; Susan Summerhill; Harvey Wong
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Validation of a treatment satisfaction questionnaire in non-hodgkin lymphoma: Assessing the change from intravenous to subcutaneous administration of rituximab
Patient Preference and Adherence, ISSN: 1177889X
Christina Theodore-Oklota; Louise Humphrey; Christof Wiesner; Gabriel Schnetzler; Stacie Hudgens; Alicyn K. Campbell
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